DK2061803T3 - Fremgangsmåde til oprensning af fc-holdige proteiner - Google Patents

Fremgangsmåde til oprensning af fc-holdige proteiner Download PDF

Info

Publication number
DK2061803T3
DK2061803T3 DK07802925T DK07802925T DK2061803T3 DK 2061803 T3 DK2061803 T3 DK 2061803T3 DK 07802925 T DK07802925 T DK 07802925T DK 07802925 T DK07802925 T DK 07802925T DK 2061803 T3 DK2061803 T3 DK 2061803T3
Authority
DK
Denmark
Prior art keywords
cleaning
procedure
containing proteins
proteins
Prior art date
Application number
DK07802925T
Other languages
English (en)
Other versions
DK2061803T4 (da
Inventor
Alex Eon-Duval
Alain Lamproye
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38610939&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2061803(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of DK2061803T3 publication Critical patent/DK2061803T3/da
Application granted granted Critical
Publication of DK2061803T4 publication Critical patent/DK2061803T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
DK07802925.3T 2006-08-28 2007-08-27 Fremgangsmåde til oprensning af fc-holdige proteiner DK2061803T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06119611 2006-08-28
US84254206P 2006-09-06 2006-09-06
PCT/EP2007/058887 WO2008025748A1 (en) 2006-08-28 2007-08-27 Process for the purification of fc-containing proteins

Publications (2)

Publication Number Publication Date
DK2061803T3 true DK2061803T3 (da) 2019-11-18
DK2061803T4 DK2061803T4 (da) 2022-12-05

Family

ID=38610939

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07802925.3T DK2061803T4 (da) 2006-08-28 2007-08-27 Fremgangsmåde til oprensning af fc-holdige proteiner

Country Status (21)

Country Link
US (1) US8513393B2 (da)
EP (1) EP2061803B2 (da)
JP (1) JP2010501623A (da)
KR (1) KR101770312B1 (da)
AR (1) AR062570A1 (da)
AU (1) AU2007291283B2 (da)
CA (1) CA2661748C (da)
DK (1) DK2061803T4 (da)
EA (1) EA017152B1 (da)
ES (1) ES2755386T5 (da)
FI (1) FI2061803T4 (da)
HK (1) HK1131400A1 (da)
HU (1) HUE045898T2 (da)
IL (1) IL197220A (da)
LT (1) LT2061803T (da)
MX (1) MX2009002014A (da)
PL (1) PL2061803T5 (da)
PT (1) PT2061803T (da)
SI (1) SI2061803T2 (da)
UA (1) UA99262C2 (da)
WO (1) WO2008025748A1 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR058568A1 (es) 2005-12-20 2008-02-13 Bristol Myers Squibb Co Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo
PL2253644T3 (pl) 2005-12-20 2014-04-30 Bristol Myers Squibb Co Kompozycje i sposoby wytwarzania kompozycji
PT2061803T (pt) † 2006-08-28 2019-11-21 Ares Trading Sa Processo de purificação de proteinas contendo fc
PT2215117E (pt) * 2007-10-30 2015-04-01 Genentech Inc Purificação de anticorpo por cromatografia de troca de catiões
TW201030016A (en) * 2008-10-20 2010-08-16 Abbott Lab Antibodies that bind to IL-18 and methods of purifying the same
NZ592097A (en) * 2008-10-20 2013-01-25 Abbott Lab Viral inactivation during purification of il-12 and il-18 antibodies
US20100111853A1 (en) * 2008-10-20 2010-05-06 Abbott Laboratories, Inc. Antibodies that bind to il-12 and methods of purifying the same
CA2911256A1 (en) * 2008-10-20 2010-12-09 Robert K. Hickman Isolation and purification of antibodies using protein a affinity chromatography
US8536316B2 (en) 2009-08-07 2013-09-17 Emd Millipore Corporation Methods for purifying a target protein from one or more impurities in a sample
CA2784278C (en) 2009-12-18 2019-02-26 Novartis Ag Wash solution and method for affinity chromatography
WO2011088225A1 (en) 2010-01-15 2011-07-21 Bio-Rad Laboratories, Inc. Surface neutralization of apatite
US8895707B2 (en) * 2010-08-18 2014-11-25 Bio-Rad Laboratories, Inc. Elution of proteins from hydroxyapatite resins without resin deterioration
JP5798307B2 (ja) * 2010-09-03 2015-10-21 国立大学法人名古屋大学 グロボトリアオシルセラミドを特異的に認識するモノクローナル抗体及びその作製法
JP5838221B2 (ja) 2010-12-21 2016-01-06 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト アイソフォーム濃縮抗体調製物及びこれを得る方法
CA2825651C (en) 2011-02-02 2020-03-24 Bio-Rad Laboratories, Inc. Apatite surface neutralization with alkali solutions
ES2784628T3 (es) 2011-03-29 2020-09-29 Glaxosmithkline Llc Sistema de tampón para purificación de proteína
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
WO2013180933A1 (en) 2012-05-30 2013-12-05 Bio-Rad Laboratories, Inc. In situ restoration of apatite-based chromatography resins
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
EP3155009A1 (en) * 2014-06-13 2017-04-19 Lupin Limited Process for the purification of tnfr:fc fusion protein
WO2015200299A2 (en) 2014-06-23 2015-12-30 Bio-Rad Laboratories, Inc. Apatite in-situ restoration
US9802822B2 (en) 2014-06-23 2017-10-31 Bio-Rad Laboratories, Inc. Apatite pretreatment
EP2975050B1 (en) * 2014-07-18 2019-05-29 Sandoz Ag Quantification of misfolded TNFR2:Fc
BR112017018365A2 (pt) * 2015-03-13 2018-04-10 Bristol-Myers Squibb Company uso de lavagens alcalinas durante cromatografia para remoção de impurezas
CN116903727A (zh) 2020-05-08 2023-10-20 高山免疫科学股份有限公司 具有和不具有t细胞抑制蛋白的april和baff抑制性免疫调节蛋白及其使用方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU630497B2 (en) 1989-09-05 1992-10-29 Immunex Corporation Tumor necrosis factor-alpha and -beta receptors
US5447851B1 (en) * 1992-04-02 1999-07-06 Univ Texas System Board Of Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells
WO1994006476A1 (en) 1992-09-15 1994-03-31 Immunex Corporation Method of treating tnf-dependent inflammation using tumor necrosis factor antagonists
DK0659767T4 (da) * 1993-12-27 2003-02-10 Zlb Bioplasma Ag Fremgangsmåde til fremstilling af et koncentrat af anti-D-immunoglobulin G og et farmaceutisk præparat, som indeholder dette
NZ312285A (en) 1995-06-08 2001-04-27 Immunex Corp TNF-alpha converting enzyme (TACE)
US6406901B1 (en) * 1995-06-08 2002-06-18 Immunex Corporation TNF-a converting enzyme
US5969102A (en) 1997-03-03 1999-10-19 St. Jude Children's Research Hospital Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof
IL121900A (en) 1997-10-07 2001-12-23 Omrix Biopharmaceuticals Ltd A method for the purification of immunoglobulins
DE69936946T2 (de) 1998-05-06 2008-05-15 Genentech, Inc., South San Francisco Reinigung von Antikörpern durch Ionenaustauschchromatographie
JP2002517406A (ja) 1998-06-01 2002-06-18 ジェネンテック・インコーポレーテッド イオン交換クロマトグラフィーの使用による、凝集体からのタンパク質モノマーの分離
SK288128B6 (sk) 1998-06-09 2013-10-02 Csl Behring Ag Process for purifying immunoglobulin G (IgG), liquid immunoglobulin product and use thereof for the preparation of a medicament
ATE437227T1 (de) 1999-01-07 2009-08-15 Zymogenetics Inc Verfahren zur therapeutischen verwendung von löslichen rezeptoren br43x2
DE19955558C2 (de) 1999-11-18 2003-03-20 Stefan Kochanek Permanente Amniozyten-Zelllinie, ihre Herstellung und Verwendung zur Herstellung von Gentransfervektoren
MXPA02011130A (es) * 2000-05-12 2003-03-10 Amgen Inc Metodos y composiciones de materia que se refieren a april/g70, bcma, blys/agp-3, y taci.
RS20120253A1 (en) * 2001-05-24 2013-02-28 Zymogenetics Inc. TACI-IMUNOGLOBULINSKI PROTEIN FUNCTIONS
CA2451955C (en) 2001-06-26 2015-09-29 Abgenix, Inc. Antibodies to opgl
CA2469815C (en) 2001-12-21 2011-05-03 Immunex Corporation Methods for purifying protein
US7323553B2 (en) 2002-04-26 2008-01-29 Genentech, Inc. Non-affinity purification of proteins
ES2626268T3 (es) 2002-09-11 2017-07-24 Chugai Seiyaku Kabushiki Kaisha Método de purificación de proteínas
HUE033623T2 (en) 2002-09-11 2017-12-28 Genentech Inc protein purification
DK1601697T3 (da) * 2003-02-28 2007-10-01 Lonza Biologics Plc Oprensning af antistof ved protein A- og ionbytningskromatografi
WO2004087761A1 (ja) 2003-03-31 2004-10-14 Kirin Beer Kabushiki Kaisha ヒトモノクローナル抗体およびヒトポリクローナル抗体の精製
TWI353991B (en) * 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
BRPI0415887B1 (pt) 2003-10-27 2021-01-26 Wyeth métodos para a remoção de agregados de elevado peso molecular utilizando cromatografia de hidroxiapatita
BRPI0406605B8 (pt) * 2003-11-13 2021-05-25 Hanmi Holdings Co Ltd conjugado de proteína, método para a preparação do mesmo e composição farmacêutica para intensificar a duração e estabilidade in vivo de um polipeptídeo fisiologicamente ativo
JP2007538006A (ja) * 2004-04-14 2007-12-27 エフ．ホフマン−ラ　ロシュ　アーゲー 精製インターロイキン１５／Ｆｃ融合タンパク質とその調整
PL1869065T3 (pl) 2005-03-11 2020-09-21 Wyeth Llc Sposób prowadzenia chromatografii podziałowej ze słabym wiązaniem
US8129508B2 (en) * 2005-04-11 2012-03-06 Medarex, Inc. Protein purification using HCIC and ion exchange chromatography
EP2388274A1 (en) * 2005-06-17 2011-11-23 Janssen Alzheimer Immunotherapy Methods of purifying anti A Beta antibodies
US20100234577A1 (en) 2006-06-14 2010-09-16 Smithkline Beecham Corporation Methods for purifying antibodies using ceramic hydroxyapatite
PT2061803T (pt) † 2006-08-28 2019-11-21 Ares Trading Sa Processo de purificação de proteinas contendo fc
EP2114984A2 (en) * 2007-01-17 2009-11-11 Merck Serono S.A. Process for the purification of fc-containing proteins

