DK374985A - Fremgangsmaade til fremstilling af (4s)-6-flour-spiro-(chroman-4,4'-imidazolidin)-2',5'-dion eller (2r)-methylderivatet deraf og mellemprodukter til anvendelse ved fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af (4s)-6-flour-spiro-(chroman-4,4'-imidazolidin)-2',5'-dion eller (2r)-methylderivatet deraf og mellemprodukter til anvendelse ved fremgangsmaaden Download PDF

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Publication number
DK374985A
DK374985A DK374985A DK374985A DK374985A DK 374985 A DK374985 A DK 374985A DK 374985 A DK374985 A DK 374985A DK 374985 A DK374985 A DK 374985A DK 374985 A DK374985 A DK 374985A
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Prior art keywords
spiro
methyl
derivative
compound
acid
Prior art date
Application number
DK374985A
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Danish (da)
English (en)
Other versions
DK374985D0 (da
Inventor
Frank John Urban
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK374985D0 publication Critical patent/DK374985D0/da
Publication of DK374985A publication Critical patent/DK374985A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Pens And Brushes (AREA)
  • Coloring (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Indole Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Cosmetics (AREA)
DK374985A 1984-08-20 1985-08-19 Fremgangsmaade til fremstilling af (4s)-6-flour-spiro-(chroman-4,4'-imidazolidin)-2',5'-dion eller (2r)-methylderivatet deraf og mellemprodukter til anvendelse ved fremgangsmaaden DK374985A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64200884A 1984-08-20 1984-08-20

Publications (2)

Publication Number Publication Date
DK374985D0 DK374985D0 (da) 1985-08-19
DK374985A true DK374985A (da) 1986-02-21

Family

ID=24574782

Family Applications (1)

Application Number Title Priority Date Filing Date
DK374985A DK374985A (da) 1984-08-20 1985-08-19 Fremgangsmaade til fremstilling af (4s)-6-flour-spiro-(chroman-4,4'-imidazolidin)-2',5'-dion eller (2r)-methylderivatet deraf og mellemprodukter til anvendelse ved fremgangsmaaden

Country Status (22)

Country Link
US (1) US4716113A (ja)
EP (1) EP0172719B1 (ja)
JP (2) JPS6157588A (ja)
KR (1) KR870000628B1 (ja)
AT (1) ATE37371T1 (ja)
AU (1) AU556793B2 (ja)
DD (2) DD240207A5 (ja)
DE (1) DE3565105D1 (ja)
DK (1) DK374985A (ja)
EG (1) EG17060A (ja)
ES (1) ES8700259A1 (ja)
FI (1) FI853183L (ja)
GR (1) GR851993B (ja)
HU (3) HU201042B (ja)
IL (1) IL76131A (ja)
NO (1) NO853254L (ja)
NZ (1) NZ213128A (ja)
PH (1) PH26782A (ja)
PL (2) PL148572B1 (ja)
PT (1) PT80985B (ja)
YU (1) YU43879B (ja)
ZA (1) ZA856267B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952694A (en) * 1988-07-27 1990-08-28 Pfizer Inc. Novel resolution process for racemic spiro-hydantoins
US5006657A (en) * 1988-07-27 1991-04-09 Pfizer Inc. Intermediates in a resolution process for racemic spiro hydantoins
US5151544A (en) * 1990-05-25 1992-09-29 Alcon Laboratories, Inc. Intermediates in the preparation of chiral spirofluorenehydantoins
US5206367A (en) * 1992-02-18 1993-04-27 Pfizer Inc. Preparation of optically active spiro-hydantoins
US5508466A (en) * 1994-04-13 1996-04-16 G.D. Searle & Co. Synthesis of N-protected-α-substituted-glycine racemic esters by zinc-mediated addition of organic halide to glycine cation equivalent
JP6273251B2 (ja) * 2013-02-12 2018-01-31 国立大学法人大阪大学 芳香族アミノ酸誘導体およびそれを用いるｐｅｔプローブ

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3878043A (en) * 1973-01-02 1975-04-15 Univ Southern Illinois Method for preparing L-dopa and novels compounds useful therein
DE2336718A1 (de) * 1973-07-19 1975-02-06 Basf Ag Verfahren zur herstellung von substituierten oxazolinon-(5)-verbindungen
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
DE2807286A1 (de) * 1978-02-21 1979-08-23 Bayer Ag Stereoselektive spaltung von phenylglycinderivaten und 4-hydroxyphenylglycinderivaten mit enzymharzen
US4267342A (en) * 1978-08-21 1981-05-12 Pfizer Inc. Spiro-oxazolidindiones
US4262092A (en) * 1979-05-08 1981-04-14 Ethyl Corporation Process for producing N-acyl-D-phenylalanine ester
DE2927534A1 (de) * 1979-07-07 1981-01-08 Bayer Ag Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung
DE2927535A1 (de) * 1979-07-07 1981-01-08 Bayer Ag Stereoselektive spaltung von phenylglycinderivaten mit enzymharzen
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
GB2098212B (en) * 1981-05-12 1984-11-14 Ici Plc Process for preparing 1'-substituted-spiro(imidazolidine)-4,3'-indoline-2,2',5-triones
US4435578A (en) * 1982-11-10 1984-03-06 Pfizer Inc. Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
US4474967A (en) * 1983-04-27 1984-10-02 Pfizer Inc. 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione
US4464380A (en) * 1983-05-25 1984-08-07 Pfizer Inc. Imidazolidinedione derivatives

Also Published As

Publication number Publication date
ES8700259A1 (es) 1986-10-01
JPS6362512B2 (ja) 1988-12-02
EP0172719A1 (en) 1986-02-26
PL260564A1 (en) 1987-02-09
AU4641485A (en) 1986-02-27
KR870002142A (ko) 1987-03-30
EP0172719B1 (en) 1988-09-21
IL76131A (en) 1989-01-31
HU194857B (en) 1988-03-28
DK374985D0 (da) 1985-08-19
PH26782A (en) 1992-10-13
HUT39745A (en) 1986-10-29
HUT43577A (en) 1987-11-30
PL147253B1 (en) 1989-05-31
NO853254L (no) 1986-02-21
JPS6157588A (ja) 1986-03-24
PL148572B1 (en) 1989-10-31
IL76131A0 (en) 1985-12-31
GR851993B (ja) 1985-12-17
HU193127B (en) 1987-08-28
US4716113A (en) 1987-12-29
DD254005A5 (de) 1988-02-10
KR870000628B1 (ko) 1987-03-26
AU556793B2 (en) 1986-11-20
ES546294A0 (es) 1986-10-01
PL255065A1 (en) 1986-11-04
YU43879B (en) 1989-12-31
JPS63290873A (ja) 1988-11-28
PT80985B (pt) 1987-12-30
FI853183L (fi) 1986-02-21
DE3565105D1 (en) 1988-10-27
DD240207A5 (de) 1986-10-22
HU201042B (en) 1990-09-28
YU131985A (en) 1988-04-30
ZA856267B (en) 1987-04-29
NZ213128A (en) 1988-02-29
ATE37371T1 (de) 1988-10-15
HUT46316A (en) 1988-10-28
FI853183A0 (fi) 1985-08-19
PT80985A (en) 1985-09-01
EG17060A (en) 1991-03-30

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Legal Events

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