DK3176164T3 - Optisk isomer af 1,4-benzothiazepin-1-oxidderivat og farmaceutisk sammensætning fremstillet ved anvendelse deraf - Google Patents
Optisk isomer af 1,4-benzothiazepin-1-oxidderivat og farmaceutisk sammensætning fremstillet ved anvendelse deraf Download PDFInfo
- Publication number
- DK3176164T3 DK3176164T3 DK15826775T DK15826775T DK3176164T3 DK 3176164 T3 DK3176164 T3 DK 3176164T3 DK 15826775 T DK15826775 T DK 15826775T DK 15826775 T DK15826775 T DK 15826775T DK 3176164 T3 DK3176164 T3 DK 3176164T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzothiazepine
- pharmaceutical composition
- composition prepared
- optical isomer
- oxide derivative
- Prior art date
Links
- TUPGNPRENOAMPM-UHFFFAOYSA-N 1$l^{4},4-benzothiazepine 1-oxide Chemical class O=S1C=CN=CC2=CC=CC=C12 TUPGNPRENOAMPM-UHFFFAOYSA-N 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014155068 | 2014-07-30 | ||
PCT/JP2015/070488 WO2016017448A1 (ja) | 2014-07-30 | 2015-07-17 | 1,4-ベンゾチアゼピン-1-オキシド誘導体の光学異性体、及びそれを用いた医薬組成物 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3176164T3 true DK3176164T3 (da) | 2019-10-28 |
Family
ID=55217353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15826775T DK3176164T3 (da) | 2014-07-30 | 2015-07-17 | Optisk isomer af 1,4-benzothiazepin-1-oxidderivat og farmaceutisk sammensætning fremstillet ved anvendelse deraf |
Country Status (12)
Country | Link |
---|---|
US (1) | US10071996B2 (da) |
EP (1) | EP3176164B1 (da) |
JP (1) | JP6574773B2 (da) |
KR (1) | KR102091211B1 (da) |
CN (1) | CN106795148B (da) |
AU (1) | AU2015297705B2 (da) |
CA (1) | CA2956699C (da) |
DK (1) | DK3176164T3 (da) |
ES (1) | ES2750580T3 (da) |
PL (1) | PL3176164T3 (da) |
TW (1) | TWI572603B (da) |
WO (1) | WO2016017448A1 (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116042742A (zh) * | 2016-06-27 | 2023-05-02 | 葛兰素史克知识产权第二有限公司 | 合成方法 |
EP3725315B1 (en) * | 2017-12-11 | 2023-10-04 | Aetas Pharma Co. Ltd. | Renal dysfunction improving drug comprising optical isomer of 1,4-benzothiazepine-1-oxide derivative |
JPWO2021015221A1 (da) | 2019-07-22 | 2021-01-28 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS488825Y1 (da) | 1970-06-12 | 1973-03-08 | ||
GB9009389D0 (en) | 1990-04-26 | 1990-06-20 | Smith Kline French Lab | Treatment |
JP2703408B2 (ja) | 1990-12-28 | 1998-01-26 | 麒麟麦酒株式会社 | 1,4‐ベンゾチアゼピン誘導体 |
HRP960232A2 (en) | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
JP4064027B2 (ja) | 1998-12-28 | 2008-03-19 | 金子 昇 | 心房細動治療薬 |
WO2000038688A1 (fr) | 1998-12-28 | 2000-07-06 | Japan Tobacco Inc. | Compositions medicamenteuses utilisees dans le traitement de la fibrillation auriculaire |
JP4041642B2 (ja) | 1999-05-19 | 2008-01-30 | 昇 金子 | 制癌剤耐性克服剤および制癌剤効果増強剤 |
KR100686617B1 (ko) | 1999-05-19 | 2007-02-23 | 가네꼬 노보루 | 1,4-벤조티아제핀유도체의 항암제 내성극복의약조성물 |
CN100413539C (zh) | 2000-08-07 | 2008-08-27 | 葛兰素史密斯克莱实验室公司 | 5-ht4受体拮抗剂在制备治疗电生理心房改型的药物中的应用 |
JP2003095977A (ja) | 2001-09-21 | 2003-04-03 | Masafumi Yano | 筋肉収縮・弛緩機能障害関連疾患の治療又は予防剤 |
JP4603534B2 (ja) | 2004-04-28 | 2010-12-22 | 株式会社アエタスファルマ | 左室拡張障害の治療薬 |
WO2007053610A2 (en) | 2005-11-01 | 2007-05-10 | The Regents Of The University Of California | Methods of treating atrial fibrillation wtih pirfenidone |
BRPI0621832A2 (pt) | 2006-07-05 | 2013-03-19 | Lupin Ltd | processo para a preparaÇço de enantiâmeros oticamente puros ou oticamente enriquecidos de compostos de sulfàxido |
AU2010219044B2 (en) | 2009-02-25 | 2012-10-04 | Noboru Kaneko | 1,4-benzothiazepine-1-oxide derivative and pharmaceutical composition utilizing the same |
WO2010114562A1 (en) | 2009-04-03 | 2010-10-07 | Sequel Pharmaceuticals, Inc. | Improved methods of administration of k201 (jtv-519) (4-[3-{1-(4-benzyl) piperidinyl}propionyl]-7-methoxy 2, 3, 4, 5-tetrahydro-1, 4-benzothiazepine monohydrochloride) |
FR2963790B1 (fr) | 2010-08-11 | 2012-09-28 | Pf Medicament | Docosahexaeneoate de panthenyle et son utilisation dans le traitement et la prevention des maladies cardiovasculaires |
JP2012184225A (ja) | 2011-02-18 | 2012-09-27 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
EP2708535A1 (en) | 2012-05-11 | 2014-03-19 | Les Laboratoires Servier | Agents for treating disorders involving modulation of ryanodine receptors |
-
2015
- 2015-07-17 PL PL15826775T patent/PL3176164T3/pl unknown
- 2015-07-17 EP EP15826775.7A patent/EP3176164B1/en active Active
- 2015-07-17 ES ES15826775T patent/ES2750580T3/es active Active
- 2015-07-17 CA CA2956699A patent/CA2956699C/en active Active
- 2015-07-17 AU AU2015297705A patent/AU2015297705B2/en active Active
- 2015-07-17 US US15/329,827 patent/US10071996B2/en active Active
- 2015-07-17 CN CN201580040674.7A patent/CN106795148B/zh active Active
- 2015-07-17 WO PCT/JP2015/070488 patent/WO2016017448A1/ja active Application Filing
- 2015-07-17 KR KR1020177003192A patent/KR102091211B1/ko active IP Right Grant
- 2015-07-17 JP JP2016538270A patent/JP6574773B2/ja active Active
- 2015-07-17 DK DK15826775T patent/DK3176164T3/da active
- 2015-07-23 TW TW104123852A patent/TWI572603B/zh active
Also Published As
Publication number | Publication date |
---|---|
EP3176164B1 (en) | 2019-08-21 |
EP3176164A4 (en) | 2018-01-03 |
KR20170031712A (ko) | 2017-03-21 |
JPWO2016017448A1 (ja) | 2017-05-18 |
AU2015297705B2 (en) | 2019-12-19 |
AU2015297705A1 (en) | 2017-03-02 |
US10071996B2 (en) | 2018-09-11 |
PL3176164T3 (pl) | 2020-05-18 |
CN106795148B (zh) | 2019-12-10 |
TWI572603B (zh) | 2017-03-01 |
CA2956699C (en) | 2020-09-29 |
US20170247362A1 (en) | 2017-08-31 |
JP6574773B2 (ja) | 2019-09-11 |
KR102091211B1 (ko) | 2020-03-19 |
CN106795148A (zh) | 2017-05-31 |
CA2956699A1 (en) | 2016-02-04 |
TW201607945A (zh) | 2016-03-01 |
EP3176164A1 (en) | 2017-06-07 |
WO2016017448A1 (ja) | 2016-02-04 |
ES2750580T3 (es) | 2020-03-26 |
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