DK2890432T3 - Fremføringsdrivmekanismer med kontrolleret variabel hastighed til lægemiddelfremføringspumper - Google Patents

Fremføringsdrivmekanismer med kontrolleret variabel hastighed til lægemiddelfremføringspumper Download PDF

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Publication number
DK2890432T3
DK2890432T3 DK13762339.3T DK13762339T DK2890432T3 DK 2890432 T3 DK2890432 T3 DK 2890432T3 DK 13762339 T DK13762339 T DK 13762339T DK 2890432 T3 DK2890432 T3 DK 2890432T3
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Denmark
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gear
drug
drive mechanism
drive
piston
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DK13762339.3T
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English (en)
Inventor
Iv Paul F Bente
Ian B Hanson
Vincent E Mandes
Sean M O'connor
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Unitract Syringe Pty Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546—Front-loading type injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14208—Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate

Claims (15)

1. Fremføringsdrivmekasnime med kontrolleret variabel hastighed (100), som omfatter: et drivmekanismehus (130), som indledningsvis mindst delvist huser en påvirkningsdel (122), der er placeret i en indledningsvis aktiveret tilstand i et indvendigt hulrum i et stempel (110); et tandhjulsdrev (120) med et tandhjul (520) og en i det væsentlige aksial indvendig gennemføring (120A); der er kendetegnet ved, at den yderligere omfatter: en første skrue (124), der er mindst delvist placeret inde i den aksiale indvendige gennemføring (120A), hvilken første skrue (124) også har en i det væsentlige aksial gennemføring (124A) og en udvendig første stigning (124B), hvor den udvendige første stigning (124B) er konfigureret til at gå i indgreb med en første møtrik (126), der også er placeret inde i den indvendig gennemføring (120A) på tandhjulsdrevet (120); en anden møtrik (128), der er konfigureret til at gå i indgreb med en anden skrue (132) med en udvendig anden stigning (132B), hvilken anden møtrik (128) er anbragt i en aksial position (HOB) af et stempel (110), hvilken aksiale position (110B) og anden møtrik (128) er anbragt, så de er placeret mindst delvist inde i den aksiale gennemføring (124A) af den første skrue (124); hvor stemplet (110) har en grænsefladeoverflade (HOC) , der støder op til en stempelforsegling (60) og er konfigureret til aksial translation af stempelforseglingen (60) ved hjælp af en kraft, der påføres den fra påvirkningsdelen (122), fra en første position til en anden position i lægemiddelbeholderen (50) til lægemiddelfremføring, og hvor påvirkningsdelen (122) måles fra fri ekspansion fra dens aktiverede tilstand.
2. Drivmekanisme (100) ifølge krav 1, hvor lægemiddelbeholderen (50) indeholder en lægemiddelvæske i et lægemiddelkammer (21).
3. Drivmekanisme (100) ifølge et hvilket som helst af kravene 1 til 2, hvor en dækselmuffe (140) kan være konfigureret til at gå i indgreb med og glide på stemplet (110) mellem stemplet (110) og en distal ende af drivmekanismehuset (130) .
4. Drivmekanisme (100) ifølge et hvilket som helst af kravene 1 til 3, hvor den første møtrik (126) er rotationsfastgjort til tandhjulsdrevet (120).
5. Drivmekanisme (100) ifølge et hvilket som helst af kravene 1 til 4, hvor den anden møtrik (128) er rotationsfastgjort til stemplet (110).
6. Drivmekanisme (100) ifølge et hvilket som helst af kravene 1 til 5, der yderligere omfatter en tandhjulsindretningsmekanisme (500) med en motor (530), hvilken tandhjulsindretningsmekanisme (500) er konfigureret til at gå i indgreb med tandhjul (520) til måling af den fri ekspansion af påvirkningsdelen (122) fra dens aktiverede tilstand.
7. Drivmekanisme (100) ifølge krav 6, hvor tandhjulsindretningsmekanismen (500) har en motor (530), der yderligere omfatter et tandhjulsdrev (530A), der udgår fra motor (530) ; et første sammensat tandhjul (526) med et første tandhjul (526B) og et anden tandhjul (526A); et andet sammensat tandhjul (528) med et første tandhjul (528B) og et anden tandhjul (528A); og et udløsertandhjul (524); hvor tandhjulsdrevet (530A) berører det første tandhjul (526B) af det første sammensatte tandhjul (526), det andet tandhjul (526A) af det første sammensatte tandhjul (526) berører det første tandhjul (528B) af det andet sammensatte tandhjul (528), det andet tandhjul (528A) af det andet sammensatte tandhjul (528) berører udløsertandhjulet (524), og udløsertandhjulet (524) berører tandhjul (520) til viderebringelse af bevægelse til drivmekanismen (100).
8. Drivmekanisme (100) ifølge et hvilket som helst af kravene 1 til 7, hvor målingen af påvirkningsdelen (122) ved hjælp af motoren (530) kontrollerer hastigheden eller profilen af lægemiddelfremføring til en bruger.
9. Drivmekanisme (100) ifølge et hvilket som helst af kravene 1 til 8, hvor en statuslæser (600, 1600) kan være konfigureret til at læse eller genkende en eller flere tilsvarende statusudløsere, hvor interaktion mellem statuslæseren (600, 1600) og statusudløserne under drift af drivmekanismen (100) overfører et signal til et strøm- og kontrolsystem (400) til tilvejebringelse af feedback til en bruger.
10. Drivmekanisme (100) ifølge krav 9, hvor statuslæseren (1600) er en optisk statuslæser og de tilsvarende statusudløsere er tandhjulstænder på udløsertandhjulet (524).
11. Drivmekanisme (100) ifølge krav 9, hvor statuslæseren (600) er en mekanisk statuslæser og de tilsvarende statusudløsere er tandhjulstænder på udløsertandhjulet (524).
12. Drivmekanisme (100) ifølge krav 9, hvor statuslæseren (600) er en mekanisk statuslæser og de tilsvarende statusudløsere er udvendige træk på stemplet (110) og/eller muffen (140) .
13. Drivmekanisme (100) ifølge krav 9, hvor statuslæseren (600) er en optisk statuslæser og de tilsvarende statusudløsere er udvendige træk på stemplet (110) og/eller muffen (140).
14. Drivmekanisme (100) ifølge et hvilket som helst af kravene 1 til 13, hvor funktionen af tandhjulsindretningsmekanismen (500), der har en motor (530), er præprogrammeret eller dynamisk kontrolleret ved hjælp af et strøm- og kontrolsystem (400) til at udføre en ønsket lægemiddelfremføringshastighed eller -profil.
15. Lægemiddelfremføringspumpe (10) med en fremføringsmekanisme med kontrolleret variabel hastighed (100), der omfatter et hus (12) og en indretningsplatform (20), hvorpå er placeret en aktiveringsmekanisme (14), en indføringsmekanisme (200), en væskevejsforbindelse (300), et strøm- og kontrolsystem (400) og fremføringsdrivmekasnimen med kontrolleret variabel hastighed (100) ifølge et hvilket som helst af kravene 1 til 14, der har en lægemiddelbeholder (50).
DK13762339.3T 2012-08-29 2013-08-29 Fremføringsdrivmekanismer med kontrolleret variabel hastighed til lægemiddelfremføringspumper DK2890432T3 (da)

