ES2095809B1 - Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales. - Google Patents

Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales.

Info

Publication number
ES2095809B1
ES2095809B1 ES09501512A ES9501512A ES2095809B1 ES 2095809 B1 ES2095809 B1 ES 2095809B1 ES 09501512 A ES09501512 A ES 09501512A ES 9501512 A ES9501512 A ES 9501512A ES 2095809 B1 ES2095809 B1 ES 2095809B1
Authority
ES
Spain
Prior art keywords
naftiridin
procedure
salts
preparation
carboxylic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES09501512A
Other languages
English (en)
Other versions
ES2095809A1 (es
Inventor
Darder Carlos Picornell
Hernandez Pedro Gonzalez
Gomez Antonio Cosme
Gonzalez Maria Luisa Salas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quimica Sintetica SA
Original Assignee
Quimica Sintetica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quimica Sintetica SA filed Critical Quimica Sintetica SA
Priority to ES09501512A priority Critical patent/ES2095809B1/es
Priority to CZ962047A priority patent/CZ204796A3/cs
Priority to NO962906A priority patent/NO962906L/no
Priority to GR960100244A priority patent/GR960100244A/el
Priority to FI962852A priority patent/FI962852A/fi
Priority to SK923-96A priority patent/SK92396A3/sk
Priority to ARP960103597A priority patent/AR002848A1/es
Priority to PT101897A priority patent/PT101897B/pt
Priority to CO96038187A priority patent/CO4700471A1/es
Priority to MX9602953A priority patent/MX9602953A/es
Priority to KR1019960030206A priority patent/KR970006303A/ko
Priority to PL96315423A priority patent/PL315423A1/xx
Priority to HU9602071A priority patent/HUP9602071A3/hu
Publication of ES2095809A1 publication Critical patent/ES2095809A1/es
Application granted granted Critical
Publication of ES2095809B1 publication Critical patent/ES2095809B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE ACIDOS NAFTIRIDIN CARBOXILICOS Y SUS SALES. LA PRESENTE INVENCION TIENE POR OBJETO UN PROCEDIMIENTO PARA LA OBTENCION DE NAFTIRIDINAS DE FORMULA GENERAL 1, EN LAS QUE R ES IGUAL A 3-AMINOPIRROLIDIN-1-ILO (TOSUFLOXACINO O ACIDO (RS) - 7 (3-AMINOPIRROLIDIN-1-IL) -6-FLUORO-1- (2,4-DIFLUOROFENIL) -1,4- DIHIDRO-4-OXO-1,8 -NAFTIRIDIN-3-CARBOXILICO (1A) O A (1AL,5AL,6AL) - 6-AMINO-3-AZABICICLO [3.1.0] HEX-3-ILO (TROVAFLOXACINO O ACIDO 7-[(1AL,5AL,6AL) - 6 AMINO-3- AZABICICLO [3.1.0] HEX-3-IL) -6-FLUORO-1- (2,4-DIFLUOROFENIL) - 1,4-DIHIDRO-4-OXO-1,8 -NAFTIRIDIN-3-CARBOXILICO (1B)] Y SUS HIDRATOS Y SALES RESPECTIVAS, COMPUESTOS DE SINTESIS CON INTERESANTES PROPIEDADES TERAPEUTICAS QUE PERTENECEN A LA FAMILIA DE LAS FLUOROQUINOLONAS DE ACCION ANTIBACTERIANA.
ES09501512A 1995-07-27 1995-07-27 Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales. Expired - Lifetime ES2095809B1 (es)

Priority Applications (13)

