DK3524609T3 - Fremgangsmåde til fremstilling af 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromenderivater, optiske isomerer deraf og mellemprodukter fra processen - Google Patents

Fremgangsmåde til fremstilling af 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromenderivater, optiske isomerer deraf og mellemprodukter fra processen Download PDF

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Publication number
DK3524609T3
DK3524609T3 DK17858666.5T DK17858666T DK3524609T3 DK 3524609 T3 DK3524609 T3 DK 3524609T3 DK 17858666 T DK17858666 T DK 17858666T DK 3524609 T3 DK3524609 T3 DK 3524609T3
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DK
Denmark
Prior art keywords
chromener
hexahydropyrano
phenyl
derivatives
procedure
Prior art date
Application number
DK17858666.5T
Other languages
English (en)
Inventor
Sang Ku Yoo
Jin Wook Chung
In Geun Jo
Ji Young Kim
Jeong Ho Im
Ku Suk Kang
Jin Young Kim
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Glaceum Inc
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Publication of DK3524609T3 publication Critical patent/DK3524609T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK17858666.5T 2016-10-04 2017-09-27 Fremgangsmåde til fremstilling af 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromenderivater, optiske isomerer deraf og mellemprodukter fra processen DK3524609T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160127805 2016-10-04
PCT/KR2017/010679 WO2018066872A1 (ko) 2016-10-04 2017-09-27 3-페닐-2,3,4,8,9,10-헥사히드로피라노[2,3-f]크로멘 유도체 및 이의 광학 이성질체 합성 방법

Publications (1)

Publication Number Publication Date
DK3524609T3 true DK3524609T3 (da) 2021-07-26

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK17858666.5T DK3524609T3 (da) 2016-10-04 2017-09-27 Fremgangsmåde til fremstilling af 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromenderivater, optiske isomerer deraf og mellemprodukter fra processen

Country Status (19)

Country Link
US (2) US10669282B2 (da)
EP (1) EP3524609B1 (da)
JP (1) JP6810275B2 (da)
KR (2) KR20180037584A (da)
CN (1) CN109863152B (da)
AR (1) AR109735A1 (da)
AU (1) AU2017338514B2 (da)
BR (1) BR112019006736A8 (da)
CA (1) CA3039326C (da)
DK (1) DK3524609T3 (da)
ES (1) ES2881000T3 (da)
HU (1) HUE055701T2 (da)
IL (1) IL265706B (da)
MX (1) MX2019003818A (da)
PL (1) PL3524609T3 (da)
PT (1) PT3524609T (da)
TW (1) TWI641610B (da)
WO (1) WO2018066872A1 (da)
ZA (1) ZA201902760B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201811796SA (en) 2016-06-29 2019-02-27 Glaceum Inc Optically active pyranochromenyl phenol derivative and pharmaceutical composition comprising same
KR20180037584A (ko) * 2016-10-04 2018-04-12 주식회사 글라세움 3-페닐-2,3,4,8,9,10-헥사히드로피라노[2,3-f]크로멘 유도체 및 이의 광학 이성질체 합성 방법
TWI804600B (zh) * 2018-04-03 2023-06-11 南韓商格雷森伍股份有限公司 3-苯基-2,8-二氫吡喃[2,3-ƒ]苯并哌喃衍生物的合成方法
WO2020071818A1 (ko) * 2018-10-02 2020-04-09 주식회사 글라세움 탄소 이중결합 함유 화합물의 비대칭 수소첨가 반응용 촉매
KR20200038182A (ko) 2018-10-02 2020-04-10 주식회사 글라세움 탄소 이중결합 함유 화합물의 비대칭 수소첨가 반응용 촉매
KR20200105198A (ko) * 2019-02-28 2020-09-07 주식회사 글라세움 신경계 질환의 예방 또는 치료용 약학적 조성물
KR20210014521A (ko) 2019-07-30 2021-02-09 주식회사 글라세움 2-((6-(히드록시메틸)크로멘-5-일)옥시)-1-페닐에타논 유도체의 합성 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100565423B1 (ko) * 2003-10-20 2006-03-30 빅 바이오 주식회사 이소플라반 유도체 또는 이소플라벤 유도체의 제조방법
JP2006008604A (ja) * 2004-06-25 2006-01-12 Kuraray Co Ltd イソフラバン誘導体の製造方法
WO2007058480A1 (en) * 2005-11-16 2007-05-24 Md Bioalpha Co., Ltd. Composition having effect on treatment and prevention of diseases syndrome treatment with glabridin
US8563599B2 (en) * 2008-03-03 2013-10-22 The United States Of America, Represented By The Secretary Of Agriculture Methods for synthesizing glycinols, glyceollins I and II, compositions of selected intermediates, and therapeutic uses thereof
CN101555259B (zh) * 2009-05-15 2012-06-27 中国科学院上海有机化学研究所 螺环骨架膦噁唑啉配体、合成方法及其在不对称氢化反应中的应用
CN103030647B (zh) 2013-01-16 2014-10-29 山东省分析测试中心 一种光甘草定的合成方法
KR102344479B1 (ko) * 2013-12-24 2021-12-29 주식회사 글라세움 피라노크로메닐페놀 유도체, 및 대사증후군 또는 염증 질환 치료용 약학 조성물
SG11201811796SA (en) * 2016-06-29 2019-02-27 Glaceum Inc Optically active pyranochromenyl phenol derivative and pharmaceutical composition comprising same
KR20180037584A (ko) * 2016-10-04 2018-04-12 주식회사 글라세움 3-페닐-2,3,4,8,9,10-헥사히드로피라노[2,3-f]크로멘 유도체 및 이의 광학 이성질체 합성 방법

Also Published As

Publication number Publication date
IL265706A (en) 2019-05-30
CA3039326A1 (en) 2018-04-12
MX2019003818A (es) 2019-08-12
TWI641610B (zh) 2018-11-21
ES2881000T3 (es) 2021-11-26
TW201813970A (zh) 2018-04-16
US20200048272A1 (en) 2020-02-13
PL3524609T3 (pl) 2021-12-27
AU2017338514A1 (en) 2019-05-23
BR112019006736A8 (pt) 2022-08-23
PT3524609T (pt) 2021-07-15
KR20180037584A (ko) 2018-04-12
BR112019006736A2 (da) 2019-07-23
KR20180091803A (ko) 2018-08-16
CA3039326C (en) 2022-09-20
US20200199142A1 (en) 2020-06-25
IL265706B (en) 2021-06-30
CN109863152A (zh) 2019-06-07
KR101893393B1 (ko) 2018-08-30
AU2017338514B2 (en) 2020-05-14
EP3524609A1 (en) 2019-08-14
JP6810275B2 (ja) 2021-01-06
US10669282B2 (en) 2020-06-02
HUE055701T2 (hu) 2021-12-28
AR109735A1 (es) 2019-01-16
NZ753171A (en) 2021-05-28
WO2018066872A1 (ko) 2018-04-12
US10947250B2 (en) 2021-03-16
EP3524609A4 (en) 2020-04-08
JP2019529577A (ja) 2019-10-17
ZA201902760B (en) 2021-09-29
EP3524609B1 (en) 2021-05-26
CN109863152B (zh) 2021-12-03

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