DK1861405T3 - Fremgangsmåde til reduktion af alfa,beta-umættede ketoner i opioidsammensætninger - Google Patents

Fremgangsmåde til reduktion af alfa,beta-umættede ketoner i opioidsammensætninger

Info

Publication number
DK1861405T3
DK1861405T3 DK06707309T DK06707309T DK1861405T3 DK 1861405 T3 DK1861405 T3 DK 1861405T3 DK 06707309 T DK06707309 T DK 06707309T DK 06707309 T DK06707309 T DK 06707309T DK 1861405 T3 DK1861405 T3 DK 1861405T3
Authority
DK
Denmark
Prior art keywords
beta
unsaturated ketones
reducing alpha
opioid compositions
reducing
Prior art date
Application number
DK06707309T
Other languages
English (en)
Inventor
Robert J Kupper
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of DK1861405T3 publication Critical patent/DK1861405T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK06707309T 2005-03-04 2006-02-27 Fremgangsmåde til reduktion af alfa,beta-umættede ketoner i opioidsammensætninger DK1861405T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65879105P 2005-03-04 2005-03-04
PCT/EP2006/001798 WO2006094672A1 (en) 2005-03-04 2006-02-27 Method of reducing alpha, beta unsaturated ketones in opioid compositions

Publications (1)

Publication Number Publication Date
DK1861405T3 true DK1861405T3 (da) 2009-07-20

Family

ID=36301669

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06707309T DK1861405T3 (da) 2005-03-04 2006-02-27 Fremgangsmåde til reduktion af alfa,beta-umættede ketoner i opioidsammensætninger
DK09158939.0T DK2112153T3 (da) 2005-03-04 2006-02-27 Fremgangsmåde til reduktion af alpha, beta-umættede ketoner i opioidsammensætninger

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09158939.0T DK2112153T3 (da) 2005-03-04 2006-02-27 Fremgangsmåde til reduktion af alpha, beta-umættede ketoner i opioidsammensætninger

Country Status (19)

Country Link
US (1) US7939543B2 (da)
EP (2) EP1861405B1 (da)
JP (1) JP5314894B2 (da)
KR (1) KR100941761B1 (da)
CN (1) CN101133062B (da)
AT (2) ATE430153T1 (da)
CA (1) CA2598774C (da)
CY (2) CY1109262T1 (da)
DE (2) DE602006006558D1 (da)
DK (2) DK1861405T3 (da)
ES (2) ES2355870T3 (da)
HK (2) HK1111695A1 (da)
HR (2) HRP20090387T1 (da)
ME (2) ME01594B (da)
PL (2) PL1861405T3 (da)
PT (2) PT2112153E (da)
RS (2) RS51568B (da)
SI (2) SI2112153T1 (da)
WO (1) WO2006094672A1 (da)

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DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
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BRPI0912014A2 (pt) 2008-05-09 2019-03-06 Grünenthal GmbH processo para a preparação de uma formulação em pó intermediária e uma forma de dosagem sólida final sob uso de uma etapa de congelamento por atomização
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TW201105316A (en) * 2009-07-22 2011-02-16 Gruenenthal Gmbh Hot-melt extruded pharmaceutical dosage form
BR112012004525A2 (pt) * 2009-08-31 2016-03-22 Depomed Inc composição farmacêuticas gástrico-rententivas para liberação imediata ou prolongada de acetaminofeno
US8597681B2 (en) 2009-12-22 2013-12-03 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
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TWI478928B (zh) 2010-06-11 2015-04-01 Rhodes Technologies 用於製備ｎ－烯丙基化合物之過渡金屬催化的製程及其用途
AU2011263416B2 (en) 2010-06-11 2014-04-10 Rhodes Technologies Process for N-dealkylation of tertiary amines
PE20131102A1 (es) 2010-09-02 2013-10-12 Gruenenthal Chemie Forma de dosificacion resistente a manipulacion que comprende una sal inorganica
CN103179954A (zh) 2010-09-02 2013-06-26 格吕伦塔尔有限公司 包含阴离子聚合物的抗破碎剂型
US8858963B1 (en) 2011-05-17 2014-10-14 Mallinckrodt Llc Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
US9050335B1 (en) 2011-05-17 2015-06-09 Mallinckrodt Llc Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia
US8741885B1 (en) 2011-05-17 2014-06-03 Mallinckrodt Llc Gastric retentive extended release pharmaceutical compositions
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Also Published As

Publication number Publication date
HRP20090387T1 (en) 2009-08-31
SI1861405T1 (sl) 2009-10-31
CA2598774A1 (en) 2006-09-14
US20080132702A1 (en) 2008-06-05
PT2112153E (pt) 2010-12-17
RS51131B (sr) 2010-10-31
CA2598774C (en) 2010-12-21
EP1861405A1 (en) 2007-12-05
EP2112153B1 (en) 2010-11-10
ATE430153T1 (de) 2009-05-15
HRP20110078T1 (hr) 2011-03-31
KR20070108931A (ko) 2007-11-13
CN101133062B (zh) 2014-08-06
KR100941761B1 (ko) 2010-02-11
PL1861405T3 (pl) 2009-10-30
DE602006006558D1 (de) 2009-06-10
US7939543B2 (en) 2011-05-10
WO2006094672A1 (en) 2006-09-14
JP2008531626A (ja) 2008-08-14
ATE487722T1 (de) 2010-11-15
DE602006018208D1 (de) 2010-12-23
DK2112153T3 (da) 2011-02-14
JP5314894B2 (ja) 2013-10-16
EP2112153A1 (en) 2009-10-28
ES2326491T3 (es) 2009-10-13
EP1861405B1 (en) 2009-04-29
ME01594B (me) 2014-09-20
CN101133062A (zh) 2008-02-27
PL2112153T3 (pl) 2011-04-29
ES2355870T3 (es) 2011-03-31
HK1135107A1 (en) 2010-05-28
SI2112153T1 (sl) 2011-02-28
CY1109262T1 (el) 2014-07-02
CY1111241T1 (el) 2015-06-11
ME01184B (me) 2013-03-20
RS51568B (en) 2011-08-31
PT1861405E (pt) 2009-07-27
HK1111695A1 (en) 2008-08-15

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