Application Number Priority Date Filing Date Title
ES09501512A ES2095809B1 (es) 1995-07-27 1995-07-27 Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales.
CZ962047A CZ204796A3 (en) 1995-07-27 1996-07-10 Process for preparing naphthyridinecarboxylic acids and salts thereof
NO962906A NO962906L (no) 1995-07-27 1996-07-10 Fremgangsmåte til fremstilling av naftyridinkarboksylsyrer og deres salter
GR960100244A GR960100244A (el) 1995-07-27 1996-07-12 Μεθοδος για την παρασκευη ναφθυριδινοκαρβοξυλικων οξεων και των αλατων τους.
FI962852A FI962852A (fi) 1995-07-27 1996-07-15 Menetelmä naftyridiinikarboksyylihappojen ja niiden suolojen valmistamiseksi
ARP960103597A AR002848A1 (es) 1995-07-27 1996-07-16 Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales particularmente utiles por su accion antibacteriana.
SK923-96A SK92396A3 (en) 1995-07-27 1996-07-16 Process for the preparation of naphtyridinecarboxylic acids and their salts
PT101897A PT101897B (pt) 1995-07-27 1996-07-18 Processo para a preparacao de acidos naftiridinocarboxilicos e seus sais
CO96038187A CO4700471A1 (es) 1995-07-27 1996-07-19 Procedimiento para la preparacion de acidos naftiridin car- boxilicos y sus sales
MX9602953A MX9602953A (es) 1995-07-27 1996-07-23 Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales.
KR1019960030206A KR970006303A (ko) 1995-07-27 1996-07-25 나프티리딘카복실산 및 이의 염의 제조방법
PL96315423A PL315423A1 (en) 1995-07-27 1996-07-26 Method of obtaining naphtyridinocarboxylic acids and their salts
HU9602071A HUP9602071A3 (en) 1995-07-27 1996-07-26 New process for preparing naphthridinecarboxilic acids and their salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09501512A ES2095809B1 (es) 1995-07-27 1995-07-27 Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales.

Publications (2)

Publication Number Publication Date
ES2095809A1 ES2095809A1 (es) 1997-02-16
ES2095809B1 true ES2095809B1 (es) 1997-12-16

Family

ID=8291178

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09501512A Expired - Lifetime ES2095809B1 (es) 1995-07-27 1995-07-27 Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales.

Country Status (13)

Country Link
KR (1) KR970006303A (es)
AR (1) AR002848A1 (es)
CO (1) CO4700471A1 (es)
CZ (1) CZ204796A3 (es)
ES (1) ES2095809B1 (es)
FI (1) FI962852A (es)
GR (1) GR960100244A (es)
HU (1) HUP9602071A3 (es)
MX (1) MX9602953A (es)
NO (1) NO962906L (es)
PL (1) PL315423A1 (es)
PT (1) PT101897B (es)
SK (1) SK92396A3 (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198709B (en) * 1987-04-08 1989-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing quinoline-carboxylic acid derivatives
NZ224150A (en) * 1987-04-08 1990-11-27 Chinoin Gyogyszer Es Vegyeszet Preparation of piperazinyl-substituted quinoline derivatives
JP2693988B2 (ja) * 1987-06-24 1997-12-24 キノイン ギオギスゼル エス ベギエスゼチ テルメケク ギヤラ アールティー． キノリンカルボン酸誘導体の製造方法
IE62600B1 (en) * 1987-08-04 1995-02-22 Abbott Lab Naphtyridine antianaerobic compounds
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
ES2020786A6 (es) * 1990-07-19 1991-09-16 Inke Sa Procedimiento para la obtencion del acido (+-)-7-(3-amino-1-pirrolidinil)-1-(2-4-difluorofenil)-6-fluoro-1,4-dihidro-4-oxo-1,8-naftiridin-3-carboxilico y sus sales.
AU694149B2 (en) * 1994-01-18 1998-07-16 Pfizer Inc. Process and intermediates for preparing naphthyridonecarboxylic acid salts

Also Published As

Publication number Publication date
HUP9602071A3 (en) 2000-03-28
GR960100244A (el) 1997-03-31
FI962852A0 (fi) 1996-07-15
SK92396A3 (en) 1997-06-04
ES2095809A1 (es) 1997-02-16
FI962852A (fi) 1997-01-28
PT101897A (pt) 1997-06-30
PL315423A1 (en) 1997-02-03
MX9602953A (es) 1997-06-28
CZ204796A3 (en) 1997-02-12
KR970006303A (ko) 1997-02-19
AR002848A1 (es) 1998-04-29
NO962906L (no) 1997-01-28
CO4700471A1 (es) 1998-12-29
HU9602071D0 (en) 1996-09-30
NO962906D0 (no) 1996-07-10
HUP9602071A2 (en) 1997-03-28
PT101897B (pt) 1999-07-30

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