SG10201401331TA - Anti-siglec-15 antibody - Google Patents

Anti-siglec-15 antibody

Info

Publication number
SG10201401331TA
SG10201401331TA SG10201401331TA SG10201401331TA SG10201401331TA SG 10201401331T A SG10201401331T A SG 10201401331TA SG 10201401331T A SG10201401331T A SG 10201401331TA SG 10201401331T A SG10201401331T A SG 10201401331TA SG 10201401331T A SG10201401331T A SG 10201401331TA
Authority
SG
Singapore
Prior art keywords
siglec
antibody
Prior art date
Application number
SG10201401331TA
Inventor
Hiruma Yoshiharu
Tsuda Eisuke
Takizawa Takeshi
Nakayama Makiko
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of SG10201401331TA publication Critical patent/SG10201401331TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG10201401331TA 2009-04-09 2010-04-07 Anti-siglec-15 antibody SG10201401331TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2009094613 2009-04-09

Publications (1)

Publication Number Publication Date
SG10201401331TA true SG10201401331TA (en) 2014-10-30

Family

ID=42936292

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2011047412A SG172419A1 (en) 2009-04-09 2010-04-07 Anti-siglec-15 antibody
SG10201401331TA SG10201401331TA (en) 2009-04-09 2010-04-07 Anti-siglec-15 antibody

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2011047412A SG172419A1 (en) 2009-04-09 2010-04-07 Anti-siglec-15 antibody

Country Status (19)

Country Link
US (3) US8575316B2 (en)
EP (2) EP2377932B1 (en)
JP (2) JP5653909B2 (en)
KR (1) KR101690340B1 (en)
CN (2) CN102272306B (en)
AU (2) AU2010235453B2 (en)
BR (1) BRPI1006134A2 (en)
CA (1) CA2750836C (en)
CO (1) CO6420359A2 (en)
ES (1) ES2840923T3 (en)
IL (2) IL213943A (en)
MX (2) MX2011007342A (en)
MY (1) MY152033A (en)
NZ (2) NZ605450A (en)
RU (2) RU2539790C2 (en)
SG (2) SG172419A1 (en)
TW (1) TWI468177B (en)
WO (1) WO2010117011A1 (en)
ZA (1) ZA201104545B (en)

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US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
US7989160B2 (en) 2006-02-13 2011-08-02 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in the process of bone remodeling
SI2206727T1 (en) * 2007-10-11 2015-06-30 Daiichi Sankyo Company, Limited ANTIBODY TARGETING OSTEOCLAST-RELATED PROTEIN Siglec-15
US8575316B2 (en) 2009-04-09 2013-11-05 Daiichi Sankyo Company, Limited Anti-Siglec-15 antibody
WO2012045481A2 (en) 2010-10-05 2012-04-12 Daiichi Sankyo Company, Limited Antibody targeting osteoclast-related protein siglec-15
ES2908046T3 (en) 2011-09-09 2022-04-27 Medimmune Ltd Anti-siglec-15 antibodies and uses thereof.
ES2660472T3 (en) * 2012-03-30 2018-03-22 Daiichi Sankyo Company, Limited Anti-Siglec-15 antibody modified with CDR
EP2832855A4 (en) * 2012-03-30 2016-02-24 Daiichi Sankyo Co Ltd Novel anti-siglec-15 antibody
ES2723885T3 (en) 2012-07-19 2019-09-03 Daiichi Sankyo Co Ltd Anti-Siglec-15 antibodies
MX2016003643A (en) 2013-09-30 2016-12-20 Daiichi Sankyo Co Ltd Anti-lps o11 antibody.
JP2017523148A (en) * 2014-06-18 2017-08-17 第一三共株式会社 Anti-Siglec-15 antibody for use in the treatment of osteogenesis imperfecta
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
ES2938186T3 (en) 2015-06-29 2023-04-05 Daiichi Sankyo Co Ltd Method for the selective manufacture of an antibody-drug conjugate
CN110035769A (en) * 2016-09-21 2019-07-19 奈斯科尔公司 For the antibody and its application method of SIGLEC-15
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
TWI782000B (en) 2017-03-30 2022-11-01 日商第一三共股份有限公司 Anti gpr20 antibodies, preparation method and application thereof
JP7181535B2 (en) * 2017-06-30 2022-12-01 国立大学法人北海道大学 Pediatric osteoporosis drug that does not cause growth disorders
SG11202000759XA (en) 2017-07-27 2020-02-27 Daiichi Sankyo Co Ltd Anti-cd147 antibody
KR20210018192A (en) 2018-05-31 2021-02-17 다이이찌 산쿄 가부시키가이샤 Anti-human TLR7 antibody
EP3831853A4 (en) 2018-07-27 2022-06-01 Daiichi Sankyo Company, Limited Protein recognizing drug moiety of antibody-drug conjugate
CN111378043B (en) * 2020-02-19 2021-02-09 南京医科大学 Human-mouse chimeric anti-Siglec-15 whole-molecule IgG with neutralization function and preparation method and application thereof
CN113817057B (en) * 2020-06-19 2024-02-20 盛禾(中国)生物制药有限公司 Anti-siglec 15 antibody and application thereof
CN112159475B (en) * 2020-10-10 2021-04-30 南京凯地生物科技有限公司 Siglec-15 monoclonal antibody and application thereof
CN114525256A (en) * 2020-10-30 2022-05-24 未来智人再生医学研究院(广州)有限公司 Pluripotent stem cell expressing Siglec-15 blocking substance or derivative thereof and application
WO2022228183A1 (en) * 2021-04-30 2022-11-03 杭州邦顺制药有限公司 Anti-siglec15 antibody, preparation method therefor and use thereof
CN113577283A (en) * 2021-07-19 2021-11-02 河北医科大学第三医院 Application of Siglec-15 inhibitor in preparation of medicines for preventing and treating giant cell tumor of bone
CN114807052A (en) * 2022-06-07 2022-07-29 江苏亲科生物研究中心有限公司 SIGLEC15 monoclonal antibody, preparation method and application thereof
WO2024040195A1 (en) 2022-08-17 2024-02-22 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering

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US8575316B2 (en) 2009-04-09 2013-11-05 Daiichi Sankyo Company, Limited Anti-Siglec-15 antibody

Also Published As

Publication number Publication date
RU2014147188A (en) 2016-06-10
KR101690340B1 (en) 2016-12-27
NZ593550A (en) 2013-11-29
JPWO2010117011A1 (en) 2012-10-18
NZ605450A (en) 2014-07-25
AU2010235453B2 (en) 2013-10-03
BRPI1006134A2 (en) 2016-02-23
CA2750836C (en) 2018-05-01
JP5653909B2 (en) 2015-01-14
KR20120034587A (en) 2012-04-12
TW201039852A (en) 2010-11-16
AU2013207589B2 (en) 2016-04-07
US20140065146A1 (en) 2014-03-06
IL252561A0 (en) 2017-07-31
US8575316B2 (en) 2013-11-05
AU2010235453A1 (en) 2011-07-28
MX2011007342A (en) 2011-07-21
IL213943A0 (en) 2011-07-31
CN102272306A (en) 2011-12-07
US9751944B2 (en) 2017-09-05
JP6210966B2 (en) 2017-10-11
RU2011128332A (en) 2013-01-20
IL252561B (en) 2019-02-28
EP2377932A4 (en) 2013-04-24
ZA201104545B (en) 2012-03-28
JP2015096510A (en) 2015-05-21
EP2377932A1 (en) 2011-10-19
CN106317224B (en) 2020-05-12
WO2010117011A1 (en) 2010-10-14
US20110268733A1 (en) 2011-11-03
CO6420359A2 (en) 2012-04-16
US9079959B2 (en) 2015-07-14
EP3699277A1 (en) 2020-08-26
MY152033A (en) 2014-08-15
CN102272306B (en) 2017-12-26
RU2014147188A3 (en) 2018-06-27
TWI468177B (en) 2015-01-11
RU2539790C2 (en) 2015-01-27
EP2377932B1 (en) 2020-11-18
SG172419A1 (en) 2011-07-28
CN106317224A (en) 2017-01-11
US20150299318A1 (en) 2015-10-22
CA2750836A1 (en) 2010-10-14
ES2840923T3 (en) 2021-07-07
MX343049B (en) 2016-10-21
IL213943A (en) 2017-06-29

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