GB991475A - Novel steroid compounds and processes for their production - Google Patents

Novel steroid compounds and processes for their production

Info

Publication number
GB991475A
GB991475A GB2953864A GB2953864A GB991475A GB 991475 A GB991475 A GB 991475A GB 2953864 A GB2953864 A GB 2953864A GB 2953864 A GB2953864 A GB 2953864A GB 991475 A GB991475 A GB 991475A
Authority
GB
United Kingdom
Prior art keywords
aroyloxy
ketal
acyloxy
group
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2953864A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of GB991475A publication Critical patent/GB991475A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Abstract

The invention comprises the 20-aroyloxy-5a -pregnane compounds of the general formula <FORM:0991475/C2/1> in which OR represents an aroyloxy group, R1 is a free or esterified hydroxy group, R2 is a hydroxy group or a 9(11) double bond, and R3 is the free or ketalized oxygen atom of a keto group, and processes for the preparation thereof by reducing a 7-ketal of a 20b -aroyloxy-3b -hydroxy - 5a - pregnane - 7,11 - dione of the general formula <FORM:0991475/C2/2> to form the corresponding 7-ketal of a 20b -aroyloxy - 3b ,11b - dihydroxy - 5a - pregnan-7-one, esterifying the latter to form the corresponding 3b -acyloxy or aryloxy compound, dehydrating the latter to obtain the corresponding 7-ketal of a 20b -aroyloxy-3b -acyloxy or aroyloxy - 5a - pregn - 9(11) - en - 7 - one and subjecting the latter to liberation at 7-position to obtain the corresponding 20b -aroyloxy - 3b - acyloxy or aroyloxy - 5a -pregn-9(11)-en-7-one. In the above reaction scheme reduction may be effected with potassium borohydride, esterification with benzoyl chloride, dehydration with methane sulphonyl chloride in pyridine and liberation of the 7-keto group with aqueous acid. Specification 991,474 also is referred to.
GB2953864A 1961-03-14 1962-03-14 Novel steroid compounds and processes for their production Expired GB991475A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR855565A FR1315722A (en) 1961-03-14 1961-03-14 New steroid derivatives and their preparation process

Publications (1)

Publication Number Publication Date
GB991475A true GB991475A (en) 1965-05-12

Family

ID=8750808

Family Applications (2)

Application Number Title Priority Date Filing Date
GB2953864A Expired GB991475A (en) 1961-03-14 1962-03-14 Novel steroid compounds and processes for their production
GB2953764A Expired GB991474A (en) 1961-03-14 1962-03-14 Novel steroid compounds and their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB2953764A Expired GB991474A (en) 1961-03-14 1962-03-14 Novel steroid compounds and their preparation

Country Status (2)

Country Link
FR (1) FR1315722A (en)
GB (2) GB991475A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2746704B1 (en) * 1996-03-29 1998-05-22 Fimor SCRAPING HEAD, ESPECIALLY FOR SCREEN PRINTING

Also Published As

Publication number Publication date
GB991474A (en) 1965-05-12
FR1315722A (en) 1963-01-25

Similar Documents

Publication Publication Date Title
GB991475A (en) Novel steroid compounds and processes for their production
GB1060793A (en) Improvements in or relating to steroids and the manufacture thereof
GB1103985A (en) Novel des-a-steroids
GB921534A (en) Cyclopentanophenanthrene derivatives and process for the production thereof
GB1001703A (en) 2-formyl-í¸-17ª‰-hydroxy-androstene compounds and process for their production
GB890577A (en) Pregnadienes and pregnatrienes
GB1015016A (en) New steroid compounds and processes
GB934802A (en) Steroid compounds
GB1000191A (en) New iminodibenzyl derivatives and processes for their production
GB1070762A (en) Enol esters and a process for their manufacture
GB737766A (en) Steroids
GB1082953A (en) Steroid derivatives
GB887814A (en) Steroids
GB922315A (en) New compounds useful in steroid synthesis and processes for the preparation thereof
GB896104A (en) Steroid compounds and their preparation
GB947000A (en) Process for the production of steroid compounds, and the new compounds thus produced
GB921156A (en) Synthesis of steroids
GB970484A (en) New 17-desoxy corticosteroids and processes for their preparation
GB748846A (en) A process for the manufacture of pregnan-3(-a)-ol-20-one and derivatives thereof
GB892170A (en) New a-nor-steroid compounds
GB852684A (en) 6-methyl steroid compounds
GB931785A (en) New steroid compounds, and processes for their preparation
GB876903A (en) New cyclopentanophenanthrene derivatives and process for the production thereof
ES282100A1 (en) Procedure for the preparation of new steroid compounds (Machine-translation by Google Translate, not legally binding)
GB1101791A (en) New 1ª‡:7ª‡-dimethyl steroids and a process for their manufacture