ATE304541T1 - Verfahren zur herstellung von purinderivaten und dessen zwischenprodukte - Google Patents

Verfahren zur herstellung von purinderivaten und dessen zwischenprodukte

Info

Publication number
ATE304541T1
ATE304541T1 AT99915738T AT99915738T ATE304541T1 AT E304541 T1 ATE304541 T1 AT E304541T1 AT 99915738 T AT99915738 T AT 99915738T AT 99915738 T AT99915738 T AT 99915738T AT E304541 T1 ATE304541 T1 AT E304541T1
Authority
AT
Austria
Prior art keywords
intermediate products
purine derivatives
producing purine
producing
derivatives
Prior art date
Application number
AT99915738T
Other languages
English (en)
Inventor
Richard Freer
Graham Richard Geen
Thomas Weir Ramsay
Andrew Colin Share
Neil Michael Smith
Original Assignee
Novartis Int Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Int Pharm Ltd filed Critical Novartis Int Pharm Ltd
Application granted granted Critical
Publication of ATE304541T1 publication Critical patent/ATE304541T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT99915738T 1998-04-02 1999-03-30 Verfahren zur herstellung von purinderivaten und dessen zwischenprodukte ATE304541T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9807114.5A GB9807114D0 (en) 1998-04-02 1998-04-02 Novel process
PCT/EP1999/002308 WO1999051603A1 (en) 1998-04-02 1999-03-30 Process for the production of purine derivatives and intermediates therefor

Publications (1)

Publication Number Publication Date
ATE304541T1 true ATE304541T1 (de) 2005-09-15

Family

ID=10829763

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99915738T ATE304541T1 (de) 1998-04-02 1999-03-30 Verfahren zur herstellung von purinderivaten und dessen zwischenprodukte

Country Status (16)

Country Link
US (2) US6555685B1 (de)
EP (1) EP1068209B1 (de)
JP (1) JP4524040B2 (de)
KR (1) KR100701114B1 (de)
CN (1) CN1153769C (de)
AT (1) ATE304541T1 (de)
AU (1) AU3420099A (de)
BR (1) BR9908964A (de)
CA (1) CA2322583A1 (de)
DE (1) DE69927251T2 (de)
DK (1) DK1068209T3 (de)
ES (1) ES2247793T3 (de)
GB (1) GB9807114D0 (de)
HK (1) HK1034512A1 (de)
IL (1) IL138288A (de)
WO (1) WO1999051603A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1288215B8 (de) 2001-08-30 2005-04-06 Ajinomoto Co., Inc. Herstellungsmethode von Famciclovir und Herstellungs- bzw. Kristallisationsmethode eines entsprechenden Intermediates
AU2003268213A1 (en) * 2002-08-26 2004-03-11 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
US20040266795A1 (en) * 2003-04-30 2004-12-30 Genny Shamai Process for the preparation of famciclovir
US20050143400A1 (en) * 2003-09-04 2005-06-30 Genny Shamai Process for preparing famciclovir
WO2005103025A1 (en) * 2004-04-21 2005-11-03 Novogen Research Pty Ltd Isoflavene synthetic method and catalyst
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir
US8653101B2 (en) 2010-08-27 2014-02-18 Gruenenthal Gmbh Substituted 2-oxy-quinoline-3-carboxamides as KCNQ2/3 modulators
CA2805932A1 (en) 2010-08-27 2012-03-01 Gruenenthal Gmbh Substituted 2-amino-quinoline-3-carboxamides as kcnq2/3 modulators
MX342459B (es) 2010-08-27 2016-09-29 Grünenthal Gmbh * 2-oxo- y 2-tioxo-dihidroquinolin-3-carboxamidas sustituidas, como moduladores de kcnq2/3.
AU2011297937B2 (en) 2010-09-01 2015-10-01 Grunenthal Gmbh Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as KCNQ2/3 modulators
CN102070636B (zh) * 2011-01-17 2012-05-23 浙江大学 喷昔洛韦的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
SE8406538D0 (sv) 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
GB8817607D0 (en) 1988-07-23 1988-09-01 Beecham Group Plc Novel process
JPH06279443A (ja) * 1993-01-27 1994-10-04 Asahi Chem Ind Co Ltd 6’−ホモネプラノシンa誘導体およびその製造法
GB9407698D0 (en) * 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals

Also Published As

Publication number Publication date
AU3420099A (en) 1999-10-25
HK1034512A1 (en) 2001-10-26
ES2247793T3 (es) 2006-03-01
KR20010034702A (ko) 2001-04-25
JP4524040B2 (ja) 2010-08-11
BR9908964A (pt) 2000-12-05
US6806375B2 (en) 2004-10-19
DK1068209T3 (da) 2005-11-14
WO1999051603A1 (en) 1999-10-14
GB9807114D0 (en) 1998-06-03
US6555685B1 (en) 2003-04-29
DE69927251D1 (de) 2005-10-20
KR100701114B1 (ko) 2007-03-29
US20030130512A1 (en) 2003-07-10
IL138288A0 (en) 2001-10-31
EP1068209B1 (de) 2005-09-14
CA2322583A1 (en) 1999-10-14
DE69927251T2 (de) 2006-06-29
IL138288A (en) 2005-07-25
EP1068209A1 (de) 2001-01-17
CN1153769C (zh) 2004-06-16
CN1294589A (zh) 2001-05-09
JP2002510691A (ja) 2002-04-09

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