DK174513B1 - Fremgangsmåde til fremstilling af bis-(3,5-dioxopiperazinyl)-alkaner eller -alkener - Google Patents

Fremgangsmåde til fremstilling af bis-(3,5-dioxopiperazinyl)-alkaner eller -alkener Download PDF

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Publication number
DK174513B1
DK174513B1 DK198900721A DK72189A DK174513B1 DK 174513 B1 DK174513 B1 DK 174513B1 DK 198900721 A DK198900721 A DK 198900721A DK 72189 A DK72189 A DK 72189A DK 174513 B1 DK174513 B1 DK 174513B1
Authority
DK
Denmark
Prior art keywords
formula
approx
process according
tetraamide
compound
Prior art date
Application number
DK198900721A
Other languages
Danish (da)
English (en)
Other versions
DK72189A (da
DK72189D0 (da
Inventor
Giampietro Borsotti
George W Clark
Chih-Yun Johnny Tu
Original Assignee
Erbamont Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erbamont Inc filed Critical Erbamont Inc
Publication of DK72189D0 publication Critical patent/DK72189D0/da
Publication of DK72189A publication Critical patent/DK72189A/da
Application granted granted Critical
Publication of DK174513B1 publication Critical patent/DK174513B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK198900721A 1988-02-17 1989-02-16 Fremgangsmåde til fremstilling af bis-(3,5-dioxopiperazinyl)-alkaner eller -alkener DK174513B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15719588 1988-02-17
US07/157,195 US4963679A (en) 1988-02-17 1988-02-17 Process for preparing bis (3,5-dioxopiperazinyl) alkanes or alkenes

Publications (3)

Publication Number Publication Date
DK72189D0 DK72189D0 (da) 1989-02-16
DK72189A DK72189A (da) 1989-08-18
DK174513B1 true DK174513B1 (da) 2003-05-05

Family

ID=22562711

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900721A DK174513B1 (da) 1988-02-17 1989-02-16 Fremgangsmåde til fremstilling af bis-(3,5-dioxopiperazinyl)-alkaner eller -alkener

Country Status (14)

Country Link
US (1) US4963679A (xx)
EP (1) EP0330381B1 (xx)
JP (1) JP2629038B2 (xx)
KR (1) KR970009041B1 (xx)
AT (1) ATE123027T1 (xx)
AU (1) AU611235B2 (xx)
CA (1) CA1303614C (xx)
DE (1) DE68922760T2 (xx)
DK (1) DK174513B1 (xx)
ES (1) ES2072295T3 (xx)
FI (1) FI97294C (xx)
HU (1) HU203326B (xx)
NO (1) NO168821C (xx)
ZA (1) ZA889452B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4764614A (en) * 1987-03-23 1988-08-16 Monsanto Company Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)
US5744455A (en) * 1988-01-27 1998-04-28 New York University Reduction of anthracycline-induced cardiotoxicity
WO1992000971A1 (en) * 1990-07-04 1992-01-23 Zenyaku Kogyo Kabushiki Kaisha Water-soluble bis-dioxopiperazine derivative
GB9122677D0 (en) * 1991-10-25 1991-12-11 Eurocetus Bv Process for preparing(s)(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)
TW482806B (en) * 1998-06-02 2002-04-11 Ciba Sc Holding Ag Compositions stabilized by dioxopiperazinyl derivatives
US6693100B1 (en) 1999-09-10 2004-02-17 Iervant Zarmanian Pharmaceutical compositions for treating psoriasis
HUP0202791A3 (en) * 1999-09-10 2003-02-28 Cyathus Exquirere Pharmaforsch Pharmaceutical compositions for treating psoriasis
AT504621B1 (de) 2006-11-24 2014-08-15 Cyathus Exquirere Pharmaforschungsgmbh Neues verfahren zur herstellung von 4,4'-(1-methyl -1,2-ethandiyl)-bis-(2,6-piperazindion)
CN101684100B (zh) * 2008-09-26 2011-11-16 重庆海腾制药有限公司 得拉唑沙或其可药用盐的制备方法
WO2012081036A2 (en) * 2010-12-13 2012-06-21 Sequent Scientific Limited A process for preparation of 4,4'-(1-methyl-1,2-ethandiyl)-bis-(2,6-piperazinedione)
CN110804022B (zh) * 2019-11-06 2023-01-17 扬子江药业集团有限公司 一种右丙亚胺的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2461519A (en) * 1948-03-17 1949-02-15 Frederick C Bersworth Method of producing carboxylic substituted aliphatic amines and metallic salts thereof
NL273692A (xx) * 1961-01-19 1900-01-01
US3941790A (en) * 1967-07-03 1976-03-02 National Research Development Corporation Bis diketopiperazines
GB1234935A (en) * 1967-07-03 1971-06-09 Nat Res Dev Piperazine derivatives
GB1374979A (en) * 1970-12-21 1974-11-20 Nat Res Dev 3,5-dioxopiperazine derivatives
GB1236947A (en) * 1968-08-15 1971-06-23 Ici Ltd Process for the preparation of piperazine derivatives
BE787766A (fr) * 1971-08-21 1973-02-19 Merck Patent Gmbh Imides d'acide glutarique et leur procede de preparation
US4704465A (en) * 1985-11-22 1987-11-03 Monsanto Company Process for preparing ethylenediaminetetraacetonitrile
US4764614A (en) * 1987-03-23 1988-08-16 Monsanto Company Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)

Also Published As

Publication number Publication date
FI97294B (fi) 1996-08-15
ATE123027T1 (de) 1995-06-15
AU611235B2 (en) 1991-06-06
US4963679A (en) 1990-10-16
EP0330381A1 (en) 1989-08-30
ES2072295T3 (es) 1995-07-16
EP0330381B1 (en) 1995-05-24
FI890760A0 (fi) 1989-02-16
DK72189A (da) 1989-08-18
KR890013000A (ko) 1989-09-20
FI97294C (fi) 1996-11-25
FI890760A (fi) 1989-08-18
DK72189D0 (da) 1989-02-16
HUT51260A (en) 1990-04-28
DE68922760D1 (de) 1995-06-29
JPH01228971A (ja) 1989-09-12
CA1303614C (en) 1992-06-16
DE68922760T2 (de) 1995-11-23
NO885415L (no) 1989-08-18
JP2629038B2 (ja) 1997-07-09
HU203326B (en) 1991-07-29
NO885415D0 (no) 1988-12-06
AU2656688A (en) 1989-08-17
NO168821C (no) 1992-04-08
KR970009041B1 (ko) 1997-06-03
ZA889452B (en) 1990-05-30
NO168821B (no) 1991-12-30

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