PL3524609T3 - Sposób wytwarzania pochodnych 3-fenylo-2,3,4,8,9,10-heksahydropirano[2,3-f]chromenu i ich izomerów optycznych oraz związków pośrednich sposobu - Google Patents

Sposób wytwarzania pochodnych 3-fenylo-2,3,4,8,9,10-heksahydropirano[2,3-f]chromenu i ich izomerów optycznych oraz związków pośrednich sposobu

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Publication number
PL3524609T3
PL3524609T3 PL17858666T PL17858666T PL3524609T3 PL 3524609 T3 PL3524609 T3 PL 3524609T3 PL 17858666 T PL17858666 T PL 17858666T PL 17858666 T PL17858666 T PL 17858666T PL 3524609 T3 PL3524609 T3 PL 3524609T3
Authority
PL
Poland
Prior art keywords
hexahydropyrano
intermediates
phenyl
preparation
optical isomers
Prior art date
Application number
PL17858666T
Other languages
English (en)
Inventor
Sang Ku Yoo
Jin Wook Chung
In Geun Jo
Ji Young Kim
Jeong Ho Im
Ku Suk Kang
Jin Young Kim
Original Assignee
Glaceum, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaceum, Inc. filed Critical Glaceum, Inc.
Publication of PL3524609T3 publication Critical patent/PL3524609T3/pl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
PL17858666T 2016-10-04 2017-09-27 Sposób wytwarzania pochodnych 3-fenylo-2,3,4,8,9,10-heksahydropirano[2,3-f]chromenu i ich izomerów optycznych oraz związków pośrednich sposobu PL3524609T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20160127805 2016-10-04
PCT/KR2017/010679 WO2018066872A1 (ko) 2016-10-04 2017-09-27 3-페닐-2,3,4,8,9,10-헥사히드로피라노[2,3-f]크로멘 유도체 및 이의 광학 이성질체 합성 방법
EP17858666.5A EP3524609B1 (en) 2016-10-04 2017-09-27 Process for the preparation of 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivatives, optical isomers thereof, and intermediates of the process

Publications (1)

Publication Number Publication Date
PL3524609T3 true PL3524609T3 (pl) 2021-12-27

Family

ID=61831886

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17858666T PL3524609T3 (pl) 2016-10-04 2017-09-27 Sposób wytwarzania pochodnych 3-fenylo-2,3,4,8,9,10-heksahydropirano[2,3-f]chromenu i ich izomerów optycznych oraz związków pośrednich sposobu

Country Status (19)

Country Link
US (2) US10669282B2 (pl)
EP (1) EP3524609B1 (pl)
JP (1) JP6810275B2 (pl)
KR (2) KR20180037584A (pl)
CN (1) CN109863152B (pl)
AR (1) AR109735A1 (pl)
AU (1) AU2017338514B2 (pl)
BR (1) BR112019006736A8 (pl)
CA (1) CA3039326C (pl)
DK (1) DK3524609T3 (pl)
ES (1) ES2881000T3 (pl)
HU (1) HUE055701T2 (pl)
IL (1) IL265706B (pl)
MX (1) MX2019003818A (pl)
PL (1) PL3524609T3 (pl)
PT (1) PT3524609T (pl)
TW (1) TWI641610B (pl)
WO (1) WO2018066872A1 (pl)
ZA (1) ZA201902760B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109476676B (zh) 2016-06-29 2021-09-17 格拉斯如睦株式会社 旋光性吡喃并色烯基苯酚衍生物及包含其的药物组合物
PL3524609T3 (pl) * 2016-10-04 2021-12-27 Glaceum, Inc. Sposób wytwarzania pochodnych 3-fenylo-2,3,4,8,9,10-heksahydropirano[2,3-f]chromenu i ich izomerów optycznych oraz związków pośrednich sposobu
TWI804600B (zh) * 2018-04-03 2023-06-11 南韓商格雷森伍股份有限公司 3-苯基-2,8-二氫吡喃[2,3-ƒ]苯并哌喃衍生物的合成方法
WO2020071818A1 (ko) * 2018-10-02 2020-04-09 주식회사 글라세움 탄소 이중결합 함유 화합물의 비대칭 수소첨가 반응용 촉매
KR20200038182A (ko) * 2018-10-02 2020-04-10 주식회사 글라세움 탄소 이중결합 함유 화합물의 비대칭 수소첨가 반응용 촉매
KR20200105198A (ko) * 2019-02-28 2020-09-07 주식회사 글라세움 신경계 질환의 예방 또는 치료용 약학적 조성물
KR20210014521A (ko) 2019-07-30 2021-02-09 주식회사 글라세움 2-((6-(히드록시메틸)크로멘-5-일)옥시)-1-페닐에타논 유도체의 합성 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100565423B1 (ko) 2003-10-20 2006-03-30 빅 바이오 주식회사 이소플라반 유도체 또는 이소플라벤 유도체의 제조방법
JP2006008604A (ja) * 2004-06-25 2006-01-12 Kuraray Co Ltd イソフラバン誘導体の製造方法
WO2007058480A1 (en) * 2005-11-16 2007-05-24 Md Bioalpha Co., Ltd. Composition having effect on treatment and prevention of diseases syndrome treatment with glabridin
US8563599B2 (en) * 2008-03-03 2013-10-22 The United States Of America, Represented By The Secretary Of Agriculture Methods for synthesizing glycinols, glyceollins I and II, compositions of selected intermediates, and therapeutic uses thereof
CN101555259B (zh) * 2009-05-15 2012-06-27 中国科学院上海有机化学研究所 螺环骨架膦噁唑啉配体、合成方法及其在不对称氢化反应中的应用
CN103030647B (zh) * 2013-01-16 2014-10-29 山东省分析测试中心 一种光甘草定的合成方法
KR102344479B1 (ko) 2013-12-24 2021-12-29 주식회사 글라세움 피라노크로메닐페놀 유도체, 및 대사증후군 또는 염증 질환 치료용 약학 조성물
CN109476676B (zh) 2016-06-29 2021-09-17 格拉斯如睦株式会社 旋光性吡喃并色烯基苯酚衍生物及包含其的药物组合物
PL3524609T3 (pl) * 2016-10-04 2021-12-27 Glaceum, Inc. Sposób wytwarzania pochodnych 3-fenylo-2,3,4,8,9,10-heksahydropirano[2,3-f]chromenu i ich izomerów optycznych oraz związków pośrednich sposobu

Also Published As

Publication number Publication date
BR112019006736A8 (pt) 2022-08-23
CN109863152B (zh) 2021-12-03
US10947250B2 (en) 2021-03-16
CN109863152A (zh) 2019-06-07
CA3039326C (en) 2022-09-20
AR109735A1 (es) 2019-01-16
IL265706B (en) 2021-06-30
TWI641610B (zh) 2018-11-21
EP3524609A1 (en) 2019-08-14
KR101893393B1 (ko) 2018-08-30
US20200199142A1 (en) 2020-06-25
EP3524609A4 (en) 2020-04-08
DK3524609T3 (da) 2021-07-26
BR112019006736A2 (pl) 2019-07-23
NZ753171A (en) 2021-05-28
US10669282B2 (en) 2020-06-02
JP6810275B2 (ja) 2021-01-06
KR20180037584A (ko) 2018-04-12
IL265706A (en) 2019-05-30
EP3524609B1 (en) 2021-05-26
ES2881000T3 (es) 2021-11-26
AU2017338514A1 (en) 2019-05-23
AU2017338514B2 (en) 2020-05-14
WO2018066872A1 (ko) 2018-04-12
ZA201902760B (en) 2021-09-29
JP2019529577A (ja) 2019-10-17
PT3524609T (pt) 2021-07-15
KR20180091803A (ko) 2018-08-16
TW201813970A (zh) 2018-04-16
US20200048272A1 (en) 2020-02-13
MX2019003818A (es) 2019-08-12
HUE055701T2 (hu) 2021-12-28
CA3039326A1 (en) 2018-04-12

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