DK175429B1 - Fremgangsmåde til immunbestemmelse med reduceret uspecifikke forstyrrelser og diagnostisk middel til anvendelse ved fremgangsmåden - Google Patents

Fremgangsmåde til immunbestemmelse med reduceret uspecifikke forstyrrelser og diagnostisk middel til anvendelse ved fremgangsmåden Download PDF

Info

Publication number
DK175429B1
DK175429B1 DK198900966A DK96689A DK175429B1 DK 175429 B1 DK175429 B1 DK 175429B1 DK 198900966 A DK198900966 A DK 198900966A DK 96689 A DK96689 A DK 96689A DK 175429 B1 DK175429 B1 DK 175429B1
Authority
DK
Denmark
Prior art keywords
igg
specific
aggregates
reactants
mak33
Prior art date
Application number
DK198900966A
Other languages
Danish (da)
English (en)
Other versions
DK96689A (da
DK96689D0 (da
Inventor
Helmut Lenz
Ellen Moessner
Werner Stock
Norbert Franken
Albert Roeder
Harald Haug
Robert Crance Mccarthy
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of DK96689D0 publication Critical patent/DK96689D0/da
Publication of DK96689A publication Critical patent/DK96689A/da
Application granted granted Critical
Publication of DK175429B1 publication Critical patent/DK175429B1/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Steroid Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicinal Preparation (AREA)
DK198900966A 1988-03-03 1989-02-28 Fremgangsmåde til immunbestemmelse med reduceret uspecifikke forstyrrelser og diagnostisk middel til anvendelse ved fremgangsmåden DK175429B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16405488 1988-03-03
US07/164,054 US4914040A (en) 1988-03-03 1988-03-03 Reagent and method for determination of a polyvalent substance using an immunoaggregate

Publications (3)

Publication Number Publication Date
DK96689D0 DK96689D0 (da) 1989-02-28
DK96689A DK96689A (da) 1989-09-04
DK175429B1 true DK175429B1 (da) 2004-10-18

Family

ID=22592781

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900966A DK175429B1 (da) 1988-03-03 1989-02-28 Fremgangsmåde til immunbestemmelse med reduceret uspecifikke forstyrrelser og diagnostisk middel til anvendelse ved fremgangsmåden

Country Status (18)

