PL2544682T3 - Fitokannabinoidy w leczeniu glejaka - Google Patents

Fitokannabinoidy w leczeniu glejaka

Info

Publication number
PL2544682T3
PL2544682T3 PL11709175T PL11709175T PL2544682T3 PL 2544682 T3 PL2544682 T3 PL 2544682T3 PL 11709175 T PL11709175 T PL 11709175T PL 11709175 T PL11709175 T PL 11709175T PL 2544682 T3 PL2544682 T3 PL 2544682T3
Authority
PL
Poland
Prior art keywords
phytocannabinoids
glioblastoma
treatment
Prior art date
Application number
PL11709175T
Other languages
English (en)
Inventor
Daniela Parolaro
Paola Massi
Angelo Antonio Izzo
Francesca Borelli
Gabriella Aviello
Marzo Vincenzo Di
Petrocellis Luciano De
Aniello Schiano Moriello
Alessia Ligresti
Ruth Alexandra Ross
Lesley Ann Ford
Sharon Anavi-Goffer
Manuel Guzman
Guillermo Velasco
Mar Lorente
Sofia Torres
Tetsuro Kikuchi
Geoffrey Guy
Colin Stott
Stephen Wright
Alan Sutton
David Potter
Meijer Etienne De
Original Assignee
Gw Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42261478&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2544682(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gw Pharma Ltd filed Critical Gw Pharma Ltd
Publication of PL2544682T3 publication Critical patent/PL2544682T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/348Cannabaceae
    • A61K36/3482Cannabis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL11709175T 2010-03-12 2011-03-11 Fitokannabinoidy w leczeniu glejaka PL2544682T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1004137.4A GB2478595B (en) 2010-03-12 2010-03-12 Phytocannabinoids in the treatment of glioma
PCT/GB2011/050487 WO2011110866A1 (en) 2010-03-12 2011-03-11 Phytocannabinoids in the treatment of cancer
EP11709175.1A EP2544682B1 (en) 2010-03-12 2011-03-11 Phytocannabinoids in the treatment of cancer

Publications (1)

Publication Number Publication Date
PL2544682T3 true PL2544682T3 (pl) 2016-08-31

Family

ID=42261478

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11709175T PL2544682T3 (pl) 2010-03-12 2011-03-11 Fitokannabinoidy w leczeniu glejaka

Country Status (28)

