DK2539707T3 - Kunstige mycolsyremembraner - Google Patents

Kunstige mycolsyremembraner Download PDF

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Publication number
DK2539707T3
DK2539707T3 DK11748021.0T DK11748021T DK2539707T3 DK 2539707 T3 DK2539707 T3 DK 2539707T3 DK 11748021 T DK11748021 T DK 11748021T DK 2539707 T3 DK2539707 T3 DK 2539707T3
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Denmark
Prior art keywords
mycolic acid
acid membranes
artificial
artificial mycolic
membranes
Prior art date
Application number
DK11748021.0T
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English (en)
Inventor
Jens H Gundlach
Ian M Derrington
Kyle W Langford
Original Assignee
Univ Washington
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Publication of DK2539707T3 publication Critical patent/DK2539707T3/da

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    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • G—PHYSICS
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    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • Y10S977/781—Possessing nonosized surface openings that extend partially into or completely through the host material
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    • Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Human Computer Interaction (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
DK11748021.0T 2010-02-23 2011-02-23 Kunstige mycolsyremembraner DK2539707T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30744110P 2010-02-23 2010-02-23
US37570710P 2010-08-20 2010-08-20
PCT/US2011/025960 WO2011106456A2 (en) 2010-02-23 2011-02-23 Artificial mycolic acid membranes

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Publication Number Publication Date
DK2539707T3 true DK2539707T3 (da) 2021-07-26

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DK11748021.0T DK2539707T3 (da) 2010-02-23 2011-02-23 Kunstige mycolsyremembraner
DK11748022.8T DK2539465T3 (da) 2010-02-23 2011-02-23 Analytsekventering med nanoporer

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DK11748022.8T DK2539465T3 (da) 2010-02-23 2011-02-23 Analytsekventering med nanoporer

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US (5) US8999716B2 (da)
EP (4) EP3933402A1 (da)
CN (2) CN102834716B (da)
CA (5) CA3116307C (da)
DK (2) DK2539707T3 (da)
ES (2) ES2978883T3 (da)
FI (1) FI2539465T3 (da)
WO (2) WO2011106459A2 (da)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007146158A1 (en) 2006-06-07 2007-12-21 The Trustees Of Columbia University In The City Of New York Dna sequencing by nanopore using modified nucleotides
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
US9678055B2 (en) 2010-02-08 2017-06-13 Genia Technologies, Inc. Methods for forming a nanopore in a lipid bilayer
US9605307B2 (en) 2010-02-08 2017-03-28 Genia Technologies, Inc. Systems and methods for forming a nanopore in a lipid bilayer
EP3933402A1 (en) 2010-02-23 2022-01-05 University of Washington Method of making unsupported artificial mycolic acid membranes
ES2641871T3 (es) 2010-12-17 2017-11-14 The Trustees Of Columbia University In The City Of New York Secuenciación de ADN mediante síntesis usando nucleótidos modificados y detección con nanoporos
GB2500360B (en) 2010-12-22 2019-10-23 Genia Tech Inc Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
US9581563B2 (en) 2011-01-24 2017-02-28 Genia Technologies, Inc. System for communicating information from an array of sensors
US9110478B2 (en) 2011-01-27 2015-08-18 Genia Technologies, Inc. Temperature regulation of measurement arrays
SG10201604316WA (en) 2011-05-27 2016-07-28 Oxford Nanopore Tech Ltd Coupling method
EP2807476A4 (en) 2012-01-20 2015-12-09 Genia Technologies Inc MOLECULAR DETECTION AND SEQUENCING USING NANOPORES
US8541849B2 (en) * 2012-02-14 2013-09-24 Genia Technologies, Inc. Noise shielding techniques for ultra low current measurements in biochemical applications
JP6226888B2 (ja) 2012-02-16 2017-11-08 オックスフォード ナノポール テクノロジーズ リミテッド ポリマーの測定の解析
US8986629B2 (en) 2012-02-27 2015-03-24 Genia Technologies, Inc. Sensor circuit for controlling, detecting, and measuring a molecular complex
CA2869753A1 (en) 2012-04-09 2013-10-17 Jingyue Ju Method of preparation of nanopore and uses thereof
JP6271505B2 (ja) 2012-04-10 2018-01-31 オックスフォード ナノポール テクノロジーズ リミテッド 変異体ライセニンポア
US10612083B2 (en) 2012-04-19 2020-04-07 University Of Washington Through Its Center For Commercialization Methods and compositions for generating reference maps for nanopore-based polymer analysis
CN104350162A (zh) 2012-06-15 2015-02-11 吉尼亚科技公司 芯片设置和高精确度核酸测序
ES2967793T3 (es) * 2012-08-03 2024-05-03 Univ Washington Through Its Center For Commercialization Composiciones y procedimientos para mejorar la secuenciación de nanoporos
CN102867851B (zh) * 2012-09-07 2015-10-28 中国科学院苏州纳米技术与纳米仿生研究所 离子束流信号放大器及其制造方法
WO2014071250A1 (en) * 2012-11-01 2014-05-08 University Of Washington Through Its Center For Commercialization Methods for detecting and mapping modifications to nucleic acid polymers using nanopore systems
US9605309B2 (en) 2012-11-09 2017-03-28 Genia Technologies, Inc. Nucleic acid sequencing using tags
GB201222928D0 (en) 2012-12-19 2013-01-30 Oxford Nanopore Tech Ltd Analysis of a polynucleotide
US9759711B2 (en) 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
KR20150119353A (ko) * 2013-02-20 2015-10-23 이브 바이오메디컬, 인크. 나노구조-기반 핵산 서열분석을 위한 방법 및 조성물
WO2014144883A1 (en) 2013-03-15 2014-09-18 The Trustees Of Columbia University In The City Of New York Raman cluster tagged molecules for biological imaging
CN105102627B (zh) 2013-03-15 2018-10-19 纽约哥伦比亚大学理事会 用于检测样品中多种预定化合物的方法
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
US10017814B2 (en) 2013-08-30 2018-07-10 University Of Washington Through Its Center For Commercialization Selective modification of polymer subunits to improve nanopore-based analysis
WO2015051378A1 (en) * 2013-10-04 2015-04-09 University Of Washington Through Its Center For Commercialization Systems and methods for nanopore-based analysis of nucleic acids
US9551697B2 (en) 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
US9322062B2 (en) 2013-10-23 2016-04-26 Genia Technologies, Inc. Process for biosensor well formation
EP3640349A3 (en) 2013-10-23 2020-07-29 Roche Sequencing Solutions, Inc. High speed molecular sensing with nanopores
CN111534504B (zh) 2014-01-22 2024-06-21 牛津纳米孔科技公开有限公司 将一个或多个多核苷酸结合蛋白连接到靶多核苷酸的方法
GB201406155D0 (en) 2014-04-04 2014-05-21 Oxford Nanopore Tech Ltd Method
CN106133513B (zh) * 2014-02-19 2019-08-13 华盛顿大学 蛋白质特征的基于纳米孔的分析
US10047392B2 (en) 2014-02-21 2018-08-14 Northeastern University Fluorescence-based analysis of biopolymers using nanopores
US20170022546A1 (en) * 2014-03-10 2017-01-26 Rashid Bashir Detection and quantification of methylation in dna
WO2015148402A1 (en) 2014-03-24 2015-10-01 The Trustees Of Columbia Univeristy In The City Of New York Chemical methods for producing tagged nucleotides
US10337060B2 (en) 2014-04-04 2019-07-02 Oxford Nanopore Technologies Ltd. Method for characterising a double stranded nucleic acid using a nano-pore and anchor molecules at both ends of said nucleic acid
ES2895625T3 (es) 2014-04-16 2022-02-22 Uab Res Found Nanoporos de MSP y usos de los mismos
CN106459159B (zh) 2014-05-02 2021-11-30 牛津纳米孔技术公司 突变孔
WO2015187670A2 (en) 2014-06-03 2015-12-10 Illumina, Inc. Compositions, systems, and methods for detecting events using tethers anchored to or adjacent to nanopores
US10519499B2 (en) 2014-07-31 2019-12-31 Illumina, Inc. Hybrid nanopore sensors
CN114605507A (zh) 2014-09-01 2022-06-10 弗拉芒区生物技术研究所 突变csgg孔
US10266885B2 (en) 2014-10-07 2019-04-23 Oxford Nanopore Technologies Ltd. Mutant pores
KR102551897B1 (ko) 2014-10-16 2023-07-06 옥스포드 나노포어 테크놀로지즈 피엘씨 폴리머의 분석
GB201418469D0 (en) 2014-10-17 2014-12-03 Oxford Nanopore Tech Ltd Method
AU2015335616B2 (en) * 2014-10-24 2019-09-12 Quantapore, Inc. Efficient optical analysis of polymers using arrays of nanostructures
GB201502810D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Method
GB201502809D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Mutant pore
CN107735686B (zh) 2015-04-14 2021-06-11 鲁汶天主教大学 具有内部蛋白质衔接子的纳米孔
IL255758B (en) 2015-06-03 2022-07-01 Illumina Inc Compositions, systems and methods for sequencing polynucleotides using tethers anchored to polymerases attached to nanopores
CA3011830A1 (en) 2015-12-08 2017-06-15 Katholieke Universiteit Leuven Ku Leuven Research & Development Modified nanopores, compositions comprising the same, and uses thereof
CN105779279A (zh) * 2016-02-29 2016-07-20 东南大学 一种基于二维层状材料的纳米孔传感器件及其构建方法
WO2017149317A1 (en) 2016-03-02 2017-09-08 Oxford Nanopore Technologies Limited Mutant pore
CN118256605A (zh) 2016-04-06 2024-06-28 牛津纳米孔科技公开有限公司 突变体孔
US11124827B2 (en) * 2016-06-23 2021-09-21 Roche Sequencing Solutions, Inc. Period-to-period analysis of AC signals from nanopore sequencing
GB201707122D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Pore
JP6929375B2 (ja) * 2017-05-12 2021-09-01 ユニバーサル シークエンシング テクノロジー コーポレーション ディービーエー ユーエスティー コーポレーション 軟磁性構造を用いたナノ細孔を介してｄｎａ、ｒｎａおよび他の生体分子を引っ張る方法およびシステム
SG11201913174PA (en) 2017-06-30 2020-01-30 Vib Vzw Novel protein pores
EP3732484B1 (en) 2017-12-28 2023-06-07 F. Hoffmann-La Roche AG Measuring and removing noise in stochastic signals from a nanopore dna sequencing system driven by an alternating signal
GB2589159B (en) 2017-12-29 2023-04-05 Clear Labs Inc Nucleic acid sequencing apparatus
AU2019222673B2 (en) * 2018-02-16 2022-01-20 Illumina, Inc. Device for sequencing
WO2019226822A1 (en) * 2018-05-23 2019-11-28 The Regents Of The University Of California Methods of analyzing capped ribonucleic acids
GB201811623D0 (en) * 2018-07-16 2018-08-29 Univ Oxford Innovation Ltd Molecular hopper
US20220366313A1 (en) * 2019-02-14 2022-11-17 University Of Washington Systems and methods for improved nanopore-based analysis of nucleic acids
CN112831395B (zh) * 2019-11-25 2024-01-16 深圳华大生命科学研究院 用于纳米孔测序的类细胞膜
CN111424075B (zh) * 2020-04-10 2021-01-15 西咸新区予果微码生物科技有限公司 一种基于第三代测序技术的微生物检测方法及系统
US20240150824A1 (en) 2020-08-11 2024-05-09 Roche Sequencing Solutions, Inc. Nucleoside-5'-oligophosphates tagged with postiviely-charged polymers, nanopores incorporating negative charges, and methods and systems using the same
WO2022237883A1 (en) * 2021-05-13 2022-11-17 Nanjing University Structural-profiling of analytes by nanopore trapping
JP2024526114A (ja) 2021-06-17 2024-07-17 エフ． ホフマン－ラ ロシュ アーゲー チャネルをねじ込みで通る負に荷電したポリマーを有する操作されたナノポア
CN114199875B (zh) * 2022-02-18 2022-05-20 之江实验室 一种蛋白质多聚体是否可作为力缓冲剂的判断方法及装置

