DK2133420T3 - Fremgangsmåde til fremstilling af L-aminosyrer under anvendelse af forbedrede stammer af familien Enterobacteriaceae - Google Patents
Fremgangsmåde til fremstilling af L-aminosyrer under anvendelse af forbedrede stammer af familien EnterobacteriaceaeInfo
- Publication number
- DK2133420T3 DK2133420T3 DK09162040.1T DK09162040T DK2133420T3 DK 2133420 T3 DK2133420 T3 DK 2133420T3 DK 09162040 T DK09162040 T DK 09162040T DK 2133420 T3 DK2133420 T3 DK 2133420T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- amino acids
- enterobacteriaceae family
- enhanced strains
- strains
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102008002309A DE102008002309A1 (de) | 2008-06-09 | 2008-06-09 | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2133420T3 true DK2133420T3 (da) | 2014-07-28 |
Family
ID=40812054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK09162040.1T DK2133420T3 (da) | 2008-06-09 | 2009-06-05 | Fremgangsmåde til fremstilling af L-aminosyrer under anvendelse af forbedrede stammer af familien Enterobacteriaceae |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2133420B1 (da) |
DE (1) | DE102008002309A1 (da) |
DK (1) | DK2133420T3 (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012223091A (ja) * | 2009-08-25 | 2012-11-15 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
WO2011038364A1 (en) | 2009-09-27 | 2011-03-31 | Opx Biotechnologies, Inc. | Method for producing 3-hydroxypropionic acid and other products |
WO2011094457A1 (en) * | 2010-01-27 | 2011-08-04 | Opx Biotechnologies, Inc. | Microorganism production of high-valve chemical products, and related compositions, methods and systems |
AU2013299414A1 (en) | 2012-08-10 | 2015-03-26 | Opx Biotechnologies, Inc. | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
US9447438B2 (en) | 2013-03-15 | 2016-09-20 | Cargill, Incorporated | Acetyl-coA carboxylases |
US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
JP6603658B2 (ja) | 2013-07-19 | 2019-11-06 | カーギル インコーポレイテッド | 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法 |
EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
CN110494566A (zh) | 2017-02-02 | 2019-11-22 | 嘉吉公司 | 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞 |
CN109554322B (zh) * | 2018-12-03 | 2020-08-04 | 江南大学 | 一种高产l-苏氨酸的重组大肠杆菌及其构建方法 |
CN109852572B (zh) * | 2019-01-28 | 2021-05-28 | 江南大学 | 一种敲除大肠杆菌pts系统提高l-苏氨酸产量的方法 |
Family Cites Families (53)
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SU875663A1 (ru) | 1978-06-30 | 1982-09-15 | Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Штаммы е.coLI ВНИИГенетика VL 334 @ N6 и ВНИИГенетика VL 334 @ N7-продуценты L-треонина и способ их получени |
SU943282A1 (ru) | 1979-07-13 | 1982-07-15 | Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Способ получени L-треонина |
JPS5618596A (en) | 1979-07-23 | 1981-02-21 | Ajinomoto Co Inc | Production of l-lysine through fermentation process |
JPS5685289A (en) | 1979-12-13 | 1981-07-11 | Ajinomoto Co Inc | Preparation of l-valine by fermentation |
US4371614A (en) | 1980-08-22 | 1983-02-01 | Ajinomoto Co., Inc. | E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan |
FR2511032B1 (fr) | 1981-08-07 | 1985-08-09 | Centre Nat Rech Scient | Nouveaux plasmides et souches bacteriennes transformees et leur application a la synthese de lysine |
CA1226541A (en) | 1984-01-13 | 1987-09-08 | Stauffer Chemical Company | Mutant strain deficient in l-serine deaminase activity |
WO1987001130A1 (en) | 1985-08-15 | 1987-02-26 | Stauffer Chemical Company | Tryptophan producing microorganism |
JPS6437295A (en) | 1987-07-31 | 1989-02-07 | Kyowa Hakko Kogyo Kk | Production of l-threonine by fermentation |
US4990487A (en) | 1988-03-11 | 1991-02-05 | The University Of Tokyo | Superconductive optoelectronic devices |
WO1990004636A1 (en) | 1988-10-25 | 1990-05-03 | Vsesojuzny Nauchno-Issledovatelsky Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov (Vniigenetika) | Strain of bacteria escherichia coli, producer of l-threonine |
EP0745671B1 (en) | 1990-11-30 | 2003-11-12 | Ajinomoto Co., Inc. | Recombinant DNA sequences encoding feedback inhibition released enzymes, plasmids comprising the recombinant DNA sequences, transformed microorganisms useful in the production of aromatic amino acids, and a process for preparing aromatic amino acids by fermentation |
US5168056A (en) | 1991-02-08 | 1992-12-01 | Purdue Research Foundation | Enhanced production of common aromatic pathway compounds |
JP3036930B2 (ja) | 1991-11-11 | 2000-04-24 | 協和醗酵工業株式会社 | 発酵法によるl−イソロイシンの製造法 |
DE4232468A1 (de) | 1992-09-28 | 1994-03-31 | Consortium Elektrochem Ind | Mikroorganismen für die Produktion von Tryptophan und Verfahren zu ihrer Herstellung |
DE69219775T3 (de) | 1992-10-14 | 2004-08-05 | Ajinomoto Co., Inc. | Neuartiges L-threoninproduzierendes Mikrobakterium und eine Herstellungsmethode für L-Threonin |
JP3131311B2 (ja) | 1992-10-27 | 2001-01-31 | 協和醗酵工業株式会社 | 発酵法によるl−イソロイシンの製造法 |
EP0733712B1 (en) | 1993-10-28 | 2001-12-12 | Ajinomoto Co., Inc. | Process for producing substance |
DE69534848T2 (de) | 1994-09-16 | 2006-11-23 | The Texas A & M University System, College Station | Mikroorganismen und Verfahren zur Überproduktion von DAHP mittels klonierten PPSGens |
JP3717970B2 (ja) | 1995-05-31 | 2005-11-16 | 協和醗酵工業株式会社 | 発酵法によるl−イソロイシンの製造法 |
JP4032441B2 (ja) | 1995-08-30 | 2008-01-16 | 味の素株式会社 | L−アミノ酸の製造方法 |
GB2304718B (en) | 1995-09-05 | 2000-01-19 | Degussa | The production of tryptophan by the bacterium escherichia coli |
US5763230A (en) | 1996-03-22 | 1998-06-09 | Triple-A B.V. P/A Produkschap Voor Veevoedor | Amino acid fermentation processes |
US5939295A (en) | 1996-03-29 | 1999-08-17 | Archer Daniels Midland Company | Production of tryptophan by microorganisms |
US5939307A (en) | 1996-07-30 | 1999-08-17 | The Archer-Daniels-Midland Company | Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production |
JP2002508921A (ja) | 1997-10-04 | 2002-03-26 | フォルシュングスツェントルム・ユーリッヒ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | アスパラギン酸−及び(又は)グルタミン酸系アミノ酸の微生物による産生方法及びこの方法で使用可能な剤 |
KR100270510B1 (ko) | 1998-08-14 | 2000-11-01 | 고두모 | 신규 미생물 및 이를 이용한 엘- 쓰레오닌의 제조방법 |
KR100270509B1 (ko) | 1998-08-14 | 2000-11-01 | 고두모 | 신규 미생물 및 이를 이용한 엘- 쓰레오닌의 제조방법 |
RU2148642C1 (ru) | 1998-12-23 | 2000-05-10 | ЗАО "Научно-исследовательский институт АДЖИНОМОТО-Генетика" (ЗАО "АГРИ") | Фрагмент днк rhtc, кодирующий синтез белка rhtc, придающего повышенную устойчивость к l-треонину бактериям escherichia coli, и способ получения l-аминокислоты |
DE19907347A1 (de) | 1999-02-20 | 2000-08-24 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
JP2003204788A (ja) | 1999-07-19 | 2003-07-22 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
AU5530699A (en) | 1999-08-26 | 2001-03-19 | Daesang Corporation | Microorganisms and methods for producing threonine |
RU2212447C2 (ru) | 2000-04-26 | 2003-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты) |
MXPA02008416A (es) | 2000-05-27 | 2002-12-13 | Degussa | Proceso para la preparacion fermentativa de l-treonina. |
WO2002018543A2 (en) | 2000-08-31 | 2002-03-07 | Degussa Ag | Fermentation process for the preparation of l-threonine |
US7220571B2 (en) | 2000-09-28 | 2007-05-22 | Archer-Daniels-Midland Company | Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation |
MXPA03002639A (es) | 2000-09-30 | 2003-06-19 | Degussa | Proceso de fermentacion para la preparacion de l-aminoacidos utilizando cepas de la familia enterobacteriaceae. |
AU2002215910A1 (en) | 2000-11-04 | 2002-05-15 | Degussa Ag | Process for the fermentative preparation of l-amino acids using strains of the enterobacteriaceae family |
KR100397423B1 (ko) | 2001-02-13 | 2003-09-13 | 씨제이 주식회사 | L-쓰레오닌의 제조방법 |
DE10116518A1 (de) | 2001-04-03 | 2002-10-17 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
ATE408691T1 (de) | 2001-07-06 | 2008-10-15 | Evonik Degussa Gmbh | Verfahren zur herstellung von l-aminosäuren durch enterobacteriaceae-stämmen mit verstärkter expression des mop-b |
ATE334221T1 (de) | 2001-07-11 | 2006-08-15 | Degussa | Verfahren zur herstellung von l-threonin unter verwendung von stämmen der familie enterobacteriaceae |
WO2003008616A2 (en) | 2001-07-18 | 2003-01-30 | Degussa Ag | PROCESS FOR THE PREPARATION OF L-AMINO ACIDS USING STRAINS OF THE ENTEROBACTERIACEAE FAMILY WHICH CONTAIN AN ATTENUATED aceK GENE |
DE60233573D1 (de) | 2001-07-18 | 2009-10-15 | Evonik Degussa Gmbh | Verfahren zur herstellung von l-aminosäuren durch enterobakteriaceae-stämmen mit verstärkter exprimierung des rsea-gens |
US7319026B2 (en) | 2002-03-07 | 2008-01-15 | Degussa Ag | Amino acid-producing bacteria and a process for preparing L-amino acids |
RU2268300C2 (ru) | 2003-04-07 | 2006-01-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA |
EP1649031A1 (en) | 2003-08-01 | 2006-04-26 | Degussa AG | Process for the preparation of l-threonine |
EP1649033A1 (en) | 2003-08-01 | 2006-04-26 | Degussa AG | Process for the preparation of l-threonine |
DE102004028859A1 (de) | 2003-08-01 | 2005-02-24 | Degussa Ag | Verfahren zur Herstellung von L-Threonin |
EP1649032A1 (en) | 2003-08-01 | 2006-04-26 | Degussa AG | Process for the preparation of l-threonine |
DE102004029639A1 (de) | 2003-08-12 | 2005-03-24 | Degussa Ag | Verfahren zur Herstellung von L-Threonin |
DE102004037572A1 (de) * | 2004-08-03 | 2006-02-23 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
RU2006143864A (ru) * | 2006-12-12 | 2008-06-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНОВ cynT, cynS, cynX, ИЛИ cynR, ИЛИ ИХ КОМБИНАЦИИ |
-
2008
- 2008-06-09 DE DE102008002309A patent/DE102008002309A1/de not_active Withdrawn
-
2009
- 2009-06-05 DK DK09162040.1T patent/DK2133420T3/da active
- 2009-06-05 EP EP09162040.1A patent/EP2133420B1/de not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
DE102008002309A1 (de) | 2009-12-10 |
EP2133420A1 (de) | 2009-12-16 |
EP2133420B1 (de) | 2014-04-23 |
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