SG11201510814YA - O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof - Google Patents

O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof

Info

Publication number
SG11201510814YA
SG11201510814YA SG11201510814YA SG11201510814YA SG11201510814YA SG 11201510814Y A SG11201510814Y A SG 11201510814YA SG 11201510814Y A SG11201510814Y A SG 11201510814YA SG 11201510814Y A SG11201510814Y A SG 11201510814YA SG 11201510814Y A SG11201510814Y A SG 11201510814YA
Authority
SG
Singapore
Prior art keywords
mannosyltransferase
methods
filamentous fungal
fungal cells
deficient filamentous
Prior art date
Application number
SG11201510814YA
Inventor
Jari Natunen
Jukka Hiltunen
Anne Huuskonen
Markku Saloheimo
Christian Ostermeier
Benjamin Patrick Sommer
Ramon Wahl
Original Assignee
Novartis Ag
Glykos Finland Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48740957&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201510814Y(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Glykos Finland Oy filed Critical Novartis Ag
Publication of SG11201510814YA publication Critical patent/SG11201510814YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01109—Dolichyl-phosphate-mannose-protein mannosyltransferase (2.4.1.109)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
SG11201510814YA 2013-07-04 2014-07-03 O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof SG11201510814YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13175141 2013-07-04
PCT/EP2014/064248 WO2015001049A1 (en) 2013-07-04 2014-07-03 O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof

Publications (1)

Publication Number Publication Date
SG11201510814YA true SG11201510814YA (en) 2016-01-28

Family

ID=48740957

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201510814YA SG11201510814YA (en) 2013-07-04 2014-07-03 O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof

Country Status (15)

Country Link
US (4) US20160376570A1 (en)
EP (1) EP3016970B1 (en)
KR (1) KR102111078B1 (en)
CN (1) CN105492457A (en)
BR (1) BR112015032695A2 (en)
CA (1) CA2916594C (en)
DK (1) DK3016970T3 (en)
ES (1) ES2739280T3 (en)
HR (1) HRP20191069T1 (en)
MX (1) MX364532B (en)
PL (1) PL3016970T3 (en)
RU (1) RU2016103373A (en)
SG (1) SG11201510814YA (en)
SI (1) SI3016970T1 (en)
WO (1) WO2015001049A1 (en)

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* Cited by examiner, † Cited by third party
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CA2954974A1 (en) 2014-07-21 2016-01-28 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
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CA3121271A1 (en) * 2018-11-28 2020-06-04 Novozymes A/S Modified filamentous fungal host cells
CN110885810B (en) * 2019-12-16 2021-03-23 华中农业大学 Bacteriostatic protease CmYC1 prepared by eukaryotic fermentation and application thereof

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Also Published As

Publication number Publication date
HRP20191069T1 (en) 2019-11-01
DK3016970T3 (en) 2019-06-24
RU2016103373A3 (en) 2018-03-26
US20200040314A1 (en) 2020-02-06
EP3016970A1 (en) 2016-05-11
US10724013B2 (en) 2020-07-28
BR112015032695A2 (en) 2017-10-24
WO2015001049A1 (en) 2015-01-08
EP3016970B1 (en) 2019-05-22
KR20160030127A (en) 2016-03-16
US20160376570A1 (en) 2016-12-29
US20220213451A1 (en) 2022-07-07
ES2739280T3 (en) 2020-01-30
KR102111078B1 (en) 2020-05-18
RU2016103373A (en) 2017-08-10
CA2916594A1 (en) 2015-01-08
MX2016000128A (en) 2016-03-01
PL3016970T3 (en) 2019-09-30
US20200362319A1 (en) 2020-11-19
CA2916594C (en) 2020-03-10
CN105492457A (en) 2016-04-13
SI3016970T1 (en) 2019-08-30
MX364532B (en) 2019-04-29

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