CA2197867A1 - Oestradiol transdermal therapeutic system comprising hygroscopic additives - Google Patents

Oestradiol transdermal therapeutic system comprising hygroscopic additives

Info

Publication number
CA2197867A1
CA2197867A1 CA002197867A CA2197867A CA2197867A1 CA 2197867 A1 CA2197867 A1 CA 2197867A1 CA 002197867 A CA002197867 A CA 002197867A CA 2197867 A CA2197867 A CA 2197867A CA 2197867 A1 CA2197867 A1 CA 2197867A1
Authority
CA
Canada
Prior art keywords
therapeutic system
transdermal therapeutic
oestradiol
hygroscopic additives
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002197867A
Other languages
French (fr)
Other versions
CA2197867C (en
Inventor
Walter Muller
Michael Horstmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4429667A external-priority patent/DE4429667C2/en
Application filed by Individual filed Critical Individual
Publication of CA2197867A1 publication Critical patent/CA2197867A1/en
Application granted granted Critical
Publication of CA2197867C publication Critical patent/CA2197867C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A transdermal therapeutic system comprising the active substance estradiol and having a layered structure of a backing layer which is impermeable to active substances and moisture, an active substance-containing matrix, and, if necessary, a removable protective layer covering the matrix, is characterized by the fact that the matrix comprises glycerol either comprising a maximum of 1%-wt.
of water or being substantially free from water.
CA002197867A 1994-08-20 1995-08-12 Oestradiol transdermal therapeutic system comprising hygroscopic additives Expired - Fee Related CA2197867C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP4429667.3 1994-08-20
DE4429667A DE4429667C2 (en) 1994-08-20 1994-08-20 Estradiol TTS with water-binding additives and process for its preparation
PCT/EP1995/003201 WO1996005814A1 (en) 1994-08-20 1995-08-12 Oestradiol transdermal therapeutic system comprising hygroscopic additives

Publications (2)

Publication Number Publication Date
CA2197867A1 true CA2197867A1 (en) 1996-02-29
CA2197867C CA2197867C (en) 2006-08-01

Family

ID=36764275

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002197867A Expired - Fee Related CA2197867C (en) 1994-08-20 1995-08-12 Oestradiol transdermal therapeutic system comprising hygroscopic additives

Country Status (1)

Country Link
CA (1) CA2197867C (en)

Also Published As

Publication number Publication date
CA2197867C (en) 2006-08-01

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130813