DE59504233D1 - Estradiol-tts mit wasserbindenden zusätzen - Google Patents

Estradiol-tts mit wasserbindenden zusätzen

Info

Publication number
DE59504233D1
DE59504233D1 DE59504233T DE59504233T DE59504233D1 DE 59504233 D1 DE59504233 D1 DE 59504233D1 DE 59504233 T DE59504233 T DE 59504233T DE 59504233 T DE59504233 T DE 59504233T DE 59504233 D1 DE59504233 D1 DE 59504233D1
Authority
DE
Germany
Prior art keywords
water
binding additives
hydrophylic
additive
tts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59504233T
Other languages
English (en)
Inventor
Michael Horstmann
Walter Mueller
Hanshermann Franke
Thomas Pontzen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Priority to DE59504233T priority Critical patent/DE59504233D1/de
Application granted granted Critical
Publication of DE59504233D1 publication Critical patent/DE59504233D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
DE59504233T 1994-08-20 1995-08-12 Estradiol-tts mit wasserbindenden zusätzen Expired - Lifetime DE59504233D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE59504233T DE59504233D1 (de) 1994-08-20 1995-08-12 Estradiol-tts mit wasserbindenden zusätzen

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4429664A DE4429664C2 (de) 1994-08-20 1994-08-20 Estradiol-TTS mit wasserbindenden Zusätzen und Verfahren zu seiner Herstellung
DE59504233T DE59504233D1 (de) 1994-08-20 1995-08-12 Estradiol-tts mit wasserbindenden zusätzen
PCT/EP1995/003202 WO1996005815A1 (de) 1994-08-20 1995-08-12 Estradiol-tts mit wasserbindenden zusätzen

Publications (1)

Publication Number Publication Date
DE59504233D1 true DE59504233D1 (de) 1998-12-17

Family

ID=6526229

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4429664A Expired - Fee Related DE4429664C2 (de) 1994-08-20 1994-08-20 Estradiol-TTS mit wasserbindenden Zusätzen und Verfahren zu seiner Herstellung
DE59504233T Expired - Lifetime DE59504233D1 (de) 1994-08-20 1995-08-12 Estradiol-tts mit wasserbindenden zusätzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE4429664A Expired - Fee Related DE4429664C2 (de) 1994-08-20 1994-08-20 Estradiol-TTS mit wasserbindenden Zusätzen und Verfahren zu seiner Herstellung

Country Status (21)

Country Link
EP (1) EP0776197B1 (de)
JP (1) JPH10504314A (de)
KR (1) KR100374476B1 (de)
CN (1) CN1073413C (de)
AT (1) ATE173163T1 (de)
AU (1) AU700119B2 (de)
CA (1) CA2197865C (de)
CZ (1) CZ50897A3 (de)
DE (2) DE4429664C2 (de)
DK (1) DK0776197T3 (de)
ES (1) ES2126308T3 (de)
FI (1) FI118721B (de)
HU (1) HUT77093A (de)
IL (1) IL114948A (de)
NO (1) NO970553D0 (de)
NZ (1) NZ291449A (de)
PL (1) PL180943B1 (de)
SI (1) SI0776197T1 (de)
SK (1) SK280299B6 (de)
WO (1) WO1996005815A1 (de)
ZA (1) ZA956926B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19600347A1 (de) * 1996-01-08 1997-07-10 Lohmann Therapie Syst Lts Hauthaftende pharmazeutische Zubereitung, insbesondere TTS zur Abgabe von 17-beta-Estradiol an den menschlichen Organismus
US6623763B2 (en) 1996-01-08 2003-09-23 Lts Lohmann Therape-System Ag Pharmaceutical preparation adhering to the skin, in particular a transdermal therapeutic system for the release of 17-β-estradiol to the human organism
GB9720470D0 (en) 1997-09-25 1997-11-26 Ethical Pharmaceuticals South Inhibition of crystallization in transdermal devices
DE19827732A1 (de) * 1998-06-22 1999-12-23 Rottapharm Bv Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6712090A (en) * 1989-10-13 1991-05-16 Watson Laboratories, Inc. Drug delivery systems and matrix therefor
DE4223360C1 (de) * 1992-07-16 1993-04-08 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
DE4237453C1 (de) * 1992-11-06 1993-08-19 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
DE4309830C1 (de) * 1993-03-26 1994-05-05 Lohmann Therapie Syst Lts Wirkstoffpflaster für die Abgabe von Estradiol an die Haut

Also Published As

Publication number Publication date
AU700119B2 (en) 1998-12-24
DE4429664A1 (de) 1996-02-22
SI0776197T1 (en) 1999-04-30
HUT77093A (hu) 1998-03-02
PL180943B1 (pl) 2001-05-31
ATE173163T1 (de) 1998-11-15
KR970705380A (ko) 1997-10-09
CZ50897A3 (en) 1997-06-11
DK0776197T3 (da) 1999-07-26
ES2126308T3 (es) 1999-03-16
KR100374476B1 (ko) 2003-04-23
FI118721B (fi) 2008-02-29
NZ291449A (en) 1998-09-24
FI970702A (fi) 1997-02-19
NO970553L (no) 1997-02-06
NO970553D0 (no) 1997-02-06
SK21997A3 (en) 1997-07-09
EP0776197A1 (de) 1997-06-04
CN1155836A (zh) 1997-07-30
PL319014A1 (en) 1997-07-21
JPH10504314A (ja) 1998-04-28
WO1996005815A1 (de) 1996-02-29
EP0776197B1 (de) 1998-11-11
MX9701301A (es) 1998-05-31
ZA956926B (en) 1996-03-25
IL114948A0 (en) 1995-12-08
CN1073413C (zh) 2001-10-24
DE4429664C2 (de) 1997-09-11
IL114948A (en) 2000-10-31
CA2197865C (en) 2005-10-25
FI970702A0 (fi) 1997-02-19
SK280299B6 (sk) 1999-11-08
CA2197865A1 (en) 1996-02-29
AU3258395A (en) 1996-03-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LTS LOHMANN THERAPIE-SYSTEME AG, 56626 ANDERNACH,