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307229A (en) 1979-11-07 1981-12-22 Avraham Liav 6,6'-Diesters of trehalose and process for the synthesis thereof
US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
DE3248167A1 (de) 1982-12-27 1984-06-28 Wintershall Ag, 3100 Celle Trehaloselipidtetraester
EP0261248B1 (en) 1986-03-20 1991-05-29 Sawai Pharmaceutical Co., Ltd. $g(a), $g(a)-TREHALOSE TRIMYCOLATE AND MEDICINAL COMPOSITION
US5049664A (en) 1988-08-26 1991-09-17 Sawai Pharmaceutical Co., Ltd. Trehalose derivatives
JPH07248329A (ja) * 1994-03-11 1995-09-26 Nippon Bio Ratsudo Lab Kk 結核感染症検査用膜およびこれを用いる結核感染症関連抗体の検出方法
US5658749A (en) * 1994-04-05 1997-08-19 Corning Clinical Laboratories, Inc. Method for processing mycobacteria
JPH11500906A (ja) 1995-02-22 1999-01-26 アドコック、イングラム、リミテッド 脂質細胞壁成分の単離および精製法
US5795782A (en) 1995-03-17 1998-08-18 President & Fellows Of Harvard College Characterization of individual polymer molecules based on monomer-interface interactions
US6362002B1 (en) 1995-03-17 2002-03-26 President And Fellows Of Harvard College Characterization of individual polymer molecules based on monomer-interface interactions
EP0971733A1 (en) * 1997-03-03 2000-01-19 Adcock Ingram Limited A composition comprising a carrier and a purified mycobacterial lipid cell-wall component and its use in the prevention, treatment and diagnosis of disease
US6406880B1 (en) * 1997-05-02 2002-06-18 Integrated Research Technology, Llc Betaines as adjuvants to susceptibility testing and antimicrobial therapy
US6267872B1 (en) 1998-11-06 2001-07-31 The Regents Of The University Of California Miniature support for thin films containing single channels or nanopores and methods for using same
WO2000039333A1 (en) 1998-12-23 2000-07-06 Jones Elizabeth Louise Sequencing method using magnifying tags
NO986133D0 (no) 1998-12-23 1998-12-23 Preben Lexow FremgangsmÕte for DNA-sekvensering
ATE316582T1 (de) 1999-09-07 2006-02-15 Univ California Verfahren um die anwesenheit von doppelsträngiger dns in einer probe nachzuweisen
WO2002009647A2 (en) * 2000-07-28 2002-02-07 Emory University Biological component comprising artificial membrane
AU2002239284A1 (en) * 2000-11-27 2002-06-03 The Regents Of The University Of California Methods and devices for characterizing duplex nucleic acid molecules
US6833249B2 (en) * 2002-03-22 2004-12-21 Council Of Scientific And Industrial Research Quick and sensitive method of quantifying mycolic acid to develop anti-microbial agents and a diagnostic kit thereof
ITMI20022096A1 (it) 2002-10-03 2004-04-04 Garden Ventures S R L Sistema di registrazione di un programma tv impostabile
AU2004210964A1 (en) 2003-02-11 2004-08-26 University Of Washington Stimuli-responsive polymer conjugates and related methods
US7444053B2 (en) 2003-06-16 2008-10-28 The Regents Of The University Of California Integrated electrical and optical sensor for biomolecule analysis with single molecule sensitivity
US7594359B2 (en) 2004-03-12 2009-09-29 Gm Global Technology Operations, Inc. Active seal assemblies for sound isolation
WO2006028508A2 (en) 2004-03-23 2006-03-16 President And Fellows Of Harvard College Methods and apparatus for characterizing polynucleotides
US20070269843A1 (en) * 2004-04-28 2007-11-22 Integrated Research Technology, Llc. Diagnostic Assays That Use Mycobacteriophages
US7749520B2 (en) * 2004-07-07 2010-07-06 Statens Serum Institut Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids
EP1784754A4 (en) * 2004-08-13 2009-05-27 Harvard College OPTI-NANOPORE DNA READING PLATFORM WITH ULTRAHOLE THROUGHPUT
GB0504184D0 (en) 2005-03-01 2005-04-06 Lingvitae As Method
US8465983B1 (en) 2005-08-19 2013-06-18 Gabriel P. Lopez Detection and delivery systems utilizing supported lipid bilayers
WO2007041621A2 (en) * 2005-10-03 2007-04-12 Xingsheng Sean Ling Hybridization assisted nanopore sequencing
WO2007146158A1 (en) 2006-06-07 2007-12-21 The Trustees Of Columbia University In The City Of New York Dna sequencing by nanopore using modified nucleotides
EP2639578B1 (en) * 2006-12-14 2016-09-14 Life Technologies Corporation Apparatus for measuring analytes using large scale fet arrays
US20110121840A1 (en) 2007-02-20 2011-05-26 Gurdial Singh Sanghera Lipid Bilayer Sensor System
CA2684801C (en) * 2007-04-04 2017-10-10 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
CA2685896C (en) 2007-05-08 2016-10-04 Prionics Ag Method for the diagnosis of tuberculosis by detecting an immune response to ompatb
GB0807305D0 (en) * 2008-04-22 2008-05-28 Univ Ghent Compounds for use in therapy
CA2774710C (en) 2008-09-22 2016-08-02 University Of Washington Msp nanopores and related methods
EP3933402A1 (en) 2010-02-23 2022-01-05 University of Washington Method of making unsupported artificial mycolic acid membranes
US9893808B2 (en) 2016-03-18 2018-02-13 Target Brands, Inc. VLC location data applications in a retail setting

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