Also Published As

Publication number Publication date
ES2755386T3 (es) 2020-04-22
IL197220A0 (en) 2009-12-24
ES2755386T5 (es) 2023-04-05
EA017152B1 (ru) 2012-10-30
US20100190961A1 (en) 2010-07-29
KR20090057296A (ko) 2009-06-04
UA99262C2 (uk) 2012-08-10
JP2010501623A (ja) 2010-01-21
EP2061803B1 (en) 2019-08-14
HK1131400A1 (en) 2010-01-22
HUE045898T2 (hu) 2020-01-28
WO2008025748A1 (en) 2008-03-06
CA2661748C (en) 2016-02-09
AU2007291283A1 (en) 2008-03-06
DK2061803T4 (da) 2022-12-05
MX2009002014A (es) 2009-03-09
SI2061803T2 (sl) 2023-01-31
LT2061803T (lt) 2019-11-25
AU2007291283B2 (en) 2012-09-20
EP2061803B2 (en) 2022-11-16
PT2061803T (pt) 2019-11-21
EA200970231A1 (ru) 2009-08-28
IL197220A (en) 2013-06-27
AR062570A1 (es) 2008-11-19
KR101770312B1 (ko) 2017-08-22
PL2061803T3 (pl) 2020-02-28
CA2661748A1 (en) 2008-03-06
PL2061803T5 (pl) 2023-03-27
FI2061803T4 (fi) 2023-03-14
US8513393B2 (en) 2013-08-20
SI2061803T1 (sl) 2019-12-31
EP2061803A1 (en) 2009-05-27

Similar Documents

Publication Publication Date Title
DK2061803T3 (da) Fremgangsmåde til oprensning af fc-holdige proteiner
CY2016029I2 (el) Πρωτεϊνες συνδεσης αντιγονου προς προπρωτεϊνη κονβερτασης σουμπτιλισινης κεχιν τυπου 9(pcsk9)
DK2046826T3 (da) Exendin-fusionsproteiner
DK2012940T3 (da) Hidtil ukendt rengøringsfremgangsmåde
DK1999154T3 (da) Fremstillede heterodimere proteindomæner
DK3118221T3 (da) Proteiner
DK1748077T3 (da) Fremgangsmåde til fremstilling af protein
DK1941026T3 (da) Fremgangsmåder til fremstilling af protein under anvendelse af anti-senescensforbindelser
DK2066695T3 (da) Anti-myostatin-antistoffer
DK2180938T3 (da) Fremgangsmåde til rengøring af røggas
DK2086944T3 (da) Fremgangsmåde til fremstilling af difluormethylpyrazolylcarboxylater
DK2035166T3 (da) Fremgangsmåde til fremstilling af beholdere
BRPI0819210A2 (pt) Anticorpos de proteína g anti-rsv
DK1852430T3 (da) Fremgangsmåde til fremstilling af proanthocyanidinoligomer
BRPI0716744A2 (pt) proteínas de fusão de albumina
DK2054711T3 (da) Fremgangsmåde til fremstilling af mikroarrays
DK2044002T3 (da) Fremgangsmåde til fremstilling af 3-substituerede 2-amino-5-halobenzamider
CR10161A (es) Inmunoglobulinas
BRPI0814971A2 (pt) Proteína
DE602007008787D1 (de) Spannvorrichtung
FI7098U1 (fi) Kaidejärjestelmä
DK2061746T3 (da) Fremgangsmåde til fremstilling af diestere
FI20065363A0 (fi) Erotusmenetelmä
DK2020845T3 (da) Fremgangsmåde til høstning
DE112007001674A5 (de) Spannvorrichtung