DK2913059T3 - Hidtil ukendt fremgangsmåde til behandling af rygmarvsskade ved anvendelse af hmgb1-fragment - Google Patents
Hidtil ukendt fremgangsmåde til behandling af rygmarvsskade ved anvendelse af hmgb1-fragment Download PDFInfo
- Publication number
- DK2913059T3 DK2913059T3 DK13849823.3T DK13849823T DK2913059T3 DK 2913059 T3 DK2913059 T3 DK 2913059T3 DK 13849823 T DK13849823 T DK 13849823T DK 2913059 T3 DK2913059 T3 DK 2913059T3
- Authority
- DK
- Denmark
- Prior art keywords
- cells
- bone marrow
- hmgb1
- fragment
- peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Claims (3)
1. Farmaceutisk sammensætning til anvendelse til behandling af skade på rygmarven, som omfatter et HMGBl-fragmentpeptid valgt fra gruppen, der består af: a) et fragmentpeptid, der omfatter mindst fragmentpeptidet ifølge SEQ ID NO: 3, hvor den øvre grænse er fragmentpeptidet, der består af peptidet ifølge SEQ ID NO: 4; b) et fragmentpeptid, der omfatter mindst fragmentpeptidet ifølge SEQ ID NO: 4, hvor den øvre grænse er fragmentpeptidet, der består af peptidet ifølge SEQ ID NO: 5; og c) et fragmentpeptid, der omfatter mindst fragmentpeptidet ifølge SEQ ID NO: 3, hvor den øvre grænse er fragmentpeptidet, der består af peptidet ifølge SEQ ID NO: 5.
2. Farmaceutisk sammensætning til anvendelse ifølge krav 1, hvor HMGBl-fragmentpeptidet er et peptid, der består af aminosyresekvensen valgt fra gruppen, der består af SEQ ID NO:
3, SEQ ID NO: 4 og SEQ ID NO: 5.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012235786 | 2012-10-25 | ||
| PCT/JP2013/078759 WO2014065348A1 (ja) | 2012-10-25 | 2013-10-24 | Hmgb1断片を利用した脊髄の損傷に対する新規治療法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2913059T3 true DK2913059T3 (da) | 2018-06-25 |
Family
ID=50544721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13849823.3T DK2913059T3 (da) | 2012-10-25 | 2013-10-24 | Hidtil ukendt fremgangsmåde til behandling af rygmarvsskade ved anvendelse af hmgb1-fragment |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9688733B2 (da) |
| EP (1) | EP2913059B1 (da) |
| JP (1) | JP6253590B2 (da) |
| KR (1) | KR102146822B1 (da) |
| CN (1) | CN104955470B (da) |
| AU (1) | AU2013335685B2 (da) |
| BR (1) | BR112015008745B1 (da) |
| CA (1) | CA2889299C (da) |
| DK (1) | DK2913059T3 (da) |
| ES (1) | ES2673861T3 (da) |
| HK (2) | HK1212888A1 (da) |
| MX (1) | MX365899B (da) |
| PL (1) | PL2913059T3 (da) |
| RU (1) | RU2649069C2 (da) |
| SG (1) | SG11201503215XA (da) |
| TR (1) | TR201807769T4 (da) |
| WO (1) | WO2014065348A1 (da) |
| ZA (1) | ZA201502829B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0911513A2 (pt) | 2008-04-30 | 2016-07-12 | Genomix Co Ltd | métodos e agentes para coleta de células tronco da medula óssea funcionais in vivo com alta eficiência |
| CN114106139A (zh) | 2011-04-26 | 2022-03-01 | 斯特姆里姆有限公司 | 用于诱导组织再生的肽及其应用 |
| PL2913058T3 (pl) | 2012-10-25 | 2018-04-30 | Genomix Co., Ltd. | Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1 |
| MX2019008949A (es) | 2017-01-27 | 2019-10-07 | Stemrim Inc | Agente terapeutico para cardiomiopatia, infarto al miocardio antiguo e insuficiencia cardiaca cronica. |
| US11298403B2 (en) | 2017-12-01 | 2022-04-12 | StemRIM Inc. | Therapeutic agent for inflammatory bowel disease |
| WO2019156137A1 (ja) | 2018-02-08 | 2019-08-15 | 株式会社ステムリム | 乾癬の治療薬 |
| EP3862017A4 (en) * | 2018-10-05 | 2022-08-03 | Stemrim Inc. | PEPTIDE WITH MESENCHYMAL STEM CELL MOBILIZATION ACTIVITY |
| JP7448126B2 (ja) * | 2018-10-25 | 2024-03-12 | 国立大学法人大阪大学 | 軟骨疾患の治療薬 |
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| JP3018313B2 (ja) | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
| US20040031072A1 (en) | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
| WO2001008683A1 (en) | 1999-07-28 | 2001-02-08 | The Board Of Trustees Of The Leland Stanford Junior University | Nicotine receptor agonists in stem cell and progenitor cell recruitment |
| EP1114862A3 (de) | 1999-11-17 | 2003-08-06 | Switch Biotech Aktiengesellschaft | Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen |
| JP2004500095A (ja) | 2000-02-24 | 2004-01-08 | エクサイト セラピーズ， インコーポレイテッド | 細胞の同時の刺激および濃縮 |
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| US7754217B2 (en) | 2001-03-16 | 2010-07-13 | Bio3 Research Srl | HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases |
| WO2002088181A2 (en) | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances |
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| CN114106139A (zh) | 2011-04-26 | 2022-03-01 | 斯特姆里姆有限公司 | 用于诱导组织再生的肽及其应用 |
| CN102443064A (zh) | 2011-11-03 | 2012-05-09 | 刘誉 | 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用 |
| PL2913058T3 (pl) | 2012-10-25 | 2018-04-30 | Genomix Co., Ltd. | Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1 |
-
2013
- 2013-10-24 SG SG11201503215XA patent/SG11201503215XA/en unknown
- 2013-10-24 MX MX2015005253A patent/MX365899B/es active IP Right Grant
- 2013-10-24 KR KR1020157013591A patent/KR102146822B1/ko active IP Right Grant
- 2013-10-24 DK DK13849823.3T patent/DK2913059T3/da active
- 2013-10-24 ES ES13849823.3T patent/ES2673861T3/es active Active
- 2013-10-24 EP EP13849823.3A patent/EP2913059B1/en active Active
- 2013-10-24 US US14/436,920 patent/US9688733B2/en active Active
- 2013-10-24 CA CA2889299A patent/CA2889299C/en active Active
- 2013-10-24 RU RU2015119523A patent/RU2649069C2/ru active
- 2013-10-24 AU AU2013335685A patent/AU2013335685B2/en active Active
- 2013-10-24 PL PL13849823T patent/PL2913059T3/pl unknown
- 2013-10-24 JP JP2014543335A patent/JP6253590B2/ja active Active
- 2013-10-24 CN CN201380067951.4A patent/CN104955470B/zh active Active
- 2013-10-24 TR TR2018/07769T patent/TR201807769T4/tr unknown
- 2013-10-24 BR BR112015008745-0A patent/BR112015008745B1/pt active IP Right Grant
- 2013-10-24 WO PCT/JP2013/078759 patent/WO2014065348A1/ja active Application Filing
-
2015
- 2015-04-24 ZA ZA2015/02829A patent/ZA201502829B/en unknown
-
2016
- 2016-01-25 HK HK16100783.3A patent/HK1212888A1/zh unknown
- 2016-02-04 HK HK16101298.9A patent/HK1213201A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL2913059T3 (pl) | 2018-09-28 |
| RU2015119523A (ru) | 2016-12-20 |
| KR20150102957A (ko) | 2015-09-09 |
| HK1212888A1 (zh) | 2016-06-24 |
| WO2014065348A1 (ja) | 2014-05-01 |
| BR112015008745B1 (pt) | 2022-08-02 |
| JPWO2014065348A1 (ja) | 2016-09-08 |
| TR201807769T4 (tr) | 2018-06-21 |
| CA2889299A1 (en) | 2014-05-01 |
| EP2913059A1 (en) | 2015-09-02 |
| BR112015008745A2 (pt) | 2017-11-21 |
| US9688733B2 (en) | 2017-06-27 |
| CA2889299C (en) | 2023-02-14 |
| MX2015005253A (es) | 2015-10-29 |
| AU2013335685A1 (en) | 2015-05-14 |
| SG11201503215XA (en) | 2015-06-29 |
| MX365899B (es) | 2019-06-19 |
| HK1213201A1 (zh) | 2016-06-30 |
| AU2013335685B2 (en) | 2017-10-12 |
| CN104955470B (zh) | 2017-06-16 |
| ES2673861T3 (es) | 2018-06-26 |
| US20150274792A1 (en) | 2015-10-01 |
| KR102146822B1 (ko) | 2020-08-21 |
| JP6253590B2 (ja) | 2017-12-27 |
| CN104955470A (zh) | 2015-09-30 |
| EP2913059B1 (en) | 2018-04-11 |
| ZA201502829B (en) | 2020-11-25 |
| EP2913059A4 (en) | 2016-03-30 |
| RU2649069C2 (ru) | 2018-04-02 |
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