JPS5315360A - Preparation of pregnane compound 17 alpha-esters - Google Patents
Preparation of pregnane compound 17 alpha-estersInfo
- Publication number
- JPS5315360A JPS5315360A JP8819576A JP8819576A JPS5315360A JP S5315360 A JPS5315360 A JP S5315360A JP 8819576 A JP8819576 A JP 8819576A JP 8819576 A JP8819576 A JP 8819576A JP S5315360 A JPS5315360 A JP S5315360A
- Authority
- JP
- Japan
- Prior art keywords
- esters
- alpha
- preparation
- pregnane compound
- pregnane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AOSZTAHDEDLTLQ-AZKQZHLXSA-N (1S,2S,4R,8S,9S,11S,12R,13S,19S)-6-[(3-chlorophenyl)methyl]-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one Chemical compound C([C@@H]1C[C@H]2[C@H]3[C@]([C@]4(C=CC(=O)C=C4[C@@H](F)C3)C)(F)[C@@H](O)C[C@@]2([C@@]1(C1)C(=O)CO)C)N1CC1=CC=CC(Cl)=C1 AOSZTAHDEDLTLQ-AZKQZHLXSA-N 0.000 title 1
- JWMFYGXQPXQEEM-NUNROCCHSA-N 5β-pregnane Chemical compound C([C@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](CC)[C@@]2(C)CC1 JWMFYGXQPXQEEM-NUNROCCHSA-N 0.000 title 1
- 229940126657 Compound 17 Drugs 0.000 title 1
- -1 pregnane compound Chemical class 0.000 abstract 2
- 241000187654 Nocardia Species 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
PURPOSE: To prepare easily pregnane compound 18α-esters in high yield by acting Nocardia actiomycetes to pregnane compound 11β, 17α, 21-triesters or 11β, 17α-diesters.
COPYRIGHT: (C)1978,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51088195A JPS60994B2 (en) | 1976-07-26 | 1976-07-26 | Method for producing 17α-esters of pregnane compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51088195A JPS60994B2 (en) | 1976-07-26 | 1976-07-26 | Method for producing 17α-esters of pregnane compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5315360A true JPS5315360A (en) | 1978-02-13 |
JPS60994B2 JPS60994B2 (en) | 1985-01-11 |
Family
ID=13936107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51088195A Expired JPS60994B2 (en) | 1976-07-26 | 1976-07-26 | Method for producing 17α-esters of pregnane compounds |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS60994B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014533275A (en) * | 2011-11-11 | 2014-12-11 | アラーガン インコーポレイテッドAllergan,Incorporated | Pharmaceutical composition and method of use of 4-pregenen-11β-17-21-triol-3,20-dione derivative |
-
1976
- 1976-07-26 JP JP51088195A patent/JPS60994B2/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014533275A (en) * | 2011-11-11 | 2014-12-11 | アラーガン インコーポレイテッドAllergan,Incorporated | Pharmaceutical composition and method of use of 4-pregenen-11β-17-21-triol-3,20-dione derivative |
US10188667B2 (en) | 2011-11-11 | 2019-01-29 | Allergan, Inc. | Pharmaceutical compositions and methods of use of 4-pregenen-11β-17-21-triol-3,20-dione derivatives |
US10493082B2 (en) | 2011-11-11 | 2019-12-03 | Allergan, Inc. | 4-pregenen-11β-17-21-triol-3,20-dione derivatives |
Also Published As
Publication number | Publication date |
---|---|
JPS60994B2 (en) | 1985-01-11 |
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