Country Link
US (3) US8790719B2 (pl)
EP (1) EP2544682B1 (pl)
JP (1) JP5785569B2 (pl)
KR (1) KR20130067248A (pl)
CN (1) CN102869356A (pl)
AR (1) AR080454A1 (pl)
AU (3) AU2011225837A1 (pl)
BR (1) BR112012023017A8 (pl)
CA (1) CA2792722A1 (pl)
CO (1) CO6630103A2 (pl)
CY (1) CY1117451T1 (pl)
DK (1) DK2544682T3 (pl)
EA (1) EA201290901A1 (pl)
ES (1) ES2569669T3 (pl)
GB (1) GB2478595B (pl)
HR (1) HRP20160427T1 (pl)
HU (1) HUE029817T2 (pl)
IL (1) IL221871A (pl)
MX (1) MX2012010512A (pl)
NZ (2) NZ629136A (pl)
PH (1) PH12012501782A1 (pl)
PL (1) PL2544682T3 (pl)
SG (1) SG184016A1 (pl)
SI (1) SI2544682T1 (pl)
TW (1) TWI461205B (pl)
UA (1) UA109271C2 (pl)
WO (1) WO2011110866A1 (pl)
ZA (1) ZA201207574B (pl)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2377218A (en) * 2001-05-04 2003-01-08 Gw Pharmaceuticals Ltd Process and apparatus for extraction of active substances and enriched extracts from natural products
KR20070089151A (ko) 2004-11-16 2007-08-30 지더블유 파마 리미티드 카나비노이드의 새로운 용도
GB0425248D0 (en) 2004-11-16 2004-12-15 Gw Pharma Ltd New use for cannabinoid
GB2460672B (en) * 2008-06-04 2012-01-04 Gw Pharma Ltd Cannabinoids in combination with non-cannabinoid chemotherapeutic agents that are alkylating agents
GB2471523A (en) 2009-07-03 2011-01-05 Gw Pharma Ltd Use of tetrahydrocannibivarin (THCV) and optionally cannabidiol (CBD) in the treatment of epilepsy
GB2478595B (en) 2010-03-12 2018-04-04 Gw Pharma Ltd Phytocannabinoids in the treatment of glioma
TWI583374B (zh) 2010-03-30 2017-05-21 Gw伐瑪有限公司 使用植物大麻素次大麻二酚(cbdv)來治療癲癇之用途
GB2487712B (en) 2011-01-04 2015-10-28 Otsuka Pharma Co Ltd Use of the phytocannabinoid cannabidiol (CBD) in combination with a standard anti-epileptic drug (SAED) in the treatment of epilepsy
GB2494461A (en) * 2011-09-12 2013-03-13 Gw Pharma Ltd Phytocannabinoids for use in the treatment of invasive cancers or metastases
GB2514054A (en) * 2011-09-29 2014-11-12 Gw Pharma Ltd A pharmaceutical composition comprising the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD)
GB201117956D0 (en) * 2011-10-18 2011-11-30 Otsuka Pharma Co Ltd Phytocannabinoids for use in the treatment of breast cancer
US9776014B2 (en) 2012-05-03 2017-10-03 Magdent Ltd. Bone enhancement device and method
CA2895805A1 (en) * 2012-12-18 2014-06-26 Kotzker Consulting Llc Use of cannabinoids and terpenes for treatment of organophosphate and carbamate toxicity
CA3012383C (en) 2013-02-28 2021-03-02 Teewinot Technologies Limited Biosynthesis of cannabinoids
EP2968259B1 (en) 2013-03-14 2022-09-14 SC Laboratories Inc. Bioactive concentrates and uses thereof
US9095554B2 (en) 2013-03-15 2015-08-04 Biotech Institute LLC Breeding, production, processing and use of specialty cannabis
US10441617B2 (en) 2013-03-15 2019-10-15 Biotech Institute, Llc Breeding, production, processing and use of medical cannabis
GB2513167B (en) * 2013-04-18 2016-03-02 Otsuka Pharma Co Ltd Tetrahydrocannabivarin for use in the treatment of nausea and vomiting
GB2515312A (en) * 2013-06-19 2014-12-24 Gw Pharma Ltd The use of phytocannabinoids in the treatment of ovarian carcinoma
GB2516814B (en) * 2013-06-19 2016-08-31 Otsuka Pharma Co Ltd Use of phytocannabinoids for increasing radiosensitivity in the treatment of cancer
US10774288B2 (en) * 2013-09-18 2020-09-15 The Werc Shop, LLC Terpene-based compositions, processes, methodologies for creation and products thereby
AU2014347807A1 (en) * 2013-10-31 2016-05-26 Full Spectrum Laboratories, Ltd. Terpene and cannabinoid formulations
GB2530001B (en) 2014-06-17 2019-01-16 Gw Pharma Ltd Use of cannabidiol in the reduction of convulsive seizure frequency in treatment-resistant epilepsy
GB2527599A (en) 2014-06-27 2015-12-30 Gw Pharma Ltd Use of 7-OH-Cannabidiol (7-OH-CBD) and/or 7-OH-Cannabidivarin (7-OH-CBDV) in the treatment of epilepsy
GB2527590A (en) * 2014-06-27 2015-12-30 Otsuka Pharma Co Ltd Active pharmaceutical ingredient (API) comprising cannabinoids for use in the treatment of cancer
AU2015292915B2 (en) 2014-07-21 2020-10-15 Pharmaceutical Productions, Inc. Solid dosage form composition for buccal or sublingual administration of cannabinoids
JP6622793B2 (ja) 2014-08-25 2019-12-18 ティーウィノット テクノロジーズ リミテッド カンナビノイド化合物を同時作製する装置及び方法
CA2961410C (en) 2014-09-16 2023-07-11 India Globalization Capital, Inc. Cannabinoid composition and method for treating pain
WO2016054268A1 (en) 2014-09-30 2016-04-07 MJAR Holdings, LLC Methods of growing cannabaceae plants using artificial lighting
GB2531278A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabidiol in the treatment of intractable epilepsy
GB2531281A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabidiol in the treatment of intractable epilepsy
GB2531282A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabinoids in the treatment of epilepsy
CN107205960A (zh) * 2014-10-21 2017-09-26 联合大麻公司 大麻提取物及其制备和使用方法
CN104277917B (zh) * 2014-10-24 2018-02-09 汉康(云南)生物科技有限公司 一种富含大麻二酚的工业大麻精油提取方法及其提取设备
WO2016105514A1 (en) 2014-12-23 2016-06-30 Biotech Institute, Llc A reliable and robust method for the analysis of cannabinoids and terpenes in cannabis
CA2974895A1 (en) 2015-01-25 2016-07-28 India Globalization Capital, Inc. Composition and method for treating seizure disorders
CA3012599A1 (en) 2015-01-26 2016-08-04 Matthew W. Giese Systems, apparatuses, and methods for classification
CA2974292C (en) 2015-01-31 2024-04-16 Constance Therapeutics, Inc. Methods for preparation of cannabis oil extracts and compositions
US10238745B2 (en) 2015-01-31 2019-03-26 Constance Therapeutics, Inc. Cannabinoid composition and products including α-tocopherol
AU2016225026A1 (en) * 2015-02-27 2017-09-07 Canopy Growth Corporation Compositions comprising combinations of purified cannabinoids, with at least one flavonoid, terpene, or mineral
CN107405314A (zh) * 2015-02-27 2017-11-28 埃布公司 包含纯化的大麻素与至少一种类黄酮、萜或矿物质的组合的组合物
US12303541B2 (en) 2015-04-01 2025-05-20 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Erodium crassifolium L'Her plant extracts and uses thereof
EP3277260B1 (en) 2015-04-01 2021-05-12 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) Erodium crassifolium l'her plant extracts and uses thereof
CA2985065A1 (en) * 2015-05-07 2016-11-10 Mark Andrew Scialdone Hydrogenation of cannabis oil
GB2539472A (en) 2015-06-17 2016-12-21 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
EP3319446A4 (en) * 2015-07-06 2019-07-03 Cg- Bio Genomics, Inc. Healthful supplements
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
GB2541191A (en) 2015-08-10 2017-02-15 Gw Pharma Ltd Use of cannabinoids in the treatment of epilepsy
US10596159B2 (en) 2015-08-12 2020-03-24 India Globalization Capital, Inc. Method and composition for treating cachexia and eating disorders
WO2017091764A1 (en) * 2015-11-24 2017-06-01 Constance Therapeutics, Inc. Cannabis oil compositions and methods for preparation thereof
MX421795B (es) * 2016-03-18 2025-03-14 Christopher Brian Reid Composiciones de extractos naturales y uso de los mismos para prevenir o tratar enfermedades
GB2548873B (en) 2016-03-31 2020-12-02 Gw Res Ltd Use of Cannabidiol in the Treatment of SturgeWeber Syndrome
US10499584B2 (en) 2016-05-27 2019-12-10 New West Genetics Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles
CA3027862A1 (en) 2016-06-15 2017-12-21 India Globalization Capital, Inc. Method and composition for treating seizure disorders
GB2551986A (en) 2016-07-01 2018-01-10 Gw Res Ltd Parenteral formulations
GB2551987A (en) 2016-07-01 2018-01-10 Gw Res Ltd Oral cannabinoid formulations
KR20190034576A (ko) * 2016-08-03 2019-04-02 젤다 테라퓨틱스 오퍼레이션즈 피티와이 엘티디 카나비스 조성물
BR112019001852A2 (pt) * 2016-08-03 2019-05-07 Zelda Therapeutics Operations Pty Ltd composição de cannabis
SG11201900596XA (en) * 2016-08-03 2019-02-27 Zelda Therapeutics Operations Pty Ltd Cannabis composition
GB2553139A (en) 2016-08-25 2018-02-28 Gw Res Ltd Use of cannabinoids in the treatment of multiple myeloma
US10568865B2 (en) 2016-08-29 2020-02-25 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
US12485129B2 (en) 2016-08-29 2025-12-02 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
GB2557921A (en) 2016-12-16 2018-07-04 Gw Res Ltd Use of cannabinoids in the treatment of angelman syndrome
GB2559774B (en) 2017-02-17 2021-09-29 Gw Res Ltd Oral cannabinoid formulations
GB2560019A (en) 2017-02-27 2018-08-29 Gw Res Ltd Use of cannabinoids in the treatment of leukaemia
WO2018160827A1 (en) * 2017-03-01 2018-09-07 Ebbu, LLC Compositions purposefully selected comprising purified cannabinoids and/or purified terpenes
EP3592346A4 (en) * 2017-03-05 2020-12-30 The State of Isreal, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER
WO2018205038A1 (en) * 2017-05-12 2018-11-15 Tetra Bio-Pharma Inc. Compositions comprising cannabinoids and terpenes useful in the treatment of cancer and vascular ocular disorders via inhibition of hedgehog signalling
WO2018217803A2 (en) * 2017-05-22 2018-11-29 Growblox Life Sciences L.L.C. Myrcene-containing complex mixtures targeting trpv1
KR20200104278A (ko) 2017-06-19 2020-09-03 젤다 테라퓨틱스 오퍼레이션즈 피티와이 엘티디 수면 장애 조성물 및 그의 치료
JP2020524679A (ja) 2017-06-20 2020-08-20 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム エルティーディー. カンナビジオール酸エステル組成物およびその使用
GB2564383B (en) 2017-06-23 2021-04-21 Gw Res Ltd Use of cannabidiol in the treatment of tumours assoicated with Tuberous Sclerosis Complex
EP3644976A4 (en) * 2017-06-28 2021-03-24 Buzzelet Development And Technologies Ltd TERPEN-ENRICHED CANNABINOID PRODUCT FOR WOMEN'S HEALTH
CA3079537A1 (en) * 2017-09-02 2019-03-07 Scientific Holdings, Llc Tetrahydrocannabinol modulators
GB2568929A (en) 2017-12-01 2019-06-05 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
GB2569961B (en) 2018-01-03 2021-12-22 Gw Res Ltd Pharmaceutical
CN108204786A (zh) * 2018-01-15 2018-06-26 武汉盛硕电子有限公司 一种基于手机模块的北斗测量系统
US10688191B2 (en) 2018-01-19 2020-06-23 Hr Biomed, Llc Delivery of a chemotherapy agent across the blood-brain barrier
AU2019210332A1 (en) * 2018-01-22 2020-09-10 Pascal Biosciences Inc. Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
WO2019157195A1 (en) 2018-02-08 2019-08-15 Neonc Technologies, Inc Methods of permeabilizing the blood brain barrier
KR102041875B1 (ko) 2018-02-14 2019-11-08 (주)카이언바이오텍 대마로부터 추출된 칸나비디올 추출물 및 트레일을 함유하는 대장암 예방 또는 치료용 약학 조성물
KR20190098649A (ko) 2018-02-14 2019-08-22 (주)카이언바이오텍 칸나비디올 추출물을 함유하는 대장암 예방 또는 치료용 약학 조성물
EP3755318B1 (en) * 2018-02-20 2022-08-24 MyMD Pharmaceuticals, Inc. Genetically modified cannabis sativa plants and modified cannabinoid compounds for treatment of substance addiction and other disorders
CA3095729A1 (en) 2018-03-30 2019-10-03 India Globalization Capital, Inc. Method and composition for treating cns disorders
EP3773722A1 (en) 2018-04-04 2021-02-17 Jay Pharma Inc. Combination of a cannabinoid and a chemotheraopeutic agent for the treatment of breast cancer
MX2020010603A (es) 2018-04-09 2021-02-02 Ellevet Sciences Extracto de cáñamo para tratamiento de dolor en animales.
WO2019227167A1 (en) * 2018-06-01 2019-12-05 The University Of Sydney Compositions and treatments
WO2020012315A1 (en) 2018-07-08 2020-01-16 Buzzelet Development And Technologies Ltd. Terpene-enriched cannabinoid composition for treatment of male subjects
EP3666765A1 (en) * 2018-12-11 2020-06-17 Emerald Health Biotechnology España,S.L.U. Chromenic phytocannabinoids, their synthesis and use in treatment or prevention of disease
CA3123773A1 (en) * 2018-12-12 2020-06-18 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Compositions and methods for the treatment of cutaneous t cell lymphoma (ctcl)
CA3128054A1 (en) * 2019-01-31 2020-08-06 Cava Healthcare Inc. Compounds for increasing mhc-i expression and modulating histone deacetylase activity
NL2022614B1 (en) * 2019-02-21 2020-08-31 Patrick Alexander Unger Pharmaceutical, phyto-cannabinoid based compositions
MX2021010875A (es) 2019-03-12 2021-12-10 Epm Ip Inc Composiciones de éster de ácido cannabinoide y sus usos.
EP3946307A4 (en) * 2019-04-02 2022-12-14 Ulagaraj Selvaraj SOLID NANOPARTICLE FORMULATION OF WATER-INSOLUBLE PHARMACEUTICAL SUBSTANCES WITH REDUCED OSTWALD RIPENING AND IMMEDIATE DRUG RELEASE AFTER INTRAVENOUS ADMINISTRATION
ES2986503T3 (es) 2019-05-03 2024-11-11 Zyus Life Sciences Inc Formulación para el manejo del dolor que comprende tetrahidrocannabinol (THC), cannabicromeno (CBC) y cannabidiol (CBD) en una proporción determinada
US12178797B2 (en) 2019-05-03 2024-12-31 Zyus Life Sciences Inc. Formulation for pain management
US12220396B2 (en) 2019-05-03 2025-02-11 Zyus Life Sciences Inc. Formulation for pain management
CA3140290A1 (en) * 2019-05-16 2020-11-19 Technion Research & Development Foundation Limited Cannabinoids and uses thereof
GB201910389D0 (en) 2019-07-19 2019-09-04 Gw Pharma Ltd Novel compounds, methods for their manufacture, and uses thereof
GB2588576A (en) 2019-08-27 2021-05-05 Gw Res Ltd Use of cannabinoids in the treatment of dyskinesia associated with Parkinson's disease
GB201916849D0 (en) 2019-11-19 2020-01-01 Gw Res Ltd Cannabidiol-type cannabinoid compound
GB201916846D0 (en) 2019-11-19 2020-01-01 Gw Res Ltd Cannabidiol-type cannabinoid compound
GB201916974D0 (en) 2019-11-21 2020-01-08 Gw Res Ltd Cannabidol-type cannabinoid compound
GB202002754D0 (en) 2020-02-27 2020-04-15 Gw Res Ltd Methods of treating tuberous sclerosis complex with cannabidiol and everolimus
CN111184710A (zh) * 2020-03-02 2020-05-22 福建省中科生物股份有限公司 一种环酚的应用和制备方法
CA3175684A1 (en) 2020-04-29 2021-11-04 Jon Penarando Saez Cannabinoids for use in supressing cancer stem cells
EP3912485A1 (en) 2020-05-18 2021-11-24 Del-Vis Sp. z o.o. Cigarette product and a method for manufacturing the product
CN111773390B (zh) * 2020-07-01 2021-08-20 南京大学 一种药物在制备治疗脑转移瘤及其相关疾病的药品中的应用
JP2023534073A (ja) * 2020-07-22 2023-08-07 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 銀強化カンナビノイド抗生物質
EP4203925A1 (en) * 2020-08-31 2023-07-05 Nelson Mandela University Cannabinoid combinations and their use in the treatment of cancer
US11160757B1 (en) 2020-10-12 2021-11-02 GW Research Limited pH dependent release coated microparticle cannabinoid formulations
US20240041902A1 (en) * 2020-12-08 2024-02-08 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization Compositions and methods for the treatment of urothelial cancer
WO2022215071A1 (en) * 2021-04-05 2022-10-13 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Institute) Compositions and methods for the treatment of cancer
WO2022232574A1 (en) 2021-04-29 2022-11-03 Tilray, Inc. Cannabidiol-dominant formulations, methods of manufacturing, and uses thereof
EP4422769A2 (en) 2021-10-26 2024-09-04 Ecofibre USA Inc. Systems and methods for producing hemp extracts and compositions
WO2023076937A1 (en) 2021-10-26 2023-05-04 Ecofibre Limited Methods of treating endometriosis and other non-cancer gynecological disorders with hemp extract
JP2024540177A (ja) 2021-10-26 2024-10-31 エコファイバー ユーエスエイ インコーポレイテッド ヘンプ抽出物を使用する子宮内膜がんを処置する方法
WO2023130161A1 (en) * 2022-01-10 2023-07-13 Dolce Cann Global Pty Ltd Compositions and methods for treating non-neurological disorders with combination products comprising a cannabinoid mixture rich in cannabidiolic acid (cbda) along with an additional active agent
WO2023130160A1 (en) * 2022-01-10 2023-07-13 Dolce Cann Global Pty Ltd Compositions and methods for treating non-neurological disorders with combination products comprising a cannabinoid mixture rich in cannabidiolic acid (cbda).
US12440454B2 (en) 2022-02-01 2025-10-14 Portland Technology Holdings Llc Pharmaceutical compositions containing hemp extract for administration to felines and related methods
WO2023161921A2 (en) * 2022-02-23 2023-08-31 Cannabotech Ltd. Compositions for use as an adjunctive therapy in the treatment of breast cancer
WO2023239415A1 (en) * 2022-06-08 2023-12-14 Angrow Company Limited Compositions including cannabinoid and use thereof in the manufacture of a medicament for the treatment of inflammation in a subject
WO2023238114A1 (en) * 2022-06-08 2023-12-14 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Institute) Combinations and methods for the treatment of cancer
WO2024082014A1 (en) * 2022-10-21 2024-04-25 Dolce Cann Global Pty Ltd Compositions comprising cannabidiolic acid and fatty acids
EP4608426A1 (en) 2022-10-26 2025-09-03 Ecofibre USA Inc. Stabilized compositions comprising cannabidiol
US12097211B2 (en) 2022-10-26 2024-09-24 Ecofibre USA Inc. Methods of treating estrogen sensitive diseases with cannabis extract
CN115583933B (zh) * 2022-10-31 2024-02-06 暨明医药科技(苏州)有限公司 一种高纯度四氢大麻素同系物的制备方法

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2238707A (en) 1989-12-08 1991-06-12 Peter Bullock Repairing footwear
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US20040039048A1 (en) 2000-02-11 2004-02-26 Manuel Guzman Pastor Therapy with cannabinoid compounds for the treatment of brain tumors
ES1045342Y (es) 2000-02-11 2001-02-16 Alvarez Manuel Couto Expositor giratorio para postales, fotos y similares.
ES2164584A1 (es) 2000-02-11 2002-02-16 Univ Madrid Complutense Terapia con cannabinoides para el tratamiento de tumores cerebrales.
US6448288B1 (en) 2000-05-17 2002-09-10 University Of Massachusetts Cannabinoid drugs
EP1326996A4 (en) 2000-09-14 2005-08-24 Univ California ID-1 AND ID-2 GENES AND PRODUCTS AS DIAGNOSTIC OR PROGNOSTIC MARKERS AND THERAPEUTIC TARGETS FOR THE TREATMENT OF BREAST CANCER AND OTHER TYPES OF CARCINOMA
DE10051427C1 (de) * 2000-10-17 2002-06-13 Adam Mueller Verfahren zur Herstellung eines Tetrahydrocannabinol- und Cannabidiol-haltigen Extraktes aus Cannabis-Pflanzenmaterial sowie Cannabis-Extrakte
US7025992B2 (en) 2001-02-14 2006-04-11 Gw Pharma Limited Pharmaceutical formulations
GB2380129B (en) 2001-02-14 2004-08-11 Gw Pharma Ltd Pharmaceutical formulations
CH695661A5 (de) 2001-03-06 2006-07-31 Forsch Hiscia Ver Fuer Krebsfo Pharmazeutische Zusammensetzung.
GB0202385D0 (en) * 2002-02-01 2002-03-20 Gw Pharma Ltd Compositions for the treatment of nausea,vomiting,emesis,motion sicknes or like conditions
WO2003063847A1 (en) 2002-02-01 2003-08-07 Gw Pharma Limited Compositions comprising cannabinoids for treatment of nausea, vomiting, emesis, motion sickness or like conditions
US20080057117A1 (en) 2002-02-15 2008-03-06 Forschungs Institut Miscia Verenfur Krebsforschung Pharmaceutical composition made up of cannibus extracts
IL148244A0 (en) 2002-02-19 2002-09-12 Yissum Res Dev Co Anti-nausea and anti-vomiting activity of cannabidiol compounds
US7285687B2 (en) 2002-04-25 2007-10-23 Virginia Commonwealth University Cannabinoids
GB2391865B (en) 2002-08-14 2005-06-01 Gw Pharma Ltd Improvements in the extraction of pharmaceutically active components from plant materials
US6946150B2 (en) 2002-08-14 2005-09-20 Gw Pharma Limited Pharmaceutical formulation
GB2394894B (en) 2002-11-04 2005-08-31 G W Pharma Ltd New use for pharmaceutical composition
GB2414933B (en) 2004-06-08 2009-07-15 Gw Pharma Ltd Cannabinoid compositions for the treatment of disease and/or symptoms in arthritis
GB2418612A (en) * 2004-10-01 2006-04-05 Gw Pharma Ltd Inhibition of tumour cell migration with cannabinoids
KR101288729B1 (ko) 2005-04-01 2013-07-23 인터자인 테크놀로지스, 인코포레이티드 약물 전달용 중합체성 마이셀
US7968594B2 (en) 2005-04-27 2011-06-28 Gw Pharma Limited Pharmaceutical compositions for the treatment of pain
EP1881757A4 (en) 2005-05-13 2008-09-10 Unimed Pharmaceuticals Inc DRONABINOL TREATMENT OF CHEMOTHERAPY-INDUCED POSSIBLE INCOMPATIBILITY AND ILLUSTRATION
GB2434312B (en) * 2006-01-18 2011-06-29 Gw Pharma Ltd Cannabinoid-containing plant extracts as neuroprotective agents
GB2438682A (en) 2006-06-01 2007-12-05 Gw Pharma Ltd New use for cannabinoids
GB2439393B (en) * 2006-06-23 2011-05-11 Gw Pharma Ltd Cannabinoids for use in the treatment of neuropathic pain
US20080103193A1 (en) * 2006-10-26 2008-05-01 Trevor Percival Castor Methods for making compositions and compositions for treating pain and cachexia
US20100152238A1 (en) * 2007-03-05 2010-06-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Novel quinonoid derivatives of cannabinoids and their use in the treatment of malignancies
GB2448535A (en) * 2007-04-19 2008-10-22 Gw Pharma Ltd New use for cannabinoid-containing plant extracts
WO2008144475A1 (en) 2007-05-17 2008-11-27 California Pacific Medical Center Methods and compositions for treating cancer
GB2449691A (en) * 2007-05-31 2008-12-03 Gw Pharma Ltd A reference plant lacking medicinal active compound expression
GB2450741A (en) * 2007-07-05 2009-01-07 Gw Pharma Ltd Cannabinoid containing plant extracts in the treatment of inflammatory bowel disease
ES2359168T3 (es) * 2007-10-02 2011-05-19 Vivacell Biotechnology España S.L. Composición que comprende cannabinoides no psicotrópicos para el tratamiento de enfermedades antiinflamatorias.
GB2456183A (en) * 2008-01-04 2009-07-08 Gw Pharma Ltd Anti-psychotic composition comprising cannabinoids and anti-psychotic medicament
GB2471987B (en) 2008-06-04 2012-02-22 Gw Pharma Ltd Anti-tumoural effects of cannabinoid combinations
GB2460672B (en) * 2008-06-04 2012-01-04 Gw Pharma Ltd Cannabinoids in combination with non-cannabinoid chemotherapeutic agents that are alkylating agents
GB2478595B (en) 2010-03-12 2018-04-04 Gw Pharma Ltd Phytocannabinoids in the treatment of glioma

Also Published As

Publication number Publication date
AU2011225837A1 (en) 2012-11-01
PH12012501782A1 (en) 2012-11-12
BR112012023017A8 (pt) 2018-04-03
JP5785569B2 (ja) 2015-09-30
GB2478595B (en) 2018-04-04
HUE029817T2 (en) 2017-04-28
WO2011110866A1 (en) 2011-09-15
KR20130067248A (ko) 2013-06-21
US20150086653A1 (en) 2015-03-26
JP2013522184A (ja) 2013-06-13
DK2544682T3 (en) 2016-05-09
IL221871A (en) 2017-03-30
GB201004137D0 (en) 2010-04-28
AU2016266059A1 (en) 2016-12-22
TW201201828A (en) 2012-01-16
UA109271C2 (uk) 2015-08-10
US9675654B2 (en) 2017-06-13
AU2018217273B2 (en) 2020-03-12
CY1117451T1 (el) 2017-04-26
NZ602953A (en) 2014-09-26
US8790719B2 (en) 2014-07-29
US20130059018A1 (en) 2013-03-07
CN102869356A (zh) 2013-01-09
CO6630103A2 (es) 2013-03-01
GB2478595A (en) 2011-09-14
NZ629136A (en) 2016-03-31
HRP20160427T1 (hr) 2016-07-01
BR112012023017A2 (pt) 2016-05-31
TWI461205B (zh) 2014-11-21
MX2012010512A (es) 2012-10-15
SG184016A1 (en) 2012-10-30
CA2792722A1 (en) 2011-09-15
SI2544682T1 (sl) 2016-06-30
EP2544682A1 (en) 2013-01-16
ZA201207574B (en) 2014-09-25
ES2569669T3 (es) 2016-05-12
EP2544682B1 (en) 2016-02-10
US20180042975A1 (en) 2018-02-15
AR080454A1 (es) 2012-04-11
EA201290901A1 (ru) 2013-04-30
AU2018217273A1 (en) 2018-08-30

Similar Documents

Publication Publication Date Title
NL301340I2 (nl) tisotumab vedotin
NO2022039I1 (no) Enfortumab vedotin
PL2544682T3 (pl) Fitokannabinoidy w leczeniu glejaka
BR112012017441A2 (pt) compostos e métodos
PL2523678T3 (pl) Antagoniści Wnt i sposoby leczenia
IT1400425B1 (it) Modified snrnas for use in therapy.
SMT201600050B (it) Mezzi e metodi per trattare il dlbcl
DK2552261T3 (da) Propfilter med proprum med aromakugle
HRP20160737T1 (hr) Anti-her3-protutijela i njihove uporabe
DK2538984T3 (da) Kompressionsforbinding
LT2605789T (lt) Modifikuoti relaksino polipeptidai ir jų panaudojimas
DK3124610T3 (da) Hbv-behandling
DK2613884T3 (da) Findelingsindretning
IL232262A (en) Therapeutic agents and uses thereof
HRP20171579T8 (hr) Antigljivična sredstva i njihova upotreba
HRP20160922T1 (hr) Oligopeptidni spojevi i njihove uporabe
HRP20170936T1 (hr) Alkilamido spojevi i njihova uporaba
EP2872036A4 (en) IN VIVO BIOSENSOR
FR2963612B1 (fr) Element en treillis et grue
EP2613409A4 (en) Connector
EP2543712A4 (en) IN COOLING MEDIUM
IL229767A0 (en) Glioblastoma inhibiting compounds and their use
HRP20170225T1 (hr) Fosfoplatini i njihova uporaba za liječenje karcinoma
HRP20160929T1 (hr) Terapijski režimi
EP2415408A4 (en) Treatment device