SI2379580T1 - Nova antibakterijska sredstva za zdravljenje grampozitivnih okuĹľb - Google Patents

Nova antibakterijska sredstva za zdravljenje grampozitivnih okuĹľb

Info

Publication number
SI2379580T1
SI2379580T1 SI200930815T SI200930815T SI2379580T1 SI 2379580 T1 SI2379580 T1 SI 2379580T1 SI 200930815 T SI200930815 T SI 200930815T SI 200930815 T SI200930815 T SI 200930815T SI 2379580 T1 SI2379580 T1 SI 2379580T1
Authority
SI
Slovenia
Prior art keywords
treatment
antibacterial agents
gram positive
novel antibacterial
positive infections
Prior art date
Application number
SI200930815T
Other languages
English (en)
Slovenian (sl)
Inventor
Andre Lee Pearson
Chester A. Metcalf Iii
Jing Li
Original Assignee
Cubist Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cubist Pharmaceuticals, Inc. filed Critical Cubist Pharmaceuticals, Inc.
Publication of SI2379580T1 publication Critical patent/SI2379580T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200930815T 2008-12-22 2009-12-18 Nova antibakterijska sredstva za zdravljenje grampozitivnih okuĹľb SI2379580T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13987508P 2008-12-22 2008-12-22
PCT/US2009/068747 WO2010075215A1 (en) 2008-12-22 2009-12-18 Novel antibacterial agents for the treatment of gram positive infections
EP09795876.3A EP2379580B1 (en) 2008-12-22 2009-12-18 Novel antibacterial agents for the treatment of gram positive infections

Publications (1)

Publication Number Publication Date
SI2379580T1 true SI2379580T1 (sl) 2014-02-28

Family

ID=41718893

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200930815T SI2379580T1 (sl) 2008-12-22 2009-12-18 Nova antibakterijska sredstva za zdravljenje grampozitivnih okuĹľb

Country Status (26)

Country Link
US (3) US8507647B2 (OSRAM)
EP (2) EP2379580B1 (OSRAM)
JP (1) JP5670914B2 (OSRAM)
KR (1) KR101717795B1 (OSRAM)
CN (1) CN102325787B (OSRAM)
AR (1) AR074833A1 (OSRAM)
AU (1) AU2009330245C1 (OSRAM)
BR (1) BRPI0923567A2 (OSRAM)
CA (1) CA2747965C (OSRAM)
CY (1) CY1114883T1 (OSRAM)
DK (1) DK2379580T3 (OSRAM)
ES (1) ES2442167T3 (OSRAM)
HR (1) HRP20131170T1 (OSRAM)
IL (1) IL213638A0 (OSRAM)
MX (1) MX2011006803A (OSRAM)
NZ (1) NZ594019A (OSRAM)
PL (1) PL2379580T3 (OSRAM)
PT (1) PT2379580E (OSRAM)
RS (1) RS53152B (OSRAM)
RU (1) RU2512396C2 (OSRAM)
SG (1) SG172299A1 (OSRAM)
SI (1) SI2379580T1 (OSRAM)
SM (1) SMT201400037B (OSRAM)
TW (1) TWI444198B (OSRAM)
WO (1) WO2010075215A1 (OSRAM)
ZA (1) ZA201104693B (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014515371A (ja) 2011-05-26 2014-06-30 キュービスト ファーマシューティカルズ， インコーポレイテッド Ｃｂ−１８３，３１５組成物および関連する方法
US10377699B2 (en) * 2013-11-06 2019-08-13 The University Of Hong Kong Daptomycin analogues and a method for the preparation of daptomycin or a daptomycin analogue
WO2015172047A1 (en) * 2014-05-08 2015-11-12 Merck Sharp & Dohme Corp. Cyclic peptide compounds and related methods, salts and compositions
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
US11667674B2 (en) * 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
MA44721B1 (fr) * 2016-04-22 2020-05-29 Astrazeneca Ab 151 85 Soedertaelje Inhibiteurs de mcl1 macrocycliques pour le traitement du cancer
US10098890B2 (en) 2016-10-29 2018-10-16 Cipla Limited Stable carfilzomib formulations
IT201600127655A1 (it) * 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
US10072045B1 (en) 2017-06-26 2018-09-11 Ramapo Pharmaceuticals, Inc. Antibacterial lipopeptides and methods for their preparation and use
US10526343B2 (en) 2018-03-26 2020-01-07 University Of Sharjah Heterocyclic systems and pharmaceutical applications thereof
RU2762182C1 (ru) * 2020-12-08 2021-12-16 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Гауземицины А и В - гликолипопептидные антибактериальные антибиотики и способ их получения

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854480A (en) 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
USRE32333E (en) 1978-10-16 1987-01-20 Eli Lilly And Company A-21978 Antibiotics and process for their production
USRE32455E (en) * 1978-10-16 1987-07-07 Eli Lilly And Company A-21978 antibiotics and process for their production
DE3376424D1 (en) * 1982-02-27 1988-06-01 Beecham Group Plc Antibacterial 1-normon-2-yl-heterocyclic compounds
US4524135A (en) * 1982-05-21 1985-06-18 Eli Lilly And Company A-21978C cyclic peptides
US4537717A (en) 1982-05-21 1985-08-27 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production
US4399067A (en) * 1982-05-21 1983-08-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4396543A (en) * 1982-05-21 1983-08-02 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4482487A (en) 1982-05-21 1984-11-13 Eli Lilly And Company A-21978C cyclic peptides
USRE32311E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
USRE32310E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
BG47040A3 (en) 1984-10-09 1990-04-16 Eli Lilly And Company Method for preparing of a- 21978 with cyclic peptidic derivatives
ZA883887B (en) * 1987-06-10 1990-02-28 Lilly Co Eli Chromatographic purification process
US5039660A (en) 1988-03-02 1991-08-13 Endocon, Inc. Partially fused peptide pellet
EP0460882B1 (en) * 1990-06-07 1996-07-24 Eli Lilly And Company Lipopeptide deacylase
WO1995005384A1 (en) 1993-08-13 1995-02-23 Smithkline Beecham Plc Derivatives of monic acids a and c having antibacterial, antimycoplasmatical, antifungal and herbicidal activity
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
DE69739532D1 (de) 1996-03-08 2009-09-24 Astellas Pharma Inc Prozess für die deacylierung von zyklischen lipopeptiden.
DE19807972A1 (de) 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
SI1115417T1 (sl) 1998-09-25 2006-08-31 Cubist Pharm Inc Uporaba daptomicina
WO2001033274A2 (en) 1999-11-03 2001-05-10 The Whitaker Corporation Optoelectric module for multi-fiber arrays
KR20020063228A (ko) 1999-12-15 2002-08-01 큐비스트 파마슈티컬즈 인코포레이티드 항균제로서 리포펩티드
EP2298790A1 (en) 1999-12-15 2011-03-23 Cubist Pharmaceuticals, Inc. Daptomycin analogs as antibacterial agents
EP1240182A2 (en) * 1999-12-15 2002-09-18 Cubist Pharmaceuticals, Inc. Daptomycin analogs and their use as antibacterial agents
US20060014674A1 (en) * 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
EP1423137B1 (en) 2001-08-06 2009-04-29 Cubist Pharmaceuticals, Inc. Lipopeptide stereoisomers, methods for preparing same, and useful intermediates
CA2587848A1 (en) * 2004-11-12 2006-10-19 Cubist Pharmaceuticals, Inc. Antiinfective lipopeptides

Also Published As

Publication number Publication date
US20140073558A1 (en) 2014-03-13
KR20110114592A (ko) 2011-10-19
JP2012513467A (ja) 2012-06-14
DK2379580T3 (da) 2014-01-20
RS53152B (sr) 2014-06-30
KR101717795B1 (ko) 2017-03-17
TWI444198B (zh) 2014-07-11
JP5670914B2 (ja) 2015-02-18
IL213638A0 (en) 2011-07-31
US20100184649A1 (en) 2010-07-22
CA2747965A1 (en) 2010-07-01
SMT201400037B (it) 2014-05-07
AU2009330245B2 (en) 2013-05-02
TW201028161A (en) 2010-08-01
AU2009330245C1 (en) 2013-09-26
EP2379580A1 (en) 2011-10-26
HRP20131170T1 (hr) 2014-01-03
HK1161886A1 (en) 2012-08-10
RU2512396C2 (ru) 2014-04-10
RU2011130278A (ru) 2013-01-27
BRPI0923567A2 (pt) 2016-09-27
US8507647B2 (en) 2013-08-13
AU2009330245A1 (en) 2011-08-04
CA2747965C (en) 2017-06-27
PT2379580E (pt) 2014-01-20
ZA201104693B (en) 2013-01-30
CN102325787A (zh) 2012-01-18
CN102325787B (zh) 2014-05-28
CY1114883T1 (el) 2016-12-14
EP2379580B1 (en) 2013-10-23
ES2442167T3 (es) 2014-02-10
SG172299A1 (en) 2011-07-28
AR074833A1 (es) 2011-02-16
MX2011006803A (es) 2011-09-06
NZ594019A (en) 2013-08-30
PL2379580T3 (pl) 2014-05-30
EP2674437A1 (en) 2013-12-18
WO2010075215A1 (en) 2010-07-01
US20150337013A1 (en) 2015-11-26

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