PL2853545T3 - Przeciwciało swoiste wobec IgE - Google Patents
Przeciwciało swoiste wobec IgEInfo
- Publication number
- PL2853545T3 PL2853545T3 PL14188102.9T PL14188102T PL2853545T3 PL 2853545 T3 PL2853545 T3 PL 2853545T3 PL 14188102 T PL14188102 T PL 14188102T PL 2853545 T3 PL2853545 T3 PL 2853545T3
- Authority
- PL
- Poland
- Prior art keywords
- ige
- antibody specific
- antibody
- specific
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
- C07K16/4291—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
- C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9781908P | 2008-09-17 | 2008-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2853545T3 true PL2853545T3 (pl) | 2016-12-30 |
Family
ID=41510648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14188102.9T PL2853545T3 (pl) | 2008-09-17 | 2009-09-17 | Przeciwciało swoiste wobec IgE |
| PL16170993T PL3190128T3 (pl) | 2008-09-17 | 2009-09-17 | Kompozycje i sposoby leczenia zaburzeń, w których pośredniczy IgE |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16170993T PL3190128T3 (pl) | 2008-09-17 | 2009-09-17 | Kompozycje i sposoby leczenia zaburzeń, w których pośredniczy IgE |
Country Status (20)
| Country | Link |
|---|---|
| US (9) | US8435517B2 (pl) |
| EP (7) | EP2796469B1 (pl) |
| JP (2) | JP5785493B2 (pl) |
| KR (1) | KR101783272B1 (pl) |
| CN (2) | CN104961830B (pl) |
| AU (1) | AU2009293143C1 (pl) |
| BR (1) | BRPI0918670B8 (pl) |
| CA (1) | CA2736511C (pl) |
| CY (2) | CY1118002T1 (pl) |
| DK (3) | DK2796469T3 (pl) |
| ES (6) | ES2499031T3 (pl) |
| HR (1) | HRP20182135T1 (pl) |
| HU (2) | HUE029341T2 (pl) |
| LT (2) | LT3190128T (pl) |
| PL (2) | PL2853545T3 (pl) |
| PT (2) | PT2853545T (pl) |
| SI (2) | SI2853545T1 (pl) |
| SM (1) | SMT201600288B (pl) |
| TR (1) | TR201821216T4 (pl) |
| WO (1) | WO2010033736A1 (pl) |
Families Citing this family (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090010920A1 (en) | 2003-03-03 | 2009-01-08 | Xencor, Inc. | Fc Variants Having Decreased Affinity for FcyRIIb |
| US9051373B2 (en) * | 2003-05-02 | 2015-06-09 | Xencor, Inc. | Optimized Fc variants |
| US8168181B2 (en) | 2006-02-13 | 2012-05-01 | Alethia Biotherapeutics, Inc. | Methods of impairing osteoclast differentiation using antibodies that bind siglec-15 |
| CA2638823A1 (en) | 2006-02-13 | 2007-08-23 | Alethia Biotherapeutics Inc. | Polynucleotides and polypeptide sequences involved in the process of bone remodeling |
| IN2014DN10515A (pl) | 2006-03-31 | 2015-08-21 | Chugai Pharmaceutical Co Ltd | |
| DK2176298T3 (en) * | 2007-05-30 | 2018-02-12 | Xencor Inc | Methods and compositions for inhibiting CD32B-expressing cells |
| MX336725B (es) | 2007-09-26 | 2016-01-28 | Chugai Pharmaceutical Co Ltd | Metodo de modificacion del punto isoelectrico de anticuerpos medinate la sustitucion de aminoacidos en region de determinacion de complementariedad (cdr). |
| TWI700293B (zh) | 2008-04-11 | 2020-08-01 | 日商中外製藥股份有限公司 | 重複結合複數個抗原的抗體 |
| WO2010033736A1 (en) * | 2008-09-17 | 2010-03-25 | Xencor, Inc. | Novel compositons and methods for treating ige-mediated disorders |
| US20170247470A9 (en) * | 2008-09-17 | 2017-08-31 | Xencor, Inc. | Rapid clearance of antigen complexes using novel antibodies |
| ES2615881T3 (es) * | 2009-05-07 | 2017-06-08 | Stallergenes | Uso de inmunoglobulinas igg1 y/o de ligandos del receptor cd32 para el tratamiento de enfermedades y manifestaciones inflamatorias por vía mucosa. |
| US9493578B2 (en) | 2009-09-02 | 2016-11-15 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
| WO2011097527A2 (en) * | 2010-02-04 | 2011-08-11 | Xencor, Inc. | Immunoprotection of therapeutic moieties using enhanced fc regions |
| US20110189178A1 (en) * | 2010-02-04 | 2011-08-04 | Xencor, Inc. | Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions |
| KR101818274B1 (ko) | 2010-05-27 | 2018-01-12 | 머크 샤프 앤드 돔 코포레이션 | 개선된 특성을 갖는 항체의 제조 방법 |
| CN103154242B (zh) * | 2010-07-06 | 2015-09-30 | 诺华股份有限公司 | 诺如病毒衍生的免疫原性组合物和方法 |
| EP3029066B1 (en) | 2010-07-29 | 2019-02-20 | Xencor, Inc. | Antibodies with modified isoelectric points |
| US10017762B2 (en) * | 2010-11-24 | 2018-07-10 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Compositions and methods for treating or preventing lupus |
| KR102568454B1 (ko) | 2010-11-30 | 2023-08-18 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복해서 결합하는 항원 결합 분자 |
| EP2656073A4 (en) * | 2010-12-20 | 2014-12-17 | Univ Rockefeller | Modulating agonistic tnfr antibodies |
| WO2012109280A2 (en) * | 2011-02-07 | 2012-08-16 | Neotope Biosciences Limited | Apoe immunotherapy |
| WO2012162277A1 (en) * | 2011-05-25 | 2012-11-29 | Merck Sharp & Dohme Corp. | METHOD FOR PREPARING Fc-CONTAINING POLYPEPTIDES HAVING IMPROVED PROPERTIES |
| US10851178B2 (en) | 2011-10-10 | 2020-12-01 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| US12466897B2 (en) | 2011-10-10 | 2025-11-11 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| JP2015502397A (ja) | 2011-12-23 | 2015-01-22 | ファイザー・インク | 部位特異的コンジュゲーションのための操作された抗体定常領域、ならびにそのための方法および使用 |
| ES2723885T3 (es) | 2012-07-19 | 2019-09-03 | Daiichi Sankyo Co Ltd | Anticuerpos anti-Siglec-15 |
| EP3597747B1 (en) | 2012-08-24 | 2023-03-15 | Chugai Seiyaku Kabushiki Kaisha | Mouse fcgammarii-specific fc antibody |
| TWI855488B (zh) | 2012-08-24 | 2024-09-11 | 日商中外製藥股份有限公司 | FcγRIIb特異性Fc區域變異體 |
| WO2014072876A1 (en) | 2012-11-09 | 2014-05-15 | Pfizer Inc. | Platelet-derived growth factor b specific antibodies and compositions and uses thereof |
| US9605084B2 (en) | 2013-03-15 | 2017-03-28 | Xencor, Inc. | Heterodimeric proteins |
| US11053316B2 (en) | 2013-01-14 | 2021-07-06 | Xencor, Inc. | Optimized antibody variable regions |
| US10131710B2 (en) | 2013-01-14 | 2018-11-20 | Xencor, Inc. | Optimized antibody variable regions |
| US10487155B2 (en) | 2013-01-14 | 2019-11-26 | Xencor, Inc. | Heterodimeric proteins |
| CN105051069B (zh) | 2013-01-14 | 2019-12-10 | Xencor股份有限公司 | 新型异二聚体蛋白 |
| US9701759B2 (en) | 2013-01-14 | 2017-07-11 | Xencor, Inc. | Heterodimeric proteins |
| US10968276B2 (en) | 2013-03-12 | 2021-04-06 | Xencor, Inc. | Optimized anti-CD3 variable regions |
| US9738722B2 (en) | 2013-01-15 | 2017-08-22 | Xencor, Inc. | Rapid clearance of antigen complexes using novel antibodies |
| US10858417B2 (en) | 2013-03-15 | 2020-12-08 | Xencor, Inc. | Heterodimeric proteins |
| EP3421495A3 (en) | 2013-03-15 | 2019-05-15 | Xencor, Inc. | Modulation of t cells with bispecific antibodies and fc fusions |
| US10519242B2 (en) | 2013-03-15 | 2019-12-31 | Xencor, Inc. | Targeting regulatory T cells with heterodimeric proteins |
| US10106624B2 (en) | 2013-03-15 | 2018-10-23 | Xencor, Inc. | Heterodimeric proteins |
| AU2014250434B2 (en) | 2013-04-02 | 2019-08-08 | Chugai Seiyaku Kabushiki Kaisha | Fc region variant |
| GB201308658D0 (en) * | 2013-05-14 | 2013-06-26 | Isis Innovation | Antibodies |
| EP3066133A1 (en) | 2013-11-04 | 2016-09-14 | Glenmark Pharmaceuticals S.A. | Production of t cell retargeting hetero-dimeric immunoglobulins |
| AU2014348676B2 (en) | 2013-11-13 | 2020-06-18 | Bristol-Myers Squibb Company | Tumor necrosis factor-like ligand 1A specific antibodies and compositions and uses thereof |
| WO2015109212A1 (en) | 2014-01-17 | 2015-07-23 | Pfizer Inc. | Anti-il-2 antibodies and compositions and uses thereof |
| KR102497443B1 (ko) | 2014-03-28 | 2023-02-08 | 젠코어 인코포레이티드 | Cd38 및 cd3에 결합하는 이중특이적 항체 |
| WO2015153678A2 (en) * | 2014-04-02 | 2015-10-08 | Tunitas Therapeutics, Inc. | Epsigam fusion protein |
| CA2956178A1 (en) | 2014-07-24 | 2016-01-28 | Xencor, Inc. | Rapid clearance of antigen complexes using novel antibodies |
| US11773166B2 (en) | 2014-11-04 | 2023-10-03 | Ichnos Sciences SA | CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production |
| CA2967426A1 (en) | 2014-11-26 | 2016-06-02 | Xencor, Inc. | Heterodimeric antibodies that bind cd3 and tumor antigens |
| BR112017011166A2 (pt) | 2014-11-26 | 2018-02-27 | Xencor, Inc. | anticorpos heterodiméricos que se ligam a cd3 e cd38 |
| US10259887B2 (en) | 2014-11-26 | 2019-04-16 | Xencor, Inc. | Heterodimeric antibodies that bind CD3 and tumor antigens |
| TWI656133B (zh) | 2014-12-19 | 2019-04-11 | 日商中外製藥股份有限公司 | 抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法 |
| EP3237449A2 (en) | 2014-12-22 | 2017-11-01 | Xencor, Inc. | Trispecific antibodies |
| WO2016125495A1 (en) | 2015-02-05 | 2016-08-11 | Chugai Seiyaku Kabushiki Kaisha | Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof |
| WO2016141387A1 (en) | 2015-03-05 | 2016-09-09 | Xencor, Inc. | Modulation of t cells with bispecific antibodies and fc fusions |
| AR104368A1 (es) | 2015-04-03 | 2017-07-19 | Lilly Co Eli | Anticuerpos biespecíficos anti-cd20- / anti-baff |
| US11066481B2 (en) | 2015-07-23 | 2021-07-20 | The Regents Of The University Of California | Antibodies to coagulation factor XIa and uses thereof |
| KR102876923B1 (ko) | 2015-10-23 | 2025-10-28 | 화이자 인코포레이티드 | 항-il-2 항체 및 조성물 및 이의 용도 |
| CN108699136B (zh) | 2015-12-07 | 2022-03-18 | Xencor股份有限公司 | 结合cd3和psma的异二聚抗体 |
| WO2017110981A1 (en) | 2015-12-25 | 2017-06-29 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| CA3026151A1 (en) | 2016-06-14 | 2017-12-21 | Xencor, Inc. | Bispecific checkpoint inhibitor antibodies |
| MX2018016265A (es) | 2016-06-28 | 2019-07-04 | Xencor Inc | Anticuerpos heterodimericos que se unen al receptor 2 de somatostatina. |
| CN109689099B (zh) | 2016-08-05 | 2023-02-28 | 中外制药株式会社 | 用于预防或治疗il-8相关疾病的组合物 |
| US10793632B2 (en) | 2016-08-30 | 2020-10-06 | Xencor, Inc. | Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors |
| SG10201607778XA (en) | 2016-09-16 | 2018-04-27 | Chugai Pharmaceutical Co Ltd | Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use |
| PE20240950A1 (es) | 2016-10-14 | 2024-05-06 | Xencor Inc | PROTEINAS DE FUSION FC HETERODIMERICAS IL 15/IL 15R(alfa) |
| CA3045797A1 (en) * | 2016-12-02 | 2018-06-07 | The Texas A&M University System | Fusion proteins for selectively depleting antigen-specific antibodies |
| AU2018291497A1 (en) | 2017-06-30 | 2020-01-16 | Xencor, Inc. | Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15Ra and antigen binding domains |
