DK596085A - Plaster til afgivelse af aktivt stof - Google Patents

Plaster til afgivelse af aktivt stof Download PDF

Info

Publication number
DK596085A
DK596085A DK596085A DK596085A DK596085A DK 596085 A DK596085 A DK 596085A DK 596085 A DK596085 A DK 596085A DK 596085 A DK596085 A DK 596085A DK 596085 A DK596085 A DK 596085A
Authority
DK
Denmark
Prior art keywords
rubber
adhesive resin
layer
drug
polymer
Prior art date
Application number
DK596085A
Other languages
English (en)
Other versions
DK596085D0 (da
DK170060B1 (da
Inventor
G Cordes
M Wolff
Original Assignee
Schwarz Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schwarz Gmbh filed Critical Schwarz Gmbh
Publication of DK596085D0 publication Critical patent/DK596085D0/da
Publication of DK596085A publication Critical patent/DK596085A/da
Application granted granted Critical
Publication of DK170060B1 publication Critical patent/DK170060B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A61L15/585—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Saccharide Compounds (AREA)
DK596085A 1984-12-22 1985-12-20 Medicinsk plaster til afgivelse af aktivt stof samt fremgangsmåde til fremstilling deraf DK170060B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3447072 1984-12-22
DE3447072 1984-12-22

Publications (3)

Publication Number Publication Date
DK596085D0 DK596085D0 (da) 1985-12-20
DK596085A true DK596085A (da) 1986-06-23
DK170060B1 DK170060B1 (da) 1995-05-15

Family

ID=6253652

Family Applications (1)

Application Number Title Priority Date Filing Date
DK596085A DK170060B1 (da) 1984-12-22 1985-12-20 Medicinsk plaster til afgivelse af aktivt stof samt fremgangsmåde til fremstilling deraf

Country Status (19)

Country Link
US (1) US4668232A (da)
EP (1) EP0186019B1 (da)
JP (1) JPH06104623B2 (da)
KR (1) KR930002272B1 (da)
AT (1) ATE95430T1 (da)
AU (1) AU576650B2 (da)
CA (1) CA1255592A (da)
CS (1) CS270207B2 (da)
DD (1) DD243856A5 (da)
DE (1) DE3587616D1 (da)
DK (1) DK170060B1 (da)
ES (1) ES8702794A1 (da)
FI (1) FI82602C (da)
GR (1) GR853101B (da)
HU (1) HU195427B (da)
IE (1) IE60569B1 (da)
PH (1) PH22931A (da)
PT (1) PT81751B (da)
YU (1) YU46517B (da)

Families Citing this family (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883669A (en) * 1985-02-25 1989-11-28 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration
US5560922A (en) * 1986-05-30 1996-10-01 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process
EP0249343B1 (en) * 1986-06-13 1992-01-08 Alza Corporation Moisture activation of transdermal drug delivery system
US6139868A (en) * 1986-08-28 2000-10-31 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
JPH0744940B2 (ja) * 1986-12-24 1995-05-17 ライオン株式会社 口腔貼付用基材
US4788062A (en) * 1987-02-26 1988-11-29 Alza Corporation Transdermal administration of progesterone, estradiol esters, and mixtures thereof
US5071656A (en) * 1987-03-05 1991-12-10 Alza Corporation Delayed onset transdermal delivery device
DE3743945A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von stoffen, verfahren zu ihrer herstellung sowie ihre verwendung
US5273757A (en) * 1987-09-01 1993-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Apparatus for the delivery of substances, processes for the production thereof and use thereof
DE3743946A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung
US5306502A (en) * 1987-09-01 1994-04-26 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Apparatus for delivering nitroglycerin to the skin, processes for the production thereof and the use thereof
DE3743947A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur gesteuerten abgabe von nicotin, verfahren zu ihrer herstellung sowie ihre verwendung
US5059189A (en) * 1987-09-08 1991-10-22 E. R. Squibb & Sons, Inc. Method of preparing adhesive dressings containing a pharmaceutically active ingredient
JP2537062B2 (ja) * 1987-10-02 1996-09-25 株式会社資生堂 薬剤組成物
US4906475A (en) 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
GB8804164D0 (en) * 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
GB2232892B (en) * 1988-02-23 1991-07-24 John Mark Tucker Occlusive body for administering a physiologically active substance
US5474783A (en) 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US4814168A (en) * 1988-03-04 1989-03-21 Noven Pharmaceuticals, Inc. Transdermal multipolymer drug delivery system
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
EP0406315B1 (en) * 1988-03-24 1992-11-11 Bukh Meditec A/S Controlled release composition
AU622162B2 (en) * 1988-04-22 1992-04-02 Ciba-Geigy Ag Transdermal monolith systems
DE3823070A1 (de) * 1988-07-07 1990-02-22 Kettelhack Riker Pharma Gmbh Selbstklebendes heftpflaster
ES2062093T3 (es) * 1988-08-02 1994-12-16 Ciba Geigy Ag Emplasto de varias capas.
CA2000401C (en) * 1988-10-11 1996-05-28 Masato Azuma Percutaneous pharmaceutical preparation
EP0573133A1 (de) * 1988-10-27 1993-12-08 Schering Aktiengesellschaft Mittel zur transdermalen Applikation das Gestoden enthält
ZA899112B (en) * 1988-12-01 1990-08-29 Schering Corp Compositions for transdermal delivery of estradiol
DE3910543A1 (de) * 1989-04-01 1990-10-11 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
DE3933460A1 (de) * 1989-10-06 1991-04-18 Lohmann Therapie Syst Lts Oestrogenhaltiges wirkstoffpflaster
US5750136A (en) * 1989-11-03 1998-05-12 Riker Laboratories, Inc. Bioadhesive composition and patch
US5750134A (en) 1989-11-03 1998-05-12 Riker Laboratories, Inc. Bioadhesive composition and patch
US5248676A (en) * 1990-05-17 1993-09-28 Hisamitsu Pharmaceutical Co., Inc. Estradiol percutaneous administration preparations
US5455043A (en) * 1990-06-13 1995-10-03 Fischel-Ghodsian; Fariba Device for controlled release of vaporous medications through nasal route
US5071704A (en) * 1990-06-13 1991-12-10 Fischel Ghodsian Fariba Device for controlled release of vapors and scents
DE69312487T2 (de) * 1992-05-18 1997-11-27 Minnesota Mining & Mfg Einrichtung zur transmucosalen wirkstoffabgabe
DE4224325C1 (de) * 1992-07-23 1994-02-10 Sanol Arznei Schwarz Gmbh Wirkstoffpflaster für niedrigschmelzende und/oder flüchtige Wirkstoffe und Verfahren zu seiner Herstellung
US5989586A (en) * 1992-10-05 1999-11-23 Cygnus, Inc. Two-phase matrix for sustained release drug delivery device
DE4237453C1 (da) * 1992-11-06 1993-08-19 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
US5883115A (en) * 1992-11-09 1999-03-16 Pharmetrix Division Technical Chemicals & Products, Inc. Transdermal delivery of the eutomer of a chiral drug
DE4336557C2 (de) * 1993-05-06 1997-07-17 Lohmann Therapie Syst Lts Estradiolhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung
AU7396294A (en) 1993-06-25 1995-01-24 Alza Corporation Incorporating poly-n-vinyl amide in a transdermal system
DE4400770C1 (de) * 1994-01-13 1995-02-02 Lohmann Therapie Syst Lts Wirkstoffhaltiges Pflaster zur Abgabe von Estradiol mit mindestens einem Penetrationsverstärker, Verfahren zu seiner Herstellung und seine Verwendung
JPH07206710A (ja) * 1994-01-21 1995-08-08 Nitto Denko Corp 経皮投薬用テープ製剤
DE4429663C2 (de) * 1994-08-20 1997-09-11 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Hydrolyseschutz
DE19500662C2 (de) * 1995-01-12 2001-04-26 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster und seine Verwendung
JPH0912448A (ja) * 1995-04-28 1997-01-14 Read Chem Kk 薬物放出制御型経皮吸収製剤
AU708188B2 (en) * 1995-04-28 1999-07-29 Lead Chemical Co., Ltd. Release controlled transdermal therapeutic system
IL122432A (en) * 1995-06-07 2000-07-16 Cygnus Therapeutic Systems Transdermal patch for preventing ovulation
DE19533089C1 (de) 1995-09-07 1997-05-22 Hexal Ag Tacrin-Pflaster
DE19533772C1 (de) * 1995-09-12 1998-01-02 Hexal Ag Tacrin/Selegilin-Pflaster
JP4259613B2 (ja) 1996-02-13 2009-04-30 大日本住友製薬株式会社 ガラクトキシログルカンを用いるドラッグ・デリバリー・システム
US5800832A (en) * 1996-10-18 1998-09-01 Virotex Corporation Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
US5955097A (en) * 1996-10-18 1999-09-21 Virotex Corporation Pharmaceutical preparation applicable to mucosal surfaces and body tissues
US6290986B1 (en) 1996-10-24 2001-09-18 Pharmaceutical Applications Associates, Llc Method and composition for transdermal administration of pharmacologic agents
US6479074B2 (en) 1996-10-24 2002-11-12 Pharmaceutical Applications Associates Llc Methods and transdermal compositions for pain relief
US6572880B2 (en) 1996-10-24 2003-06-03 Pharmaceutical Applications Associates Llc Methods and transdermal compositions for pain relief
AU5155198A (en) * 1997-08-28 1999-03-22 Robert Murdock Method and composition for transdermal administration of pharmacologic agent
CA2302754C (en) * 1997-09-04 2011-11-08 Novoneuron, Inc. Noribogaine in the treatment of pain and drug addiction
US20050048102A1 (en) * 1997-10-16 2005-03-03 Virotex Corporation Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces
US6103266A (en) * 1998-04-22 2000-08-15 Tapolsky; Gilles H. Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues
ES2226394T3 (es) * 1998-05-22 2005-03-16 Novosis Ag Sistemas transdermales que contienen substancia activa que se libera de forma controlada en el tiempo.
DE19834007C1 (de) 1998-07-29 2000-02-24 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung
KR100336975B1 (ko) * 1998-08-11 2002-08-22 한국화학연구원 약물방출제어용패취
AU4543200A (en) * 1999-04-16 2000-11-02 Dittgen, Michael Pharmaceutical or cosmetic compositions for the local, intradermal application of hormones
AU5325000A (en) 1999-06-05 2000-12-28 David Houze Solubility enhancement of drugs in transdermal drug delivery systems and methodsof use
DE19943317C1 (de) * 1999-09-10 2001-03-15 Lohmann Therapie Syst Lts Kunststofffolien, insbesondere für die Verwendung in einem dermalen oder transdermalen therapeutischen System und Verfahren zu ihrer Herstellung
DE10003767A1 (de) 2000-01-28 2001-10-04 Beiersdorf Ag Hautfreundliches Wirkstoffpflaster zur transdermalen Verabreichung nichtsteroidaler Antirheumatika
DE10056009A1 (de) * 2000-11-11 2002-05-16 Beiersdorf Ag Hautfreundliches Wirkstoffpflaster zur transdermalen Verabreichung hyperämisierender Wirkstoffe
DE10114382A1 (de) * 2001-03-23 2002-09-26 Beiersdorf Ag Feuchtigkeitsaufnehmende Matrix auf Silikonbasis insbesondere zur Wundversorgung und/oder pharmazeutisch/kosmetischen Hautbehandlung
US6946142B2 (en) * 2001-06-23 2005-09-20 Lg Household & Healthcare Ltd. Multi-layer patches for teeth whitening
KR100448469B1 (ko) * 2001-10-26 2004-09-13 신풍제약주식회사 항염증제의 경피 조성물 및 장치
US8124122B2 (en) 2002-08-09 2012-02-28 Teikoku Seiyaku Co., Ltd. Female hormone-containing patch
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
US20050058688A1 (en) * 2003-02-22 2005-03-17 Lars Boerger Device for the treatment and prevention of disease, and methods related thereto
DE102004011686A1 (de) * 2004-03-10 2005-09-29 Novosis Ag Dermales oder transdermales therapeutisches System mit Matrixbestandteil aus nachwachsendem Rohrstoff
US20070106274A1 (en) * 2005-10-19 2007-05-10 Ayre Peter J Control systems for implantable medical devices
KR20080109841A (ko) 2006-03-10 2008-12-17 뉴로젠 코포레이션 피페라지닐 옥소알킬 테트라히드로이소퀴놀린 및 관련유사체
DE102006026578B4 (de) * 2006-06-08 2009-01-08 Lts Lohmann Therapie-Systeme Ag Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
RS54764B1 (sr) 2006-07-21 2016-10-31 Biodelivery Sciences Int Inc Sredstvo za transmukozalnu isporuku sa povećanim nakupljanjem
US7976951B2 (en) 2006-11-14 2011-07-12 Momentive Performance Materials Inc. Laminate containing an adhesive-forming composition
US7829116B2 (en) * 2006-11-14 2010-11-09 Momentive Performance Materials Inc. Adhesive-forming composition and blend of adhesives obtained therefrom
MX2009005478A (es) 2006-11-27 2009-08-12 Lundbeck & Co As H Derivados de heteroarilamida.
JP5242950B2 (ja) * 2007-06-15 2013-07-24 日東電工株式会社 ゲル組成物およびその用途
CA2662499A1 (en) * 2008-04-16 2009-10-16 Nitto Denko Corporation Transdermal drug administration device
US8701671B2 (en) 2011-02-04 2014-04-22 Joseph E. Kovarik Non-surgical method and system for reducing snoring
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
WO2011126910A2 (en) * 2010-03-30 2011-10-13 Algynomics Inc. Compositions and methods for the treatment of somatosensory disorders
US8716350B2 (en) 2010-03-30 2014-05-06 Algynomics Inc. Compositions and methods for the treatment of somatosensory disorders
US9394294B2 (en) 2010-05-11 2016-07-19 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8765737B1 (en) 2010-05-11 2014-07-01 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8362007B1 (en) 2010-05-11 2013-01-29 Demerx, Inc. Substituted noribogaine
US8637648B1 (en) 2010-06-22 2014-01-28 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US8802832B2 (en) 2010-06-22 2014-08-12 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US9586954B2 (en) 2010-06-22 2017-03-07 Demerx, Inc. N-substituted noribogaine prodrugs
US8741891B1 (en) 2010-06-22 2014-06-03 Demerx, Inc. N-substituted noribogaine prodrugs
RU2586296C2 (ru) 2010-07-23 2016-06-10 Демеркс, Инк. Композиции норибогаина
EP2481740B1 (en) 2011-01-26 2015-11-04 DemeRx, Inc. Methods and compositions for preparing noribogaine from voacangine
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US8703177B2 (en) 2011-08-18 2014-04-22 Biodelivery Sciences International, Inc. Abuse-resistant mucoadhesive devices for delivery of buprenorphine
US9617274B1 (en) 2011-08-26 2017-04-11 Demerx, Inc. Synthetic noribogaine
CA2855994A1 (en) 2011-12-09 2013-06-13 Demerx, Inc. Phosphate esters of noribogaine
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
AU2013212139A1 (en) 2012-01-25 2014-06-26 Demerx, Inc. Synthetic voacangine
US9150584B2 (en) 2012-01-25 2015-10-06 Demerx, Inc. Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
US9045481B2 (en) 2012-12-20 2015-06-02 Demerx, Inc. Substituted noribogaine
US8940728B2 (en) 2012-12-20 2015-01-27 Demerx, Inc. Substituted noribogaine
WO2014098877A1 (en) 2012-12-20 2014-06-26 Demerx, Inc. Substituted noribogaine
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US12005085B2 (en) 2013-12-20 2024-06-11 Seed Health, Inc. Probiotic method and composition for maintaining a healthy vaginal microbiome
CA2989550C (en) 2014-06-18 2023-08-08 Demerx, Inc. Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them
DE102018120505A1 (de) 2017-10-20 2019-04-25 Amw Gmbh Verhinderung der Kristallisation von Wirkstoffen in transdermalen Darreichungssystemen

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201211A (en) * 1977-07-12 1980-05-06 Alza Corporation Therapeutic system for administering clonidine transdermally
JPS56133381A (en) * 1980-03-25 1981-10-19 Nippon Kayaku Co Ltd Pressure-sensitive adhesive tape or sheet containing nitroglycerin
US4346709A (en) * 1980-11-10 1982-08-31 Alza Corporation Drug delivery devices comprising erodible polymer and erosion rate modifier
EP0055023A3 (en) * 1980-12-18 1982-12-15 E.R. Squibb & Sons, Inc. Antiseptic containing adhesive composition
JPS6059207B2 (ja) * 1981-03-13 1985-12-24 日東電工株式会社 複合製剤の製法
AU553343B2 (en) * 1981-08-10 1986-07-10 Advance Electrode Kabushikikaisya Absorbent adhesive bandage with medicament release
GR79183B (da) * 1983-04-27 1984-10-02 Lohmann Gmbh & Co Kg
DE3333240A1 (de) * 1983-09-12 1985-03-28 Schering AG, 1000 Berlin und 4709 Bergkamen Mittel zur transdermalen applikation von arzneimittelwirkstoffen
DE3347277A1 (de) * 1983-12-28 1985-07-11 Bayer Ag, 5090 Leverkusen Wirkstoffabgabesysteme
US4615699A (en) * 1985-05-03 1986-10-07 Alza Corporation Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes

Also Published As

Publication number Publication date
FI82602B (fi) 1990-12-31
YU46517B (sh) 1993-11-16
CS270207B2 (en) 1990-06-13
YU201685A (en) 1988-08-31
CA1255592A (en) 1989-06-13
FI855124A (fi) 1986-06-23
ES8702794A1 (es) 1987-01-16
ES550256A0 (es) 1987-01-16
PT81751A (en) 1986-01-02
IE60569B1 (en) 1994-07-27
JPS61155321A (ja) 1986-07-15
AU576650B2 (en) 1988-09-01
ATE95430T1 (de) 1993-10-15
PT81751B (pt) 1987-11-11
IE853282L (en) 1986-06-22
DD243856A5 (de) 1987-03-18
DE3587616D1 (de) 1993-11-11
FI82602C (fi) 1991-04-10
HUT40581A (en) 1987-01-28
CS964785A2 (en) 1989-10-13
EP0186019B1 (de) 1993-10-06
FI855124A0 (fi) 1985-12-20
HU195427B (en) 1988-05-30
PH22931A (en) 1989-01-24
DK596085D0 (da) 1985-12-20
GR853101B (da) 1986-04-15
KR860004638A (ko) 1986-07-11
JPH06104623B2 (ja) 1994-12-21
KR930002272B1 (ko) 1993-03-27
US4668232A (en) 1987-05-26
EP0186019A2 (de) 1986-07-02
EP0186019A3 (en) 1989-01-04
DK170060B1 (da) 1995-05-15
AU5146185A (en) 1986-07-17

Similar Documents

Publication Publication Date Title
DK596085D0 (da) Plaster til afgivelse af aktivt stof
MY109926A (en) Transdermal therapeutic system comprising galanthamine as active component
DE69427038D1 (de) Transdermales medikamentenverabreichungssystem
MY106628A (en) Estrogen-containing active substance plaster
YU47956B (sh) Postupak za izradu transdermalnog terapijskog sistema sa buprenorphinom kao aktivnim sastojkom
AU622775B2 (en) A plaster used as therapeutic system for the administration of active substances to the skin, which exhibits a graduated active substance release, process for the production of the plaster and the use thereof
FI951887A0 (fi) Laastarit haihtuvien, farmaseuttisesti vaikuttavien, kemiallisesti emäksisten aineiden antamiseen ihon läpi, ja menetelmä niiden valmistamiseksi
DK39189D0 (da) Transdermalt, terapeutisk virkende, farmaceutisk praeparat samt indretning til paafoering af praeparatet
MY110391A (en) Nitroglycerin-containing patch, a process for the production and the use thereof
AR003413A1 (es) Parches medicinales para la administracion transdermica de risperidona con liberacion controlada a traves de la piel intacta durante un periodo de tiempo prolongado
DE59506962D1 (de) Estradiol-tts mit wasserbindenden zusätzen
JPS577412A (en) Plaster
DE59504233D1 (de) Estradiol-tts mit wasserbindenden zusätzen
AU701327B2 (en) Preperation for the prophylaxis and/or treatment of wool and hair loss
ES2105334T3 (es) Sistema terapeutico percutaneo para la administracion de fisostigmina en la piel y el procedimiento para su obtencion.
CA2197867A1 (en) Oestradiol transdermal therapeutic system comprising hygroscopic additives

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired