PL3176164T3 - Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciem - Google Patents
Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciemInfo
- Publication number
- PL3176164T3 PL3176164T3 PL15826775T PL15826775T PL3176164T3 PL 3176164 T3 PL3176164 T3 PL 3176164T3 PL 15826775 T PL15826775 T PL 15826775T PL 15826775 T PL15826775 T PL 15826775T PL 3176164 T3 PL3176164 T3 PL 3176164T3
- Authority
- PL
- Poland
- Prior art keywords
- benzothiazepine
- pharmaceutical composition
- same
- composition prepared
- optical isomer
- Prior art date
Links
- TUPGNPRENOAMPM-UHFFFAOYSA-N 1$l^{4},4-benzothiazepine 1-oxide Chemical class O=S1C=CN=CC2=CC=CC=C12 TUPGNPRENOAMPM-UHFFFAOYSA-N 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014155068 | 2014-07-30 | ||
| PCT/JP2015/070488 WO2016017448A1 (ja) | 2014-07-30 | 2015-07-17 | １，４－ベンゾチアゼピン－１－オキシド誘導体の光学異性体、及びそれを用いた医薬組成物 |
| EP15826775.7A EP3176164B1 (en) | 2014-07-30 | 2015-07-17 | Optical isomer of 1,4-benzothiazepine-1-oxide derivative, and pharmaceutical composition prepared using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3176164T3 true PL3176164T3 (pl) | 2020-05-18 |
Family
ID=55217353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15826775T PL3176164T3 (pl) | 2014-07-30 | 2015-07-17 | Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciem |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10071996B2 (pl) |
| EP (1) | EP3176164B1 (pl) |
| JP (1) | JP6574773B2 (pl) |
| KR (1) | KR102091211B1 (pl) |
| CN (1) | CN106795148B (pl) |
| AU (1) | AU2015297705B2 (pl) |
| CA (1) | CA2956699C (pl) |
| DK (1) | DK3176164T3 (pl) |
| ES (1) | ES2750580T3 (pl) |
| PL (1) | PL3176164T3 (pl) |
| TW (1) | TWI572603B (pl) |
| WO (1) | WO2016017448A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018002827A1 (en) * | 2016-06-27 | 2018-01-04 | Glaxosmithkline Intellectual Property (No.2) Limited | Synthetic methods |
| TWI741240B (zh) * | 2017-12-11 | 2021-10-01 | 日商埃塔斯製藥股份有限公司 | 含有1,4-苯并硫氮呯-1-氧化物衍生物之光學異構物之腎功能障礙的改善藥 |
| TWI827866B (zh) * | 2019-07-22 | 2024-01-01 | 日商埃塔斯製藥股份有限公司 | 有光學活性的1,4-苯並硫氮呯-1-氧化物衍生物的製造方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS488825Y1 (pl) | 1970-06-12 | 1973-03-08 | ||
| GB9009389D0 (en) | 1990-04-26 | 1990-06-20 | Smith Kline French Lab | Treatment |
| JP2703408B2 (ja) | 1990-12-28 | 1998-01-26 | 麒麟麦酒株式会社 | １，４‐ベンゾチアゼピン誘導体 |
| HRP960232A2 (en) | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
| JP4064027B2 (ja) | 1998-12-28 | 2008-03-19 | 金子 昇 | 心房細動治療薬 |
| DE69929362T2 (de) | 1998-12-28 | 2006-09-28 | Kaneko, Noboru | verwendung von 1,4-benzothiazepinen zur Herstellung eines Medikaments ZUR BEHANDLUNG DER VORHOF-FIBRILLATION |
| KR100686617B1 (ko) | 1999-05-19 | 2007-02-23 | 가네꼬 노보루 | 1,4-벤조티아제핀유도체의 항암제 내성극복의약조성물 |
| JP4041642B2 (ja) | 1999-05-19 | 2008-01-30 | 昇 金子 | 制癌剤耐性克服剤および制癌剤効果増強剤 |
| PL365048A1 (pl) | 2000-08-07 | 2004-12-27 | Laboratoire Glaxosmithkline S.A.S. | Zastosowanie agonistów receptora 5HT4 w profilaktyce lub leczeniu niektórych zaburzeń sercowo-naczyniowych |
| JP2003095977A (ja) | 2001-09-21 | 2003-04-03 | Masafumi Yano | 筋肉収縮・弛緩機能障害関連疾患の治療又は予防剤 |
| AU2005238389B2 (en) | 2004-04-28 | 2009-08-06 | Aetas Pharma Co., Ltd. | Muscle relaxation accelerator and therapeutic agent for muscular tissue diseases such as muscle relaxation failure |
| WO2007053610A2 (en) | 2005-11-01 | 2007-05-10 | The Regents Of The University Of California | Methods of treating atrial fibrillation wtih pirfenidone |
| BRPI0621832A2 (pt) * | 2006-07-05 | 2013-03-19 | Lupin Ltd | processo para a preparaÇço de enantiâmeros oticamente puros ou oticamente enriquecidos de compostos de sulfàxido |
| JP4808825B2 (ja) | 2009-02-25 | 2011-11-02 | 昇 金子 | １，４−ベンゾチアゼピン−１−オキシド誘導体、及びそれを用いた医薬組成物 |
| WO2010114562A1 (en) * | 2009-04-03 | 2010-10-07 | Sequel Pharmaceuticals, Inc. | Improved methods of administration of k201 (jtv-519) (4-[3-{1-(4-benzyl) piperidinyl}propionyl]-7-methoxy 2, 3, 4, 5-tetrahydro-1, 4-benzothiazepine monohydrochloride) |
| FR2963790B1 (fr) | 2010-08-11 | 2012-09-28 | Pf Medicament | Docosahexaeneoate de panthenyle et son utilisation dans le traitement et la prevention des maladies cardiovasculaires |
| JP2012184225A (ja) | 2011-02-18 | 2012-09-27 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
| EP2708535A1 (en) | 2012-05-11 | 2014-03-19 | Les Laboratoires Servier | Agents for treating disorders involving modulation of ryanodine receptors |
-
2015
- 2015-07-17 AU AU2015297705A patent/AU2015297705B2/en active Active
- 2015-07-17 WO PCT/JP2015/070488 patent/WO2016017448A1/ja active Application Filing
- 2015-07-17 KR KR1020177003192A patent/KR102091211B1/ko active IP Right Grant
- 2015-07-17 CA CA2956699A patent/CA2956699C/en active Active
- 2015-07-17 JP JP2016538270A patent/JP6574773B2/ja active Active
- 2015-07-17 DK DK15826775T patent/DK3176164T3/da active
- 2015-07-17 PL PL15826775T patent/PL3176164T3/pl unknown
- 2015-07-17 US US15/329,827 patent/US10071996B2/en active Active
- 2015-07-17 CN CN201580040674.7A patent/CN106795148B/zh active Active
- 2015-07-17 ES ES15826775T patent/ES2750580T3/es active Active
- 2015-07-17 EP EP15826775.7A patent/EP3176164B1/en active Active
- 2015-07-23 TW TW104123852A patent/TWI572603B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20170031712A (ko) | 2017-03-21 |
| AU2015297705A1 (en) | 2017-03-02 |
| JP6574773B2 (ja) | 2019-09-11 |
| CA2956699C (en) | 2020-09-29 |
| EP3176164B1 (en) | 2019-08-21 |
| ES2750580T3 (es) | 2020-03-26 |
| KR102091211B1 (ko) | 2020-03-19 |
| US20170247362A1 (en) | 2017-08-31 |
| WO2016017448A1 (ja) | 2016-02-04 |
| EP3176164A1 (en) | 2017-06-07 |
| TW201607945A (zh) | 2016-03-01 |
| CA2956699A1 (en) | 2016-02-04 |
| CN106795148B (zh) | 2019-12-10 |
| AU2015297705B2 (en) | 2019-12-19 |
| CN106795148A (zh) | 2017-05-31 |
| DK3176164T3 (da) | 2019-10-28 |
| JPWO2016017448A1 (ja) | 2017-05-18 |
| US10071996B2 (en) | 2018-09-11 |
| EP3176164A4 (en) | 2018-01-03 |
| TWI572603B (zh) | 2017-03-01 |
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