| JP7279011B2 (ja) | 2017-07-10 | 2023-05-22 | インターナショナル-ドラッグ-ディベロップメント-バイオテック | 抗cd20抗体または化学療法薬と併用して非フコシル化アポトーシス促進性抗cd19抗体を用いるb細胞悪性の治療 |
| KR20200085828A (ko) | 2017-11-08 | 2020-07-15 | 젠코어 인코포레이티드 | 신규의 항-pd-1 서열을 사용한 이중특이적 및 단일특이적 항체 |
| US10981992B2 (en) | 2017-11-08 | 2021-04-20 | Xencor, Inc. | Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors |
| EP3728302A1 (en) | 2017-12-19 | 2020-10-28 | Xencor, Inc. | Engineered il-2 fc fusion proteins |
| WO2019135666A1 (ko) | 2018-01-08 | 2019-07-11 | 주식회사 프로젠 | Ige fc 수용체의 알파 서브유닛의 세포외 도메인을 포함하는 약학적 조성물 |
| US12410233B2 (en) | 2018-01-08 | 2025-09-09 | Gi Innovation, Inc. | Extracellular domain of alpha subunit of IgE Fc receptor, pharmaceutical composition comprising same and method for producing same |
| SG11202005863TA (en) | 2018-01-12 | 2020-07-29 | Gi Innovation Inc | Composition comprising probiotics and polypeptide having binding affinity for ige and use thereof |
| EP3749362A1 (en) * | 2018-02-09 | 2020-12-16 | F. Hoffmann-La Roche AG | Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases |
| US20200040103A1 (en) | 2018-03-14 | 2020-02-06 | Genentech, Inc. | Anti-klk5 antibodies and methods of use |
| IL277375B2 (en) | 2018-03-15 | 2025-08-01 | Chugai Pharmaceutical Co Ltd | Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use |
| EP3773911A2 (en) | 2018-04-04 | 2021-02-17 | Xencor, Inc. | Heterodimeric antibodies that bind fibroblast activation protein |
| KR20210003814A (ko) | 2018-04-18 | 2021-01-12 | 젠코어 인코포레이티드 | IL-15/IL-15Rα Fc-융합 단백질 및 TIM-3 항원 결합 도메인을 함유하는 TIM-3 표적화 이종이량체 융합 단백질 |
| MX2020010910A (es) | 2018-04-18 | 2021-02-09 | Xencor Inc | Proteinas de fusion heterodimericas dirigidas a pd-1 que contienen proteinas de fusion il-15 / il-15ra fc y dominios de union al antigeno pd-1 y usos de los mismos. |
| JP7403479B2 (ja) | 2018-06-03 | 2023-12-22 | ランカプ バイオ ベータ リミテッド | Ceacam5およびcd47に対する二重特異性抗体 |
| MX2021003765A (es) | 2018-10-03 | 2021-07-15 | Xencor Inc | Proteínas il-12 de fusión a fc heterodimérico. |
| US20220105179A1 (en) * | 2019-02-21 | 2022-04-07 | The General Hospital Corporation | Glycoengineering immunoglobulin e |
| AU2020232605A1 (en) | 2019-03-01 | 2021-10-21 | Xencor, Inc. | Heterodimeric antibodies that bind ENPP3 and CD3 |
| BR112022000246A2 (pt) | 2019-07-08 | 2022-02-22 | Gi Innovation Inc | Dímero polipeptídico com elevado teor de ácido siálico, compreendendo o domínio extracelular da subunidade alfa do receptor fc de ige e composição farmacêutica compreendendo o mesmo |
| CN114423791B (zh) | 2019-09-18 | 2026-01-09 | 豪夫迈·罗氏有限公司 | 抗klk7抗体、抗klk5抗体、多特异性抗klk5/klk7抗体及使用方法 |
| CN110836935B (zh) * | 2019-11-25 | 2022-01-28 | 重庆柳江医药科技有限公司 | 测定甲磺司特原料药中3种基因毒性杂质的方法 |
| EP3831849A1 (en) | 2019-12-02 | 2021-06-09 | LamKap Bio beta AG | Bispecific antibodies against ceacam5 and cd47 |
| US11919956B2 (en) | 2020-05-14 | 2024-03-05 | Xencor, Inc. | Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3 |
| JP7756664B2 (ja) | 2020-07-01 | 2025-10-20 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 経口免疫療法のための医療スタッフ配置の決定 |
| JP7773528B2 (ja) | 2020-08-19 | 2025-11-19 | ゼンコア インコーポレイテッド | 抗cd28組成物 |
| RS65211B1 (sr) | 2020-12-18 | 2024-03-29 | Lamkap Bio Beta Ag | Bispecifična antitela protiv ceacam5 i cd47 |
| EP4306103B1 (en) | 2021-03-09 | 2025-12-24 | GI Innovation, Inc. | Formulation of fusion protein including extracellular domain of alpha subunit of ige fc receptor |
| CA3212665A1 (en) | 2021-03-09 | 2022-09-15 | Xencor, Inc. | Heterodimeric antibodies that bind cd3 and cldn6 |
| KR20230154311A (ko) | 2021-03-10 | 2023-11-07 | 젠코어 인코포레이티드 | Cd3 및 gpc3에 결합하는 이종이량체 항체 |
| KR20250025384A (ko) | 2022-06-16 | 2025-02-21 | 람카프 바이오 베타 엘티디. | Ceacam5 및 cd47에 대한 이중특이적 항체 및 ceacam5 및 cd3에 대한 이중특이적 항체의 조합 요법 |
| EP4547710A1 (en) | 2022-07-01 | 2025-05-07 | ALK-Abelló A/S | Displacers of ige-fceri |
| WO2024092031A1 (en) | 2022-10-25 | 2024-05-02 | Seismic Therapeutic, Inc. | VARIANT IgG FC POLYPEPTIDES AND USES THEREOF |
| AU2024297769A1 (en) | 2023-07-13 | 2026-03-05 | Inhibrx Biosciences, Inc. | Ige binding proteins and uses thereof |
| US12509529B2 (en) | 2024-05-17 | 2025-12-30 | Excellergy, Inc. | Antibodies and antibody fragments that bind IgE |
Family Cites Families (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US459004A (en) | 1891-09-08 | Box for steaming cops | ||
| US2228904A (en) | 1939-05-10 | 1941-01-14 | Bjorkman Hugo Leonard | Wrench |
| US5449760A (en) | 1987-12-31 | 1995-09-12 | Tanox Biosystems, Inc. | Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils |
| US5614611A (en) | 1987-12-31 | 1997-03-25 | Tanox Biosystems, Inc. | Humanized monoclonal antibodies binding to IgE-bearing B cells but not basophils |
| US5091313A (en) | 1988-08-05 | 1992-02-25 | Tanox Biosystems, Inc. | Antigenic epitopes of IgE present on B cell but not basophil surface |
| US5342924A (en) | 1987-12-31 | 1994-08-30 | Tanox Biosystems, Inc. | Extracellular segments of human ε immunoglobulin anchoring peptides and antibodies specific therefor |
| US5084468A (en) | 1988-08-11 | 1992-01-28 | Kyowa Hakko Kogyo Co., Ltd. | Dc-88a derivatives |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6797492B2 (en) | 1991-05-17 | 2004-09-28 | Merck & Co., Inc. | Method for reducing the immunogenicity of antibody variable domains |
| US6685939B2 (en) * | 1991-08-14 | 2004-02-03 | Genentech, Inc. | Method of preventing the onset of allergic disorders |
| US6329509B1 (en) | 1991-08-14 | 2001-12-11 | Genentech, Inc. | Anti-IgE antibodies |
| US5958708A (en) * | 1992-09-25 | 1999-09-28 | Novartis Corporation | Reshaped monoclonal antibodies against an immunoglobulin isotype |
| US6066718A (en) | 1992-09-25 | 2000-05-23 | Novartis Corporation | Reshaped monoclonal antibodies against an immunoglobulin isotype |
| US6037453A (en) * | 1995-03-15 | 2000-03-14 | Genentech, Inc. | Immunoglobulin variants |
| US20040197326A1 (en) * | 1995-07-27 | 2004-10-07 | Genentech, Inc. | Method for treatment of allergic asthma |
| US6172213B1 (en) | 1997-07-02 | 2001-01-09 | Genentech, Inc. | Anti-IgE antibodies and method of improving polypeptides |
| US5994511A (en) | 1997-07-02 | 1999-11-30 | Genentech, Inc. | Anti-IgE antibodies and methods of improving polypeptides |
| ES2434961T5 (es) | 1998-04-20 | 2018-01-18 | Roche Glycart Ag | Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo |
| US7118743B2 (en) | 1998-11-17 | 2006-10-10 | Tanox, Inc. | Bispecific molecules cross-linking ITIM and ITAM for therapy |
| EP1176195B1 (en) | 1999-04-09 | 2013-05-22 | Kyowa Hakko Kirin Co., Ltd. | Method for controlling the activity of immunologically functional molecule |
| AU7950400A (en) | 1999-10-19 | 2001-04-30 | Kyowa Hakko Kogyo Co. Ltd. | Process for producing polypeptide |
