DK200401093A - Konserveret pufret, isotonisk saltholdig kontaktlinseoplösning samt dens anvendelse - Google Patents
Konserveret pufret, isotonisk saltholdig kontaktlinseoplösning samt dens anvendelse Download PDFInfo
- Publication number
- DK200401093A DK200401093A DK200401093A DKPA200401093A DK200401093A DK 200401093 A DK200401093 A DK 200401093A DK 200401093 A DK200401093 A DK 200401093A DK PA200401093 A DKPA200401093 A DK PA200401093A DK 200401093 A DK200401093 A DK 200401093A
- Authority
- DK
- Denmark
- Prior art keywords
- contact lens
- solution
- isotonic saline
- preserved
- lens solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/12—Non-macromolecular oxygen-containing compounds, e.g. hydrogen peroxide or ozone
- A61L12/124—Hydrogen peroxide; Peroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Description
PATENTKRAV 1. Konserveret, pufret, isotonisk, saltholdig kontaktlinseopløsning, som er forenelig med øjets omgivelser og har en pH-værdi på 5,5-8, kendetegnet ved, at opløsningen i det væsentlige består af (i) natriumperborat eller natriumperoxid som en hydrogen- peroxid-kilde, der tilvejebringer hydrogenperoxid i en mænge på 0,001 og derover men mindre end 0,01 (100 ppm) vægt-%, (ii) en hydrogenper oxidstabilisator, som er en phosphon-syre valgt blandt forbindelser med formel (I)
hvori z er et helt tal på 0-3, og forbindelser med formlen (II)
hvor n, m, p og q hver for sig er 0-4, og fysiologisk acceptable salte deraf, (iii) en puffer og (iv) vand, natriumchlorid og eventuelt et yderligere toni-citetsforøgende middel. 2. Opløsning ifølge krav 1, hvor opløsningen har en pH-værdi på 6,5-7,5. 3. Opløsning ifølge krav 1 eller 2, hvor natiumperborat er anvendt som hydrogenperoxid-kilde. 4. Opløsningen ifølge krav 3, hvor en natriumholdig boratforbindelse og borsyre er anvendt som puffer (iii) . 5. Opløsning ifølge ethvert af kravene 1-4, hvor hydrogen-peroxidstabilisatoren er diethylentriaminpenta(methylen-phosphonsyre) eller et fysiologisk acceptabelt salt deraf. 6. Opløsning ifølge ethvert af kravene 1-5 indeholdende fra 0,002 til 0,03% hydrogenperoxidstabilisator. 7. Opløsning ifølge ethvert af kravene 1-4, hvor hydrogen-peroxidstabilisatoren er 1-hydroxyethyliden-l,1-diphos-phonsyre eller et fysiologisk acceptabelt salt deraf, hvor stabilisatoren foreligger i en mængde fra 0,005 til 0,2 vægt-%. S. Anvendelse af en opløsnig ifølge ethvert af kravene 1-7 som en konserveret saltopløsning, som en konserveret kontaktlinsestabiliseringsopløsning eller som en konserveret kontaktlinsebehandlingsopløsning til kontaktlinser under perioder, hvor de ikke bæres.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22916388A | 1988-08-04 | 1988-08-04 | |
| US22916388 | 1988-08-04 | ||
| DK198903816A DK175513B1 (da) | 1988-08-04 | 1989-08-03 | Fremgangsmåde til konservering af ophthalmiske oplösninger samt midler dertil |
| DK381689 | 1989-08-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK200401093A true DK200401093A (da) | 2004-07-09 |
| DK175864B1 DK175864B1 (da) | 2005-04-18 |
Family
ID=22860073
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198903816A DK175513B1 (da) | 1988-08-04 | 1989-08-03 | Fremgangsmåde til konservering af ophthalmiske oplösninger samt midler dertil |
| DK200401093A DK175864B1 (da) | 1988-08-04 | 2004-07-09 | Konserveret pufret, isotonisk saltholdig kontaktlinseoplösning samt dens anvendelse |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198903816A DK175513B1 (da) | 1988-08-04 | 1989-08-03 | Fremgangsmåde til konservering af ophthalmiske oplösninger samt midler dertil |
Country Status (26)
| Country | Link |
|---|---|
| EP (2) | EP0354186B1 (da) |
| JP (1) | JP2915008B2 (da) |
| KR (1) | KR100193585B1 (da) |
| AR (1) | AR243374A1 (da) |
| AT (2) | ATE141803T1 (da) |
| AU (1) | AU628835B2 (da) |
| CA (1) | CA1339031C (da) |
| DE (2) | DE68929516T2 (da) |
| DK (2) | DK175513B1 (da) |
| ES (1) | ES2091204T3 (da) |
| FI (2) | FI98334C (da) |
| GR (1) | GR3020899T3 (da) |
| HK (1) | HK1002991A1 (da) |
| HR (1) | HRP940515A2 (da) |
| IE (2) | IE81140B1 (da) |
| IL (1) | IL91131A (da) |
| IN (1) | IN170160B (da) |
| MX (1) | MX174097B (da) |
| NO (2) | NO177626C (da) |
| NZ (1) | NZ230175A (da) |
| PH (1) | PH27399A (da) |
| PT (1) | PT91349B (da) |
| SG (1) | SG64856A1 (da) |
| SI (1) | SI8911541A (da) |
| YU (1) | YU154189A (da) |
| ZA (1) | ZA895932B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO177481C (no) * | 1991-09-10 | 1995-09-27 | Hydrotec Norge | Fremgangsmåte og anordning til desinfisering av råmaterialer, produkter og produksjonsutstyr |
| GB9122048D0 (en) * | 1991-10-17 | 1991-11-27 | Interox Chemicals Ltd | Compositions and uses thereof |
| US5611464A (en) * | 1995-05-30 | 1997-03-18 | Ciba Geigy Corporation | Container for preserving media in the tip of a solution dispenser |
| US5683993A (en) * | 1995-06-22 | 1997-11-04 | Ciba Vision Corporation | Compositions and methods for stabilizing polymers |
| JPH09206362A (ja) * | 1996-02-05 | 1997-08-12 | Tomey Technol Corp | コンタクトレンズ用消毒洗浄組成物及びそれを用いたコンタクトレンズの消毒洗浄方法 |
| FR2751634B1 (fr) * | 1996-07-29 | 1998-09-11 | Essilor Int | Solution stabilisee et tamponnee de peroxyde d'hydrogene, son procede de fabrication et son utilisation a la decontamination de lentilles de contact |
| GB2323180A (en) * | 1997-01-23 | 1998-09-16 | Waverley Pharma Ltd | Hydrogen peroxide contact lens solution |
| JPH1143446A (ja) * | 1997-05-20 | 1999-02-16 | Senju Pharmaceut Co Ltd | 水性製剤の増粘剤 |
| JP2011042682A (ja) * | 1997-05-20 | 2011-03-03 | Senju Pharmaceut Co Ltd | 水性製剤の増粘剤 |
| JP2004525865A (ja) * | 2000-11-08 | 2004-08-26 | バイオ−コンセプト・ラボラトリーズ | 過酸化物源およびカチオン性ポリマー防腐剤を含有する改良した眼科用およびコンタクトレンズ用溶液 |
| US20070092582A1 (en) * | 2002-01-18 | 2007-04-26 | Fu-Pao Tsao | Methods of preserving ophthalmic solutions and preserved ophthalmic solutions |
| US20070048389A1 (en) * | 2005-08-26 | 2007-03-01 | Fu-Pao Tsao | Stabilized and preserved ketotifen ophthalmic compositions |
| US20070048388A1 (en) * | 2005-08-26 | 2007-03-01 | Fu-Pao Tsao | Stabilized and preserved ketotifen ophthalmic compositions |
| BRPI0709549A2 (pt) * | 2006-03-17 | 2011-07-19 | Johnson & Johnson Vision Care | métodos para estabilizar composições instáveis oxidativamente |
| US9481856B2 (en) | 2008-06-09 | 2016-11-01 | Bausch & Lomb Incorporated | Pharmaceutical formulations comprising stabilized polysaccharides and source of hydrogen peroxide |
| TW201127423A (en) * | 2009-12-17 | 2011-08-16 | Alcon Res Ltd | Ophthalmic solutions with improved disinfection profiles |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1382466A (en) * | 1971-04-30 | 1975-01-29 | Allergan Pharma | Germicide |
| US4304762A (en) * | 1978-09-27 | 1981-12-08 | Lever Brothers Company | Stabilization of hydrogen peroxide |
| ATE63805T1 (de) * | 1986-10-14 | 1991-06-15 | Ciba Geigy Ag | Verfahren zur desinfektion von weichen kontaktlinsen mit einer stabilisierten wasserstoffperoxydloesung. |
| US4812173A (en) * | 1987-05-01 | 1989-03-14 | Ciba-Geigy Corporation | Stabilized hydrogen peroxide contact lens disinfecting solution |
-
1989
- 1989-07-27 ES ES89810578T patent/ES2091204T3/es not_active Expired - Lifetime
- 1989-07-27 DE DE68929516T patent/DE68929516T2/de not_active Expired - Lifetime
- 1989-07-27 AT AT89810578T patent/ATE141803T1/de not_active IP Right Cessation
- 1989-07-27 EP EP89810578A patent/EP0354186B1/en not_active Expired - Lifetime
- 1989-07-27 SG SG1996001088A patent/SG64856A1/en unknown
- 1989-07-27 EP EP95117751A patent/EP0706802B1/en not_active Expired - Lifetime
- 1989-07-27 IL IL91131A patent/IL91131A/xx not_active IP Right Cessation
- 1989-07-27 DE DE68927030T patent/DE68927030T2/de not_active Expired - Lifetime
- 1989-07-27 AT AT95117751T patent/ATE262354T1/de not_active IP Right Cessation
- 1989-07-28 PH PH39017A patent/PH27399A/en unknown
- 1989-07-28 IN IN556/MAS/89A patent/IN170160B/en unknown
- 1989-08-02 AR AR89314571A patent/AR243374A1/es active
- 1989-08-02 NZ NZ230175A patent/NZ230175A/xx unknown
- 1989-08-02 JP JP1199504A patent/JP2915008B2/ja not_active Expired - Lifetime
- 1989-08-02 FI FI893661A patent/FI98334C/fi active IP Right Grant
- 1989-08-02 CA CA000607281A patent/CA1339031C/en not_active Expired - Lifetime
- 1989-08-02 PT PT91349A patent/PT91349B/pt not_active IP Right Cessation
- 1989-08-02 MX MX017043A patent/MX174097B/es unknown
- 1989-08-03 IE IE251789A patent/IE81140B1/en not_active IP Right Cessation
- 1989-08-03 AU AU39303/89A patent/AU628835B2/en not_active Expired
- 1989-08-03 ZA ZA895932A patent/ZA895932B/xx unknown
- 1989-08-03 DK DK198903816A patent/DK175513B1/da not_active IP Right Cessation
- 1989-08-03 YU YU01541/89A patent/YU154189A/xx unknown
- 1989-08-03 NO NO893142A patent/NO177626C/no not_active IP Right Cessation
- 1989-08-03 IE IE960417A patent/IE960417L/xx not_active IP Right Cessation
- 1989-08-03 SI SI8911541A patent/SI8911541A/sl unknown
- 1989-08-04 KR KR1019890011137A patent/KR100193585B1/ko not_active IP Right Cessation
-
1994
- 1994-09-08 HR HR940515A patent/HRP940515A2/xx not_active Application Discontinuation
-
1995
- 1995-01-20 NO NO950227A patent/NO307500B1/no not_active IP Right Cessation
-
1996
- 1996-03-22 FI FI961336A patent/FI106363B/fi active
- 1996-08-29 GR GR960402053T patent/GR3020899T3/el unknown
-
1998
- 1998-03-12 HK HK98102059A patent/HK1002991A1/xx not_active IP Right Cessation
-
2004
- 2004-07-09 DK DK200401093A patent/DK175864B1/da not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |