DE68922760D1 - Verfahren zur Herstellung von (3,5-Dioxopiperazinyl)-alkanen oder -alkenen. - Google Patents

Verfahren zur Herstellung von (3,5-Dioxopiperazinyl)-alkanen oder -alkenen.

Info

Publication number
DE68922760D1
DE68922760D1 DE68922760T DE68922760T DE68922760D1 DE 68922760 D1 DE68922760 D1 DE 68922760D1 DE 68922760 T DE68922760 T DE 68922760T DE 68922760 T DE68922760 T DE 68922760T DE 68922760 D1 DE68922760 D1 DE 68922760D1
Authority
DE
Germany
Prior art keywords
formula
chr1
chr2
tetranitrile
reacted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68922760T
Other languages
English (en)
Other versions
DE68922760T2 (de
Inventor
Chi-Yun Johnny Tu
George W Clark
Giampietro Borsotti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Erbamont Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erbamont Inc filed Critical Erbamont Inc
Publication of DE68922760D1 publication Critical patent/DE68922760D1/de
Application granted granted Critical
Publication of DE68922760T2 publication Critical patent/DE68922760T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE68922760T 1988-02-17 1989-02-17 Verfahren zur Herstellung von (3,5-Dioxopiperazinyl)-alkanen oder -alkenen. Expired - Lifetime DE68922760T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/157,195 US4963679A (en) 1988-02-17 1988-02-17 Process for preparing bis (3,5-dioxopiperazinyl) alkanes or alkenes

Publications (2)

Publication Number Publication Date
DE68922760D1 true DE68922760D1 (de) 1995-06-29
DE68922760T2 DE68922760T2 (de) 1995-11-23

Family

ID=22562711

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68922760T Expired - Lifetime DE68922760T2 (de) 1988-02-17 1989-02-17 Verfahren zur Herstellung von (3,5-Dioxopiperazinyl)-alkanen oder -alkenen.

Country Status (14)

Country Link
US (1) US4963679A (de)
EP (1) EP0330381B1 (de)
JP (1) JP2629038B2 (de)
KR (1) KR970009041B1 (de)
AT (1) ATE123027T1 (de)
AU (1) AU611235B2 (de)
CA (1) CA1303614C (de)
DE (1) DE68922760T2 (de)
DK (1) DK174513B1 (de)
ES (1) ES2072295T3 (de)
FI (1) FI97294C (de)
HU (1) HU203326B (de)
NO (1) NO168821C (de)
ZA (1) ZA889452B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4764614A (en) * 1987-03-23 1988-08-16 Monsanto Company Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)
US5744455A (en) * 1988-01-27 1998-04-28 New York University Reduction of anthracycline-induced cardiotoxicity
US5393889A (en) * 1990-07-04 1995-02-28 Zenyaku Kogyo Kabushiki Kaisha Water soluble bis-dioxopiperazine derivatives
GB9122677D0 (en) * 1991-10-25 1991-12-11 Eurocetus Bv Process for preparing(s)(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)
TW482806B (en) * 1998-06-02 2002-04-11 Ciba Sc Holding Ag Compositions stabilized by dioxopiperazinyl derivatives
WO2001019358A2 (en) * 1999-09-10 2001-03-22 Cyathus Exquirere Pharmaforschungs Gmbh Use dexrazoxane for treating psoriasis
YU17002A (sh) 1999-09-10 2004-11-25 Cyathus Exquirere Pharmaforschungs Gmbh. Upotreba deksrazoksana u lečenju psorijaze
AT504621B1 (de) * 2006-11-24 2014-08-15 Cyathus Exquirere Pharmaforschungsgmbh Neues verfahren zur herstellung von 4,4'-(1-methyl -1,2-ethandiyl)-bis-(2,6-piperazindion)
CN101684100B (zh) * 2008-09-26 2011-11-16 重庆海腾制药有限公司 得拉唑沙或其可药用盐的制备方法
WO2012081036A2 (en) * 2010-12-13 2012-06-21 Sequent Scientific Limited A process for preparation of 4,4'-(1-methyl-1,2-ethandiyl)-bis-(2,6-piperazinedione)
CN110804022B (zh) * 2019-11-06 2023-01-17 扬子江药业集团有限公司 一种右丙亚胺的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2461519A (en) * 1948-03-17 1949-02-15 Frederick C Bersworth Method of producing carboxylic substituted aliphatic amines and metallic salts thereof
NL273691A (de) * 1961-01-19 1900-01-01
US3941790A (en) * 1967-07-03 1976-03-02 National Research Development Corporation Bis diketopiperazines
GB1234935A (en) * 1967-07-03 1971-06-09 Nat Res Dev Piperazine derivatives
GB1374979A (en) * 1970-12-21 1974-11-20 Nat Res Dev 3,5-dioxopiperazine derivatives
GB1236947A (en) * 1968-08-15 1971-06-23 Ici Ltd Process for the preparation of piperazine derivatives
BE787766A (fr) * 1971-08-21 1973-02-19 Merck Patent Gmbh Imides d'acide glutarique et leur procede de preparation
US4704465A (en) * 1985-11-22 1987-11-03 Monsanto Company Process for preparing ethylenediaminetetraacetonitrile
US4764614A (en) * 1987-03-23 1988-08-16 Monsanto Company Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)

Also Published As

Publication number Publication date
AU611235B2 (en) 1991-06-06
NO885415D0 (no) 1988-12-06
ZA889452B (en) 1990-05-30
ATE123027T1 (de) 1995-06-15
EP0330381B1 (de) 1995-05-24
CA1303614C (en) 1992-06-16
FI97294B (fi) 1996-08-15
DK72189D0 (da) 1989-02-16
JP2629038B2 (ja) 1997-07-09
KR890013000A (ko) 1989-09-20
JPH01228971A (ja) 1989-09-12
HU203326B (en) 1991-07-29
KR970009041B1 (ko) 1997-06-03
FI890760A0 (fi) 1989-02-16
US4963679A (en) 1990-10-16
FI97294C (fi) 1996-11-25
NO885415L (no) 1989-08-18
EP0330381A1 (de) 1989-08-30
DK174513B1 (da) 2003-05-05
NO168821B (no) 1991-12-30
AU2656688A (en) 1989-08-17
DK72189A (da) 1989-08-18
HUT51260A (en) 1990-04-28
ES2072295T3 (es) 1995-07-16
DE68922760T2 (de) 1995-11-23
NO168821C (no) 1992-04-08
FI890760A (fi) 1989-08-18

Similar Documents

Publication Publication Date Title
DE3563848D1 (en) Process for the preparation of optically active alpha-arylalkanoic acids and intermediates thereof
DE68922760D1 (de) Verfahren zur Herstellung von (3,5-Dioxopiperazinyl)-alkanen oder -alkenen.
DE58900982D1 (de) Verfahren zur herstellung von alpha, beta -ungesaettigten ketonen.
DE69802388D1 (de) Verfahren zur herstellung von nicotinsäuren
DE69605873D1 (de) Verfahren zur Herstellung von Isothiocyanat-Derivaten
DE59707269D1 (de) Verfahren zur Herstellung von Z-L-Asparaginsäure-Dinatriumsalz aus Fumarsäure
DE69410073D1 (de) Verfahren zur Herstellung von 2-Perfluoroalkyl-3-oxazolin-5-one
DE69821763D1 (de) Verfahren zur herstellung von 2-alkylthio-substituierten benzoesäurederivaten
DK501188A (da) Fremgangsmaade til fremstilling af aliphatylphosphinsyrederivater
TW370520B (en) A process for the preparation of NG-monomethyl-L-arginine hydrochloride
DE69418802D1 (de) Verfahren zur Herstellung von N-Alkylacetamiden
DE69407742D1 (de) Verfahren zur herstellung von alpha-alkoxy-iminophenylacetonitril
TH23419A (th) การทำปฏิกิริยาของวัสดุคาร์บอนกับเกลือไดเอโซเนียมและผลผลิตของคาร์บอนที่ได้รับ
TH13999A (th) วิธีการเตรียมอนุพันธ์ต่าง ๆ ของไฟโซสทิกมีน คาร์บาเมท จากอีเซอรีโธล
TH8283B (th) การทำปฏิกิริยาของวัสดุคาร์บอนกับเกลือไดเอโซเนียมและผลผลิตของคาร์บอนที่ได้รับ
ATE47712T1 (de) Verfahren zur herstellung einer pyridylpropansaeure.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition