DE68922760D1 - Verfahren zur Herstellung von (3,5-Dioxopiperazinyl)-alkanen oder -alkenen. - Google Patents
Verfahren zur Herstellung von (3,5-Dioxopiperazinyl)-alkanen oder -alkenen.Info
- Publication number
- DE68922760D1 DE68922760D1 DE68922760T DE68922760T DE68922760D1 DE 68922760 D1 DE68922760 D1 DE 68922760D1 DE 68922760 T DE68922760 T DE 68922760T DE 68922760 T DE68922760 T DE 68922760T DE 68922760 D1 DE68922760 D1 DE 68922760D1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- chr1
- chr2
- tetranitrile
- reacted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/157,195 US4963679A (en) | 1988-02-17 | 1988-02-17 | Process for preparing bis (3,5-dioxopiperazinyl) alkanes or alkenes |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68922760D1 true DE68922760D1 (de) | 1995-06-29 |
DE68922760T2 DE68922760T2 (de) | 1995-11-23 |
Family
ID=22562711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68922760T Expired - Lifetime DE68922760T2 (de) | 1988-02-17 | 1989-02-17 | Verfahren zur Herstellung von (3,5-Dioxopiperazinyl)-alkanen oder -alkenen. |
Country Status (14)
Country | Link |
---|---|
US (1) | US4963679A (de) |
EP (1) | EP0330381B1 (de) |
JP (1) | JP2629038B2 (de) |
KR (1) | KR970009041B1 (de) |
AT (1) | ATE123027T1 (de) |
AU (1) | AU611235B2 (de) |
CA (1) | CA1303614C (de) |
DE (1) | DE68922760T2 (de) |
DK (1) | DK174513B1 (de) |
ES (1) | ES2072295T3 (de) |
FI (1) | FI97294C (de) |
HU (1) | HU203326B (de) |
NO (1) | NO168821C (de) |
ZA (1) | ZA889452B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4764614A (en) * | 1987-03-23 | 1988-08-16 | Monsanto Company | Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione) |
US5744455A (en) * | 1988-01-27 | 1998-04-28 | New York University | Reduction of anthracycline-induced cardiotoxicity |
US5393889A (en) * | 1990-07-04 | 1995-02-28 | Zenyaku Kogyo Kabushiki Kaisha | Water soluble bis-dioxopiperazine derivatives |
GB9122677D0 (en) * | 1991-10-25 | 1991-12-11 | Eurocetus Bv | Process for preparing(s)(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione) |
TW482806B (en) * | 1998-06-02 | 2002-04-11 | Ciba Sc Holding Ag | Compositions stabilized by dioxopiperazinyl derivatives |
WO2001019358A2 (en) * | 1999-09-10 | 2001-03-22 | Cyathus Exquirere Pharmaforschungs Gmbh | Use dexrazoxane for treating psoriasis |
YU17002A (sh) | 1999-09-10 | 2004-11-25 | Cyathus Exquirere Pharmaforschungs Gmbh. | Upotreba deksrazoksana u lečenju psorijaze |
AT504621B1 (de) * | 2006-11-24 | 2014-08-15 | Cyathus Exquirere Pharmaforschungsgmbh | Neues verfahren zur herstellung von 4,4'-(1-methyl -1,2-ethandiyl)-bis-(2,6-piperazindion) |
CN101684100B (zh) * | 2008-09-26 | 2011-11-16 | 重庆海腾制药有限公司 | 得拉唑沙或其可药用盐的制备方法 |
WO2012081036A2 (en) * | 2010-12-13 | 2012-06-21 | Sequent Scientific Limited | A process for preparation of 4,4'-(1-methyl-1,2-ethandiyl)-bis-(2,6-piperazinedione) |
