DK72593D0 - Rekombinant protein - Google Patents

Rekombinant protein

Info

Publication number
DK72593D0
DK72593D0 DK93725A DK72593A DK72593D0 DK 72593 D0 DK72593 D0 DK 72593D0 DK 93725 A DK93725 A DK 93725A DK 72593 A DK72593 A DK 72593A DK 72593 D0 DK72593 D0 DK 72593D0
Authority
DK
Denmark
Prior art keywords
polypeptide
recombinant protein
contg
new
systems
Prior art date
Application number
DK93725A
Other languages
Danish (da)
English (en)
Inventor
Torbjoern Egelrud
Lennart Hansson
Original Assignee
Symbicom Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbicom Ab filed Critical Symbicom Ab
Priority to DK93725A priority Critical patent/DK72593D0/da
Publication of DK72593D0 publication Critical patent/DK72593D0/da
Priority to EP94917764A priority patent/EP0703985B1/en
Priority to ES03078393T priority patent/ES2256669T3/es
Priority to CZ19953335A priority patent/CZ289600B6/cs
Priority to DK03078393T priority patent/DK1398326T3/da
Priority to JP50261695A priority patent/JP3542804B2/ja
Priority to ES94917764T priority patent/ES2208656T3/es
Priority to AU69352/94A priority patent/AU684518B2/en
Priority to UA95125281A priority patent/UA45314C2/uk
Priority to DK94917764T priority patent/DK0703985T3/da
Priority to PCT/IB1994/000166 priority patent/WO1995000651A1/en
Priority to RU96102761/13A priority patent/RU2160312C2/ru
Priority to US08/557,146 priority patent/US5834290A/en
Priority to CA002165197A priority patent/CA2165197C/en
Priority to DE69434612T priority patent/DE69434612T2/de
Priority to KR1019950705748A priority patent/KR100379207B1/ko
Priority to HU9503618A priority patent/HU220339B/hu
Priority to AT94917764T priority patent/ATE252884T1/de
Priority to CNB941929604A priority patent/CN100457908C/zh
Priority to SK1586-95A priority patent/SK284599B6/sk
Priority to DE69433280T priority patent/DE69433280T2/de
Priority to EP03078393A priority patent/EP1398326B1/en
Priority to BR9407015A priority patent/BR9407015A/pt
Priority to PL94312189A priority patent/PL178589B1/pl
Priority to AT03078393T priority patent/ATE315584T1/de
Priority to NO19955110A priority patent/NO322728B1/no
Priority to FI956075A priority patent/FI119027B/fi
Priority to US09/154,344 priority patent/US5981256A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/86—Products or compounds obtained by genetic engineering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Processing Of Solid Wastes (AREA)
  • Cosmetics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK93725A 1993-06-18 1993-06-18 Rekombinant protein DK72593D0 (da)

Priority Applications (28)

Application Number Priority Date Filing Date Title
DK93725A DK72593D0 (da) 1993-06-18 1993-06-18 Rekombinant protein
AT03078393T ATE315584T1 (de) 1993-06-18 1994-06-20 Monoklonale antikörper gegen recombinantes stratum corneum chymotryptisches enzym (scce)
US08/557,146 US5834290A (en) 1993-06-18 1994-06-20 Recombinant stratum corneum chymotryptic enzyme (SCCE)
DE69434612T DE69434612T2 (de) 1993-06-18 1994-06-20 Monoklonale Antikörper gegen recombinantes Stratum Corneum chymotryptisches Enzym (SCCE)
CZ19953335A CZ289600B6 (cs) 1993-06-18 1994-06-20 Izolovaná nukleová kyselina, replikovatelný vektor exprese, plazmid, savčí buňka nebo buněčná linie, polypeptid, způsob přípravy tohoto polypeptidu a farmaceutický přípravek s jeho obsahem
DK03078393T DK1398326T3 (da) 1993-06-18 1994-06-20 Monoklonale antistoffer mod rekombinant stratum corneum chymotryptisk enzym (SCCE)
JP50261695A JP3542804B2 (ja) 1993-06-18 1994-06-20 組換え角質層キモトリプシン酵素（ｓｃｃｅ）
ES94917764T ES2208656T3 (es) 1993-06-18 1994-06-20 Enzima quimotriptica del estrato corneo (scce) recombinante.
AU69352/94A AU684518B2 (en) 1993-06-18 1994-06-20 Recombinant stratum corneum chymotryptic enzyme (SCCE)
UA95125281A UA45314C2 (uk) 1993-06-18 1994-06-20 Фрагмент днк, що кодує поліпептид, який володіє активністю хімотрипсинового ензиму рогівкового шару (scce), поліпептид, що володіє активністю scce, фрагмент днк, експресуюча система (варіанти), вектор експресії, що експресується, плазміда, спосіб одержання поліпептиду, що володіє активністю scce
DK94917764T DK0703985T3 (da) 1993-06-18 1994-06-20 Rekombinant stratum corneum-chymotryptisk enzym (SCCE)
PCT/IB1994/000166 WO1995000651A1 (en) 1993-06-18 1994-06-20 Recombinant stratum corneum chymotryptic enzyme (scce)
RU96102761/13A RU2160312C2 (ru) 1993-06-18 1994-06-20 Выделенная нуклеиновая кислота, плазмида, реплицируемый вектор экспрессии, трансформированная линия клеток мыши 127, полипептид, способ получения предшественника полипептида, обладающего активностью scce, фармацевтическая композиция для лечения нарушений, связанных с кератинизацией
EP94917764A EP0703985B1 (en) 1993-06-18 1994-06-20 Recombinant stratum corneum chymotryptic enzyme (scce)
CA002165197A CA2165197C (en) 1993-06-18 1994-06-20 Recombinant stratum corneum chymotryptic enzyme (scce)
ES03078393T ES2256669T3 (es) 1993-06-18 1994-06-20 Anticuerpos monoclonales contra la enzima quimotriptica del estrato corneo (scce) recombinante.
KR1019950705748A KR100379207B1 (ko) 1993-06-18 1994-06-20 재조합각질층키모트립신형효소(scce)
HU9503618A HU220339B (hu) 1993-06-18 1994-06-20 Rekombináns stratum corneum kimotriptikus enzimet (SCCE) kódoló izolált nukleotid-szekvencia, ezt tartalmazó vektor és nem humán gazdaszervezet és eljárás előállítására
AT94917764T ATE252884T1 (de) 1993-06-18 1994-06-20 Rekombinantes stratum corneum chymotypisches enzym ( scce)
CNB941929604A CN100457908C (zh) 1993-06-18 1994-06-20 重组角质层胰凝乳蛋白酶(scce)
SK1586-95A SK284599B6 (sk) 1993-06-18 1994-06-20 Rekombinantný stratum corneum chymotryptický enzým (SCCE) a nukleotidová sekvencia kódujúca enzým, spôsob jeho prípravy, farmaceutický prípravok s jeho obsahom a jeho použitie
DE69433280T DE69433280T2 (de) 1993-06-18 1994-06-20 Rekombinantes stratum corneum chymotypisches enzym ( scce)
EP03078393A EP1398326B1 (en) 1993-06-18 1994-06-20 Monoclonal antibodies against recombinant stratum corneum chymotryptic enzyme (SCCE)
BR9407015A BR9407015A (pt) 1993-06-18 1994-06-20 Sequência de nucleotideos sistema de expressão vetor de expressão replicável plasmideo designado ps500 organismo não humano polipeptídeo processo para produzir um polipeptídeo composições farmacêutica e cosmética ou de cuidado da pele uso de um polipeptídeo processo para tratar e/ou evitar as várias ictioses acne psoriase ou outras doenças inflamatórias da pele como eczemas uso de um composto processos para tratar e/ou evitar as doenças de pênfigo autoimunes ou doenças acantolitícas como pênfico
PL94312189A PL178589B1 (pl) 1993-06-18 1994-06-20 Izolowany kwas nukleinowy, zdolny do replikacji wektor ekspresyjny, plazmid, komórka ssaka, polipeptyd i kompozycja farmaceutyczna do leczenia chorób skóry
NO19955110A NO322728B1 (no) 1993-06-18 1995-12-15 Nukleotidsekvens kodende for rekombinant stratum corneum chymotryptisk enzym (SCCE), samt replikerbar ekspresjonsvektor, plasmid, vertscelle, fremgangsmater, diagnostisk middel, sammensetninger og anvendelser derav.
FI956075A FI119027B (fi) 1993-06-18 1995-12-18 Rekombinantti sarveiskerroksen kymotryptinen entsyymi (SCCE)
US09/154,344 US5981256A (en) 1993-06-18 1998-09-16 Recombinant stratum corneum chymotryptic enzyme (SCCE)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93725A DK72593D0 (da) 1993-06-18 1993-06-18 Rekombinant protein

Publications (1)

Publication Number Publication Date
DK72593D0 true DK72593D0 (da) 1993-06-18

Family

ID=8096824

Family Applications (3)

Application Number Title Priority Date Filing Date
DK93725A DK72593D0 (da) 1993-06-18 1993-06-18 Rekombinant protein
DK94917764T DK0703985T3 (da) 1993-06-18 1994-06-20 Rekombinant stratum corneum-chymotryptisk enzym (SCCE)
DK03078393T DK1398326T3 (da) 1993-06-18 1994-06-20 Monoklonale antistoffer mod rekombinant stratum corneum chymotryptisk enzym (SCCE)

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK94917764T DK0703985T3 (da) 1993-06-18 1994-06-20 Rekombinant stratum corneum-chymotryptisk enzym (SCCE)
DK03078393T DK1398326T3 (da) 1993-06-18 1994-06-20 Monoklonale antistoffer mod rekombinant stratum corneum chymotryptisk enzym (SCCE)

Country Status (21)

Country Link
US (2) US5834290A (fi)
EP (2) EP0703985B1 (fi)
JP (1) JP3542804B2 (fi)
KR (1) KR100379207B1 (fi)
CN (1) CN100457908C (fi)
AT (2) ATE252884T1 (fi)
AU (1) AU684518B2 (fi)
BR (1) BR9407015A (fi)
CA (1) CA2165197C (fi)
CZ (1) CZ289600B6 (fi)
DE (2) DE69434612T2 (fi)
DK (3) DK72593D0 (fi)
ES (2) ES2208656T3 (fi)
FI (1) FI119027B (fi)
HU (1) HU220339B (fi)
NO (1) NO322728B1 (fi)
PL (1) PL178589B1 (fi)
RU (1) RU2160312C2 (fi)
SK (1) SK284599B6 (fi)
UA (1) UA45314C2 (fi)
WO (1) WO1995000651A1 (fi)

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DK72593D0 (da) * 1993-06-18 1993-06-18 Symbicom Ab Rekombinant protein
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US6294344B1 (en) * 1997-03-19 2001-09-25 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US6627403B2 (en) * 1997-03-19 2003-09-30 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US6316213B1 (en) * 1997-03-19 2001-11-13 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian, breast and lung cancer
US5962300A (en) 1997-03-26 1999-10-05 Incyte Pharmaceuticals, Inc. Human kallikrein
FR2761363B1 (fr) * 1997-03-28 1999-11-26 Oreal Polypeptide purifie de l'epiderme et son utilisation
JP2002514220A (ja) * 1997-05-12 2002-05-14 セイジ、ファーマスーティカルズ、インク 熱傷処置および感染防止のための局部スプレー
EP0898962A1 (en) * 1997-08-28 1999-03-03 Becton, Dickinson and Company Transdermal patches and methods for inactivating skin proteases
US6589770B1 (en) 1997-10-03 2003-07-08 The Procter & Gamble Company Keratinocyte derived protease
EP1019514B1 (en) * 1997-10-03 2005-12-07 The Procter & Gamble Company A keratinocyte derived protease
US6262249B1 (en) 1998-06-23 2001-07-17 Chiron Corporation Pancreatic cancer genes
US20050053983A1 (en) * 1998-11-20 2005-03-10 Fuso Pharmaceutical Industries, Ltd. Novel serine protease BSSP4
SE9900431D0 (sv) * 1999-02-09 1999-02-09 Johan Stenflo Monoklonal antikropp
US6420157B1 (en) * 1999-04-30 2002-07-16 Ortho-Mcneil Pharmaceutical, Inc. Zymogen activation system
US6485957B1 (en) * 1999-04-30 2002-11-26 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding the human serine protease EOS
US6426199B1 (en) * 1999-08-31 2002-07-30 Ortho-Mcneil Pharmaceutical, Inc. Dna
US6458564B1 (en) * 1999-08-31 2002-10-01 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding the human serine protease T
JP2003528904A (ja) * 2000-04-04 2003-09-30 カラー アクセス，インコーポレイティド 皮膚の脂質バリア機能を改善するための組成物
EP1367886B1 (en) * 2001-02-09 2011-07-13 Torbjörn Egelrud Scce transgenic mice and their use as models of human disease
US7019194B2 (en) 2001-02-09 2006-03-28 Lennart Hansson SCCE modified transgenic mammals and their use as models of human disease
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WO2005075667A1 (en) * 2004-02-03 2005-08-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with kallikrein 7 (klk7)
WO2005085469A2 (en) * 2004-03-09 2005-09-15 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with rho-associated protein kinase 1 (rock1)
WO2008063563A2 (en) 2006-11-16 2008-05-29 Transderm, Inc. Methods of treating keratin hyperproliferation disorders using mtor inhibitors
US8476243B2 (en) 2006-12-29 2013-07-02 Transderm, Inc. Methods and compositions for treating keratin hyperproliferative disorders
FR2925312B1 (fr) * 2007-12-19 2016-12-02 Oreal Utilisation cosmetique de proteines de type desmogleine i
US8466335B2 (en) 2010-04-26 2013-06-18 The Procter & Gamble Company Personal care product
US8685309B2 (en) 2010-04-26 2014-04-01 The Procter & Gamble Company Method for making a personal care product
TWI556737B (zh) 2011-02-11 2016-11-11 陶氏農業科學公司 改良的殺蟲劑配方
DK2948134T3 (da) 2013-01-24 2020-06-02 Palvella Therapeutics Inc Sammensætninger til transdermal indgivelse af mtor-inhibitorer
RU2585960C1 (ru) * 2015-02-17 2016-06-10 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт медицины труда" (ФГБНУ "НИИ МТ") Способ определения наследственной предрасположенности к нарушению барьерной функции кожи
JP7108631B2 (ja) 2017-01-06 2022-07-28 パルヴェラ セラピューティクス、インク． ｍＴＯＲ阻害剤の無水組成物およびその使用方法
US20200040103A1 (en) 2018-03-14 2020-02-06 Genentech, Inc. Anti-klk5 antibodies and methods of use
CN108421034A (zh) * 2018-04-24 2018-08-21 济南磐升生物技术有限公司 激肽释放酶7在皮肤创伤愈合中的应用
EP3802568A4 (en) * 2018-06-08 2022-07-13 The Board of Regents of the University of Oklahoma PEPTIDE THERAPEUTIC AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND RELATED CONDITIONS
JP2021530463A (ja) 2018-07-02 2021-11-11 パルヴェラ セラピューティクス、インク． ｍＴＯＲ阻害剤の無水組成物および使用方法
JP2022549087A (ja) * 2019-09-18 2022-11-24 ジェネンテック， インコーポレイテッド 抗ｋｌｋ７抗体、抗ｋｌｋ５抗体、多重特異性抗ｋｌｋ５／ｋｌｋ７抗体および使用方法
BR102020009679A2 (pt) * 2020-05-14 2021-11-23 Fundação Universidade Federal Do Abc - Ufabc Anticorpos recombinantes humanos para inibição da calicreína tecidual humana 7 (klk7) e uso em doenças relacionadas ao processo de descamação da pele
GB202018320D0 (en) * 2020-11-20 2021-01-06 Univ Newcastle Methods of producing recombinant complement proteins
CN117062839A (zh) * 2021-03-12 2023-11-14 基因泰克公司 抗klk7抗体、抗klk5抗体、多特异性抗klk5/klk7抗体和使用方法

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DK72593D0 (da) * 1993-06-18 1993-06-18 Symbicom Ab Rekombinant protein
CA2217492A1 (en) * 1995-04-04 1996-10-10 Edward Marion Johnstone Amyloid precursor protein protease

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EP0703985B1 (en) 2003-10-29
AU684518B2 (en) 1997-12-18
NO955110L (no) 1996-02-15
HU220339B (hu) 2001-12-28
DE69433280D1 (de) 2003-12-04
CA2165197A1 (en) 1995-01-05
BR9407015A (pt) 1996-09-10
RU2160312C2 (ru) 2000-12-10
ES2208656T3 (es) 2004-06-16
EP0703985A1 (en) 1996-04-03
CZ333595A3 (en) 1997-03-12
KR100379207B1 (ko) 2003-09-26
AU6935294A (en) 1995-01-17
CA2165197C (en) 2009-02-10
JP3542804B2 (ja) 2004-07-14
EP1398326A2 (en) 2004-03-17
CN1128047A (zh) 1996-07-31
ATE252884T1 (de) 2003-11-15
DE69434612T2 (de) 2006-10-05
HUT74835A (en) 1997-02-28
FI956075A (fi) 1996-02-16
WO1995000651A1 (en) 1995-01-05
JPH08511431A (ja) 1996-12-03
US5834290A (en) 1998-11-10
DE69433280T2 (de) 2004-07-22
US5981256A (en) 1999-11-09
DK0703985T3 (da) 2004-02-23
DK1398326T3 (da) 2006-05-22
EP1398326A3 (en) 2004-03-31
SK284599B6 (sk) 2005-07-01
UA45314C2 (uk) 2002-04-15
NO322728B1 (no) 2006-12-04
DE69434612D1 (de) 2006-04-06
FI956075A0 (fi) 1995-12-18
SK158695A3 (en) 1997-02-05
FI119027B (fi) 2008-06-30
PL312189A1 (en) 1996-04-01
CN100457908C (zh) 2009-02-04
EP1398326B1 (en) 2006-01-11
NO955110D0 (no) 1995-12-15
ES2256669T3 (es) 2006-07-16
CZ289600B6 (cs) 2002-03-13
HU9503618D0 (en) 1996-02-28
ATE315584T1 (de) 2006-02-15
PL178589B1 (pl) 2000-05-31

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