DK3255141T3 - Fremstilling af antistoffer med forbedret glycosyleringsmønster - Google Patents

Fremstilling af antistoffer med forbedret glycosyleringsmønster Download PDF

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Publication number
DK3255141T3
DK3255141T3 DK17179340.9T DK17179340T DK3255141T3 DK 3255141 T3 DK3255141 T3 DK 3255141T3 DK 17179340 T DK17179340 T DK 17179340T DK 3255141 T3 DK3255141 T3 DK 3255141T3
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DK
Denmark
Prior art keywords
antibodies
preparation
glycosylation pattern
improved glycosylation
improved
Prior art date
Application number
DK17179340.9T
Other languages
English (en)
Inventor
Daniel R Lasko
Stephan M Koza
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38645762&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3255141(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
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Publication of DK3255141T3 publication Critical patent/DK3255141T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK17179340.9T 2006-07-13 2007-07-11 Fremstilling af antistoffer med forbedret glycosyleringsmønster DK3255141T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83065806P 2006-07-13 2006-07-13
EP12164058.5A EP2495307B9 (en) 2006-07-13 2007-07-11 Production of coagulation factor IX with improved glycosylation pattern

Publications (1)

Publication Number Publication Date
DK3255141T3 true DK3255141T3 (da) 2022-01-31

Family

ID=38645762

Family Applications (3)

Application Number Title Priority Date Filing Date
DK17179340.9T DK3255141T3 (da) 2006-07-13 2007-07-11 Fremstilling af antistoffer med forbedret glycosyleringsmønster
DK07796784T DK2041270T3 (da) 2006-07-13 2007-07-11 Fremstilling af glycoproteiner
DK12164058.5T DK2495307T5 (da) 2006-07-13 2007-07-11 Fremstilling af koagulationsfaktor IX med forbedret glycosyleringsmønster

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK07796784T DK2041270T3 (da) 2006-07-13 2007-07-11 Fremstilling af glycoproteiner
DK12164058.5T DK2495307T5 (da) 2006-07-13 2007-07-11 Fremstilling af koagulationsfaktor IX med forbedret glycosyleringsmønster

Country Status (23)

Country Link
US (1) US8129145B2 (da)
EP (3) EP2495307B9 (da)
JP (1) JP5401310B2 (da)
KR (1) KR101495549B1 (da)
CN (2) CN101541950A (da)
AR (1) AR061976A1 (da)
AU (1) AU2007272957B2 (da)
BR (1) BRPI0714212B8 (da)
CA (1) CA2657248C (da)
DK (3) DK3255141T3 (da)
ES (2) ES2668212T3 (da)
HK (1) HK1214307A1 (da)
HU (1) HUE039128T2 (da)
IL (1) IL196252A (da)
MX (1) MX2009000349A (da)
PE (1) PE20081194A1 (da)
PL (2) PL2041270T3 (da)
PT (2) PT2495307T (da)
RU (1) RU2463345C2 (da)
SI (1) SI2495307T1 (da)
TR (1) TR201807021T4 (da)
TW (1) TW200812577A (da)
WO (1) WO2008008360A1 (da)

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Also Published As

Publication number Publication date
KR20090029841A (ko) 2009-03-23
US20080081356A1 (en) 2008-04-03
TR201807021T4 (tr) 2018-06-21
IL196252A0 (en) 2011-08-01
EP2041270B1 (en) 2013-11-20
AU2007272957A1 (en) 2008-01-17
EP2495307B1 (en) 2018-02-21
KR101495549B1 (ko) 2015-02-25
ES2668212T9 (es) 2018-05-30
CA2657248A1 (en) 2008-01-17
EP3255141B1 (en) 2021-12-01
CN101541950A (zh) 2009-09-23
DK2495307T3 (da) 2018-05-07
RU2463345C2 (ru) 2012-10-10
CN104878064A (zh) 2015-09-02
BRPI0714212B8 (pt) 2021-05-25
ES2440487T3 (es) 2014-01-29
RU2008152449A (ru) 2010-08-20
PT2041270E (pt) 2013-12-27
PT2495307T (pt) 2018-05-10
IL196252A (en) 2016-02-29
DK2495307T5 (da) 2018-07-16
EP2041270A1 (en) 2009-04-01
TW200812577A (en) 2008-03-16
EP3255141A1 (en) 2017-12-13
JP5401310B2 (ja) 2014-01-29
EP2495307B9 (en) 2018-05-02
US8129145B2 (en) 2012-03-06
EP2495307A1 (en) 2012-09-05
DK2041270T3 (da) 2014-01-27
CA2657248C (en) 2018-10-30
AU2007272957B2 (en) 2014-05-01
JP2009543550A (ja) 2009-12-10
HUE039128T2 (hu) 2018-12-28
HK1214307A1 (zh) 2016-07-22
SI2495307T1 (en) 2018-05-31
MX2009000349A (es) 2009-03-09
AR061976A1 (es) 2008-08-10
PE20081194A1 (es) 2008-09-22
PL2495307T3 (pl) 2018-07-31
ES2668212T3 (es) 2018-05-17
BRPI0714212A2 (pt) 2013-03-26
BRPI0714212B1 (pt) 2021-01-19
PL2041270T3 (pl) 2014-04-30
WO2008008360A1 (en) 2008-01-17

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