Country Link
US (1) US4914040A (fi)
EP (1) EP0331068B1 (fi)
JP (1) JPH0823560B2 (fi)
AT (1) ATE82072T1 (fi)
AU (1) AU616484B2 (fi)
CA (1) CA1340572C (fi)
DD (1) DD280396A5 (fi)
DE (2) DE3905505A1 (fi)
DK (1) DK175429B1 (fi)
ES (1) ES2045216T3 (fi)
FI (1) FI92879C (fi)
GR (1) GR3006991T3 (fi)
HU (1) HU212322B (fi)
IE (1) IE62974B1 (fi)
LV (1) LV10538B (fi)
PT (1) PT89889B (fi)
RU (1) RU2032906C1 (fi)
ZA (1) ZA891568B (fi)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3730059A1 (de) * 1987-09-08 1989-03-30 Behringwerke Ag Verfahren zur bestimmung von "loeslichem" fibrin
US5141853A (en) * 1988-07-22 1992-08-25 Abbott Laboratories Determination of ammonia levels in a sample
DE3829245A1 (de) * 1988-08-29 1990-03-01 Boehringer Mannheim Gmbh Verfahren zur bestimmung einer spezifisch bindefaehigen substanz
AU6710790A (en) * 1989-10-24 1991-05-31 E.I. Du Pont De Nemours And Company Use of polymerized immunoglobulin to reduce the incidence of false-positive responses in immunoassays
DE4020204A1 (de) * 1990-06-25 1992-01-02 Boehringer Mannheim Gmbh Durchfuehrung eines homogenen immunoassays nach dem agglutinationsprinzip
US6274325B1 (en) 1990-06-25 2001-08-14 Boehringer Mannheim Gmbh Method for carrying out a homogeneous-immunoassay based on agglutination
JPH04350559A (ja) * 1991-05-28 1992-12-04 Dai Ichi Pure Chem Co Ltd 特異抗体の測定法
WO1993003366A1 (en) * 1991-07-26 1993-02-18 E.I. Du Pont De Nemours And Company Method for eliminating erroneous results in an immunoassay
US5460944A (en) * 1991-10-28 1995-10-24 Boehringer Mannheim Gmbh Storable protein solution
DE4202923A1 (de) * 1992-02-01 1993-08-05 Behringwerke Ag Verfahren zur bestimmung von antigenen oder antikoerpern in gegenwart eines immunkomplexes
IL102495A (en) * 1992-07-14 1998-06-15 Patchornik Avraham Universal standard reagents, method of preparing same and use thereof
IL106887A (en) * 1993-09-02 1997-02-18 Yissum Res Dev Co Pharmaceutical and diagnostic compositions and a method for drug targeting
GB9403215D0 (en) * 1994-02-19 1994-04-13 Kodak Ltd Chemical modification of antibodies and antigens
WO1995023801A1 (de) * 1994-03-05 1995-09-08 Boehringer Mannheim Gmbh Entstörmittel zum einsatz bei immunoassays
DE4407423A1 (de) * 1994-03-05 1995-09-07 Boehringer Mannheim Gmbh Entstörmittel zum Einsatz bei Immunoassays
DE4439452A1 (de) * 1994-11-04 1996-05-09 Boehringer Mannheim Gmbh Antikörperklassenspezifisches Entstörungsreagenz
DE19621133A1 (de) * 1996-05-24 1997-11-27 Boehringer Mannheim Gmbh Bestimmungsverfahren mit oligomerisierten Rezeptoren
DE19731465A1 (de) * 1997-07-22 1999-01-28 Boehringer Mannheim Gmbh Verwendung von Kontrollflächen zur Detektion von Störproben in einem Nachweisverfahren
ES2185104T3 (es) * 1997-12-11 2003-04-16 Roche Diagnostics Gmbh Eliminacionde las interferencias en procedimientos de diagnostico mediante peptidos de d-aminoacidos.
DE19828466A1 (de) * 1998-06-26 1999-12-30 Roche Diagnostics Gmbh Entstörung von Immunoassays durch Substanzen, die aus den Framework-Regionen von Antikörpern abgeleitet sind
US6406858B1 (en) * 1998-11-27 2002-06-18 Bayer Corporation System for the reduction of interferences in immunoassays
CA2422856C (en) * 2000-09-25 2012-02-07 Abbott Laboratories Methods and kits for decreasing interferences of assay samples containing plasma or serum in specific binding assays by using a large polycation
DE10059720A1 (de) 2000-11-30 2002-06-06 Roche Diagnostics Gmbh Verwendung intramolekular kovalent vernetzter Proteine als Bindepartner in Immunoassays
DE10064827A1 (de) 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
US20040091952A1 (en) * 2002-07-25 2004-05-13 Sysmex Corporation Reagent kit for detecting lupus anticoagulant
US20040018556A1 (en) * 2002-07-29 2004-01-29 Cantor Thomas L. Reagent and method for determination of a substance using an immunoaggregator
EP1469317B1 (en) * 2003-03-28 2008-10-08 Sysmex Corporation Reagent for detecting anti-phospholipid antibody
JP2007526993A (ja) * 2003-07-08 2007-09-20 インバーネス・メデイカル・スウイツツアーランド・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 粒子凝集検出方法および装置
US20050112586A1 (en) * 2003-11-24 2005-05-26 Roland Janzen Method and composition for stabilizing liquid reagents
DE602005006633D1 (de) * 2004-02-06 2008-06-26 Sysmex Corp Reagenziensatz zum Nachweis von Lupus-Antikoagulant.
CN1969189B (zh) * 2004-06-14 2012-03-21 协和梅迪克斯株式会社 非特异性反应被抑制的可溶性白介素-2受体免疫学测定方法和试剂
US20060105402A1 (en) * 2004-11-15 2006-05-18 Gennady Rott Blood type method system and device
US7172906B2 (en) * 2004-11-16 2007-02-06 Dade Behring Inc. Reduction of non-specific binding in assays
US20110189704A1 (en) * 2007-08-23 2011-08-04 Mitsubishi Chemical Medience Corporation Non-specific reaction inhibitor
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
WO2019207115A1 (en) * 2018-04-26 2019-10-31 Statens Serum Institut Improved immunoassays
CN109342743B (zh) * 2018-12-05 2022-02-18 菲鹏生物股份有限公司 一种能够与类风湿因子高效结合的变性IgG的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0083869B1 (en) * 1982-01-05 1985-10-16 International Institute Of Cellular And Molecular Pathology (Icp) Method of immunoassay
DE3206729A1 (de) * 1982-02-25 1983-09-01 Behringwerke Ag, 3550 Marburg Immunologisches agglutinationsverfahren
DE3225027A1 (de) * 1982-07-05 1984-01-05 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemisches messverfahren
US4659678A (en) * 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
US4474892A (en) * 1983-02-16 1984-10-02 Board Of Trustees Of The Leland Stanford Junior University Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same
US4582810A (en) * 1983-09-30 1986-04-15 Becton, Dickinson And Company Immuno-agglutination particle suspensions
JPS60256057A (ja) * 1984-06-01 1985-12-17 Dai Ichi Pure Chem Co Ltd 免疫学的測定法
JPS6165162A (ja) * 1984-09-05 1986-04-03 Chemo Sero Therapeut Res Inst モノクロ−ナル抗体を用いた免疫学的測定方法における非特異反応吸収剤
JPH0799372B2 (ja) * 1985-07-13 1995-10-25 富士レビオ株式会社 逆受身凝集反応用非特異反応吸収剤

Also Published As

Publication number Publication date
DE3905505A1 (de) 1989-09-14
ES2045216T3 (es) 1994-01-16
AU3090889A (en) 1989-09-07
DE58902586D1 (de) 1992-12-10
US4914040A (en) 1990-04-03
PT89889A (pt) 1989-11-10
FI891012A0 (fi) 1989-03-02
JPH01254869A (ja) 1989-10-11
FI92879C (fi) 1995-01-10
LV10538B (en) 1995-12-20
HUT50988A (en) 1990-03-28
IE890683L (en) 1989-09-03
EP0331068B1 (de) 1992-11-04
ZA891568B (en) 1989-11-29
PT89889B (pt) 1994-05-31
RU2032906C1 (ru) 1995-04-10
GR3006991T3 (fi) 1993-06-30
IE62974B1 (en) 1995-03-08
ATE82072T1 (de) 1992-11-15
DK96689A (da) 1989-09-04
AU616484B2 (en) 1991-10-31
HU212322B (en) 1996-05-28
FI92879B (fi) 1994-09-30
DD280396A5 (de) 1990-07-04
CA1340572C (en) 1999-06-01
JPH0823560B2 (ja) 1996-03-06
FI891012A (fi) 1989-09-04
DK96689D0 (da) 1989-02-28
EP0331068A1 (de) 1989-09-06
LV10538A (lv) 1995-02-20

Similar Documents

Publication Publication Date Title
DK175429B1 (da) Fremgangsmåde til immunbestemmelse med reduceret uspecifikke forstyrrelser og diagnostisk middel til anvendelse ved fremgangsmåden
Wisdom Enzyme-immunoassay.
Yorde et al. Competitive enzyme-liked immunoassay with use of soluble enzyme/antibody immune complexes for labeling. I. Measurement of human choriogonadotropin.
Scharpe et al. Quantitative enzyme immunoassay: current status.
Yolken Enzyme-linked immunosorbent assay (ELISA): a practical tool for rapid diagnosis of viruses and other infectious agents.
US4650751A (en) Protected binding assay avoiding non-specific protein interference
EP0440044A1 (en) Avoidance of human anti-mouse antibody interference in in vitro diagnostic testing
EP0223843A4 (en) METHOD AND ELEMENT FOR DETECTION OF IMMUNE COMPOUNDS.
US20020187510A1 (en) Method for assay of antibodies and antibody assay device
AU5317886A (en) Solid phase diffusion assay
Tuson et al. A novel immunohistochemical technique for demonstration of specific binding of human monoclonal antibodies to human cryostat tissue sections.
Antes et al. Enzyme-linked immunosorbent assay for C1q in human serum by use of monoclonal antibodies
EP0324969A2 (en) Method of measuring transferrin
Marsden et al. Purification of mouse haptoglobin by antibody affinity chromatography and development of an ELISA to measure serum haptoglobin levels
KR910004228B1 (ko) 면역집합물을 사용한 다가성분의 측정방법
Lown et al. Evaluation of an enzyme-linked antiglobulin test for the detection of red cell antibodies
Stefaniak Detection of the Haemophilus somnus antibodies in the bulls’ reproductive tract fluids using the ELISA I. Elaboration of the ELISA for the detection of the specific antibodies in the IgG, IgM and IgA classes
Russell et al. Detection of food antigen-specific IgA immune complexes in human sera
JPS60108756A (ja) 酵素を用いた抗原決定基具有物質の測定方法
Harats et al. IgG rheumatoid factor in purified IgG fractions and whole sera from patients with rheumatoid arthritis
WO1986007152A1 (en) Method and article for detection of immune complexes
AU2004201897B2 (en) Methods for assaying antibody and device for assaying antibody
Nordfang et al. Immunoprecipitates used as a reagent for rheumatoid factors
Lucas et al. The measurement of staphylococcal protein A by ELISA in immunoglobulin preparations
MATSUMOTO THE NUCLEAR STAINING PATTERNS OF ANTINUCLEAR FACTORS OBSERVED WITH IMMUNOENZYME ANTIBODY TECHNIQUE

Legal Events

Date Code Title Description
PUP Patent expired