DK175194B1 - Rekombinante DNA-molekyler, interferon-omega-type gener, transformerede værter indeholdende DNA-informationen, ekspressionsplasmider for interferon-omega-typer, E. coli transformeret hermed, humane interferoner af type I, fremgangsmåde....... - Google Patents

Rekombinante DNA-molekyler, interferon-omega-type gener, transformerede værter indeholdende DNA-informationen, ekspressionsplasmider for interferon-omega-typer, E. coli transformeret hermed, humane interferoner af type I, fremgangsmåde....... Download PDF

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Publication number
DK175194B1
DK175194B1 DK198503463A DK346385A DK175194B1 DK 175194 B1 DK175194 B1 DK 175194B1 DK 198503463 A DK198503463 A DK 198503463A DK 346385 A DK346385 A DK 346385A DK 175194 B1 DK175194 B1 DK 175194B1
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DK198503463A
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English (en)
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DK346385A (da
DK346385D0 (da
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Norbert Hauel
Rudolf Hauptmann
Peter Swetly
Eva Dworkin-Rastl
Guenther Adolf
Peter Meindl
Pieler Christian
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Boehringer Ingelheim Int
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Priority claimed from DE3428370A external-priority patent/DE3428370A1/de
Priority claimed from DE19853505060 external-priority patent/DE3505060A1/de
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of DK346385D0 publication Critical patent/DK346385D0/da
Publication of DK346385A publication Critical patent/DK346385A/da
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Electrotherapy Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK198503463A 1984-08-01 1985-07-30 Rekombinante DNA-molekyler, interferon-omega-type gener, transformerede værter indeholdende DNA-informationen, ekspressionsplasmider for interferon-omega-typer, E. coli transformeret hermed, humane interferoner af type I, fremgangsmåde....... DK175194B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3428370A DE3428370A1 (de) 1984-08-01 1984-08-01 Interferon, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen
DE3428370 1984-08-01
DE19853505060 DE3505060A1 (de) 1985-02-14 1985-02-14 Neue interferone vom typ i, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen
DE3505060 1985-02-14

Publications (3)

Publication Number Publication Date
DK346385D0 DK346385D0 (da) 1985-07-30
DK346385A DK346385A (da) 1986-02-02
DK175194B1 true DK175194B1 (da) 2004-07-05

Family

ID=25823496

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198503463A DK175194B1 (da) 1984-08-01 1985-07-30 Rekombinante DNA-molekyler, interferon-omega-type gener, transformerede værter indeholdende DNA-informationen, ekspressionsplasmider for interferon-omega-typer, E. coli transformeret hermed, humane interferoner af type I, fremgangsmåde.......

Country Status (21)

Country Link
EP (1) EP0170204B1 (fi)
JP (2) JP2566909B2 (fi)
KR (1) KR0136799B1 (fi)
AT (1) ATE67786T1 (fi)
AU (1) AU600653B2 (fi)
BG (1) BG60445B2 (fi)
CA (1) CA1340184C (fi)
DD (1) DD246318A5 (fi)
DE (1) DE3584198D1 (fi)
DK (1) DK175194B1 (fi)
ES (2) ES8609475A1 (fi)
FI (1) FI90667C (fi)
GR (1) GR851866B (fi)
HK (1) HK187896A (fi)
HU (1) HU205779B (fi)
IE (1) IE58942B1 (fi)
IL (1) IL75963A (fi)
MX (1) MX9203645A (fi)
NO (1) NO177863C (fi)
NZ (1) NZ212937A (fi)
PT (1) PT80901B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231176A (en) * 1984-08-27 1993-07-27 Genentech, Inc. Distinct family DNA encoding of human leukocyte interferons
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
EP0490233A1 (de) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung
US4863727A (en) * 1986-04-09 1989-09-05 Cetus Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3633323A1 (de) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega
DE3635867A1 (de) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung
EP1987845B1 (en) 1997-11-20 2012-03-21 Vical Incorporated Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor.
WO2000040273A2 (en) * 1999-01-08 2000-07-13 Vical Incorporated Treatment of viral diseases using an interferon omega expressing polynucleotide
WO2004099231A2 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
KR20090110951A (ko) 2002-03-07 2009-10-23 아이드게노쉬쉐 테흐니쉐 호흐슐레 쥬리히 원핵 숙주에서의 재조합 글리코실화 단백질 생산 방법 및 생산계
CA2818688A1 (en) * 2002-03-07 2003-09-12 Eidgenossische Technische Hochschule Zurich System and method for the production of recombinant glycosylated proteins in a prokaryotic host
WO2004096852A1 (fr) * 2003-04-25 2004-11-11 The Institute Of Microbiology And Epidemiology, Academy Of Military Medical Sciemces, Pla Interferon$g(v) humain recombinant, son procede d'expression et ses utilisations
CA2607595C (en) 2005-05-11 2018-11-27 Eth Zuerich Recombinant n-glycosylated proteins from procaryotic cells
SG10201400320TA (en) 2008-02-20 2014-05-29 Glycovaxyn Ag Bioconjugates made from recombinant n-glycosylated proteins from procaryotic cells
HUE038456T2 (hu) 2009-11-19 2018-10-29 Glaxosmithkline Biologicals Sa Bioszintetikus rendszer, amely immunogén poliszaccharidokat termel prokarióta sejtekben
HUE037956T2 (hu) 2010-05-06 2018-09-28 Glaxosmithkline Biologicals Sa Kapszuláris Gram-pozitív bakteriális biokonjugátum vakcinák
WO2013024158A1 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2014033266A1 (en) 2012-08-31 2014-03-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
AU1946283A (en) * 1982-08-18 1984-03-07 Cetus Corporation Interferon-alpha 6l
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
DE3574145D1 (en) * 1984-08-27 1989-12-14 Genentech Inc Novel, distinct family of human leukocyte interferons, compositions containing them, methods for their production, and dna and transfected hosts therefor

Also Published As

Publication number Publication date
GR851866B (fi) 1985-12-02
PT80901B (pt) 1989-01-17
HU205779B (en) 1992-06-29
ES8609475A1 (es) 1986-08-01
IL75963A0 (en) 1985-12-31
CA1340184C (en) 1998-12-15
DD246318A5 (de) 1987-06-03
ES545725A0 (es) 1986-08-01
IL75963A (en) 1992-05-25
EP0170204A2 (de) 1986-02-05
FI90667C (fi) 1994-03-10
KR870001310A (ko) 1987-03-13
NZ212937A (en) 1991-08-27
FI852956A0 (fi) 1985-07-31
ATE67786T1 (de) 1991-10-15
PT80901A (de) 1985-09-01
HK187896A (en) 1996-10-18
IE58942B1 (en) 1993-12-01
ES8708013A1 (es) 1987-09-01
NO177863C (no) 1995-12-06
DK346385A (da) 1986-02-02
EP0170204A3 (en) 1988-02-17
NO177863B (no) 1995-08-28
JPS61181381A (ja) 1986-08-14
AU600653B2 (en) 1990-08-23
FI90667B (fi) 1993-11-30
HUT39477A (en) 1986-09-29
JP2567195B2 (ja) 1996-12-25
EP0170204B1 (de) 1991-09-25
DK346385D0 (da) 1985-07-30
NO853012L (no) 1986-02-03
AU4554985A (en) 1986-02-06
KR0136799B1 (ko) 1998-04-25
FI852956L (fi) 1986-02-02
JPH06181771A (ja) 1994-07-05
MX9203645A (es) 1992-09-01
IE851906L (en) 1986-02-01
ES552431A0 (es) 1987-09-01
JP2566909B2 (ja) 1996-12-25
BG60445B2 (bg) 1995-03-31
DE3584198D1 (de) 1991-10-31

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