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US201261694534P 2012-08-29 2012-08-29
US201261731744P 2012-11-30 2012-11-30
US201361748667P 2013-01-03 2013-01-03
PCT/US2013/057327 WO2014036285A2 (en) 2012-08-29 2013-08-29 Variable rate controlled delivery drive mechanisms for drug delivery pumps

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DK2890432T3 true DK2890432T3 (da) 2017-09-25

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DK13763364.0T DK2890433T3 (da) 2012-08-29 2013-08-29 Drivmekanisme med kontrolleret administation til lægemiddeladministrationspumper
DK16151332.0T DK3028727T3 (da) 2012-08-29 2013-08-29 Styret leveringsdrivmekanisme til medicinleveringspumpe
DK13762339.3T DK2890432T3 (da) 2012-08-29 2013-08-29 Fremføringsdrivmekanismer med kontrolleret variabel hastighed til lægemiddelfremføringspumper
DK13762335.1T DK2890431T3 (da) 2012-08-29 2013-08-29 Drivmekanismer med styret afgivelse til lægemiddelafgivelsespumper

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DK13763364.0T DK2890433T3 (da) 2012-08-29 2013-08-29 Drivmekanisme med kontrolleret administation til lægemiddeladministrationspumper
DK16151332.0T DK3028727T3 (da) 2012-08-29 2013-08-29 Styret leveringsdrivmekanisme til medicinleveringspumpe

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US (5) US10092693B2 (da)
EP (6) EP2890432B1 (da)
JP (5) JP6645829B2 (da)
KR (3) KR20150048834A (da)
CN (3) CN104602733B (da)
AU (3) AU2013308655B2 (da)
BR (2) BR112015003422A2 (da)
CA (3) CA2881839A1 (da)
DK (4) DK2890433T3 (da)
ES (3) ES2637229T3 (da)
HK (2) HK1211885A1 (da)
IL (3) IL236958B (da)
MX (4) MX352388B (da)
PT (4) PT3028727T (da)
WO (3) WO2014036308A2 (da)

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