GR851866B - - Google Patents

Info

Publication number
GR851866B
GR851866B GR851866A GR850101866A GR851866B GR 851866 B GR851866 B GR 851866B GR 851866 A GR851866 A GR 851866A GR 850101866 A GR850101866 A GR 850101866A GR 851866 B GR851866 B GR 851866B
Authority
GR
Greece
Prior art keywords
interferons
organisms
produced
type
dna sequences
Prior art date
Application number
GR851866A
Other languages
English (en)
Inventor
Rudolf Hauptmann
Peter Meindl
Eva Dworkin-Rastl
Guenther Adolf
Peter Swetly
Christian Pieler
Norbert Hauel
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3428370A external-priority patent/DE3428370A1/de
Priority claimed from DE19853505060 external-priority patent/DE3505060A1/de
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of GR851866B publication Critical patent/GR851866B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
GR851866A 1984-08-01 1985-07-29 GR851866B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3428370A DE3428370A1 (de) 1984-08-01 1984-08-01 Interferon, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen
DE19853505060 DE3505060A1 (de) 1985-02-14 1985-02-14 Neue interferone vom typ i, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen

Publications (1)

Publication Number Publication Date
GR851866B true GR851866B (el) 1985-12-02

Family

ID=25823496

Family Applications (1)

Application Number Title Priority Date Filing Date
GR851866A GR851866B (el) 1984-08-01 1985-07-29

Country Status (21)

Country Link
EP (1) EP0170204B1 (el)
JP (2) JP2566909B2 (el)
KR (1) KR0136799B1 (el)
AT (1) ATE67786T1 (el)
AU (1) AU600653B2 (el)
BG (1) BG60445B2 (el)
CA (1) CA1340184C (el)
DD (1) DD246318A5 (el)
DE (1) DE3584198D1 (el)
DK (1) DK175194B1 (el)
ES (2) ES8609475A1 (el)
FI (1) FI90667C (el)
GR (1) GR851866B (el)
HK (1) HK187896A (el)
HU (1) HU205779B (el)
IE (1) IE58942B1 (el)
IL (1) IL75963A (el)
MX (1) MX9203645A (el)
NO (1) NO177863C (el)
NZ (1) NZ212937A (el)
PT (1) PT80901B (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231176A (en) * 1984-08-27 1993-07-27 Genentech, Inc. Distinct family DNA encoding of human leukocyte interferons
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
EP0490233A1 (de) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung
US4863727A (en) * 1986-04-09 1989-09-05 Cetus Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3633323A1 (de) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega
DE3635867A1 (de) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung
EP1987845B1 (en) 1997-11-20 2012-03-21 Vical Incorporated Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor.
WO2000040273A2 (en) * 1999-01-08 2000-07-13 Vical Incorporated Treatment of viral diseases using an interferon omega expressing polynucleotide
ES2258214T3 (es) 2002-03-07 2006-08-16 Eidgenossische Technische Hochschule Zurich Sistema y procedimiento para la produccion de proteinas glucosiladas recombinantes en un huesped procariotico.
JP4727927B2 (ja) * 2002-03-07 2011-07-20 アイトゲネシシェ・テッヒニシェ・ホーホシューレ・チューリッヒ 原核宿主における組換えグリコシル化タンパク質産生のためのシステムおよび方法
US20070026485A1 (en) 2003-04-09 2007-02-01 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
WO2004096852A1 (fr) * 2003-04-25 2004-11-11 The Institute Of Microbiology And Epidemiology, Academy Of Military Medical Sciemces, Pla Interferon$g(v) humain recombinant, son procede d'expression et ses utilisations
KR101524636B1 (ko) 2005-05-11 2015-06-03 에테하 취리히 원핵 세포로부터의 재조합 ｎ-글리코실화 단백질
SI2257307T1 (sl) 2008-02-20 2018-09-28 Glaxosmithkline Biologicals S.A. Biokonjugati, izdelani iz rekombinantnih N-glikoziliranih proteinov iz prokariontskih celic
PT2501406T (pt) 2009-11-19 2018-02-21 Glaxosmithkline Biologicals Sa Sistema de biossíntese que produz polissacáridos imunogénicos em células procariotas
ES2844596T3 (es) 2010-05-06 2021-07-22 Glaxosmithkline Biologicals Sa Vacunas de bioconjugados de bacterias grampositivas capsulares
WO2013024158A1 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2014033266A1 (en) 2012-08-31 2014-03-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1946283A (en) * 1982-08-18 1984-03-07 Cetus Corporation Interferon-alpha 6l
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
ATE47864T1 (de) * 1984-08-27 1989-11-15 Genentech Inc Verschiedenartige familie von menschlichen leukozyten-interferonen, zusammensetzungen, die diese enthalten, verfahren zu ihrer herstellung, sowie dna und transfektierte wirte hierfuer.

Also Published As

Publication number Publication date
DK346385D0 (da) 1985-07-30
DD246318A5 (de) 1987-06-03
NZ212937A (en) 1991-08-27
EP0170204B1 (de) 1991-09-25
PT80901B (pt) 1989-01-17
ATE67786T1 (de) 1991-10-15
HU205779B (en) 1992-06-29
JP2567195B2 (ja) 1996-12-25
NO177863C (no) 1995-12-06
HK187896A (en) 1996-10-18
AU4554985A (en) 1986-02-06
IL75963A0 (en) 1985-12-31
ES8708013A1 (es) 1987-09-01
NO177863B (no) 1995-08-28
BG60445B2 (bg) 1995-03-31
PT80901A (de) 1985-09-01
DE3584198D1 (de) 1991-10-31
JPH06181771A (ja) 1994-07-05
EP0170204A3 (en) 1988-02-17
FI90667C (fi) 1994-03-10
MX9203645A (es) 1992-09-01
HUT39477A (en) 1986-09-29
FI90667B (fi) 1993-11-30
IE58942B1 (en) 1993-12-01
IL75963A (en) 1992-05-25
FI852956A0 (fi) 1985-07-31
AU600653B2 (en) 1990-08-23
FI852956L (fi) 1986-02-02
ES8609475A1 (es) 1986-08-01
DK346385A (da) 1986-02-02
EP0170204A2 (de) 1986-02-05
JPS61181381A (ja) 1986-08-14
JP2566909B2 (ja) 1996-12-25
ES552431A0 (es) 1987-09-01
NO853012L (no) 1986-02-03
ES545725A0 (es) 1986-08-01
KR0136799B1 (ko) 1998-04-25
KR870001310A (ko) 1987-03-13
CA1340184C (en) 1998-12-15
DK175194B1 (da) 2004-07-05
IE851906L (en) 1986-02-01

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