| US6736318B2 (en) | 2000-07-07 | 2004-05-18 | Amphenol-Tuchel Electronics Gmbh | Smart-card reader including mechanical locking means |
| JP2004502946A (ja) | 2000-07-10 | 2004-01-29 | ゼンコー | 改変された免疫原性を有するタンパク質ライブラリーを設計するためのタンパク質設計オートメーション |
| CN102311986B (zh) | 2000-10-06 | 2015-08-19 | 协和发酵麒麟株式会社 | 产生抗体组合物的细胞 |
| CA2424977C (en) | 2000-10-06 | 2008-03-18 | Kyowa Hakko Kogyo Co., Ltd. | Process for purifying antibody |
| JP2005500018A (ja) | 2001-04-02 | 2005-01-06 | アイデック ファーマスーティカルズ コーポレイション | GnTIIIと同時発現する組換え抗体 |
| US7117096B2 (en) | 2001-04-17 | 2006-10-03 | Abmaxis, Inc. | Structure-based selection and affinity maturation of antibody library |
| US20030157108A1 (en) | 2001-10-25 | 2003-08-21 | Genentech, Inc. | Glycoprotein compositions |
| US7662925B2 (en) | 2002-03-01 | 2010-02-16 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
| US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| US8188231B2 (en) | 2002-09-27 | 2012-05-29 | Xencor, Inc. | Optimized FC variants |
| US7317091B2 (en) | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
| DE10228103A1 (de) | 2002-06-24 | 2004-01-15 | Bayer Cropscience Ag | Fungizide Wirkstoffkombinationen |
| AU2003232081B2 (en) | 2002-07-03 | 2009-02-05 | Brandeis University | Central airway administration for systemic delivery of therapeutics |
| US20060235208A1 (en) | 2002-09-27 | 2006-10-19 | Xencor, Inc. | Fc variants with optimized properties |
| WO2004029207A2 (en) | 2002-09-27 | 2004-04-08 | Xencor Inc. | Optimized fc variants and methods for their generation |
| AU2004204942A1 (en) | 2003-01-08 | 2004-07-29 | Xencor, Inc | Novel proteins with altered immunogenicity |
| US7575893B2 (en) * | 2003-01-23 | 2009-08-18 | Genentech, Inc. | Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture |
| ES2575547T3 (es) | 2003-02-01 | 2016-06-29 | Tanox, Inc. | Anticuerpos anti-IgE de humano de alta afinidad |
| US20090010920A1 (en) | 2003-03-03 | 2009-01-08 | Xencor, Inc. | Fc Variants Having Decreased Affinity for FcyRIIb |
| US8388955B2 (en) * | 2003-03-03 | 2013-03-05 | Xencor, Inc. | Fc variants |
| US8084582B2 (en) | 2003-03-03 | 2011-12-27 | Xencor, Inc. | Optimized anti-CD20 monoclonal antibodies having Fc variants |
| US8101720B2 (en) | 2004-10-21 | 2012-01-24 | Xencor, Inc. | Immunoglobulin insertions, deletions and substitutions |
| JP2007512846A (ja) | 2003-12-04 | 2007-05-24 | ゼンコー・インコーポレイテッド | 増加した宿主ストリング含有量を有する変異体タンパク質の生成方法およびその組成物 |
| WO2005077981A2 (en) | 2003-12-22 | 2005-08-25 | Xencor, Inc. | Fc POLYPEPTIDES WITH NOVEL Fc LIGAND BINDING SITES |
| CA2566535A1 (en) | 2004-05-20 | 2006-05-11 | St. Mary's Hospital Nhs Trust | Ige-retargeting, function-altering molecules (erfam) for treatment of allergic diseases |
| CN103172731A (zh) | 2004-07-15 | 2013-06-26 | 赞科股份有限公司 | 优化的Fc变体 |
| US7655229B2 (en) | 2004-09-02 | 2010-02-02 | Chan Andrew C | Anti-FC-gamma RIIB receptor antibody and uses therefor |
| US20060148009A1 (en) | 2004-10-12 | 2006-07-06 | Xencor, Inc. | Prediction and assessment of immunogenicity |
| WO2006047350A2 (en) * | 2004-10-21 | 2006-05-04 | Xencor, Inc. | IgG IMMUNOGLOBULIN VARIANTS WITH OPTIMIZED EFFECTOR FUNCTION |
| US7301640B2 (en) | 2004-12-21 | 2007-11-27 | Honeywell International, Inc. | System and method of condensation reduction in an electrical unit |
| GB0502358D0 (en) * | 2005-02-04 | 2005-03-16 | Novartis Ag | Organic compounds |
| EP3479844B1 (en) | 2005-04-15 | 2023-11-22 | MacroGenics, Inc. | Covalent diabodies and uses thereof |
| US9963510B2 (en) | 2005-04-15 | 2018-05-08 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| US9284375B2 (en) | 2005-04-15 | 2016-03-15 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| AU2006299429B2 (en) | 2005-10-03 | 2012-02-23 | Xencor, Inc. | Fc variants with optimized Fc receptor binding properties |
| US7973136B2 (en) | 2005-10-06 | 2011-07-05 | Xencor, Inc. | Optimized anti-CD30 antibodies |
| WO2008123999A2 (en) * | 2007-04-02 | 2008-10-16 | Amgen Fremont Inc. | Anti-ige antibodies |
| DK2176298T3 (en) | 2007-05-30 | 2018-02-12 | Xencor Inc | Methods and compositions for inhibiting CD32B-expressing cells |
| PL2808343T3 (pl) | 2007-12-26 | 2019-11-29 | Xencor Inc | Warianty Fc ze zmienionym wiązaniem do FcRn |
| US8314213B2 (en) | 2008-04-18 | 2012-11-20 | Xencor, Inc. | Human equivalent monoclonal antibodies engineered from nonhuman variable regions |
| US20170247470A9 (en) * | 2008-09-17 | 2017-08-31 | Xencor, Inc. | Rapid clearance of antigen complexes using novel antibodies |
| WO2010033736A1 (en) | 2008-09-17 | 2010-03-25 | Xencor, Inc. | Novel compositons and methods for treating ige-mediated disorders |
| US10817851B2 (en) | 2009-12-23 | 2020-10-27 | Aristocrat Technologies Australia Pty Limited | System and method for cashless gaming |
| US20130129723A1 (en) | 2009-12-29 | 2013-05-23 | Emergent Product Development Seattle, Llc | Heterodimer Binding Proteins and Uses Thereof |
| US8362210B2 (en) | 2010-01-19 | 2013-01-29 | Xencor, Inc. | Antibody variants with enhanced complement activity |
| US20110189178A1 (en) | 2010-02-04 | 2011-08-04 | Xencor, Inc. | Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions |
| CA2797981C (en) | 2010-05-14 | 2019-04-23 | Rinat Neuroscience Corporation | Heterodimeric proteins and methods for producing and purifying them |
| US9146069B2 (en) | 2012-05-22 | 2015-09-29 | Haptech, Inc. | Method and apparatus for firearm recoil simulation |
| US11392902B2 (en) | 2017-06-06 | 2022-07-19 | United Parcel Service Of America, Inc. | Systems, methods, apparatuses and computer program products for providing notification of items for pickup and delivery |
| KR102185854B1 (ko) | 2017-09-09 | 2020-12-02 | 애플 인크. | 생체측정 인증의 구현 |
| CN115769181B (zh) | 2021-04-23 | 2025-10-10 | 京东方科技集团股份有限公司 | 一种解锁控制方法、装置、电子设备和计算机可读存储介质 |
-
2009
- 2009-09-17 WO PCT/US2009/057366 patent/WO2010033736A1/en not_active Ceased
- 2009-09-17 EP EP14167234.5A patent/EP2796469B1/en active Active
- 2009-09-17 SI SI200931501A patent/SI2853545T1/sl unknown
- 2009-09-17 PT PT141881029T patent/PT2853545T/pt unknown
- 2009-09-17 DK DK14167234.5T patent/DK2796469T3/da active
- 2009-09-17 ES ES09792678.6T patent/ES2499031T3/es active Active
- 2009-09-17 ES ES13185738T patent/ES2727677T3/es active Active
- 2009-09-17 ES ES19172636T patent/ES2927192T3/es active Active
- 2009-09-17 BR BRPI0918670A patent/BRPI0918670B8/pt active IP Right Grant
- 2009-09-17 PL PL14188102.9T patent/PL2853545T3/pl unknown
- 2009-09-17 EP EP09792678.6A patent/EP2331578B1/en active Active
- 2009-09-17 LT LTEP16170993.6T patent/LT3190128T/lt unknown
- 2009-09-17 EP EP13185738.5A patent/EP2703415B1/en active Active
- 2009-09-17 EP EP19172636.3A patent/EP3581588B1/en active Active
- 2009-09-17 ES ES14188102.9T patent/ES2589852T3/es active Active
- 2009-09-17 PT PT16170993T patent/PT3190128T/pt unknown
- 2009-09-17 EP EP16170993.6A patent/EP3190128B1/en active Active
- 2009-09-17 CN CN201510136642.9A patent/CN104961830B/zh active Active
- 2009-09-17 ES ES16170993T patent/ES2708842T3/es active Active
- 2009-09-17 JP JP2011527970A patent/JP5785493B2/ja active Active
- 2009-09-17 EP EP22175239.7A patent/EP4155323A1/en active Pending
- 2009-09-17 HU HUE14188102A patent/HUE029341T2/en unknown
- 2009-09-17 US US12/562,088 patent/US8435517B2/en active Active
- 2009-09-17 CA CA2736511A patent/CA2736511C/en active Active
- 2009-09-17 ES ES14167234T patent/ES2742419T3/es active Active
- 2009-09-17 SI SI200931927T patent/SI3190128T1/sl unknown
- 2009-09-17 DK DK16170993.6T patent/DK3190128T3/en active
- 2009-09-17 TR TR2018/21216T patent/TR201821216T4/tr unknown
- 2009-09-17 CN CN200980136559.4A patent/CN102292353B/zh active Active
- 2009-09-17 EP EP14188102.9A patent/EP2853545B8/en active Active
- 2009-09-17 KR KR1020117008155A patent/KR101783272B1/ko active Active
- 2009-09-17 HU HUE16170993A patent/HUE042901T2/hu unknown
- 2009-09-17 DK DK14188102.9T patent/DK2853545T3/en active
- 2009-09-17 AU AU2009293143A patent/AU2009293143C1/en active Active
- 2009-09-17 PL PL16170993T patent/PL3190128T3/pl unknown
- 2009-09-17 LT LTEP14188102.9T patent/LT2853545T/lt unknown
-
2013
- 2013-03-04 US US13/784,649 patent/US9062117B2/en active Active
- 2013-04-10 US US13/860,484 patent/US9540451B2/en active Active
- 2013-04-10 US US13/860,500 patent/US9617348B2/en active Active
-
2014
- 2014-10-08 US US14/510,054 patent/US9266966B2/en active Active
- 2014-10-08 US US14/510,037 patent/US9221916B2/en active Active
-
2015
- 2015-07-24 JP JP2015146285A patent/JP6178819B2/ja active Active
-
2016
- 2016-08-22 CY CY20161100825T patent/CY1118002T1/el unknown
- 2016-08-25 SM SM201600288T patent/SMT201600288B/it unknown
-
2017
- 2017-03-16 US US15/461,374 patent/US20170335013A1/en not_active Abandoned
-
2018
- 2018-12-17 HR HRP20182135TT patent/HRP20182135T1/hr unknown
-
2019
- 2019-01-24 CY CY20191100107T patent/CY1121204T1/el unknown
-
2020
- 2020-02-05 US US16/783,032 patent/US11566080B2/en active Active
-
2022
- 2022-12-22 US US18/087,157 patent/US12559572B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| LT2853545T (lt) | Antikūnai, specifiniai ige atžvilgiu | |
| IL276622A (en) | Antibody formulation | |
| ZA201102119B (en) | Improved antibody libraies | |
| GB0821100D0 (en) | Antibodies | |
| ZA201103027B (en) | Improved antibody molecules | |
| GB0903325D0 (en) | Antibody molecules | |
| SG10201401331TA (en) | Anti-siglec-15 antibody | |
| SG10201601279SA (en) | Monoclonal Antibody STRO-4 | |
| IL204537A0 (en) | Modified antibody constant region | |
| EP2138576A4 (en) | ANTI-CLAUDIN-4 ANTIBODY | |
| PL2146745T3 (pl) | Pięcioswoiste przeciwciało | |
| IL210903A0 (en) | Anit-il-12/il-23 antibodies | |
| IL211190A0 (en) | Novel antibody formulation | |
| IL207581A0 (en) | Anti-tyrp1 antibodies | |
| IL205073A0 (en) | Anti-bst2 antibody | |
| ZA201007976B (en) | Anti-pirb antibodies | |
| IL212900A0 (en) | Isoform specific anti-her4 antibodies | |
| GB0818356D0 (en) | Antibodies | |
| GB2473934B (en) | Anti-VEEV antibody | |
| GB0911770D0 (en) | Antibody | |
| EP2264071A4 (en) | ANTIBODY WITH AN IMMUNE-REINFORCING FUNCTION | |
| GB0817621D0 (en) | Antibody | |
| GB0817622D0 (en) | Antibody | |
| GB0819113D0 (en) | An antibody | |
| GB0806230D0 (en) | Antibodies |