DK175037B1 - Fremgangsmåde til fremstilling af quinolincarboxylsyrederivater samt mellemprodukt, der kan anvendes ved fremgangsmåden - Google Patents
Fremgangsmåde til fremstilling af quinolincarboxylsyrederivater samt mellemprodukt, der kan anvendes ved fremgangsmåden Download PDFInfo
- Publication number
- DK175037B1 DK175037B1 DK198806822A DK682288A DK175037B1 DK 175037 B1 DK175037 B1 DK 175037B1 DK 198806822 A DK198806822 A DK 198806822A DK 682288 A DK682288 A DK 682288A DK 175037 B1 DK175037 B1 DK 175037B1
- Authority
- DK
- Denmark
- Prior art keywords
- general formula
- acid
- process according
- compound
- piperazinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU150587 | 1987-04-08 | ||
HU871505A HU198709B (en) | 1987-04-08 | 1987-04-08 | Process for producing quinoline-carboxylic acid derivatives |
HU8800019 | 1988-04-08 | ||
PCT/HU1988/000019 WO1988007993A1 (en) | 1987-04-08 | 1988-04-08 | Process for the preparation of quinoline carboxylic acids |
Publications (3)
Publication Number | Publication Date |
---|---|
DK682288D0 DK682288D0 (da) | 1988-12-07 |
DK682288A DK682288A (da) | 1988-12-07 |
DK175037B1 true DK175037B1 (da) | 2004-05-10 |
Family
ID=10954767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198806822A DK175037B1 (da) | 1987-04-08 | 1988-12-07 | Fremgangsmåde til fremstilling af quinolincarboxylsyrederivater samt mellemprodukt, der kan anvendes ved fremgangsmåden |
Country Status (13)
Country | Link |
---|---|
US (2) | US5091530A (cs) |
EP (1) | EP0309537B1 (cs) |
JP (1) | JP2693987B2 (cs) |
CN (1) | CN1025616C (cs) |
AT (1) | ATE124687T1 (cs) |
AU (1) | AU612648B2 (cs) |
CS (1) | CS274460B2 (cs) |
DD (1) | DD269848A5 (cs) |
DE (1) | DE3854109T2 (cs) |
DK (1) | DK175037B1 (cs) |
HU (1) | HU198709B (cs) |
SU (1) | SU1701110A3 (cs) |
WO (1) | WO1988007993A1 (cs) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU198709B (en) * | 1987-04-08 | 1989-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing quinoline-carboxylic acid derivatives |
HU203746B (en) * | 1988-12-22 | 1991-09-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing quinoline-carboxylic acid derivatives |
JPH0778065B2 (ja) * | 1990-07-06 | 1995-08-23 | 杏林製薬株式会社 | (6,7―置換―8―アルコキシ―1―シクロプロピル―1,4―ジヒドロ―4―オキソ―3―キノリンカルボン酸―o▲上3▼,o▲上4▼)ビス(アシルオキシ―o)ホウ素化合物及びその塩並びにその製造方法 |
GB9118183D0 (en) * | 1991-08-23 | 1991-10-09 | Solanki Kishor K | Imaging of infections |
US5440061A (en) * | 1994-03-29 | 1995-08-08 | The Procter & Gamble Company | Hydrolysis of methyl esters in dimethylsulfoxide for production of fatty acids |
NZ260530A (en) * | 1994-05-16 | 1997-06-24 | Nigel Paul Maynard | Organoborate complexes of divalent metal; use as timber treament agents |
ES2092963B1 (es) * | 1995-04-12 | 1997-12-16 | Sint Quimica Sa | Procedimiento para la preparacion del acido 1-ciclopropil-6-fluoro-1, 4-dihidro-7-(1s,4s)-5-metil-2,5-diazabiciclo(2.2.1) hept-2-il)-4-oxo-3-quinolincarboxilico y sus sales. |
ES2095809B1 (es) * | 1995-07-27 | 1997-12-16 | Sint Quimica Sa | Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales. |
CN101195614B (zh) * | 2006-12-04 | 2011-10-26 | 河南康泰制药集团公司 | 一种巴洛沙星的制备及纯化方法 |
CN101671302B (zh) * | 2008-12-30 | 2011-03-30 | 广东海康兽药有限公司 | 禽畜用抗菌药恩诺沙星的生产工艺 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
DE3142854A1 (de) * | 1981-10-29 | 1983-05-11 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
DE3033157A1 (de) * | 1980-09-03 | 1982-04-01 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
