DK420985D0 - Fremgangsmaade til fremstilling af pregnanderivater - Google Patents

Fremgangsmaade til fremstilling af pregnanderivater

Info

Publication number
DK420985D0
DK420985D0 DK420985A DK420985A DK420985D0 DK 420985 D0 DK420985 D0 DK 420985D0 DK 420985 A DK420985 A DK 420985A DK 420985 A DK420985 A DK 420985A DK 420985 D0 DK420985 D0 DK 420985D0
Authority
DK
Denmark
Prior art keywords
derivatives
pregnant
procedure
preparation
hydrogen
Prior art date
Application number
DK420985A
Other languages
English (en)
Other versions
DK420985A (da
Inventor
Helmut Hofmeister
Klaus Annen
Henry Laurent
Rudolf Wiechert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK420985D0 publication Critical patent/DK420985D0/da
Publication of DK420985A publication Critical patent/DK420985A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Paper (AREA)
  • Sewage (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK420985A 1984-09-17 1985-09-17 Fremgangsmaade til fremstilling af pregnanderivater DK420985A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843434448 DE3434448A1 (de) 1984-09-17 1984-09-17 Verfahren zur herstellung von pregnan-derivaten

Publications (2)

Publication Number Publication Date
DK420985D0 true DK420985D0 (da) 1985-09-17
DK420985A DK420985A (da) 1986-03-18

Family

ID=6245838

Family Applications (1)

Application Number Title Priority Date Filing Date
DK420985A DK420985A (da) 1984-09-17 1985-09-17 Fremgangsmaade til fremstilling af pregnanderivater

Country Status (15)

Country Link
US (2) US4708823A (da)
EP (1) EP0181442B1 (da)
JP (1) JPH0710877B2 (da)
AT (1) ATE44532T1 (da)
CA (1) CA1260929A (da)
CS (1) CS250695B2 (da)
DD (1) DD238387A5 (da)
DE (2) DE3434448A1 (da)
DK (1) DK420985A (da)
ES (1) ES8604987A1 (da)
FI (1) FI853560L (da)
GR (1) GR852241B (da)
HU (1) HU194905B (da)
PL (1) PL255391A1 (da)
SU (1) SU1440351A3 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0523132A1 (en) * 1990-03-27 1993-01-20 Schering Corporation PROCESS FOR 9$g(a)-HYDROXY STEROID DEHYDRATION
AP141A (en) * 1990-04-25 1991-08-25 Richter Gedeon Vegyeszet Novel steroid doils.
WO1995030684A1 (en) * 1994-05-09 1995-11-16 Pharmacia & Upjohn Company SYNTHESIS OF 17β-CYANO-3-ETHOXY-17α-HYDROXY-6-METHYLANDROSTA-3,5,9(11)-TRIENE
JPH10191658A (ja) * 1996-01-09 1998-07-21 Nikon Corp 振動アクチュエータ
US5879711A (en) * 1997-11-07 1999-03-09 Sequeira; Joel A. Stable antiandrogenic gel composition
US6696592B2 (en) 2001-05-22 2004-02-24 Nicox-S.A. Methods of making 21-[4′-(nitrooxyalkyl)benzoate] corticosteroid derivatives and intermediates useful in the synthesis thereof
CN103833814A (zh) * 2014-03-06 2014-06-04 浙江仙居君业药业有限公司 17羟基-孕甾-4-烯-3,20-二酮-21-醋酸酯的制备方法
CN105017364A (zh) * 2015-07-06 2015-11-04 湖南新合新生物医药有限公司 甲基泼尼松龙中间体及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3067214A (en) * 1960-04-20 1962-12-04 Merck & Co Inc Haloethisterone compounds
DE2625306C2 (de) * 1976-06-02 1978-06-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Pregnan-Derivaten
HU185797B (en) * 1981-04-16 1985-03-28 Richter Gedeon Vegyeszet Process for producing 3-oxo-17-alpha-ethinyl-17beta-trifluoroacetoxy-gonane derivatives
EP0063368B1 (de) * 1981-04-16 1984-07-25 Richter Gedeon Vegyeszeti Gyar R.T. Verfahren zur Herstellung von Pregn-4-en-3,20-dionderivaten sowie 17-alpha-Äthinyl-17-beta-trifluoracetoxygon-4-en-3-onderivate und die letzteren enthaltende Arzneimittel
HU183397B (en) * 1981-04-16 1984-04-28 Richter Gedeon Vegyeszet Process for preparing 17alpha-hydroxy-pregn-4-ene-3,20-dione derivatives
US4342702A (en) * 1981-05-18 1982-08-03 The Upjohn Company Metallated halogenated acetylene corticoid synthesis
DE3315324A1 (de) * 1983-04-25 1984-10-31 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von 17(alpha)-(br oder j)-ethinyl-17ss-or-steroiden

Also Published As

Publication number Publication date
ATE44532T1 (de) 1989-07-15
EP0181442B1 (de) 1989-07-12
HUT38951A (en) 1986-07-28
HU194905B (en) 1988-03-28
JPS61129197A (ja) 1986-06-17
PL255391A1 (en) 1986-07-15
ES8604987A1 (es) 1986-03-16
DK420985A (da) 1986-03-18
ES546995A0 (es) 1986-03-16
JPH0710877B2 (ja) 1995-02-08
GR852241B (da) 1986-01-17
CS250695B2 (en) 1987-05-14
SU1440351A3 (ru) 1988-11-23
US4708823A (en) 1987-11-24
FI853560A0 (fi) 1985-09-17
US4956482A (en) 1990-09-11
DE3571441D1 (en) 1989-08-17
DE3434448A1 (de) 1986-03-27
DD238387A5 (de) 1986-08-20
EP0181442A1 (de) 1986-05-21
CA1260929A (en) 1989-09-26
FI853560L (fi) 1986-03-18

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment