FI852956L - Menetelmä valmistaa uutta ihmisen tyypin I interferoniproteiinia - Google Patents

Menetelmä valmistaa uutta ihmisen tyypin I interferoniproteiinia

Info

Publication number
FI852956L
FI852956L FI852956A FI852956A FI852956L FI 852956 L FI852956 L FI 852956L FI 852956 A FI852956 A FI 852956A FI 852956 A FI852956 A FI 852956A FI 852956 L FI852956 L FI 852956L
Authority
FI
Finland
Prior art keywords
method produces
novel human
human type
interferon protein
interferon
Prior art date
Application number
FI852956A
Other languages
English (en)
Swedish (sv)
Other versions
FI90667C (fi
FI90667B (fi
FI852956A0 (fi
Inventor
Rudolf Hauptmann
Peter Meindl
Eva Rastl-Dworkin
Guenther Adolf
Peter Swetly
Christian Pieler
Norbert Hauel
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3428370A external-priority patent/DE3428370A1/de
Priority claimed from DE19853505060 external-priority patent/DE3505060A1/de
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of FI852956A0 publication Critical patent/FI852956A0/fi
Publication of FI852956L publication Critical patent/FI852956L/fi
Application granted granted Critical
Publication of FI90667B publication Critical patent/FI90667B/fi
Publication of FI90667C publication Critical patent/FI90667C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
FI852956A 1984-08-01 1985-07-31 Menetelmä valmistaa uutta ihmisen tyypin I interferoniproteiinia FI90667C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3428370 1984-08-01
DE3428370A DE3428370A1 (de) 1984-08-01 1984-08-01 Interferon, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen
DE3505060 1985-02-14
DE19853505060 DE3505060A1 (de) 1985-02-14 1985-02-14 Neue interferone vom typ i, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen

Publications (4)

Publication Number Publication Date
FI852956A0 FI852956A0 (fi) 1985-07-31
FI852956L true FI852956L (fi) 1986-02-02
FI90667B FI90667B (fi) 1993-11-30
FI90667C FI90667C (fi) 1994-03-10

Family

ID=25823496

Family Applications (1)

Application Number Title Priority Date Filing Date
FI852956A FI90667C (fi) 1984-08-01 1985-07-31 Menetelmä valmistaa uutta ihmisen tyypin I interferoniproteiinia

Country Status (21)

Country Link
EP (1) EP0170204B1 (fi)
JP (2) JP2566909B2 (fi)
KR (1) KR0136799B1 (fi)
AT (1) ATE67786T1 (fi)
AU (1) AU600653B2 (fi)
BG (1) BG60445B2 (fi)
CA (1) CA1340184C (fi)
DD (1) DD246318A5 (fi)
DE (1) DE3584198D1 (fi)
DK (1) DK175194B1 (fi)
ES (2) ES8609475A1 (fi)
FI (1) FI90667C (fi)
GR (1) GR851866B (fi)
HK (1) HK187896A (fi)
HU (1) HU205779B (fi)
IE (1) IE58942B1 (fi)
IL (1) IL75963A (fi)
MX (1) MX9203645A (fi)
NO (1) NO177863C (fi)
NZ (1) NZ212937A (fi)
PT (1) PT80901B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231176A (en) * 1984-08-27 1993-07-27 Genentech, Inc. Distinct family DNA encoding of human leukocyte interferons
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
EP0490233A1 (de) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung
US4863727A (en) * 1986-04-09 1989-09-05 Cetus Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3633323A1 (de) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega
DE3635867A1 (de) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung
JP2001523480A (ja) 1997-11-20 2001-11-27 バイカル インコーポレイテッド サイトカイン発現ポリヌクレオチドおよびそれらの組成物を用いた癌の処置
WO2000040273A2 (en) * 1999-01-08 2000-07-13 Vical Incorporated Treatment of viral diseases using an interferon omega expressing polynucleotide
CA2477794C (en) 2002-03-07 2013-08-20 Eidgenoessische Technische Hochschule Zuerich System and method for the production of recombinant glycosylated proteins in a prokaryotic host
US20040265954A1 (en) * 2002-03-07 2004-12-30 Markus Aebi System and method for the production of recombinant proteins
MXPA05010773A (es) 2003-04-09 2005-12-12 Neose Technologies Inc Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos.
WO2004096852A1 (fr) * 2003-04-25 2004-11-11 The Institute Of Microbiology And Epidemiology, Academy Of Military Medical Sciemces, Pla Interferon$g(v) humain recombinant, son procede d'expression et ses utilisations
PT2311972E (pt) 2005-05-11 2015-05-13 Eth Zuerich Proteínas n-glicosiladas recombinantes de células procarióticas
CA2716187C (en) 2008-02-20 2020-01-07 Glycovaxyn Ag Bioconjugates made from recombinant n-glycosylated proteins from procaryotic cells
NO2501406T3 (fi) 2009-11-19 2018-05-19
HUE037956T2 (hu) 2010-05-06 2018-09-28 Glaxosmithkline Biologicals Sa Kapszuláris Gram-pozitív bakteriális biokonjugátum vakcinák
WO2013024158A1 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2014033266A1 (en) 2012-08-31 2014-03-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1946283A (en) * 1982-08-18 1984-03-07 Cetus Corporation Interferon-alpha 6l
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
DE3574145D1 (en) * 1984-08-27 1989-12-14 Genentech Inc Novel, distinct family of human leukocyte interferons, compositions containing them, methods for their production, and dna and transfected hosts therefor

Also Published As

Publication number Publication date
JP2566909B2 (ja) 1996-12-25
AU600653B2 (en) 1990-08-23
ATE67786T1 (de) 1991-10-15
EP0170204B1 (de) 1991-09-25
HU205779B (en) 1992-06-29
PT80901B (pt) 1989-01-17
GR851866B (fi) 1985-12-02
JPH06181771A (ja) 1994-07-05
DE3584198D1 (de) 1991-10-31
PT80901A (de) 1985-09-01
DD246318A5 (de) 1987-06-03
HK187896A (en) 1996-10-18
IL75963A (en) 1992-05-25
FI90667C (fi) 1994-03-10
DK346385D0 (da) 1985-07-30
MX9203645A (es) 1992-09-01
NZ212937A (en) 1991-08-27
DK175194B1 (da) 2004-07-05
AU4554985A (en) 1986-02-06
NO853012L (no) 1986-02-03
CA1340184C (en) 1998-12-15
DK346385A (da) 1986-02-02
KR870001310A (ko) 1987-03-13
IE851906L (en) 1986-02-01
NO177863C (no) 1995-12-06
BG60445B2 (bg) 1995-03-31
IE58942B1 (en) 1993-12-01
KR0136799B1 (ko) 1998-04-25
JPS61181381A (ja) 1986-08-14
JP2567195B2 (ja) 1996-12-25
EP0170204A3 (en) 1988-02-17
IL75963A0 (en) 1985-12-31
FI90667B (fi) 1993-11-30
ES8708013A1 (es) 1987-09-01
FI852956A0 (fi) 1985-07-31
NO177863B (no) 1995-08-28
HUT39477A (en) 1986-09-29
ES8609475A1 (es) 1986-08-01
ES545725A0 (es) 1986-08-01
EP0170204A2 (de) 1986-02-05
ES552431A0 (es) 1987-09-01

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BB Publication of examined application
FG Patent granted

Owner name: BOEHRINGER INGELHEIM INTERNATIONAL GMBH

MA Patent expired