DK1398326T3 - Monoklonale antistoffer mod rekombinant stratum corneum chymotryptisk enzym (SCCE) - Google Patents

Monoklonale antistoffer mod rekombinant stratum corneum chymotryptisk enzym (SCCE)

Info

Publication number
DK1398326T3
DK1398326T3 DK03078393T DK03078393T DK1398326T3 DK 1398326 T3 DK1398326 T3 DK 1398326T3 DK 03078393 T DK03078393 T DK 03078393T DK 03078393 T DK03078393 T DK 03078393T DK 1398326 T3 DK1398326 T3 DK 1398326T3
Authority
DK
Denmark
Prior art keywords
scce
stratum corneum
monoclonal antibodies
antibodies against
chymotryptic enzyme
Prior art date
Application number
DK03078393T
Other languages
English (en)
Inventor
Torbjoern Egelrud
Lennart Hansson
Original Assignee
Lennart Hansson
Torbjoern Egelrud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lennart Hansson, Torbjoern Egelrud filed Critical Lennart Hansson
Application granted granted Critical
Publication of DK1398326T3 publication Critical patent/DK1398326T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/86—Products or compounds obtained by genetic engineering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Processing Of Solid Wastes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK03078393T 1993-06-18 1994-06-20 Monoklonale antistoffer mod rekombinant stratum corneum chymotryptisk enzym (SCCE) DK1398326T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK93725A DK72593D0 (da) 1993-06-18 1993-06-18 Rekombinant protein
EP03078393A EP1398326B1 (en) 1993-06-18 1994-06-20 Monoclonal antibodies against recombinant stratum corneum chymotryptic enzyme (SCCE)
EP94917764A EP0703985B1 (en) 1993-06-18 1994-06-20 Recombinant stratum corneum chymotryptic enzyme (scce)

Publications (1)

Publication Number Publication Date
DK1398326T3 true DK1398326T3 (da) 2006-05-22

Family

ID=8096824

Family Applications (3)

Application Number Title Priority Date Filing Date
DK93725A DK72593D0 (da) 1993-06-18 1993-06-18 Rekombinant protein
DK03078393T DK1398326T3 (da) 1993-06-18 1994-06-20 Monoklonale antistoffer mod rekombinant stratum corneum chymotryptisk enzym (SCCE)
DK94917764T DK0703985T3 (da) 1993-06-18 1994-06-20 Rekombinant stratum corneum-chymotryptisk enzym (SCCE)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK93725A DK72593D0 (da) 1993-06-18 1993-06-18 Rekombinant protein

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK94917764T DK0703985T3 (da) 1993-06-18 1994-06-20 Rekombinant stratum corneum-chymotryptisk enzym (SCCE)

Country Status (21)

Country Link
US (2) US5834290A (da)
EP (2) EP0703985B1 (da)
JP (1) JP3542804B2 (da)
KR (1) KR100379207B1 (da)
CN (1) CN100457908C (da)
AT (2) ATE252884T1 (da)
AU (1) AU684518B2 (da)
BR (1) BR9407015A (da)
CA (1) CA2165197C (da)
CZ (1) CZ289600B6 (da)
DE (2) DE69433280T2 (da)
DK (3) DK72593D0 (da)
ES (2) ES2256669T3 (da)
FI (1) FI119027B (da)
HU (1) HU220339B (da)
NO (1) NO322728B1 (da)
PL (1) PL178589B1 (da)
RU (1) RU2160312C2 (da)
SK (1) SK284599B6 (da)
UA (1) UA45314C2 (da)
WO (1) WO1995000651A1 (da)

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US5976556A (en) * 1996-06-13 1999-11-02 Active Organics, Inc. Combination of acid protease enzymes and acidic buffers and uses thereof
GB9616139D0 (en) * 1996-08-01 1996-09-11 Grampian Pharm Ltd Veterinary treatments
CA2280747A1 (en) * 1997-02-12 1998-11-05 Johnson & Johnson Consumer Companies, Inc. Serine protease and topical retinoid compositions
US5856139A (en) * 1997-03-11 1999-01-05 Incyte Pharmaceuticals, Inc. Proline-rich acidic protein
US6627403B2 (en) * 1997-03-19 2003-09-30 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US6294344B1 (en) * 1997-03-19 2001-09-25 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US6316213B1 (en) * 1997-03-19 2001-11-13 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian, breast and lung cancer
US5962300A (en) 1997-03-26 1999-10-05 Incyte Pharmaceuticals, Inc. Human kallikrein
FR2761363B1 (fr) * 1997-03-28 1999-11-26 Oreal Polypeptide purifie de l'epiderme et son utilisation
WO1998051273A1 (en) * 1997-05-12 1998-11-19 Sage Pharmaceuticals, Inc. Topical spray for burn treatment and anti-infection
EP0898962A1 (en) * 1997-08-28 1999-03-03 Becton, Dickinson and Company Transdermal patches and methods for inactivating skin proteases
ATE312182T1 (de) * 1997-10-03 2005-12-15 Procter & Gamble Eine protease aus keratinocyten
US6589770B1 (en) 1997-10-03 2003-07-08 The Procter & Gamble Company Keratinocyte derived protease
US6262249B1 (en) 1998-06-23 2001-07-17 Chiron Corporation Pancreatic cancer genes
US20050053983A1 (en) * 1998-11-20 2005-03-10 Fuso Pharmaceutical Industries, Ltd. Novel serine protease BSSP4
SE9900431D0 (sv) * 1999-02-09 1999-02-09 Johan Stenflo Monoklonal antikropp
US6485957B1 (en) 1999-04-30 2002-11-26 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding the human serine protease EOS
US6420157B1 (en) * 1999-04-30 2002-07-16 Ortho-Mcneil Pharmaceutical, Inc. Zymogen activation system
US6426199B1 (en) * 1999-08-31 2002-07-30 Ortho-Mcneil Pharmaceutical, Inc. Dna
US6458564B1 (en) * 1999-08-31 2002-10-01 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding the human serine protease T
JP2003528904A (ja) * 2000-04-04 2003-09-30 カラー アクセス，インコーポレイティド 皮膚の脂質バリア機能を改善するための組成物
US7019194B2 (en) 2001-02-09 2006-03-28 Lennart Hansson SCCE modified transgenic mammals and their use as models of human disease
DK1367886T3 (da) * 2001-02-09 2011-10-24 Torbjoern Egelrud SCCE-transgene mus og deres anvendelse som modeller for humane sygdomme
GB0128629D0 (en) * 2001-11-29 2002-01-23 Univ Sheffield Method
AU2002952597A0 (en) * 2002-11-11 2002-11-28 Schering-Plough Pty. Limited Topical parasiticide formulations and methods of treatment
CN100518740C (zh) * 2003-06-06 2009-07-29 阿里克斯股份公司 杂环化合物作为scce抑制剂的制药用途
US20050106586A1 (en) * 2003-06-13 2005-05-19 Mount Sinai Hospital Detection of neurodegenerative diseases
WO2005075667A1 (en) * 2004-02-03 2005-08-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with kallikrein 7 (klk7)
WO2005085469A2 (en) * 2004-03-09 2005-09-15 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with rho-associated protein kinase 1 (rock1)
US9205080B2 (en) 2006-11-16 2015-12-08 Transderm, Inc. Methods of treating keratin hyperproliferation disorders using mTOR inhibitors
US8476243B2 (en) 2006-12-29 2013-07-02 Transderm, Inc. Methods and compositions for treating keratin hyperproliferative disorders
FR2925312B1 (fr) * 2007-12-19 2016-12-02 Oreal Utilisation cosmetique de proteines de type desmogleine i
US8466335B2 (en) 2010-04-26 2013-06-18 The Procter & Gamble Company Personal care product
US8685309B2 (en) 2010-04-26 2014-04-01 The Procter & Gamble Company Method for making a personal care product
TWI556737B (zh) 2011-02-11 2016-11-11 陶氏農業科學公司 改良的殺蟲劑配方
WO2014117035A1 (en) 2013-01-24 2014-07-31 Transderm, Inc. COMPOSITIONS FOR TRANSDERMAL DELIVERY OF mTOR INHIBITORS
RU2585960C1 (ru) * 2015-02-17 2016-06-10 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт медицины труда" (ФГБНУ "НИИ МТ") Способ определения наследственной предрасположенности к нарушению барьерной функции кожи
CA3049402A1 (en) 2017-01-06 2018-07-12 Palvella Therapeutics Llc Anhydrous compositions of mtor inhibitors and methods of use
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JP2021525785A (ja) * 2018-06-08 2021-09-27 ザ ボード オブ リージェンツ オブ ザ ユニヴァーシティ オブ オクラホマ アルツハイマー病および関連状態を処置するためのペプチド治療薬
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CA3150999A1 (en) * 2019-09-18 2021-03-25 James Thomas Koerber Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
BR102020009679A2 (pt) * 2020-05-14 2021-11-23 Fundação Universidade Federal Do Abc - Ufabc Anticorpos recombinantes humanos para inibição da calicreína tecidual humana 7 (klk7) e uso em doenças relacionadas ao processo de descamação da pele
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JP2024512377A (ja) * 2021-03-12 2024-03-19 ジェネンテック， インコーポレイテッド 抗ｋｌｋ７抗体、抗ｋｌｋ５抗体、多重特異性抗ｋｌｋ５／ｋｌｋ７抗体、及び使用方法

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Also Published As

Publication number Publication date
CN100457908C (zh) 2009-02-04
HU220339B (hu) 2001-12-28
EP1398326B1 (en) 2006-01-11
NO322728B1 (no) 2006-12-04
FI956075A (fi) 1996-02-16
ES2208656T3 (es) 2004-06-16
CA2165197C (en) 2009-02-10
DK72593D0 (da) 1993-06-18
NO955110D0 (no) 1995-12-15
US5981256A (en) 1999-11-09
ATE315584T1 (de) 2006-02-15
DE69434612D1 (de) 2006-04-06
DE69433280D1 (de) 2003-12-04
FI119027B (fi) 2008-06-30
CN1128047A (zh) 1996-07-31
PL312189A1 (en) 1996-04-01
DE69433280T2 (de) 2004-07-22
CZ333595A3 (en) 1997-03-12
DE69434612T2 (de) 2006-10-05
BR9407015A (pt) 1996-09-10
AU6935294A (en) 1995-01-17
EP0703985A1 (en) 1996-04-03
AU684518B2 (en) 1997-12-18
US5834290A (en) 1998-11-10
FI956075A0 (fi) 1995-12-18
DK0703985T3 (da) 2004-02-23
UA45314C2 (uk) 2002-04-15
RU2160312C2 (ru) 2000-12-10
EP1398326A2 (en) 2004-03-17
WO1995000651A1 (en) 1995-01-05
EP0703985B1 (en) 2003-10-29
JPH08511431A (ja) 1996-12-03
SK158695A3 (en) 1997-02-05
HU9503618D0 (en) 1996-02-28
EP1398326A3 (en) 2004-03-31
CZ289600B6 (cs) 2002-03-13
KR100379207B1 (ko) 2003-09-26
SK284599B6 (sk) 2005-07-01
JP3542804B2 (ja) 2004-07-14
HUT74835A (en) 1997-02-28
PL178589B1 (pl) 2000-05-31
ES2256669T3 (es) 2006-07-16
NO955110L (no) 1996-02-15
ATE252884T1 (de) 2003-11-15
CA2165197A1 (en) 1995-01-05

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