DK3222280T3 - Forøgelse af lægemiddelbiotilgængelighed i naltrexonbehandling - Google Patents

Forøgelse af lægemiddelbiotilgængelighed i naltrexonbehandling Download PDF

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Publication number
DK3222280T3
DK3222280T3 DK17156985.8T DK17156985T DK3222280T3 DK 3222280 T3 DK3222280 T3 DK 3222280T3 DK 17156985 T DK17156985 T DK 17156985T DK 3222280 T3 DK3222280 T3 DK 3222280T3
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DK
Denmark
Prior art keywords
increase
bio availability
naltrexone treatment
drug bio
drug
Prior art date
Application number
DK17156985.8T
Other languages
Danish (da)
English (en)
Inventor
Shawn Flanagan
Eduardo Dunayevich
Original Assignee
Nalpropion Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46172304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3222280(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nalpropion Pharmaceuticals Llc filed Critical Nalpropion Pharmaceuticals Llc
Application granted granted Critical
Publication of DK3222280T3 publication Critical patent/DK3222280T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acoustics & Sound (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Physics & Mathematics (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
DK17156985.8T 2010-12-03 2011-12-02 Forøgelse af lægemiddelbiotilgængelighed i naltrexonbehandling DK3222280T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41939510P 2010-12-03 2010-12-03
EP11845186.3A EP2646031B9 (en) 2010-12-03 2011-12-02 Increasing drug bioavailability in naltrexone therapy

Publications (1)

Publication Number Publication Date
DK3222280T3 true DK3222280T3 (da) 2021-04-19

Family

ID=46172304

Family Applications (4)

Application Number Title Priority Date Filing Date
DK17156985.8T DK3222280T3 (da) 2010-12-03 2011-12-02 Forøgelse af lægemiddelbiotilgængelighed i naltrexonbehandling
DK23209711.3T DK4349369T3 (da) 2010-12-03 2011-12-02 Forøgelse af biotilgængelighed af lægemiddel i naltrexonbehandling
DK11845186.3T DK2646031T3 (en) 2010-12-03 2011-12-02 Increased drug bioavailability in naltrexone therapy
DK21152314.7T DK3884947T3 (da) 2010-12-03 2011-12-02 Forøgelse af lægemiddelbiotilgængelighed i naltrexonterapi

Family Applications After (3)

Application Number Title Priority Date Filing Date
DK23209711.3T DK4349369T3 (da) 2010-12-03 2011-12-02 Forøgelse af biotilgængelighed af lægemiddel i naltrexonbehandling
DK11845186.3T DK2646031T3 (en) 2010-12-03 2011-12-02 Increased drug bioavailability in naltrexone therapy
DK21152314.7T DK3884947T3 (da) 2010-12-03 2011-12-02 Forøgelse af lægemiddelbiotilgængelighed i naltrexonterapi

Country Status (27)

Country Link
US (1) US20130245056A1 (https=)
EP (5) EP4696322A3 (https=)
JP (5) JP6008866B2 (https=)
KR (5) KR20140035320A (https=)
CN (1) CN103313711A (https=)
AR (2) AR093182A1 (https=)
AU (2) AU2011336304B2 (https=)
BR (1) BR112013013390A2 (https=)
CA (2) CA2819262C (https=)
CL (1) CL2013001564A1 (https=)
CY (2) CY1118968T1 (https=)
DK (4) DK3222280T3 (https=)
ES (3) ES2866879T3 (https=)
FI (2) FI3884947T3 (https=)
HR (4) HRP20251576T1 (https=)
HU (3) HUE053831T2 (https=)
IL (3) IL226504B (https=)
LT (4) LT4349369T (https=)
MX (2) MX356801B (https=)
PL (4) PL3884947T3 (https=)
PT (4) PT3884947T (https=)
RS (4) RS56014B1 (https=)
RU (1) RU2640561C2 (https=)
SI (4) SI3222280T1 (https=)
SM (4) SMT201700232T1 (https=)
TW (1) TWI618536B (https=)
WO (1) WO2012075459A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE034290T2 (en) 2003-04-29 2018-02-28 Orexigen Therapeutics Inc Preparations containing opioid antagonist and bupropion to affect weight loss
CA2630624C (en) 2005-11-22 2013-08-06 Orexigen Therapeutics, Inc. Compositions and methods for increasing insulin sensitivity
WO2007089318A2 (en) * 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions and methods for reducing food cravings
JP2011521973A (ja) 2008-05-30 2011-07-28 オレキシジェン・セラピューティクス・インコーポレーテッド 内臓脂肪の状態を処置するための方法
ES2762113T3 (es) 2010-01-11 2020-05-22 Nalpropion Pharmaceuticals Inc Métodos de proporcionar terapia de pérdida de peso en pacientes con depresión mayor
SMT201700232T1 (it) * 2010-12-03 2017-07-18 Orexigen Therapeutics Inc Aumento della biodisponibilita' farmacologica nella terapia con naltrexone
LT3730132T (lt) 2012-06-06 2022-08-25 Nalpropion Pharmaceuticals Llc Kompozicija, skirta panaudoti pacientų su didele širdies ir kraujagyslių ligų rizika antsvorio ir nutukimo gydymo būde
US20180015042A1 (en) * 2015-02-07 2018-01-18 Intas Pharmaceuticals Ltd. Pharmaceutical composition for the treatment of obesity
WO2018178690A1 (en) * 2017-03-28 2018-10-04 LDN Pharma Limited An agent that increases the expression of the bcl2-associated agonist of cell death for the treatment of cancer
EP3482751A1 (en) 2017-11-14 2019-05-15 LDN Pharma Limited Cancer treatment
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10129265A1 (de) * 2001-06-18 2003-01-02 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
US6972291B2 (en) * 2002-07-02 2005-12-06 Bernstein Richard K Method for reducing food intake
EP1772147A2 (en) * 2003-03-17 2007-04-11 Japan Tobacco, Inc. Method for increasing the oral bioavailability of S-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]-2-methylpropanethioate
HUE034290T2 (en) 2003-04-29 2018-02-28 Orexigen Therapeutics Inc Preparations containing opioid antagonist and bupropion to affect weight loss
US20070117827A1 (en) 2005-07-27 2007-05-24 Gary Tollefson Compositions for affecting weight loss
US8921344B2 (en) * 2006-11-03 2014-12-30 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
CA2630624C (en) 2005-11-22 2013-08-06 Orexigen Therapeutics, Inc. Compositions and methods for increasing insulin sensitivity
WO2007089318A2 (en) 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions and methods for reducing food cravings
JP2009517393A (ja) 2005-11-28 2009-04-30 オレキシジェン・セラピューティクス・インコーポレーテッド 不安症の治療方法
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
SI2719378T1 (sl) * 2006-06-19 2016-11-30 Alpharma Pharmaceuticals Llc Farmacevtski sestavki
KR101264789B1 (ko) 2006-06-30 2013-05-15 엘지디스플레이 주식회사 횡전계 방식 액정표시장치용 어레이 기판과 그 제조방법
CA2693992C (en) * 2006-07-20 2017-01-31 Somaxon Pharmaceuticals, Inc. Methods of improving the pharmacokinetics of doxepin
TWI609702B (zh) * 2006-11-09 2018-01-01 歐瑞根治療有限公司 層狀醫藥調配物
KR20170077291A (ko) 2006-11-09 2017-07-05 오렉시젠 세러퓨틱스 인크. 단위 용량 팩키지
LT2545939T (lt) * 2007-04-11 2021-03-10 Biomarin Pharmaceutical Inc. Tetrahidrobiopterinas, skirtas gydyti ligas, susijusias supadidėjusiu fenilalanino kiekiu
DE102007036076A1 (de) 2007-08-01 2009-02-05 Bayer Healthcare Aktiengesellschaft Dipeptoid-Produgs und ihre Verwendung
US8318813B2 (en) * 2007-09-13 2012-11-27 Lcs Group, Llc Method of treating binge eating disorder
JP2011521973A (ja) 2008-05-30 2011-07-28 オレキシジェン・セラピューティクス・インコーポレーテッド 内臓脂肪の状態を処置するための方法
SMT201700232T1 (it) 2010-12-03 2017-07-18 Orexigen Therapeutics Inc Aumento della biodisponibilita' farmacologica nella terapia con naltrexone

Also Published As

Publication number Publication date
CA3239386A1 (en) 2012-06-07
ES3056642T3 (en) 2026-02-23
JP2019056004A (ja) 2019-04-11
AR093182A1 (es) 2015-05-27
KR101984500B1 (ko) 2019-05-31
AU2011336304A1 (en) 2013-07-11
HUE034393T2 (en) 2018-02-28
MX2013006071A (es) 2013-10-01
TW201304780A (zh) 2013-02-01
RS65198B1 (sr) 2024-03-29
EP2646031A4 (en) 2014-04-23
KR20200044158A (ko) 2020-04-28
EP4349369A2 (en) 2024-04-10
EP4696322A2 (en) 2026-02-18
EP4349369B1 (en) 2025-09-17
RU2640561C2 (ru) 2018-01-09
HRP20240115T1 (hr) 2024-06-07
JP2013544290A (ja) 2013-12-12
SMT202400038T1 (it) 2024-03-13
EP3884947B1 (en) 2023-11-15
IL226504B (en) 2021-01-31
RS67527B1 (sr) 2026-01-30
LT3884947T (lt) 2024-03-12
RU2017144631A (ru) 2019-02-18
TWI618536B (zh) 2018-03-21
SMT202500474T1 (it) 2026-01-12
HUE053831T2 (hu) 2021-07-28
HUE065852T2 (hu) 2024-06-28
AU2011336304B2 (en) 2017-03-30
CY1124331T1 (el) 2022-07-22
RS62149B1 (sr) 2021-08-31
DK4349369T3 (da) 2025-12-22
PL3884947T3 (pl) 2024-05-06
RU2017144631A3 (https=) 2021-04-13
AU2017204309A1 (en) 2017-07-13
PL3222280T3 (pl) 2021-11-29
ES2866879T3 (es) 2021-10-20
FI3884947T3 (fi) 2024-01-30
EP4349369A3 (en) 2024-05-15
KR20180069089A (ko) 2018-06-22
SI3222280T1 (sl) 2021-11-30
MX356801B (es) 2018-06-13
JP7025319B2 (ja) 2022-02-24
CY1118968T1 (el) 2018-01-10
KR102105857B1 (ko) 2020-05-04
BR112013013390A2 (pt) 2016-09-06
CA2819262A1 (en) 2012-06-07
CA2819262C (en) 2024-05-28
RU2013127423A (ru) 2015-01-10
DK2646031T3 (en) 2017-05-22
AR124500A2 (es) 2023-04-05
MX384662B (es) 2025-03-14
SI2646031T1 (sl) 2017-07-31
WO2012075459A1 (en) 2012-06-07
PT3222280T (pt) 2021-04-22
DK3884947T3 (da) 2024-01-22
EP2646031B1 (en) 2017-02-22
LT4349369T (lt) 2026-01-12
EP2646031B9 (en) 2018-01-10
JP2024071605A (ja) 2024-05-24
ES2625527T9 (es) 2018-09-25
EP2646031A1 (en) 2013-10-09
EP4696322A3 (en) 2026-04-15
CN103313711A (zh) 2013-09-18
PL2646031T3 (pl) 2017-08-31
RS56014B1 (sr) 2017-09-29
KR20140035320A (ko) 2014-03-21
IL279626A (en) 2021-03-01
EP3222280A1 (en) 2017-09-27
US20130245056A1 (en) 2013-09-19
PT2646031T (pt) 2017-05-25
KR20210063473A (ko) 2021-06-01
HRP20210618T1 (hr) 2021-09-17
HRP20170734T1 (hr) 2017-08-11
ES2625527T3 (es) 2017-07-19
JP2022060331A (ja) 2022-04-14
EP3884947A1 (en) 2021-09-29
LT3222280T (lt) 2021-05-10
PT4349369T (pt) 2025-12-17
FI4349369T3 (fi) 2025-12-17
IL270841A (en) 2020-01-30
SI3884947T1 (sl) 2024-06-28
SMT201700232T1 (it) 2017-07-18
PT3884947T (pt) 2024-02-16
JP6008866B2 (ja) 2016-10-19
JP6456890B2 (ja) 2019-01-23
EP3222280B1 (en) 2021-01-20
HRP20251576T1 (hr) 2026-01-30
KR102258043B1 (ko) 2021-05-28
KR102391511B1 (ko) 2022-04-26
JP2016210809A (ja) 2016-12-15
SI4349369T1 (sl) 2026-02-27
KR20190058702A (ko) 2019-05-29
LT2646031T (lt) 2017-06-26
SMT202100227T1 (it) 2021-07-12
CL2013001564A1 (es) 2014-05-02
PL4349369T3 (pl) 2026-03-23

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