CN110804022B (zh) * | 2019-11-06 | 2023-01-17 | 扬子江药业集团有限公司 | 一种右丙亚胺的制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2461519A (en) * | 1948-03-17 | 1949-02-15 | Frederick C Bersworth | Method of producing carboxylic substituted aliphatic amines and metallic salts thereof |
NL273691A (de) * | 1961-01-19 | 1900-01-01 | ||
US3941790A (en) * | 1967-07-03 | 1976-03-02 | National Research Development Corporation | Bis diketopiperazines |
GB1234935A (en) * | 1967-07-03 | 1971-06-09 | Nat Res Dev | Piperazine derivatives |
GB1374979A (en) * | 1970-12-21 | 1974-11-20 | Nat Res Dev | 3,5-dioxopiperazine derivatives |
GB1236947A (en) * | 1968-08-15 | 1971-06-23 | Ici Ltd | Process for the preparation of piperazine derivatives |
BE787766A (fr) * | 1971-08-21 | 1973-02-19 | Merck Patent Gmbh | Imides d'acide glutarique et leur procede de preparation |
US4704465A (en) * | 1985-11-22 | 1987-11-03 | Monsanto Company | Process for preparing ethylenediaminetetraacetonitrile |
US4764614A (en) * | 1987-03-23 | 1988-08-16 | Monsanto Company | Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione) |
-
1988
- 1988-02-17 US US07/157,195 patent/US4963679A/en not_active Expired - Lifetime
- 1988-12-06 AU AU26566/88A patent/AU611235B2/en not_active Expired
- 1988-12-06 NO NO885415A patent/NO168821C/no unknown
- 1988-12-09 CA CA000585525A patent/CA1303614C/en not_active Expired - Fee Related
- 1988-12-19 ZA ZA889452A patent/ZA889452B/xx unknown
-
1989
- 1989-01-20 JP JP1011797A patent/JP2629038B2/ja not_active Expired - Lifetime
- 1989-02-16 DK DK198900721A patent/DK174513B1/da not_active IP Right Cessation
- 1989-02-16 FI FI890760A patent/FI97294C/fi not_active IP Right Cessation
- 1989-02-16 HU HU89783A patent/HU203326B/hu unknown
- 1989-02-16 KR KR1019890001768A patent/KR970009041B1/ko not_active IP Right Cessation
- 1989-02-17 ES ES89301540T patent/ES2072295T3/es not_active Expired - Lifetime
- 1989-02-17 EP EP89301540A patent/EP0330381B1/de not_active Expired - Lifetime
- 1989-02-17 AT AT89301540T patent/ATE123027T1/de not_active IP Right Cessation
- 1989-02-17 DE DE68922760T patent/DE68922760T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU611235B2 (en) | 1991-06-06 |
NO885415D0 (no) | 1988-12-06 |
ZA889452B (en) | 1990-05-30 |
ATE123027T1 (de) | 1995-06-15 |
EP0330381B1 (de) | 1995-05-24 |
CA1303614C (en) | 1992-06-16 |
FI97294B (fi) | 1996-08-15 |
DK72189D0 (da) | 1989-02-16 |
JP2629038B2 (ja) | 1997-07-09 |
KR890013000A (ko) | 1989-09-20 |
JPH01228971A (ja) | 1989-09-12 |
HU203326B (en) | 1991-07-29 |
KR970009041B1 (ko) | 1997-06-03 |
FI890760A0 (fi) | 1989-02-16 |
US4963679A (en) | 1990-10-16 |
FI97294C (fi) | 1996-11-25 |
NO885415L (no) | 1989-08-18 |
EP0330381A1 (de) | 1989-08-30 |
DK174513B1 (da) | 2003-05-05 |
NO168821B (no) | 1991-12-30 |
AU2656688A (en) | 1989-08-17 |
DK72189A (da) | 1989-08-18 |
HUT51260A (en) | 1990-04-28 |
ES2072295T3 (es) | 1995-07-16 |
DE68922760T2 (de) | 1995-11-23 |
NO168821C (no) | 1992-04-08 |
FI890760A (fi) | 1989-08-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |