DE69927251D1 - Verfahren zur herstellung von purinderivaten und dessen zwischenprodukte - Google Patents
Verfahren zur herstellung von purinderivaten und dessen zwischenprodukteInfo
- Publication number
- DE69927251D1 DE69927251D1 DE69927251T DE69927251T DE69927251D1 DE 69927251 D1 DE69927251 D1 DE 69927251D1 DE 69927251 T DE69927251 T DE 69927251T DE 69927251 T DE69927251 T DE 69927251T DE 69927251 D1 DE69927251 D1 DE 69927251D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- intermediate products
- purine derivatives
- penciclovir
- famciclovir
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9807114.5A GB9807114D0 (en) | 1998-04-02 | 1998-04-02 | Novel process |
| GB9807114 | 1998-04-02 | ||
| PCT/EP1999/002308 WO1999051603A1 (en) | 1998-04-02 | 1999-03-30 | Process for the production of purine derivatives and intermediates therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69927251D1 true DE69927251D1 (de) | 2005-10-20 |
| DE69927251T2 DE69927251T2 (de) | 2006-06-29 |
Family
ID=10829763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69927251T Expired - Fee Related DE69927251T2 (de) | 1998-04-02 | 1999-03-30 | Verfahren zur herstellung von purinderivaten und dessen zwischenprodukte |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US6555685B1 (de) |
| EP (1) | EP1068209B1 (de) |
| JP (1) | JP4524040B2 (de) |
| KR (1) | KR100701114B1 (de) |
| CN (1) | CN1153769C (de) |
| AT (1) | ATE304541T1 (de) |
| AU (1) | AU3420099A (de) |
| BR (1) | BR9908964A (de) |
| CA (1) | CA2322583A1 (de) |
| DE (1) | DE69927251T2 (de) |
| DK (1) | DK1068209T3 (de) |
| ES (1) | ES2247793T3 (de) |
| GB (1) | GB9807114D0 (de) |
| HK (1) | HK1034512A1 (de) |
| IL (1) | IL138288A (de) |
| WO (1) | WO1999051603A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1288215B8 (de) | 2001-08-30 | 2005-04-06 | Ajinomoto Co., Inc. | Herstellungsmethode von Famciclovir und Herstellungs- bzw. Kristallisationsmethode eines entsprechenden Intermediates |
| US20040097528A1 (en) * | 2002-08-26 | 2004-05-20 | Ben-Zion Dolitzky | Crystalline solid famciclovir forms I, II, III and preparation thereof |
| WO2004099208A1 (en) * | 2003-04-30 | 2004-11-18 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of famciclovir |
| EP1556383A1 (de) * | 2003-09-04 | 2005-07-27 | Teva Pharmaceutical Industries Ltd. | Verfahren zur herstellung von famciclovir |
| WO2005103025A1 (en) * | 2004-04-21 | 2005-11-03 | Novogen Research Pty Ltd | Isoflavene synthetic method and catalyst |
| GB2426247A (en) * | 2005-05-20 | 2006-11-22 | Arrow Int Ltd | Methods of preparing purine derivatives such as famciclovir |
| ES2537628T3 (es) | 2010-08-27 | 2015-06-10 | Grünenthal GmbH | 2-Oxiquinolin-3-carboxamidas sustituidas como moduladores de KCNQ2/3 |
| CN103189357B (zh) | 2010-08-27 | 2015-11-25 | 格吕伦塔尔有限公司 | 作为kcnq2/3调节剂的取代的2-氧代-和2-硫代-二氢喹啉-3-甲酰胺 |
| JP5887345B2 (ja) | 2010-08-27 | 2016-03-16 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | Ｋｃｎｑ２／３調節因子としての置換２−アミノ−キノリン−３−カルボキサミド |
| US8618129B2 (en) | 2010-09-01 | 2013-12-31 | Gruenenthal Gmbh | Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as KCNQ2/3 modulators |
| CN102070636B (zh) * | 2011-01-17 | 2012-05-23 | 浙江大学 | 喷昔洛韦的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL73682A (en) | 1983-12-20 | 1991-08-16 | Medivir Ab | Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation |
| SE8406538D0 (sv) | 1984-12-21 | 1984-12-21 | Astra Laekemedel Ab | Novel derivatives of purine |
| GB8817607D0 (en) | 1988-07-23 | 1988-09-01 | Beecham Group Plc | Novel process |
| JPH06279443A (ja) * | 1993-01-27 | 1994-10-04 | Asahi Chem Ind Co Ltd | ６’−ホモネプラノシンａ誘導体およびその製造法 |
| GB9407698D0 (en) * | 1994-04-19 | 1994-06-15 | Smithkline Beecham Plc | Pharmaceuticals |
-
1998
- 1998-04-02 GB GBGB9807114.5A patent/GB9807114D0/en not_active Ceased
-
1999
- 1999-03-30 WO PCT/EP1999/002308 patent/WO1999051603A1/en active IP Right Grant
- 1999-03-30 CA CA002322583A patent/CA2322583A1/en not_active Abandoned
- 1999-03-30 IL IL13828899A patent/IL138288A/xx not_active IP Right Cessation
- 1999-03-30 KR KR1020007010707A patent/KR100701114B1/ko not_active IP Right Cessation
- 1999-03-30 AU AU34200/99A patent/AU3420099A/en not_active Abandoned
- 1999-03-30 AT AT99915738T patent/ATE304541T1/de not_active IP Right Cessation
- 1999-03-30 US US09/623,662 patent/US6555685B1/en not_active Expired - Lifetime
- 1999-03-30 ES ES99915738T patent/ES2247793T3/es not_active Expired - Lifetime
- 1999-03-30 EP EP99915738A patent/EP1068209B1/de not_active Expired - Lifetime
- 1999-03-30 DE DE69927251T patent/DE69927251T2/de not_active Expired - Fee Related
- 1999-03-30 BR BR9908964-5A patent/BR9908964A/pt active Search and Examination
- 1999-03-30 JP JP2000542324A patent/JP4524040B2/ja not_active Expired - Fee Related
- 1999-03-30 DK DK99915738T patent/DK1068209T3/da active
- 1999-03-30 CN CNB998044008A patent/CN1153769C/zh not_active Expired - Fee Related
-
2001
- 2001-07-17 HK HK01105015A patent/HK1034512A1/xx not_active IP Right Cessation
-
2003
- 2003-02-19 US US10/369,841 patent/US6806375B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20030130512A1 (en) | 2003-07-10 |
| AU3420099A (en) | 1999-10-25 |
| ATE304541T1 (de) | 2005-09-15 |
| GB9807114D0 (en) | 1998-06-03 |
| CN1153769C (zh) | 2004-06-16 |
| IL138288A (en) | 2005-07-25 |
| CN1294589A (zh) | 2001-05-09 |
| IL138288A0 (en) | 2001-10-31 |
| WO1999051603A1 (en) | 1999-10-14 |
| EP1068209B1 (de) | 2005-09-14 |
| KR100701114B1 (ko) | 2007-03-29 |
| ES2247793T3 (es) | 2006-03-01 |
| HK1034512A1 (en) | 2001-10-26 |
| CA2322583A1 (en) | 1999-10-14 |
| KR20010034702A (ko) | 2001-04-25 |
| DK1068209T3 (da) | 2005-11-14 |
| JP2002510691A (ja) | 2002-04-09 |
| EP1068209A1 (de) | 2001-01-17 |
| DE69927251T2 (de) | 2006-06-29 |
| BR9908964A (pt) | 2000-12-05 |
| US6806375B2 (en) | 2004-10-19 |
| JP4524040B2 (ja) | 2010-08-11 |
| US6555685B1 (en) | 2003-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
| R082 | Change of representative |
Ref document number: 1068209 Country of ref document: EP Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN, DE |
|
| R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee |
Ref document number: 1068209 Country of ref document: EP Effective date: 20111001 |