DK2379580T3 - Hidtil ukendte antibakterielle midler til behandling af gram-positive infektioner - Google Patents

Hidtil ukendte antibakterielle midler til behandling af gram-positive infektioner

Info

Publication number
DK2379580T3
DK2379580T3 DK09795876.3T DK09795876T DK2379580T3 DK 2379580 T3 DK2379580 T3 DK 2379580T3 DK 09795876 T DK09795876 T DK 09795876T DK 2379580 T3 DK2379580 T3 DK 2379580T3
Authority
DK
Denmark
Prior art keywords
antibacterial agents
treating gram
positive infections
unknown
unknown antibacterial
Prior art date
Application number
DK09795876.3T
Other languages
Danish (da)
English (en)
Inventor
Andre Lee Pearson
Chester A Metcalf Iii
Jing Li
Original Assignee
Cubist Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cubist Pharm Inc filed Critical Cubist Pharm Inc
Application granted granted Critical
Publication of DK2379580T3 publication Critical patent/DK2379580T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK09795876.3T 2008-12-22 2009-12-18 Hidtil ukendte antibakterielle midler til behandling af gram-positive infektioner DK2379580T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13987508P 2008-12-22 2008-12-22
PCT/US2009/068747 WO2010075215A1 (en) 2008-12-22 2009-12-18 Novel antibacterial agents for the treatment of gram positive infections

Publications (1)

Publication Number Publication Date
DK2379580T3 true DK2379580T3 (da) 2014-01-20

Family

ID=41718893

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09795876.3T DK2379580T3 (da) 2008-12-22 2009-12-18 Hidtil ukendte antibakterielle midler til behandling af gram-positive infektioner

Country Status (26)

Country Link
US (3) US8507647B2 (OSRAM)
EP (2) EP2379580B1 (OSRAM)
JP (1) JP5670914B2 (OSRAM)
KR (1) KR101717795B1 (OSRAM)
CN (1) CN102325787B (OSRAM)
AR (1) AR074833A1 (OSRAM)
AU (1) AU2009330245C1 (OSRAM)
BR (1) BRPI0923567A2 (OSRAM)
CA (1) CA2747965C (OSRAM)
CY (1) CY1114883T1 (OSRAM)
DK (1) DK2379580T3 (OSRAM)
ES (1) ES2442167T3 (OSRAM)
HR (1) HRP20131170T1 (OSRAM)
IL (1) IL213638A0 (OSRAM)
MX (1) MX2011006803A (OSRAM)
NZ (1) NZ594019A (OSRAM)
PL (1) PL2379580T3 (OSRAM)
PT (1) PT2379580E (OSRAM)
RS (1) RS53152B (OSRAM)
RU (1) RU2512396C2 (OSRAM)
SG (1) SG172299A1 (OSRAM)
SI (1) SI2379580T1 (OSRAM)
SM (1) SMT201400037B (OSRAM)
TW (1) TWI444198B (OSRAM)
WO (1) WO2010075215A1 (OSRAM)
ZA (1) ZA201104693B (OSRAM)

Families Citing this family (11)

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JP2014515371A (ja) 2011-05-26 2014-06-30 キュービスト ファーマシューティカルズ， インコーポレイテッド Ｃｂ−１８３，３１５組成物および関連する方法
US10377699B2 (en) * 2013-11-06 2019-08-13 The University Of Hong Kong Daptomycin analogues and a method for the preparation of daptomycin or a daptomycin analogue
WO2015172047A1 (en) * 2014-05-08 2015-11-12 Merck Sharp & Dohme Corp. Cyclic peptide compounds and related methods, salts and compositions
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
US11667674B2 (en) * 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
MA44721B1 (fr) * 2016-04-22 2020-05-29 Astrazeneca Ab 151 85 Soedertaelje Inhibiteurs de mcl1 macrocycliques pour le traitement du cancer
US10098890B2 (en) 2016-10-29 2018-10-16 Cipla Limited Stable carfilzomib formulations
IT201600127655A1 (it) * 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
US10072045B1 (en) 2017-06-26 2018-09-11 Ramapo Pharmaceuticals, Inc. Antibacterial lipopeptides and methods for their preparation and use
US10526343B2 (en) 2018-03-26 2020-01-07 University Of Sharjah Heterocyclic systems and pharmaceutical applications thereof
RU2762182C1 (ru) * 2020-12-08 2021-12-16 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Гауземицины А и В - гликолипопептидные антибактериальные антибиотики и способ их получения

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USRE32455E (en) * 1978-10-16 1987-07-07 Eli Lilly And Company A-21978 antibiotics and process for their production
DE3376424D1 (en) * 1982-02-27 1988-06-01 Beecham Group Plc Antibacterial 1-normon-2-yl-heterocyclic compounds
US4524135A (en) * 1982-05-21 1985-06-18 Eli Lilly And Company A-21978C cyclic peptides
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IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production
US4399067A (en) * 1982-05-21 1983-08-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4396543A (en) * 1982-05-21 1983-08-02 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4482487A (en) 1982-05-21 1984-11-13 Eli Lilly And Company A-21978C cyclic peptides
USRE32311E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
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US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
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DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
DE69739532D1 (de) 1996-03-08 2009-09-24 Astellas Pharma Inc Prozess für die deacylierung von zyklischen lipopeptiden.
DE19807972A1 (de) 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
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EP2298790A1 (en) 1999-12-15 2011-03-23 Cubist Pharmaceuticals, Inc. Daptomycin analogs as antibacterial agents
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Also Published As

Publication number Publication date
US20140073558A1 (en) 2014-03-13
KR20110114592A (ko) 2011-10-19
JP2012513467A (ja) 2012-06-14
RS53152B (sr) 2014-06-30
KR101717795B1 (ko) 2017-03-17
TWI444198B (zh) 2014-07-11
JP5670914B2 (ja) 2015-02-18
IL213638A0 (en) 2011-07-31
US20100184649A1 (en) 2010-07-22
CA2747965A1 (en) 2010-07-01
SMT201400037B (it) 2014-05-07
AU2009330245B2 (en) 2013-05-02
TW201028161A (en) 2010-08-01
AU2009330245C1 (en) 2013-09-26
EP2379580A1 (en) 2011-10-26
HRP20131170T1 (hr) 2014-01-03
HK1161886A1 (en) 2012-08-10
RU2512396C2 (ru) 2014-04-10
RU2011130278A (ru) 2013-01-27
BRPI0923567A2 (pt) 2016-09-27
US8507647B2 (en) 2013-08-13
AU2009330245A1 (en) 2011-08-04
CA2747965C (en) 2017-06-27
PT2379580E (pt) 2014-01-20
ZA201104693B (en) 2013-01-30
CN102325787A (zh) 2012-01-18
CN102325787B (zh) 2014-05-28
CY1114883T1 (el) 2016-12-14
EP2379580B1 (en) 2013-10-23
ES2442167T3 (es) 2014-02-10
SG172299A1 (en) 2011-07-28
SI2379580T1 (sl) 2014-02-28
AR074833A1 (es) 2011-02-16
MX2011006803A (es) 2011-09-06
NZ594019A (en) 2013-08-30
PL2379580T3 (pl) 2014-05-30
EP2674437A1 (en) 2013-12-18
WO2010075215A1 (en) 2010-07-01
US20150337013A1 (en) 2015-11-26

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