DK3096756T3 - CRF1-receptorantagonister til behandling af medfødt adrenal hyperplasi - Google Patents
CRF1-receptorantagonister til behandling af medfødt adrenal hyperplasi Download PDFInfo
- Publication number
- DK3096756T3 DK3096756T3 DK15702917.4T DK15702917T DK3096756T3 DK 3096756 T3 DK3096756 T3 DK 3096756T3 DK 15702917 T DK15702917 T DK 15702917T DK 3096756 T3 DK3096756 T3 DK 3096756T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- receptor antagonists
- adrenal hyperplasia
- congenital adrenal
- crf1 receptor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461929941P | 2014-01-21 | 2014-01-21 | |
| US201461981033P | 2014-04-17 | 2014-04-17 | |
| US201462069155P | 2014-10-27 | 2014-10-27 | |
| PCT/US2015/012315 WO2015112642A1 (en) | 2014-01-21 | 2015-01-21 | Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3096756T3 true DK3096756T3 (da) | 2024-08-05 |
Family
ID=52450623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15702917.4T DK3096756T3 (da) | 2014-01-21 | 2015-01-21 | CRF1-receptorantagonister til behandling af medfødt adrenal hyperplasi |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US20170020877A1 (https=) |
| EP (2) | EP4450070A1 (https=) |
| JP (5) | JP6585625B2 (https=) |
| KR (2) | KR102258522B1 (https=) |
| CN (2) | CN106102740A (https=) |
| AU (4) | AU2015209452C1 (https=) |
| BR (1) | BR112016016975B1 (https=) |
| CA (2) | CA2936974A1 (https=) |
| DK (1) | DK3096756T3 (https=) |
| ES (1) | ES2984706T3 (https=) |
| FI (1) | FI3096756T3 (https=) |
| HR (1) | HRP20241046T1 (https=) |
| HU (1) | HUE068315T2 (https=) |
| IL (5) | IL296683B2 (https=) |
| LT (1) | LT3096756T (https=) |
| MX (3) | MX389004B (https=) |
| NZ (1) | NZ722122A (https=) |
| PL (1) | PL3096756T3 (https=) |
| PT (1) | PT3096756T (https=) |
| RS (1) | RS65839B1 (https=) |
| RU (1) | RU2718918C2 (https=) |
| SI (1) | SI3096756T1 (https=) |
| SM (1) | SMT202400361T1 (https=) |
| WO (1) | WO2015112642A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015112642A1 (en) | 2014-01-21 | 2015-07-30 | Neurocrine Biosciences, Inc. | Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia |
| CA2940242C (en) | 2014-02-20 | 2026-01-13 | H. Lundbeck A/S | Anti-acth antibodies and use thereof |
| EP3510029B1 (en) | 2016-09-07 | 2025-11-05 | The Regents of The University of California | Allosteric corticotropin-releasing factor receptor 1 (crfr1) antagonists that decrease p-tau and improve cognition |
| CN118845788A (zh) | 2017-08-14 | 2024-10-29 | 云杉生物科学公司 | 促肾上腺皮质激素释放因子受体拮抗剂 |
| EP4438124A3 (en) | 2018-04-27 | 2024-12-18 | Spruce Biosciences, Inc. | Methods for treating testicular and ovarian adrenal rest tumors |
| JP7532328B2 (ja) * | 2018-12-07 | 2024-08-13 | ニューロクライン バイオサイエンシーズ，インコーポレイテッド | 先天性副腎過形成を処置するためのｃｒｆ１受容体アンタゴニスト、その医薬製剤および固体形態 |
| CA3121920A1 (en) * | 2018-12-07 | 2020-06-11 | Neurocrine Biosciences, Inc. | Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia |
| TW202116324A (zh) * | 2019-07-19 | 2021-05-01 | 美商雲杉生物科技股份有限公司 | 治療先天性腎上腺增生之方法 |
| JP7623365B2 (ja) * | 2019-09-27 | 2025-01-28 | ニューロクライン バイオサイエンシーズ，インコーポレイテッド | Ｃｒｆ受容体アンタゴニストおよび使用方法 |
| IL298901A (en) * | 2020-06-10 | 2023-02-01 | Neurocrine Biosciences Inc | A CRF1 receptor antagonist for the treatment of congenital adrenal hyperplasia |
| BR112023002497A2 (pt) * | 2020-08-12 | 2023-05-02 | Spruce Biosciences Inc | Métodos e composições para tratamento da síndrome dos ovários policísticos |
| MD20210019A2 (ro) | 2021-04-12 | 2022-10-31 | Максим МАСЮТИН | Metodă de tratament a hiperplaziei suprarenale congenitale, cauzate de deficit de 21-hidroxilază cu debut tardiv prin regimul de glucocorticoizi adaptat individual |
| US11708372B2 (en) | 2021-11-19 | 2023-07-25 | Spruce Biosciences, Inc. | Crystalline composition of tildacerfont and methods of use and preparation thereof |
Family Cites Families (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4949582B1 (https=) | 1969-01-20 | 1974-12-27 | ||
| US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
| FR2692893B1 (fr) | 1992-06-24 | 1994-09-02 | Sanofi Elf | Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
| US6664261B2 (en) | 1996-02-07 | 2003-12-16 | Neurocrine Biosciences, Inc. | Pyrazolopyrimidines as CRF receptor antagonists |
| TW477787B (en) | 1996-08-27 | 2002-03-01 | Pfizer | Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same |
| US6159980A (en) | 1996-09-16 | 2000-12-12 | Dupont Pharmaceuticals Company | Pyrazinones and triazinones and their derivatives thereof |
| FR2754258B1 (fr) | 1996-10-08 | 1998-12-31 | Sanofi Sa | Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
| ES2207834T3 (es) | 1997-04-22 | 2004-06-01 | Janssen Pharmaceutica N.V. | Quino- y quinazolinas antagonistas del crf. |
| AU9021598A (en) | 1997-08-22 | 1999-03-16 | Du Pont Pharmaceuticals Company | Nitrogen substituted imidazo{4,5-c}pyrazoles as corticotropin relea sing hormone antagonists |
| US6531475B1 (en) | 1998-11-12 | 2003-03-11 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
| WO2000059888A1 (en) | 1999-04-02 | 2000-10-12 | Neurogen Corporation | N-benzimidazolylmethyl- and n-indolylmethyl-benzamides and their use as crf modulators |
| FR2796380B3 (fr) | 1999-07-15 | 2001-08-17 | Sanofi Synthelabo | Nouveaux derives d'aminothiazoles, leur preparation et les compositions pharmaceutiques les contenant |
| FR2802530B1 (fr) | 1999-12-17 | 2002-02-22 | Sanofi Synthelabo | Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant |
| WO2003006015A1 (en) | 2001-07-13 | 2003-01-23 | Bristol-Myers Squibb Pharma Company | Substituted thiazoles and oxazoles as corticotropin releasing hormone ligands |
| WO2005079807A1 (en) | 2004-02-13 | 2005-09-01 | Pfizer Products Inc. | Therapeutic combinations of atypical antipsychotics with corticotropin releasing factor antagonists |
| WO2006124047A2 (en) | 2004-08-13 | 2006-11-23 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
| DE602005014375D1 (de) | 2004-10-19 | 2009-06-18 | Neurocrine Biosciences Inc | Crf-rezeptor-antagonisten und zugehörige verfahren |
| GB0519957D0 (en) | 2005-09-30 | 2005-11-09 | Sb Pharmco Inc | Chemical compound |
| AU2006227300B2 (en) | 2005-03-21 | 2012-02-02 | Eli Lilly And Company | Imidazopyridazine compounds |
| WO2006107784A1 (en) | 2005-04-05 | 2006-10-12 | Eli Lilly And Company | Imidazopyridazine compounds |
| TWI370820B (en) | 2005-04-27 | 2012-08-21 | Takeda Pharmaceutical | Fused heterocyclic compounds |
| EP1903045A1 (en) | 2005-05-27 | 2008-03-26 | Mitsubishi Tanabe Pharma Corporation | Pyrazolopyrimidine derivative |
| JP5377968B2 (ja) | 2005-11-10 | 2013-12-25 | トポターゲット ユーケー リミテッド | 癌治療のために単独で用いるまたは化学療法薬と併用するヒストンデアセチラーゼ（ｈｄａｃ）阻害剤 |
| EP1961745A1 (en) | 2005-12-12 | 2008-08-27 | Ono Pharmaceutical Co., Ltd. | Bicyclic heterocyclic compound |
| EP1961754A4 (en) | 2005-12-15 | 2009-11-11 | Ono Pharmaceutical Co | BICYCLIC HETEROCYCLIC COMPOUND |
| ES2435793T3 (es) | 2006-02-07 | 2013-12-23 | Phenoquest Ag | Procedimientos para el tratamiento de trastornos afectivos |
| EP1834641A1 (en) | 2006-03-16 | 2007-09-19 | Sanofi-Aventis | Use of CRF1 receptor antagonists for preparing a drug for treating metabolic syndrome and/or obesity and/or dyslipoproteinemia |
| US20090306137A1 (en) | 2006-05-22 | 2009-12-10 | Wolfgang Curt D | Treatment for depressive disorders |
| EP2094709B1 (en) * | 2006-09-20 | 2010-09-15 | Eli Lilly And Company | Thiazole pyrazolopyrimidines as crf1 receptor antagonists |
| AU2007297481B2 (en) | 2006-09-20 | 2012-03-08 | Eli Lilly And Company | Thiophene pyrazolopyrimidine compounds |
| US20100056515A1 (en) | 2006-10-25 | 2010-03-04 | Kazuyoshi Aso | Benzimidazole compounds |
| JP2010514672A (ja) | 2006-12-29 | 2010-05-06 | 武田薬品工業株式会社 | Ｃｒｆアンタゴニスト活性を有する縮合複素環化合物 |
| WO2008083070A1 (en) | 2006-12-29 | 2008-07-10 | Neurogen Corporation | Crf1 receptor ligands comprising fused bicyclic heteroaryl moieties |
| TW200902019A (en) | 2007-04-26 | 2009-01-16 | Ono Pharmaceutical Co | Dicyclic heterocyclic compound |
| WO2009008552A1 (en) | 2007-07-11 | 2009-01-15 | Taisho Pharmaceutical Co., Ltd. | 8-aryl-4-alkylpyrrolo[2,3,4-de]quinolin-5(4h)-one and 8-aryl-4-alkyl-4,5-dihydropyrrolo[2,3,4-de]quinolin-5-ol derivatives |
| WO2009144632A1 (en) | 2008-05-30 | 2009-12-03 | Pfizer Limited | Novel compounds |
| US7932256B2 (en) | 2008-07-31 | 2011-04-26 | Bristol-Myers Squibb Company | (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile: a pyrazinone modulator of corticotropin-releasing factor receptor activity |
| CN102105149A (zh) | 2008-07-31 | 2011-06-22 | 百时美施贵宝公司 | 作为促肾上腺皮质激素释放因子受体活性调节剂的取代的氨基甲酸酯衍生物 |
| US7994203B2 (en) | 2008-08-06 | 2011-08-09 | Novartis Ag | Organic compounds |
| US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
| CN102245117B (zh) | 2008-11-03 | 2014-04-16 | 斯恩蒂斯有限公司 | 可调节的杆组件 |
| US8551996B2 (en) | 2009-02-20 | 2013-10-08 | Emory University | Compounds, compositions, methods of synthesis, and methods of treatment |
| HUP0900267A2 (en) | 2009-04-30 | 2011-03-28 | Sanofi Aventis | Process for preparing of thiazole amines and intermediates thereof |
| AR078521A1 (es) | 2009-10-08 | 2011-11-16 | Eisai R&D Man Co Ltd | Compuesto pirazolotiazol |
| JPWO2011043387A1 (ja) | 2009-10-08 | 2013-03-04 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピラゾロオキサゾール化合物 |
| WO2011092290A1 (en) | 2010-02-01 | 2011-08-04 | Novartis Ag | Pyrazolo[5,1b]oxazole derivatives as crf-1 receptor antagonists |
| AR080056A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
| EP2531490B1 (en) | 2010-02-02 | 2014-10-15 | Novartis AG | Cyclohexyl amide derivatives as crf receptor antagonists |
| SG10201912111TA (en) | 2012-04-13 | 2020-02-27 | Epizyme Inc | Combination therapy for treating cancer |
| EP2841595A2 (en) * | 2012-04-23 | 2015-03-04 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Genetic predictors of response to treatment with crhr1 antagonists |
| HK1207304A1 (en) | 2012-04-23 | 2016-01-29 | Hmnc Value Gmbh | Crhr1 antagonists for use in the treatment of patients having crh overactivity |
| WO2015112642A1 (en) | 2014-01-21 | 2015-07-30 | Neurocrine Biosciences, Inc. | Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia |
| WO2016065177A1 (en) | 2014-10-22 | 2016-04-28 | The Trustees Of The University Of Pennsylvania | Method of treating depression and other stress related disorders |
| CA2974540C (en) | 2015-02-06 | 2023-09-26 | Neurocrine Biosciences, Inc. | [9,10-dimethoxy-3-(2-methylpropyl)-1h,2h,3h,4h,6h,7h,11bh-pyrido-[2,1-a]isoquinolin-2-yl]methanol and compounds, compositions and methods relating thereto |
| WO2016156576A1 (en) | 2015-04-02 | 2016-10-06 | Hmnc Value Gmbh | Method of treatment using genetic predictors of a response to treatment with crhr1 antagonists |
| WO2018012066A1 (ja) * | 2016-07-14 | 2018-01-18 | 株式会社コナミデジタルエンタテインメント | ゲームシステム、端末装置及びプログラム |
| JP7595413B2 (ja) | 2016-11-30 | 2024-12-06 | ケース ウエスタン リザーブ ユニバーシティ | １５－ｐｇｄｈ阻害剤とコルチコステロイドおよび／またはｔｎｆ阻害剤との組み合わせならびにその使用 |
| WO2018219804A1 (en) | 2017-06-02 | 2018-12-06 | Bayer Pharma Aktiengesellschaft | Self-microemulsifying drug delivery systems |
| CN118845788A (zh) | 2017-08-14 | 2024-10-29 | 云杉生物科学公司 | 促肾上腺皮质激素释放因子受体拮抗剂 |
| EA202090321A1 (ru) | 2017-08-14 | 2020-09-24 | Спрюс Биосайнсес, Инк. | Антагонисты рецептора кортикотропин-рилизинг фактора |
| EP4438124A3 (en) * | 2018-04-27 | 2024-12-18 | Spruce Biosciences, Inc. | Methods for treating testicular and ovarian adrenal rest tumors |
| CA3121920A1 (en) | 2018-12-07 | 2020-06-11 | Neurocrine Biosciences, Inc. | Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia |
| TW202116324A (zh) | 2019-07-19 | 2021-05-01 | 美商雲杉生物科技股份有限公司 | 治療先天性腎上腺增生之方法 |
| JP7623365B2 (ja) | 2019-09-27 | 2025-01-28 | ニューロクライン バイオサイエンシーズ，インコーポレイテッド | Ｃｒｆ受容体アンタゴニストおよび使用方法 |
| WO2021113263A1 (en) | 2019-12-04 | 2021-06-10 | Neurocrine Biosciences, Inc. | Crf receptor antagonists and methods of use |
| IL298901A (en) | 2020-06-10 | 2023-02-01 | Neurocrine Biosciences Inc | A CRF1 receptor antagonist for the treatment of congenital adrenal hyperplasia |
| JP2023540223A (ja) | 2020-08-26 | 2023-09-22 | ニューロクライン バイオサイエンシーズ，インコーポレイテッド | Ｃｒｆ受容体アンタゴニストおよび使用方法 |
-
2015
- 2015-01-21 WO PCT/US2015/012315 patent/WO2015112642A1/en not_active Ceased
- 2015-01-21 MX MX2016009499A patent/MX389004B/es unknown
- 2015-01-21 PT PT157029174T patent/PT3096756T/pt unknown
- 2015-01-21 IL IL296683A patent/IL296683B2/en unknown
- 2015-01-21 ES ES15702917T patent/ES2984706T3/es active Active
- 2015-01-21 CA CA2936974A patent/CA2936974A1/en active Pending
- 2015-01-21 AU AU2015209452A patent/AU2015209452C1/en active Active
- 2015-01-21 HU HUE15702917A patent/HUE068315T2/hu unknown
- 2015-01-21 CN CN201580005270.4A patent/CN106102740A/zh active Pending
- 2015-01-21 CA CA3155599A patent/CA3155599A1/en active Pending
- 2015-01-21 US US15/113,362 patent/US20170020877A1/en not_active Abandoned
- 2015-01-21 IL IL317035A patent/IL317035A/en unknown
- 2015-01-21 BR BR112016016975-1A patent/BR112016016975B1/pt active IP Right Grant
- 2015-01-21 PL PL15702917.4T patent/PL3096756T3/pl unknown
- 2015-01-21 JP JP2016565135A patent/JP6585625B2/ja active Active
- 2015-01-21 RU RU2016133972A patent/RU2718918C2/ru active
- 2015-01-21 EP EP24174933.2A patent/EP4450070A1/en active Pending
- 2015-01-21 EP EP15702917.4A patent/EP3096756B1/en active Active
- 2015-01-21 IL IL304134A patent/IL304134B2/en unknown
- 2015-01-21 KR KR1020167022375A patent/KR102258522B1/ko active Active
- 2015-01-21 RS RS20240910A patent/RS65839B1/sr unknown
- 2015-01-21 CN CN202010134003.XA patent/CN111228274A/zh active Pending
- 2015-01-21 KR KR1020217015795A patent/KR20210064407A/ko not_active Ceased
- 2015-01-21 HR HRP20241046TT patent/HRP20241046T1/hr unknown
- 2015-01-21 FI FIEP15702917.4T patent/FI3096756T3/fi active
- 2015-01-21 NZ NZ722122A patent/NZ722122A/en unknown
- 2015-01-21 SM SM20240361T patent/SMT202400361T1/it unknown
- 2015-01-21 SI SI201532025T patent/SI3096756T1/sl unknown
- 2015-01-21 DK DK15702917.4T patent/DK3096756T3/da active
- 2015-01-21 LT LTEPPCT/US2015/012315T patent/LT3096756T/lt unknown
-
2016
- 2016-07-14 IL IL246783A patent/IL246783B/en unknown
- 2016-07-21 MX MX2022000080A patent/MX2022000080A/es unknown
- 2016-07-21 MX MX2021012539A patent/MX2021012539A/es unknown
-
2018
- 2018-12-20 US US16/227,127 patent/US10905690B2/en active Active
-
2019
- 2019-03-11 JP JP2019043466A patent/JP6936825B2/ja active Active
-
2020
- 2020-06-09 JP JP2020099865A patent/JP7104743B2/ja active Active
- 2020-07-20 AU AU2020207774A patent/AU2020207774B2/en active Active
- 2020-10-20 US US17/074,845 patent/US11730739B2/en active Active
-
2021
- 2021-08-04 US US17/393,553 patent/US11311544B2/en active Active
- 2021-09-29 IL IL286782A patent/IL286782A/en unknown
- 2021-11-12 JP JP2021184620A patent/JP2022010260A/ja not_active Withdrawn
-
2022
- 2022-10-31 AU AU2022263460A patent/AU2022263460B2/en active Active
-
2023
- 2023-07-14 US US18/222,011 patent/US20240058342A1/en active Pending
-
2024
- 2024-05-15 JP JP2024079330A patent/JP2024098001A/ja active Pending
- 2024-09-17 AU AU2024219813A patent/AU2024219813A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3096756T3 (da) | CRF1-receptorantagonister til behandling af medfødt adrenal hyperplasi | |
| PL3660004T3 (pl) | Związki i sposoby do ukierunkowanej degradacji receptora androgenowego | |
| DK3300500T3 (da) | Triazolagonister af apj-receptoren | |
| DK3473783T3 (da) | Fremgangsmåde til fremstilling af gulvplader | |
| DK3192902T3 (da) | Fremgangsmåde til fremstilling af graphenholdige viscosefibre | |
| DK3718507T3 (da) | Anordninger til behandling af nedre ekstremitetsvaskulatur | |
| DK3286311T3 (da) | Fremgangsmåde til behandling af maligniteter | |
| DK3466432T3 (da) | Fremgangsmåder til behandling af pulmonale non-tuberkuløse mykobakterielle infektioner | |
| DK3521282T3 (da) | Quinazolinderivater anvendt til behandling af hiv | |
| IL261461B (en) | Methods of treating depression using orexin-2 receptor antagonists | |
| DK3096741T3 (da) | Fremgangsmåde til fremstillingen af hybridosomer | |
| EP3280707C0 (en) | BICYCLIC QUINAZOLINONE DERIVATIVES | |
| DK3174858T3 (da) | Fremgangsmåde til fremstilling af pyrazoler | |
| DK3143037T3 (da) | Alpha4beta7-integrin-thioether-peptidantagonister | |
| DK3297631T3 (da) | NK-1/NK-3-receptorantagonist til behandling af hedeture | |
| DK3157534T3 (da) | Acetylcholinesterasehæmmere til behandling af dermatologiske tilstande | |
| DK3280710T3 (da) | Fremgangsmåde til fremstilling af androgenreceptorantagonister og mellemprodukter deraf | |
| EP3523315A4 (en) | INHIBITORS OF THE GLUCOCORTICOID RECEPTOR | |
| DK3212637T3 (da) | Dopamin-d3-receptorantagonistforbindelser | |
| EP3394078A4 (en) | INHIBITORS OF THE GLUCOCORTICIDE RECEPTOR | |
| DK3331610T3 (da) | Midler til anvendelse til behandling af gliom | |
| DK3511418T3 (da) | Fremgangsmåde til nedbrydning af mannanholdige celluloseholdige materialer | |
| EP3394079A4 (en) | INHIBITORS OF GLUCOCORTICOIDREZEPTORS | |
| EP3350167A4 (en) | Androgen receptor Antagonist | |
| DK3334721T3 (da) | Cgrp-receptorantagonister |