LT2061803T - Fc turinčių baltymų gryninimo būdas - Google Patents
Fc turinčių baltymų gryninimo būdasInfo
- Publication number
- LT2061803T LT2061803T LT07802925T LT07802925T LT2061803T LT 2061803 T LT2061803 T LT 2061803T LT 07802925 T LT07802925 T LT 07802925T LT 07802925 T LT07802925 T LT 07802925T LT 2061803 T LT2061803 T LT 2061803T
- Authority
- LT
- Lithuania
- Prior art keywords
- purification
- containing proteins
- proteins
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06119611 | 2006-08-28 | ||
US84254206P | 2006-09-06 | 2006-09-06 | |
PCT/EP2007/058887 WO2008025748A1 (en) | 2006-08-28 | 2007-08-27 | Process for the purification of fc-containing proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2061803T true LT2061803T (lt) | 2019-11-25 |
Family
ID=38610939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LT07802925T LT2061803T (lt) | 2006-08-28 | 2007-08-27 | Fc turinčių baltymų gryninimo būdas |
Country Status (21)
Country | Link |
---|---|
US (1) | US8513393B2 (lt) |
EP (1) | EP2061803B2 (lt) |
JP (1) | JP2010501623A (lt) |
KR (1) | KR101770312B1 (lt) |
AR (1) | AR062570A1 (lt) |
AU (1) | AU2007291283B2 (lt) |
CA (1) | CA2661748C (lt) |
DK (1) | DK2061803T4 (lt) |
EA (1) | EA017152B1 (lt) |
ES (1) | ES2755386T5 (lt) |
FI (1) | FI2061803T4 (lt) |
HK (1) | HK1131400A1 (lt) |
HU (1) | HUE045898T2 (lt) |
IL (1) | IL197220A (lt) |
LT (1) | LT2061803T (lt) |
MX (1) | MX2009002014A (lt) |
PL (1) | PL2061803T5 (lt) |
PT (1) | PT2061803T (lt) |
SI (1) | SI2061803T2 (lt) |
UA (1) | UA99262C2 (lt) |
WO (1) | WO2008025748A1 (lt) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR058568A1 (es) | 2005-12-20 | 2008-02-13 | Bristol Myers Squibb Co | Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo |
WO2007076032A2 (en) | 2005-12-20 | 2007-07-05 | Bristol-Myers Squibb Company | Compositions and methods for producing a composition |
DK2061803T4 (da) † | 2006-08-28 | 2022-12-05 | Ares Trading Sa | Fremgangsmåde til oprensning af fc-holdige proteiner |
KR101241486B1 (ko) * | 2007-10-30 | 2013-03-15 | 제넨테크, 인크. | 양이온 교환 크로마토그래피에 의한 항체 정제 |
TW201028433A (en) * | 2008-10-20 | 2010-08-01 | Abbott Lab | Viral inactivation during purification of antibodies |
EP2346901A1 (en) * | 2008-10-20 | 2011-07-27 | Abbott Laboratories | Antibodies that bind to il-18 and methods of purifying the same |
WO2010141039A1 (en) | 2008-10-20 | 2010-12-09 | Abbott Laboratories | Isolation and purification of antibodies using protein a affinity chromatography |
RU2011120178A (ru) * | 2008-10-20 | 2012-11-27 | Эбботт Лэборетриз | Антитела, которые связываются с il-12, и способы их очистки |
CN107188960A (zh) * | 2009-08-07 | 2017-09-22 | Emd密理博公司 | 从样品的一或多种杂质中纯化靶蛋白的方法 |
RU2564569C2 (ru) | 2009-12-18 | 2015-10-10 | Новартис Аг | Промывочный раствор и способ промывки для аффинной хроматографии |
WO2011088225A1 (en) | 2010-01-15 | 2011-07-21 | Bio-Rad Laboratories, Inc. | Surface neutralization of apatite |
US8895707B2 (en) * | 2010-08-18 | 2014-11-25 | Bio-Rad Laboratories, Inc. | Elution of proteins from hydroxyapatite resins without resin deterioration |
JP5798307B2 (ja) * | 2010-09-03 | 2015-10-21 | 国立大学法人名古屋大学 | グロボトリアオシルセラミドを特異的に認識するモノクローナル抗体及びその作製法 |
EP2655412B1 (en) | 2010-12-21 | 2018-01-17 | F. Hoffmann-La Roche AG | Isoform enriched antibody preparation and method for obtaining it |
EP2670704B1 (en) | 2011-02-02 | 2018-12-12 | Bio-Rad Laboratories, Inc. | Apatite surface neutralization with alkali solutions |
CN103547589A (zh) | 2011-03-29 | 2014-01-29 | 葛兰素史密斯克莱有限责任公司 | 用于蛋白纯化的缓冲液体系 |
SG10201701224UA (en) * | 2012-03-12 | 2017-04-27 | Merck Patent Gmbh | Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode |
WO2013180933A1 (en) | 2012-05-30 | 2013-12-05 | Bio-Rad Laboratories, Inc. | In situ restoration of apatite-based chromatography resins |
EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
JP6747985B2 (ja) * | 2014-06-13 | 2020-08-26 | ルピン アトランティス ホールディングス エスエー | TNFR:Fc融合タンパク質の精製方法 |
CN105407917B (zh) | 2014-06-23 | 2021-07-06 | 生物辐射实验室股份有限公司 | 磷灰石原位恢复 |
US9802822B2 (en) | 2014-06-23 | 2017-10-31 | Bio-Rad Laboratories, Inc. | Apatite pretreatment |
ES2733298T3 (es) * | 2014-07-18 | 2019-11-28 | Sandoz Ag | Cuantificación de TNFR2:Fc plegado erróneamente |
SG10201908027QA (en) * | 2015-03-13 | 2019-10-30 | Bristol Myers Squibb Co | Use of alkaline washes during chromatography to remove impurities |
PE20230494A1 (es) | 2020-05-08 | 2023-03-23 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras inhibidoras de april y baff y metodos de uso de las mismas |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2065346C (en) | 1989-09-05 | 2005-03-29 | Craig A. Smith | Tumor necrosis factor-.alpha. and-.beta. receptors |
US5447851B1 (en) * | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
EP0620739A4 (en) | 1992-09-15 | 1997-01-15 | Immunex Corp | Method of treating tnf-dependent inflammation using tumor necrosis factor antagonists. |
ES2129076T5 (es) * | 1993-12-27 | 2003-05-16 | Zlb Bioplasma Ag | Procedimiento para la preparacion de un concentrado de inmunoglobulina g anti-d y composicion farmaceutica que lo contiene. |
US6406901B1 (en) * | 1995-06-08 | 2002-06-18 | Immunex Corporation | TNF-a converting enzyme |
ATE274346T1 (de) | 1995-06-08 | 2004-09-15 | Immunex Corp | Tnf-alpha konvertierendes enzym |
US5969102A (en) | 1997-03-03 | 1999-10-19 | St. Jude Children's Research Hospital | Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof |
IL121900A (en) | 1997-10-07 | 2001-12-23 | Omrix Biopharmaceuticals Ltd | A method for the purification of immunoglobulins |
DE69907439T3 (de) * | 1998-05-06 | 2014-01-02 | Genentech, Inc. | Reinigung von proteinen durch ionenaustauschchromatographie |
ATE274522T1 (de) | 1998-06-01 | 2004-09-15 | Genentech Inc | Abtrennung von antikörper-monomeren von deren multimeren mittels ionaustausch-chromatographie |
EP2270044B1 (en) | 1998-06-09 | 2014-11-05 | CSL Behring AG | Liquid immunoglobulin G (lgG) product |
NZ512753A (en) | 1999-01-07 | 2003-10-31 | Zymogenetics Inc | Soluble receptor BR43x2 related proteins useful for inhibiting ztnf4 |
DE19955558C2 (de) | 1999-11-18 | 2003-03-20 | Stefan Kochanek | Permanente Amniozyten-Zelllinie, ihre Herstellung und Verwendung zur Herstellung von Gentransfervektoren |
US20020086018A1 (en) * | 2000-05-12 | 2002-07-04 | Theill Lars Eyde | Methods and compositions of matter concerning APRIL/G70, BCMA, BLYS/AGP-3, and TACI |
EA007275B1 (ru) | 2001-05-24 | 2006-08-25 | Займодженетикс, Инк. | Слитые белки taci-иммуноглобулина |
CN103232539B (zh) | 2001-06-26 | 2015-06-03 | 安姆根弗里蒙特公司 | 抗opgl抗体 |
AU2002359816B2 (en) | 2001-12-21 | 2006-07-13 | Immunex Corporation | Methods for purifying protein |
HUE025101T2 (en) | 2002-04-26 | 2016-02-29 | Genentech Inc | Purification of proteins other than affinity purification |
ES2626268T3 (es) | 2002-09-11 | 2017-07-24 | Chugai Seiyaku Kabushiki Kaisha | Método de purificación de proteínas |
IL262513B (en) | 2002-09-11 | 2022-09-01 | Genentech Inc | Cleaning proteins |
DK1601697T3 (da) * | 2003-02-28 | 2007-10-01 | Lonza Biologics Plc | Oprensning af antistof ved protein A- og ionbytningskromatografi |
JPWO2004087761A1 (ja) * | 2003-03-31 | 2006-07-27 | 麒麟麦酒株式会社 | ヒトモノクローナル抗体およびヒトポリクローナル抗体の精製 |
TWI353991B (en) * | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
EP2336172B1 (en) | 2003-10-27 | 2014-12-10 | Wyeth LLC | Removal of high molecular weight aggregates using hydroxyapatite chromatography |
US8846874B2 (en) * | 2003-11-13 | 2014-09-30 | Hanmi Science Co., Ltd | IgG Fc fragment for a drug carrier and method for the preparation thereof |
WO2005100394A2 (en) | 2004-04-14 | 2005-10-27 | F. Hoffmann-La Roche Ag | PURIFIED INTERLEUKIN-15/Fc FUSION PROTEIN AND PREPARATION THEREOF |
KR101482791B1 (ko) | 2005-03-11 | 2015-01-21 | 와이어쓰 엘엘씨 | 약한 분배성 크로마토그래피법 |
NZ562949A (en) * | 2005-04-11 | 2009-05-31 | Medarex Inc | Protein purification using HCIC and ion exchange chromatography |
SG162806A1 (en) * | 2005-06-17 | 2010-07-29 | Elan Pharma Int Ltd | Methods of purifying anti a beta antibodies |
WO2009017491A1 (en) | 2006-06-14 | 2009-02-05 | Smithkline Beecham Corporation | Methods for purifying antibodies using ceramic hydroxyapatite |
DK2061803T4 (da) † | 2006-08-28 | 2022-12-05 | Ares Trading Sa | Fremgangsmåde til oprensning af fc-holdige proteiner |
CA2673771A1 (en) * | 2007-01-17 | 2008-07-24 | Merck Serono S.A. | Process for the purification of fc-containing proteins |
-
2007
- 2007-08-27 DK DK07802925.3T patent/DK2061803T4/da active
- 2007-08-27 MX MX2009002014A patent/MX2009002014A/es active IP Right Grant
- 2007-08-27 US US12/377,122 patent/US8513393B2/en active Active
- 2007-08-27 JP JP2009526068A patent/JP2010501623A/ja active Pending
- 2007-08-27 CA CA2661748A patent/CA2661748C/en active Active
- 2007-08-27 PL PL07802925.3T patent/PL2061803T5/pl unknown
- 2007-08-27 ES ES07802925T patent/ES2755386T5/es active Active
- 2007-08-27 EP EP07802925.3A patent/EP2061803B2/en active Active
- 2007-08-27 PT PT78029253T patent/PT2061803T/pt unknown
- 2007-08-27 HU HUE07802925A patent/HUE045898T2/hu unknown
- 2007-08-27 KR KR1020097006443A patent/KR101770312B1/ko active IP Right Grant
- 2007-08-27 UA UAA200902854A patent/UA99262C2/uk unknown
- 2007-08-27 EA EA200970231A patent/EA017152B1/ru not_active IP Right Cessation
- 2007-08-27 FI FIEP07802925.3T patent/FI2061803T4/fi active
- 2007-08-27 SI SI200732135T patent/SI2061803T2/sl unknown
- 2007-08-27 WO PCT/EP2007/058887 patent/WO2008025748A1/en active Application Filing
- 2007-08-27 AU AU2007291283A patent/AU2007291283B2/en active Active
- 2007-08-27 LT LT07802925T patent/LT2061803T/lt unknown
- 2007-08-28 AR ARP070103817A patent/AR062570A1/es not_active Application Discontinuation
-
2009
- 2009-02-24 IL IL197220A patent/IL197220A/en active IP Right Grant
- 2009-12-03 HK HK09111377.1A patent/HK1131400A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2661748C (en) | 2016-02-09 |
KR101770312B1 (ko) | 2017-08-22 |
KR20090057296A (ko) | 2009-06-04 |
EP2061803B2 (en) | 2022-11-16 |
DK2061803T3 (da) | 2019-11-18 |
JP2010501623A (ja) | 2010-01-21 |
ES2755386T5 (es) | 2023-04-05 |
EP2061803B1 (en) | 2019-08-14 |
IL197220A0 (en) | 2009-12-24 |
WO2008025748A1 (en) | 2008-03-06 |
MX2009002014A (es) | 2009-03-09 |
SI2061803T1 (sl) | 2019-12-31 |
IL197220A (en) | 2013-06-27 |
FI2061803T4 (fi) | 2023-03-14 |
HUE045898T2 (hu) | 2020-01-28 |
US20100190961A1 (en) | 2010-07-29 |
PT2061803T (pt) | 2019-11-21 |
ES2755386T3 (es) | 2020-04-22 |
EA200970231A1 (ru) | 2009-08-28 |
SI2061803T2 (sl) | 2023-01-31 |
AU2007291283B2 (en) | 2012-09-20 |
EA017152B1 (ru) | 2012-10-30 |
AR062570A1 (es) | 2008-11-19 |
PL2061803T5 (pl) | 2023-03-27 |
US8513393B2 (en) | 2013-08-20 |
EP2061803A1 (en) | 2009-05-27 |
UA99262C2 (uk) | 2012-08-10 |
HK1131400A1 (en) | 2010-01-22 |
CA2661748A1 (en) | 2008-03-06 |
DK2061803T4 (da) | 2022-12-05 |
AU2007291283A1 (en) | 2008-03-06 |
PL2061803T3 (pl) | 2020-02-28 |
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