ATE119905T1 - Makrolide antibiotika und verfahren zu deren herstellung. - Google Patents

Makrolide antibiotika und verfahren zu deren herstellung.

Info

Publication number
ATE119905T1
ATE119905T1 AT86307059T AT86307059T ATE119905T1 AT E119905 T1 ATE119905 T1 AT E119905T1 AT 86307059 T AT86307059 T AT 86307059T AT 86307059 T AT86307059 T AT 86307059T AT E119905 T1 ATE119905 T1 AT E119905T1
Authority
AT
Austria
Prior art keywords
production
sup
compounds
hydroxyl group
macrolid antibiotics
Prior art date
Application number
AT86307059T
Other languages
English (en)
Inventor
John B Ward
Hazel M Noble
Neil Porter
Richard A Fletton
David Noble
Derek R Sutherland
Michael V J Ramsay
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858522692A external-priority patent/GB8522692D0/en
Priority claimed from GB858522695A external-priority patent/GB8522695D0/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ATE119905T1 publication Critical patent/ATE119905T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT86307059T 1985-09-13 1986-09-12 Makrolide antibiotika und verfahren zu deren herstellung. ATE119905T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858522692A GB8522692D0 (en) 1985-09-13 1985-09-13 Chemical compounds
GB858522695A GB8522695D0 (en) 1985-09-13 1985-09-13 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE119905T1 true ATE119905T1 (de) 1995-04-15

Family

ID=26289765

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86307059T ATE119905T1 (de) 1985-09-13 1986-09-12 Makrolide antibiotika und verfahren zu deren herstellung.

Country Status (10)

Country Link
US (1) US4950683A (de)
EP (1) EP0215654B1 (de)
JP (1) JPH085893B2 (de)
AT (1) ATE119905T1 (de)
AU (1) AU598204B2 (de)
CA (1) CA1316915C (de)
DE (1) DE3650265T2 (de)
FI (1) FI100025B (de)
IE (1) IE67373B1 (de)
NZ (1) NZ217567A (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
JPH0774219B2 (ja) * 1986-01-23 1995-08-09 アメリカン・サイアナミツド・カンパニー マクロライド抗生物質
GB8606116D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
US5019589A (en) * 1986-09-12 1991-05-28 American Cyanamid Company Δ23 -LL-F28249 compounds
ATE82017T1 (de) * 1986-09-12 1992-11-15 American Cyanamid Co 23-deoxy-derivate von ll-f28249-verbindungen.
US5149832A (en) * 1986-09-12 1992-09-22 American Cyanamid Company Mono and diacyl derivatives of ll-f28249 compounds
US4886828A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
EP0259779B1 (de) * 1986-09-12 1994-08-10 American Cyanamid Company 23-Oxo(keto) und 23-Imino-Derivate von LL-F28249-Verbindungen
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US5525506A (en) * 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
US5238848A (en) * 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4886830A (en) * 1987-03-06 1989-12-12 American Cyanamid Company Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds
US4956479A (en) * 1987-03-06 1990-09-11 American Cyanamid Company 23-deoxy-27-chloro derivatives of LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
JPS6431776A (en) * 1987-07-28 1989-02-02 Sankyo Co Novel macrolide compound and production thereof
US5240850A (en) * 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
PT88952B (pt) * 1987-11-09 1993-02-26 Pfizer Processo para a preparacao de avermectinas etiladas
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
US4895837A (en) * 1988-01-29 1990-01-23 Merck & Co., Inc. Avermectin derivatives
US4918097A (en) * 1988-03-11 1990-04-17 Ciba-Geigy Corporation Insecticides and parasiticides
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
GB8813760D0 (en) * 1988-06-10 1988-07-13 American Cyanamid Co Chemical process
CA2052860A1 (en) * 1990-10-11 1992-04-12 Thomas L. Shih Avermectin degradation products and derivatives
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
CZ287404B6 (en) * 1993-10-05 2000-11-15 Pfizer Process for preparing doramectin
US8080705B2 (en) 2004-07-28 2011-12-20 The Procter & Gamble Company Superabsorbent polymers comprising direct covalent bonds between polymer chain segments and method of making them
US20060128827A1 (en) * 2004-12-10 2006-06-15 The Procter & Gamble Company Absorbent members comprising modified water absorbent resin for use in diapers
EP1669394A1 (de) * 2004-12-10 2006-06-14 The Procter & Gamble Company Superabsorbierende Polymerpartikel mit verbesserter Oberflächenvernetzung und hydrophiler Eigenschaft und Verfahren zur Herstellung
JP2007077366A (ja) * 2005-09-16 2007-03-29 Procter & Gamble Co 吸水剤の製法
WO2007120561A2 (en) * 2006-04-10 2007-10-25 The Procter & Gamble Company An absorbent member comprising a modified water absorbent resin
WO2008102322A2 (en) * 2007-02-22 2008-08-28 The Procter & Gamble Company Method of surface treating particulate material using electromagnetic radiation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US32034A (en) * 1861-04-09 Langdon sawyer
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
USRE32034E (en) 1977-12-19 1985-11-19 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
US4328335A (en) * 1979-08-13 1982-05-04 Merck & Co., Inc. Process for the interconversion of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
JPS5916894A (ja) * 1982-07-21 1984-01-28 Sankyo Co Ltd ミルベマイシンｄの５−アシルオキシ誘導体
JPS5920284A (ja) * 1982-07-23 1984-02-01 Sankyo Co Ltd ミルベマイシンｄの５−エ−テル誘導体及びその塩
DE3519834C2 (de) * 1984-06-05 1993-12-16 American Cyanamid Co Neue antibiotische Wirkstoffe, Verfahren zu ihrer Gewinnung und ihre Anwendung zur Bekämpfung von Infektionen bei Tieren und Pflanzen
GR852232B (de) * 1984-09-14 1986-01-14 American Cyanamid Co
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina

Also Published As

Publication number Publication date
AU6263486A (en) 1987-03-19
CA1316915C (en) 1993-04-27
JPS6267087A (ja) 1987-03-26
US4950683A (en) 1990-08-21
IE67373B1 (en) 1996-03-20
EP0215654A2 (de) 1987-03-25
DE3650265D1 (de) 1995-04-20
JPH085893B2 (ja) 1996-01-24
NZ217567A (en) 1988-07-28
FI100025B (fi) 1997-08-29
DE3650265T2 (de) 1995-07-27
EP0215654B1 (de) 1995-03-15
AU598204B2 (en) 1990-06-21
IE862443L (en) 1987-03-13
FI864150A0 (fi) 1986-10-14
EP0215654A3 (en) 1987-07-22
FI864150A7 (fi) 1988-04-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee