SG11201503215XA - Novel method for treating spinal cord injury using hmgb1 fragment - Google Patents
Novel method for treating spinal cord injury using hmgb1 fragmentInfo
- Publication number
- SG11201503215XA SG11201503215XA SG11201503215XA SG11201503215XA SG11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA SG 11201503215X A SG11201503215X A SG 11201503215XA
- Authority
- SG
- Singapore
- Prior art keywords
- spinal cord
- novel method
- cord injury
- treating spinal
- hmgb1 fragment
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title 1
- 208000020431 spinal cord injury Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012235786 | 2012-10-25 | ||
| PCT/JP2013/078759 WO2014065348A1 (en) | 2012-10-25 | 2013-10-24 | Novel method for treating spinal cord injury using hmgb1 fragment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201503215XA true SG11201503215XA (en) | 2015-06-29 |
Family
ID=50544721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201503215XA SG11201503215XA (en) | 2012-10-25 | 2013-10-24 | Novel method for treating spinal cord injury using hmgb1 fragment |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9688733B2 (en) |
| EP (1) | EP2913059B1 (en) |
| JP (1) | JP6253590B2 (en) |
| KR (1) | KR102146822B1 (en) |
| CN (1) | CN104955470B (en) |
| AU (1) | AU2013335685B2 (en) |
| BR (1) | BR112015008745B1 (en) |
| CA (1) | CA2889299C (en) |
| DK (1) | DK2913059T3 (en) |
| ES (1) | ES2673861T3 (en) |
| HK (2) | HK1212888A1 (en) |
| MX (1) | MX365899B (en) |
| PL (1) | PL2913059T3 (en) |
| RU (1) | RU2649069C2 (en) |
| SG (1) | SG11201503215XA (en) |
| TR (1) | TR201807769T4 (en) |
| WO (1) | WO2014065348A1 (en) |
| ZA (1) | ZA201502829B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102083962B (en) | 2008-04-30 | 2013-03-27 | 吉诺米克斯股份有限公司 | Method for collecting functional cells in vivo with high efficiency |
| PT3358011T (en) | 2011-04-26 | 2020-04-23 | Univ Osaka | Peptide for inducing regeneration of tissue and use thereof |
| MX361259B (en) | 2012-10-25 | 2018-11-30 | Univ Osaka | Novel method for treating cardiac infarction using hmgb1 fragment. |
| AU2018213671B2 (en) | 2017-01-27 | 2024-06-06 | Osaka University | Therapeutic agent for cardiomyopathy, old myocardial infarction and chronic heart failure |
| EP3718561A4 (en) * | 2017-12-01 | 2021-07-21 | Stemrim Inc. | Therapeutic agent for inflammatory bowel disease |
| WO2019156137A1 (en) | 2018-02-08 | 2019-08-15 | 株式会社ステムリム | Therapeutic agent for psoriasis |
| CN113194978B (en) * | 2018-10-05 | 2024-03-08 | 斯特姆里姆有限公司 | Peptides with mobilizing activity of mesenchymal stem cells |
| CA3117107A1 (en) | 2018-10-25 | 2020-04-30 | Osaka University | Therapeutic agent for cartilage disorder |
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| US5658894A (en) | 1989-04-23 | 1997-08-19 | The Trustees Of The University Of Pennsylvania | Compositions for inhibiting restenosis |
| US5661127A (en) | 1995-05-01 | 1997-08-26 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
| JP3018313B2 (en) | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | Bone formation promotion and bone resorption inhibitor |
| US20040031072A1 (en) | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
| BR0012787A (en) | 1999-07-28 | 2002-07-30 | Univ Leland Stanford Junior | Nicotine receptor agonists in stem cell and progenitor cell recruitment |
| EP1114862A3 (en) | 1999-11-17 | 2003-08-06 | Switch Biotech Aktiengesellschaft | Use of polyeptides or their encoding nucleic acids for the diagnosis or treatment of skin diseases and their use in indentifying pharmacologically acitve substances |
| WO2001062895A2 (en) | 2000-02-24 | 2001-08-30 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| JP3421741B2 (en) | 2000-05-18 | 2003-06-30 | 筑波大学長 | Artificial bone marrow, blood cell proliferation method |
| US20040191246A1 (en) | 2003-02-26 | 2004-09-30 | Connelly Patrick R. | Process for in vivo treatment of specific biological targets in bodily fluid |
| ITMI20010562A1 (en) | 2001-03-16 | 2002-09-16 | Marco E Bianchi | HMG1 PROTEIN INHIBITORS OR ANTAGONISTS FOR THE TREATMENT OF VASCULAR DISORDERS |
| DE10121254A1 (en) | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | Functional assay on the activity of human MRP8/MRP14 heterodimer, for diagnosing and treating skin diseases, wounds or wound-healing disturbances with reduced quantity of the heterodimer, in particular a diabetic ulcer |
| AU2002304710A1 (en) | 2001-04-30 | 2002-11-11 | Switch Biotech Ag | Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances |
| KR20040018370A (en) | 2001-05-15 | 2004-03-03 | 노쓰 쇼어-롱 아일랜드 제위시 리서치 인스티튜트 | Use of hmg fragment as anti-inflammatory agents |
| US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| US7304034B2 (en) * | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
| ITMI20011986A1 (en) | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | METHOD AND COMPOSITION FOR THE ACTIVATION OF CELLS PRESENTING THE ANTIGEN |
| EP1459759A4 (en) | 2001-11-19 | 2007-08-29 | Kyowa Hakko Kogyo Kk | Drug mobilizing pluripotent stem cells from tissue into peripheral blood |
| KR100930139B1 (en) | 2001-12-07 | 2009-12-07 | 사이토리 테라퓨틱스, 인크. | Systems and Methods for treating Patients with Processed Lipoaspirate Cells |
| KR20050054907A (en) | 2002-07-03 | 2005-06-10 | 폰다지오네 센트로 산 라파엘 델 몬테 테이보 | Use of hmgb1 in the treatment of tissue damage and/or to promote tissue repair |
| ATE427758T1 (en) | 2002-07-05 | 2009-04-15 | Univ Laval | INHIBITOR OF CHEMOTACTIC FACTOR TO INHIBIT INFLAMMABLE REACTIONS |
| GB0226251D0 (en) | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
| CA2506328A1 (en) | 2002-11-20 | 2004-06-03 | Critical Therapeutics, Inc. | Use of hmgb fragments as anti-inflammatory agents |
| CA2512512A1 (en) | 2003-01-03 | 2004-07-22 | Alcedo Biotech Gmbh | Uses of hmgb, hmgn, hmga proteins |
| WO2004084928A1 (en) | 2003-03-28 | 2004-10-07 | UNIVERSITé LAVAL | S100 protein as neutrophil activator for alleviating neutropenia in cancer treatment |
| US20050014255A1 (en) | 2003-05-29 | 2005-01-20 | Board Of Regents, The University Of Texas System | Stem cells for clinical and commercial uses |
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| ITRM20040058A1 (en) | 2004-02-03 | 2004-05-03 | Marco E Bianchi | HMGB1 INHIBITORS AND ANTAGONISTS ABLE TO REGULATE THE PROLIFERATION OF SMOOTH AND ENDOTELIAL MUSCLE CELLS. |
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| HUE035043T2 (en) | 2006-10-30 | 2018-05-02 | Genomix Co Ltd | Pharmaceutical for promoting functional regeneration of damaged tissue |
| CN102076351A (en) * | 2008-04-30 | 2011-05-25 | 吉诺米克斯股份有限公司 | Pharmaceutical agent for promoting functional regeneration of damaged tissue |
| RU2519714C2 (en) | 2008-04-30 | 2014-06-20 | Дженомикс Ко., Лтд. | Preparation for involving originating from bone marrow pluripotent stem cell into peripheral blood flow |
| CN102083962B (en) | 2008-04-30 | 2013-03-27 | 吉诺米克斯股份有限公司 | Method for collecting functional cells in vivo with high efficiency |
| JP2013508013A (en) * | 2009-10-16 | 2013-03-07 | ザ ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー | Method of treating chronic neural tissue injury using cell therapy strategy |
| EP2494977B1 (en) | 2009-10-28 | 2018-06-13 | Genomix Co., Ltd. | Tissue-regeneration promoter using recruitment of bone marrow mesenchymal stem cells and/or pluripotent stem cells in blood |
| PT3358011T (en) | 2011-04-26 | 2020-04-23 | Univ Osaka | Peptide for inducing regeneration of tissue and use thereof |
| CN102443064A (en) | 2011-11-03 | 2012-05-09 | 刘誉 | Thrombin activity based chimeric peptide with double targeting effects and application thereof |
| MX361259B (en) | 2012-10-25 | 2018-11-30 | Univ Osaka | Novel method for treating cardiac infarction using hmgb1 fragment. |
-
2013
- 2013-10-24 PL PL13849823T patent/PL2913059T3/en unknown
- 2013-10-24 DK DK13849823.3T patent/DK2913059T3/en active
- 2013-10-24 MX MX2015005253A patent/MX365899B/en active IP Right Grant
- 2013-10-24 SG SG11201503215XA patent/SG11201503215XA/en unknown
- 2013-10-24 EP EP13849823.3A patent/EP2913059B1/en active Active
- 2013-10-24 KR KR1020157013591A patent/KR102146822B1/en active IP Right Grant
- 2013-10-24 WO PCT/JP2013/078759 patent/WO2014065348A1/en active Application Filing
- 2013-10-24 US US14/436,920 patent/US9688733B2/en active Active
- 2013-10-24 RU RU2015119523A patent/RU2649069C2/en active
- 2013-10-24 AU AU2013335685A patent/AU2013335685B2/en active Active
- 2013-10-24 TR TR2018/07769T patent/TR201807769T4/en unknown
- 2013-10-24 CN CN201380067951.4A patent/CN104955470B/en active Active
- 2013-10-24 CA CA2889299A patent/CA2889299C/en active Active
- 2013-10-24 BR BR112015008745-0A patent/BR112015008745B1/en active IP Right Grant
- 2013-10-24 ES ES13849823.3T patent/ES2673861T3/en active Active
- 2013-10-24 JP JP2014543335A patent/JP6253590B2/en active Active
-
2015
- 2015-04-24 ZA ZA2015/02829A patent/ZA201502829B/en unknown
-
2016
- 2016-01-25 HK HK16100783.3A patent/HK1212888A1/en unknown
- 2016-02-04 HK HK16101298.9A patent/HK1213201A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2889299C (en) | 2023-02-14 |
| CN104955470B (en) | 2017-06-16 |
| MX2015005253A (en) | 2015-10-29 |
| EP2913059B1 (en) | 2018-04-11 |
| WO2014065348A1 (en) | 2014-05-01 |
| EP2913059A1 (en) | 2015-09-02 |
| JPWO2014065348A1 (en) | 2016-09-08 |
| AU2013335685B2 (en) | 2017-10-12 |
| JP6253590B2 (en) | 2017-12-27 |
| US20150274792A1 (en) | 2015-10-01 |
| KR20150102957A (en) | 2015-09-09 |
| ES2673861T3 (en) | 2018-06-26 |
| CN104955470A (en) | 2015-09-30 |
| AU2013335685A1 (en) | 2015-05-14 |
| US9688733B2 (en) | 2017-06-27 |
| BR112015008745A2 (en) | 2017-11-21 |
| CA2889299A1 (en) | 2014-05-01 |
| DK2913059T3 (en) | 2018-06-25 |
| RU2015119523A (en) | 2016-12-20 |
| MX365899B (en) | 2019-06-19 |
| TR201807769T4 (en) | 2018-06-21 |
| ZA201502829B (en) | 2020-11-25 |
| HK1213201A1 (en) | 2016-06-30 |
| EP2913059A4 (en) | 2016-03-30 |
| BR112015008745B1 (en) | 2022-08-02 |
| KR102146822B1 (en) | 2020-08-21 |
| RU2649069C2 (en) | 2018-04-02 |
| PL2913059T3 (en) | 2018-09-28 |
| HK1212888A1 (en) | 2016-06-24 |
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