DK3190128T3 - Sammensætninger og fremgangsmåder til behandling af ige-medierede forstyrrelser - Google Patents

Sammensætninger og fremgangsmåder til behandling af ige-medierede forstyrrelser Download PDF

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Publication number
DK3190128T3
DK3190128T3 DK16170993.6T DK16170993T DK3190128T3 DK 3190128 T3 DK3190128 T3 DK 3190128T3 DK 16170993 T DK16170993 T DK 16170993T DK 3190128 T3 DK3190128 T3 DK 3190128T3
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gly
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DK16170993.6T
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English (en)
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John R Desjarlais
Seung Y Chu
Holly M Horton
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Xencor Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Claims (1)

1. Antistof til anvendelse i behandlingen af allergisk astma hos et individ med behov derfor, hvilket antistof omfatter: a. en tungkæde med SEQ ID NO: 42 og b. en letkæde med SEQ ID NO: 40.
DK16170993.6T 2008-09-17 2009-09-17 Sammensætninger og fremgangsmåder til behandling af ige-medierede forstyrrelser DK3190128T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9781908P 2008-09-17 2008-09-17
EP14188102.9A EP2853545B8 (en) 2008-09-17 2009-09-17 Antibody specific for IgE

Publications (1)

Publication Number Publication Date
DK3190128T3 true DK3190128T3 (da) 2019-01-28

Family

ID=41510648

Family Applications (3)

Application Number Title Priority Date Filing Date
DK14188102.9T DK2853545T3 (da) 2008-09-17 2009-09-17 Antistof specifikt for IgE
DK14167234.5T DK2796469T3 (da) 2008-09-17 2009-09-17 Hidtil ukendte sammensætninger og fremgangsmåder til behandling af IgE-medierede forstyrrelser
DK16170993.6T DK3190128T3 (da) 2008-09-17 2009-09-17 Sammensætninger og fremgangsmåder til behandling af ige-medierede forstyrrelser

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK14188102.9T DK2853545T3 (da) 2008-09-17 2009-09-17 Antistof specifikt for IgE
DK14167234.5T DK2796469T3 (da) 2008-09-17 2009-09-17 Hidtil ukendte sammensætninger og fremgangsmåder til behandling af IgE-medierede forstyrrelser

Country Status (20)

Country Link
US (9) US8435517B2 (da)
EP (7) EP2331578B1 (da)
JP (2) JP5785493B2 (da)
KR (1) KR101783272B1 (da)
CN (2) CN104961830B (da)
AU (1) AU2009293143C1 (da)
BR (1) BRPI0918670B8 (da)
CA (1) CA2736511C (da)
CY (2) CY1118002T1 (da)
DK (3) DK2853545T3 (da)
ES (6) ES2927192T3 (da)
HR (1) HRP20182135T1 (da)
HU (2) HUE042901T2 (da)
LT (2) LT3190128T (da)
PL (2) PL2853545T3 (da)
PT (2) PT2853545T (da)
SI (2) SI2853545T1 (da)
SM (1) SMT201600288B (da)
TR (1) TR201821216T4 (da)
WO (1) WO2010033736A1 (da)

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