DK3016970T3 - O-mannosyltransferase-defekte filamentøse svampeceller og fremgangsmåder til anvendelse deraf - Google Patents
O-mannosyltransferase-defekte filamentøse svampeceller og fremgangsmåder til anvendelse deraf Download PDFInfo
- Publication number
- DK3016970T3 DK3016970T3 DK14734515.1T DK14734515T DK3016970T3 DK 3016970 T3 DK3016970 T3 DK 3016970T3 DK 14734515 T DK14734515 T DK 14734515T DK 3016970 T3 DK3016970 T3 DK 3016970T3
- Authority
- DK
- Denmark
- Prior art keywords
- mannosyltransferase
- defected
- filaments
- methods
- spot cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01109—Dolichyl-phosphate-mannose-protein mannosyltransferase (2.4.1.109)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13175141 | 2013-07-04 | ||
PCT/EP2014/064248 WO2015001049A1 (en) | 2013-07-04 | 2014-07-03 | O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3016970T3 true DK3016970T3 (da) | 2019-06-24 |
Family
ID=48740957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14734515.1T DK3016970T3 (da) | 2013-07-04 | 2014-07-03 | O-mannosyltransferase-defekte filamentøse svampeceller og fremgangsmåder til anvendelse deraf |
Country Status (15)
Country | Link |
---|---|
US (4) | US20160376570A1 (da) |
EP (1) | EP3016970B1 (da) |
KR (1) | KR102111078B1 (da) |
CN (1) | CN105492457A (da) |
BR (1) | BR112015032695A2 (da) |
CA (1) | CA2916594C (da) |
DK (1) | DK3016970T3 (da) |
ES (1) | ES2739280T3 (da) |
HR (1) | HRP20191069T1 (da) |
MX (1) | MX364532B (da) |
PL (1) | PL3016970T3 (da) |
RU (1) | RU2016103373A (da) |
SG (1) | SG11201510814YA (da) |
SI (1) | SI3016970T1 (da) |
WO (1) | WO2015001049A1 (da) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10513724B2 (en) | 2014-07-21 | 2019-12-24 | Glykos Finland Oy | Production of glycoproteins with mammalian-like N-glycans in filamentous fungi |
US20210388310A1 (en) * | 2018-09-20 | 2021-12-16 | Perfect Day, Inc. | Methods and compositions for producing homokaryotic filamentous fungal cells |
US20220025423A1 (en) * | 2018-11-28 | 2022-01-27 | Novozymes A/S | Modified Filamentous Fungal Host Cells |
CN110885810B (zh) * | 2019-12-16 | 2021-03-23 | 华中农业大学 | 一种利用真核发酵制备得到的抑菌蛋白酶CmYC1及其应用 |
CN115976033B (zh) * | 2022-12-14 | 2024-05-17 | 西南大学 | 瓜实蝇tssk1和tssk3基因及其应用 |
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US5958727A (en) | 1996-09-13 | 1999-09-28 | Novo Nordisk Biotech, Inc | Methods for modifying the production of a polypeptide |
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GB9902000D0 (en) | 1999-01-30 | 1999-03-17 | Delta Biotechnology Ltd | Process |
GB0021421D0 (en) | 2000-08-31 | 2000-10-18 | Oxford Glycosciences Uk Ltd | Compounds |
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WO2005003296A2 (en) | 2003-01-22 | 2005-01-13 | Human Genome Sciences, Inc. | Albumin fusion proteins |
NZ540743A (en) | 2002-12-20 | 2008-06-30 | Unilever Plc | Preparation of antifreeze protein |
ES2380022T3 (es) | 2003-12-03 | 2012-05-07 | Monika KRÖZ | Proteínas de fusión a interleucina-11 |
PL1729795T3 (pl) | 2004-02-09 | 2016-08-31 | Human Genome Sciences Inc | Białka fuzyjne albuminy |
WO2006036817A2 (en) | 2004-09-24 | 2006-04-06 | Microbia, Inc. | Fungal variants and uses thereof |
CN101292024B (zh) * | 2005-10-17 | 2012-04-18 | 诺维信公司 | 用于表达抗体的真菌突变体的用途 |
US8206949B2 (en) | 2005-11-15 | 2012-06-26 | Glycofi, Inc. | Production of glycoproteins with reduced O-glycosylation |
WO2007132949A1 (ja) | 2006-05-16 | 2007-11-22 | National Institute Of Advanced Industrial Science And Technology | タンパク質の高分泌生産方法 |
EP2102366A4 (en) | 2006-12-10 | 2010-01-27 | Dyadic International Inc | EXPRESSION AND HIGH-DROP SCREENING OF COMPLEX EXPRESSED DNA LIBRARIES IN FADENED MUSHROOMS |
GB0711424D0 (en) | 2007-06-13 | 2007-07-25 | Novozymes Delta Ltd | Recombinant transferrin mutants |
CA2695830A1 (en) | 2007-08-08 | 2009-02-12 | Novozymes Biopharma Dk A/S | Transferrin variants and conjugates |
CN101945998B (zh) * | 2008-02-20 | 2013-09-18 | 格利科菲公司 | 用于蛋白生产的载体和酵母菌株 |
US20090253173A1 (en) * | 2008-04-08 | 2009-10-08 | Danisco Us Inc., Genencor Division | Filamentous fungi with inactivated protease genes for altered protein production |
AU2009249314A1 (en) | 2008-05-20 | 2009-11-26 | Merck Sharp & Dohme Corp. | Efficient production of heterologous proteins using mannosyl transferase inhibitors |
MX2011001706A (es) * | 2008-08-12 | 2011-03-24 | Glycofi Inc | Vectores mejorados y cepas de levadura para produccion de proteina: sobreexpresion de ca2+ atpasa. |
WO2010034708A1 (en) | 2008-09-23 | 2010-04-01 | Unilever Plc | A polynucleotide expression cassette |
JP5936112B2 (ja) | 2009-02-11 | 2016-06-15 | アルブミディクス アクティーゼルスカブ | アルブミン変異体及び複合体 |
WO2010128142A1 (en) | 2009-05-07 | 2010-11-11 | Novozymes Biopharma Dk A/S | Method for purifying albumin |
WO2010128145A1 (en) | 2009-05-07 | 2010-11-11 | Novozymes Biopharma Dk A/S | Method of controlling o-linked glycosylation of antibodies |
US8440456B2 (en) | 2009-05-22 | 2013-05-14 | Vib, Vzw | Nucleic acids of Pichia pastoris and use thereof for recombinant production of proteins |
CN104031961A (zh) | 2009-10-16 | 2014-09-10 | 默沙东公司 | 生产成熟的人促红细胞生成素的方法以及包含获自该方法的人促红细胞生成素的组合物 |
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EP2539430B1 (en) * | 2010-02-24 | 2016-09-14 | Merck Sharp & Dohme Corp. | Method for increasing n-glycosylation site occupancy on therapeutic glycoproteins produced in pichia pastoris |
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WO2013074598A1 (en) | 2011-11-18 | 2013-05-23 | Merck Sharp & Dohme Corp. | Fc CONTAINING POLYPEPTIDES HAVING INCREASED ANTI-INFLAMMATORY PROPERTIES AND INCREASED FcRN BINDING |
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-
2014
- 2014-07-03 SI SI201431239T patent/SI3016970T1/sl unknown
- 2014-07-03 DK DK14734515.1T patent/DK3016970T3/da active
- 2014-07-03 BR BR112015032695A patent/BR112015032695A2/pt not_active Application Discontinuation
- 2014-07-03 MX MX2016000128A patent/MX364532B/es active IP Right Grant
- 2014-07-03 WO PCT/EP2014/064248 patent/WO2015001049A1/en active Application Filing
- 2014-07-03 US US14/902,492 patent/US20160376570A1/en not_active Abandoned
- 2014-07-03 PL PL14734515T patent/PL3016970T3/pl unknown
- 2014-07-03 RU RU2016103373A patent/RU2016103373A/ru not_active Application Discontinuation
- 2014-07-03 KR KR1020157036975A patent/KR102111078B1/ko active IP Right Grant
- 2014-07-03 CN CN201480048205.5A patent/CN105492457A/zh active Pending
- 2014-07-03 ES ES14734515T patent/ES2739280T3/es active Active
- 2014-07-03 EP EP14734515.1A patent/EP3016970B1/en active Active
- 2014-07-03 SG SG11201510814YA patent/SG11201510814YA/en unknown
- 2014-07-03 CA CA2916594A patent/CA2916594C/en active Active
-
2018
- 2018-09-07 US US16/124,679 patent/US10724013B2/en active Active
-
2019
- 2019-06-13 HR HRP20191069 patent/HRP20191069T1/hr unknown
-
2020
- 2020-06-15 US US16/901,175 patent/US20200362319A1/en not_active Abandoned
-
2022
- 2022-03-21 US US17/699,302 patent/US20220213451A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
SI3016970T1 (sl) | 2019-08-30 |
RU2016103373A3 (da) | 2018-03-26 |
BR112015032695A2 (pt) | 2017-10-24 |
ES2739280T3 (es) | 2020-01-30 |
US20200040314A1 (en) | 2020-02-06 |
EP3016970A1 (en) | 2016-05-11 |
US20160376570A1 (en) | 2016-12-29 |
PL3016970T3 (pl) | 2019-09-30 |
HRP20191069T1 (hr) | 2019-11-01 |
US20200362319A1 (en) | 2020-11-19 |
KR20160030127A (ko) | 2016-03-16 |
MX2016000128A (es) | 2016-03-01 |
US20220213451A1 (en) | 2022-07-07 |
WO2015001049A1 (en) | 2015-01-08 |
CA2916594C (en) | 2020-03-10 |
MX364532B (es) | 2019-04-29 |
EP3016970B1 (en) | 2019-05-22 |
US10724013B2 (en) | 2020-07-28 |
RU2016103373A (ru) | 2017-08-10 |
SG11201510814YA (en) | 2016-01-28 |
CA2916594A1 (en) | 2015-01-08 |
KR102111078B1 (ko) | 2020-05-18 |
CN105492457A (zh) | 2016-04-13 |
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