JPS5980683A (ja) * | 1982-10-30 | 1984-05-10 | Koei Chem Co Ltd | 6−フルオロ−1,8−ナフチリジン誘導体およびその製造法 |
JPS59122470A (ja) * | 1982-12-27 | 1984-07-14 | Dai Ichi Seiyaku Co Ltd | キノリン−3−カルボン酸誘導体の製造法 |
JPS6075489A (ja) * | 1983-10-03 | 1985-04-27 | Dai Ichi Seiyaku Co Ltd | ホウ素キレ−ト化合物 |
JPS6078986A (ja) * | 1983-10-07 | 1985-05-04 | Dai Ichi Seiyaku Co Ltd | オキサジン誘導体の製法 |
JPS60126290A (ja) * | 1983-12-13 | 1985-07-05 | Dai Ichi Seiyaku Co Ltd | ホウ素キレ−ト化合物の製造法 |
HU196782B (en) * | 1985-12-09 | 1989-01-30 | Chinoin Gyogyszer Es Vegyeszet | Process for production of quinoline carbonic acid |
HU196218B (en) * | 1985-12-09 | 1988-10-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing quinoline carboxylic acid boric acid anhydrides |
HU196415B (en) * | 1985-12-09 | 1988-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing quinoline carboxylic acid boric acid anhydrides |
US4940710A (en) * | 1986-01-17 | 1990-07-10 | American Cyanamid Company | 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids |
YU46451B (sh) * | 1987-04-08 | 1993-10-20 | Chinoin Gyogyszer Es Vegyeszeti Ter Mekek Gyara Rt. | Postupak za dobivanje mešovitih anhidrida hinolin-karboksilne i borne kiseline |
HU198709B (en) * | 1987-04-08 | 1989-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing quinoline-carboxylic acid derivatives |
JP2693988B2 (ja) * | 1987-06-24 | 1997-12-24 | キノイン ギオギスゼル エス ベギエスゼチ テルメケク ギヤラ アールティー. | キノリンカルボン酸誘導体の製造方法 |
JPS6419069A (en) * | 1987-07-14 | 1989-01-23 | Dainippon Pharmaceutical Co | Production of polyhalogenoquinoline derivative |
-
1987
- 1987-04-08 HU HU871505A patent/HU198709B/hu unknown
-
1988
- 1988-04-07 DD DD88314509A patent/DD269848A5/de not_active IP Right Cessation
- 1988-04-07 CN CN88101907A patent/CN1025616C/zh not_active Expired - Lifetime
- 1988-04-08 US US07/290,105 patent/US5091530A/en not_active Expired - Lifetime
- 1988-04-08 DE DE3854109T patent/DE3854109T2/de not_active Expired - Lifetime
- 1988-04-08 AT AT88903335T patent/ATE124687T1/de not_active IP Right Cessation
- 1988-04-08 WO PCT/HU1988/000019 patent/WO1988007993A1/en active IP Right Grant
- 1988-04-08 CS CS242088A patent/CS274460B2/cs not_active IP Right Cessation
- 1988-04-08 JP JP63503085A patent/JP2693987B2/ja not_active Expired - Lifetime
- 1988-04-08 EP EP88903335A patent/EP0309537B1/en not_active Expired - Lifetime
- 1988-04-08 AU AU15721/88A patent/AU612648B2/en not_active Expired
- 1988-12-07 SU SU884613033A patent/SU1701110A3/ru active
- 1988-12-07 DK DK198806822A patent/DK175037B1/da not_active IP Right Cessation
-
1991
- 1991-09-06 US US07/756,345 patent/US5300644A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0309537B1 (en) | 1995-07-05 |
EP0309537A1 (en) | 1989-04-05 |
CS274460B2 (en) | 1991-04-11 |
ATE124687T1 (de) | 1995-07-15 |
US5300644A (en) | 1994-04-05 |
DD269848A5 (de) | 1989-07-12 |
WO1988007993A1 (en) | 1988-10-20 |
HUT46686A (en) | 1988-11-28 |
DE3854109T2 (de) | 1995-11-30 |
CN1025616C (zh) | 1994-08-10 |
JPH01503301A (ja) | 1989-11-09 |
JP2693987B2 (ja) | 1997-12-24 |
DK682288D0 (da) | 1988-12-07 |
SU1701110A3 (ru) | 1991-12-23 |
CS242088A2 (en) | 1990-09-12 |
DE3854109D1 (de) | 1995-08-10 |
HU198709B (en) | 1989-11-28 |
CN88101907A (zh) | 1988-10-26 |
AU612648B2 (en) | 1991-07-18 |
AU1572188A (en) | 1988-11-04 |
DK682288A (da) | 1988-12-07 |
US5091530A (en) | 1992-02-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |