DK176209B1 - Cyclosporinformulering - Google Patents
Cyclosporinformulering Download PDFInfo
- Publication number
- DK176209B1 DK176209B1 DK199000327A DK32790A DK176209B1 DK 176209 B1 DK176209 B1 DK 176209B1 DK 199000327 A DK199000327 A DK 199000327A DK 32790 A DK32790 A DK 32790A DK 176209 B1 DK176209 B1 DK 176209B1
- Authority
- DK
- Denmark
- Prior art keywords
- component
- approx
- components
- compositions
- ciclosporin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8902901 | 1989-02-09 | ||
GB898902898A GB8902898D0 (en) | 1989-02-09 | 1989-02-09 | Improvements in or relating to organic compounds |
GB8902898 | 1989-02-09 | ||
GB898902901A GB8902901D0 (en) | 1989-02-09 | 1989-02-09 | Improvements in or relating to organic compounds |
GB898903147A GB8903147D0 (en) | 1989-02-13 | 1989-02-13 | Improvements in or relating to organic compounds |
GB8903147 | 1989-02-13 | ||
GB898903663A GB8903663D0 (en) | 1989-02-17 | 1989-02-17 | Improvements in or relating to organic compounds |
GB8903663 | 1989-02-17 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK32790D0 DK32790D0 (da) | 1990-02-07 |
DK32790A DK32790A (da) | 1990-08-10 |
DK176209B1 true DK176209B1 (da) | 2007-02-05 |
Family
ID=27450262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK199000327A DK176209B1 (da) | 1989-02-09 | 1990-02-07 | Cyclosporinformulering |
Country Status (25)
Country | Link |
---|---|
JP (3) | JP3484190B2 (fr) |
KR (1) | KR0170769B1 (fr) |
AT (1) | AT404552B (fr) |
AU (1) | AU630413B2 (fr) |
BE (1) | BE1003009A5 (fr) |
CA (1) | CA2009533C (fr) |
CH (1) | CH679277A5 (fr) |
CY (1) | CY1903A (fr) |
DE (1) | DE4003844B4 (fr) |
DK (1) | DK176209B1 (fr) |
ES (1) | ES2021942A6 (fr) |
FI (1) | FI97524C (fr) |
FR (1) | FR2642650B1 (fr) |
GB (1) | GB2230440B (fr) |
HK (1) | HK37296A (fr) |
HU (1) | HU213394B (fr) |
IT (1) | IT1240758B (fr) |
LU (1) | LU87675A1 (fr) |
MY (1) | MY107377A (fr) |
NL (1) | NL195028C (fr) |
NO (1) | NO301576B1 (fr) |
NZ (1) | NZ232401A (fr) |
PH (1) | PH30917A (fr) |
PT (1) | PT93079B (fr) |
SE (1) | SE511398C2 (fr) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2222770B (en) * | 1988-09-16 | 1992-07-29 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporins |
HU208491B (en) * | 1990-11-27 | 1993-11-29 | Gyogyszerkutato Intezet | Process for producing oral pharmaceutical composition containing cyclosporin |
MX9201782A (es) † | 1991-04-19 | 1992-10-01 | Sandoz Ag | Particulas de sustancias biologicamente activas, sustancialmente insolubles en agua, proceso para su produccion y composicion farmaceutica que las contiene. |
GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
US6262022B1 (en) | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
SG45449A1 (en) | 1992-05-13 | 1998-01-16 | Sandoz Ltd | Ophthalmic compositions |
US5759566A (en) * | 1992-07-28 | 1998-06-02 | Poli Industria Chimica Spa | Microemulsion pharmaceutical compositions for the delivery of pharmaceutically active agents |
DK0589843T3 (da) | 1992-09-25 | 2002-04-02 | Novartis Ag | Cyclosporinholdige farmaceutiske præparater |
WO1994023733A1 (fr) * | 1993-04-20 | 1994-10-27 | Dr. Rentschler Arzneimittel Gmbh & Co. | Nouvelles compositions pharmaceutiques pour administration orale contenant de la cyclosporine |
DE4412201A1 (de) * | 1993-04-20 | 1994-11-10 | Rentschler Arzneimittel | Neue pharmazeutische Zubereitungen zur oralen Verabreichung enthaltend Cyclosporin |
DE4340781C3 (de) * | 1993-11-30 | 2000-01-27 | Novartis Ag | Cyclosporin enthaltende flüssige Zubereitungen und Verfahren zu ihrer Herstellung |
KR0146671B1 (ko) * | 1994-02-25 | 1998-08-17 | 김충환 | 사이클로스포린-함유 분말 조성물 |
DE59510233D1 (de) | 1994-11-03 | 2002-07-11 | Novartis Ag | Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung |
US5679566A (en) * | 1995-01-20 | 1997-10-21 | University Of Massachusetts Medical Center | Yeast NMD2 gene |
US5766629A (en) | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
US5827822A (en) * | 1996-03-25 | 1998-10-27 | Sangstat Medical Corporation | Cyclosporin a formulations as nanoparticles |
US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
DE19549852B4 (de) | 1995-11-29 | 2009-06-04 | Novartis Ag | Cyclosporin enthaltende Präparate |
US5798333A (en) * | 1996-09-17 | 1998-08-25 | Sherman; Bernard C. | Water-soluble concentrates containing cyclosporins |
AU762247B2 (en) * | 1997-01-30 | 2003-06-19 | Novartis Ag | Oil-free pharmaceutical compositions containing cyclosporin A |
EP0988046B1 (fr) * | 1997-01-30 | 2004-09-15 | Novartis AG | Compositions pharmaceutiques exemptes d'huile, a base de cyclosporine a |
SI0969856T1 (en) * | 1997-03-12 | 2005-06-30 | Abbott Laboratories | Hydrophilic binary systems for the administration of cyclosporine |
NZ328751A (en) * | 1997-09-16 | 1999-01-28 | Bernard Charles Sherman | Solid medicament containing an anionic surfactant and cyclosporin |
US6447806B1 (en) | 1999-02-25 | 2002-09-10 | Novartis Ag | Pharmaceutical compositions comprised of stabilized peptide particles |
US6979672B2 (en) | 2002-12-20 | 2005-12-27 | Polichem, S.A. | Cyclosporin-based pharmaceutical compositions |
JP4521554B2 (ja) * | 2004-03-31 | 2010-08-11 | マイラン製薬株式会社 | シクロスポリン製剤 |
CN101360485B (zh) * | 2005-10-26 | 2013-04-17 | 班纳制药公司 | 作为胶囊填充物的基于亲水性载体的双重控释基质系统 |
KR20160033796A (ko) | 2006-03-28 | 2016-03-28 | 자블린 파머슈티칼스 인코포레이티드 | 저 복용량의 디클로페낙 및 베타-사이클로덱스트린 제형 |
US7495024B2 (en) | 2006-08-07 | 2009-02-24 | Via Pharmaceuticals, Inc. | Phenylalkyl N-hydroxyureas for combating atherosclerotic plaque |
DE102008059201A1 (de) | 2008-11-27 | 2010-06-02 | GÖPFERICH, Achim, Prof. Dr. | In situ präzipitierende Arzneistofflösungen |
KR102146704B1 (ko) | 2018-04-13 | 2020-08-21 | 가천대학교 산학협력단 | 사이클로스포린 A (CsA) 경피 및 피내 약물전달용 마이크로구조체 |
EP4166133A1 (fr) * | 2021-10-13 | 2023-04-19 | Chugai Seiyaku Kabushiki Kaisha | Composition contenant un composé peptidique et un tensioactif |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2907460A1 (de) * | 1978-03-07 | 1979-09-13 | Sandoz Ag | Neue resorbierbare galenische kompositionen |
JPS61280435A (ja) * | 1985-04-04 | 1986-12-11 | Kanji Takada | サイクロスポリン類のリンパ指向性製剤 |
NL8600050A (nl) * | 1986-01-13 | 1987-08-03 | Sanico Nv | Farmaceutisch preparaat met vertraagde afgifte van het werkzame bestanddeel en werkwijze voor de bereiding er van. |
GB8602372D0 (en) * | 1986-01-31 | 1986-03-05 | Sandoz Ltd | Organic compounds |
CA1290249C (fr) * | 1986-04-09 | 1991-10-08 | Cetus Corporation | TRAITEMENT A BASE D'INTERLEUKINE-2 ET (OU) D'INTERFERON .beta. ET FACTEUR DE NECROSE TUMORALE |
CA1341374C (fr) * | 1986-11-13 | 2002-07-09 | Alan N. Houghton | Compositions et procede de traitement du cancer utilisant un anticorps monoclonal dirige contre le ganglioside gd3, ensemble avec il-2 |
EP0296122B1 (fr) * | 1987-06-17 | 1993-09-29 | Sandoz Ag | Cycloporines et leur emploi comme médicaments |
JP2536876B2 (ja) * | 1987-07-31 | 1996-09-25 | 寛治 高田 | シクロスポリンの溶解性粉末状製剤 |
DE3830494B4 (de) * | 1987-09-15 | 2006-05-18 | Novartis Ag | Wasserlösliche Monoester als Solubilisatoren für pharmakologische Wirkstoffe und pharmazeutische Hilfsstoffe |
US5756450A (en) * | 1987-09-15 | 1998-05-26 | Novartis Corporation | Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms |
HU205010B (en) * | 1987-09-15 | 1992-03-30 | Sandoz Ag | Process for producing pharmaceutical compositions comprising compounds soluble up to 1 per cent and having medical activity |
JP2792862B2 (ja) * | 1988-07-30 | 1998-09-03 | 寛治 高田 | 経口腸溶製剤 |
GB2222770B (en) * | 1988-09-16 | 1992-07-29 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporins |
JPH1038029A (ja) * | 1996-07-26 | 1998-02-13 | Ebara Corp | 制振機能付き円板状構造物 |
JPH10280435A (ja) * | 1997-04-03 | 1998-10-20 | Sekisui Chem Co Ltd | 地下室の構築方法 |
-
1990
- 1990-02-05 BE BE9000133A patent/BE1003009A5/fr not_active IP Right Cessation
- 1990-02-05 CH CH359/90A patent/CH679277A5/de not_active IP Right Cessation
- 1990-02-05 FR FR9001389A patent/FR2642650B1/fr not_active Expired - Lifetime
- 1990-02-05 GB GB9002504A patent/GB2230440B/en not_active Expired - Lifetime
- 1990-02-07 FI FI900604A patent/FI97524C/fi active IP Right Grant
- 1990-02-07 MY MYPI90000191A patent/MY107377A/en unknown
- 1990-02-07 PH PH40014A patent/PH30917A/en unknown
- 1990-02-07 HU HU90701A patent/HU213394B/hu unknown
- 1990-02-07 NZ NZ232401A patent/NZ232401A/en unknown
- 1990-02-07 LU LU87675A patent/LU87675A1/fr unknown
- 1990-02-07 DK DK199000327A patent/DK176209B1/da not_active IP Right Cessation
- 1990-02-07 PT PT93079A patent/PT93079B/pt not_active IP Right Cessation
- 1990-02-07 CA CA002009533A patent/CA2009533C/fr not_active Expired - Lifetime
- 1990-02-07 SE SE9000441A patent/SE511398C2/sv not_active Application Discontinuation
- 1990-02-07 NO NO900577A patent/NO301576B1/no not_active IP Right Cessation
- 1990-02-08 IT IT47609A patent/IT1240758B/it active IP Right Grant
- 1990-02-08 JP JP03134890A patent/JP3484190B2/ja not_active Expired - Lifetime
- 1990-02-08 AU AU49252/90A patent/AU630413B2/en not_active Expired
- 1990-02-08 NL NL9000299A patent/NL195028C/nl not_active IP Right Cessation
- 1990-02-08 AT AT0027290A patent/AT404552B/de not_active IP Right Cessation
- 1990-02-08 KR KR1019900001492A patent/KR0170769B1/ko not_active IP Right Cessation
- 1990-02-08 DE DE4003844A patent/DE4003844B4/de not_active Expired - Lifetime
- 1990-02-09 ES ES9000397A patent/ES2021942A6/es not_active Expired - Lifetime
-
1996
- 1996-03-07 HK HK37296A patent/HK37296A/xx not_active IP Right Cessation
- 1996-11-22 CY CY190396A patent/CY1903A/xx unknown
-
2001
- 2001-04-25 JP JP2001127538A patent/JP4073641B2/ja not_active Expired - Lifetime
-
2005
- 2005-09-13 JP JP2005265724A patent/JP2006001947A/ja active Pending
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |