DK173937B1 - Antitumor aktive epoxyforbindelser, fremgangsmåde til fremstilling heraf, biologisk ren mikroorganismekultur til brug derved, farmaceutisk præparat omfattende disse forbindelser og anvendelse af forbindelserne - Google Patents
Antitumor aktive epoxyforbindelser, fremgangsmåde til fremstilling heraf, biologisk ren mikroorganismekultur til brug derved, farmaceutisk præparat omfattende disse forbindelser og anvendelse af forbindelserne Download PDFInfo
- Publication number
- DK173937B1 DK173937B1 DK198901071A DK107189A DK173937B1 DK 173937 B1 DK173937 B1 DK 173937B1 DK 198901071 A DK198901071 A DK 198901071A DK 107189 A DK107189 A DK 107189A DK 173937 B1 DK173937 B1 DK 173937B1
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- dihydro
- pharmaceutical composition
- tumor
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/55—Streptomyces hygroscopicus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Epoxy Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/165,337 US4912133A (en) | 1988-03-07 | 1988-03-07 | BU-3862T antitumor antibiotic |
| US16533788 | 1988-03-07 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK107189D0 DK107189D0 (da) | 1989-03-06 |
| DK107189A DK107189A (da) | 1989-09-08 |
| DK173937B1 true DK173937B1 (da) | 2002-02-25 |
Family
ID=22598495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198901071A DK173937B1 (da) | 1988-03-07 | 1989-03-06 | Antitumor aktive epoxyforbindelser, fremgangsmåde til fremstilling heraf, biologisk ren mikroorganismekultur til brug derved, farmaceutisk præparat omfattende disse forbindelser og anvendelse af forbindelserne |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4912133A (de) |
| EP (1) | EP0332080B1 (de) |
| JP (1) | JP2821756B2 (de) |
| KR (1) | KR960016206B1 (de) |
| AT (1) | ATE76406T1 (de) |
| AU (1) | AU618790B2 (de) |
| CA (1) | CA1338184C (de) |
| DE (1) | DE68901552D1 (de) |
| DK (1) | DK173937B1 (de) |
| ES (1) | ES2036729T3 (de) |
| FI (1) | FI90991C (de) |
| GR (1) | GR3004756T3 (de) |
| IE (1) | IE62211B1 (de) |
| IL (1) | IL89477A (de) |
| NO (1) | NO174432C (de) |
| PT (1) | PT89917B (de) |
| ZA (1) | ZA891695B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5071957A (en) * | 1989-08-04 | 1991-12-10 | Bristol-Myers Company | Antibiotic BU-4061T |
| US7524883B2 (en) | 2002-01-08 | 2009-04-28 | Eisai R&D Management Co., Ltd. | Eponemycin and epoxomicin analogs and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4474800A (en) * | 1980-05-13 | 1984-10-02 | Taisho Pharmaceutical Co., Ltd. | Epoxysuccinyl amino acid derivatives |
| JPS5865287A (ja) * | 1981-10-14 | 1983-04-18 | Nippon Chemiphar Co Ltd | ベーターアミノアルコール誘導体と，心筋梗塞の予防および治療剤 |
| JPS58116412A (ja) * | 1981-12-29 | 1983-07-11 | Taisho Pharmaceut Co Ltd | 直腸投与製剤 |
| JPS608223A (ja) * | 1983-06-28 | 1985-01-17 | Taisho Pharmaceut Co Ltd | 抗アレルギ−剤 |
-
1988
- 1988-03-07 US US07/165,337 patent/US4912133A/en not_active Expired - Lifetime
-
1989
- 1989-03-02 FI FI891001A patent/FI90991C/fi not_active IP Right Cessation
- 1989-03-03 DE DE8989103764T patent/DE68901552D1/de not_active Expired - Lifetime
- 1989-03-03 CA CA000592703A patent/CA1338184C/en not_active Expired - Lifetime
- 1989-03-03 AT AT89103764T patent/ATE76406T1/de not_active IP Right Cessation
- 1989-03-03 EP EP89103764A patent/EP0332080B1/de not_active Expired - Lifetime
- 1989-03-03 ES ES198989103764T patent/ES2036729T3/es not_active Expired - Lifetime
- 1989-03-03 IL IL8947789A patent/IL89477A/en unknown
- 1989-03-06 IE IE72489A patent/IE62211B1/en not_active IP Right Cessation
- 1989-03-06 AU AU31041/89A patent/AU618790B2/en not_active Expired
- 1989-03-06 DK DK198901071A patent/DK173937B1/da not_active IP Right Cessation
- 1989-03-06 NO NO890944A patent/NO174432C/no not_active IP Right Cessation
- 1989-03-06 ZA ZA891695A patent/ZA891695B/xx unknown
- 1989-03-06 PT PT89917A patent/PT89917B/pt not_active IP Right Cessation
- 1989-03-07 KR KR1019890002806A patent/KR960016206B1/ko not_active IP Right Cessation
- 1989-03-07 JP JP1053081A patent/JP2821756B2/ja not_active Expired - Lifetime
-
1992
- 1992-05-29 GR GR920400556T patent/GR3004756T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE890724L (en) | 1989-09-07 |
| PT89917A (pt) | 1989-11-10 |
| AU618790B2 (en) | 1992-01-09 |
| EP0332080B1 (de) | 1992-05-20 |
| NO890944D0 (no) | 1989-03-06 |
| EP0332080A1 (de) | 1989-09-13 |
| DE68901552D1 (de) | 1992-06-25 |
| IL89477A (en) | 1994-11-28 |
| US4912133A (en) | 1990-03-27 |
| JP2821756B2 (ja) | 1998-11-05 |
| ES2036729T3 (es) | 1993-06-01 |
| FI90991B (fi) | 1994-01-14 |
| FI90991C (fi) | 1994-04-25 |
| NO174432C (no) | 1998-06-09 |
| ZA891695B (en) | 1989-11-29 |
| KR890014102A (ko) | 1989-10-21 |
| CA1338184C (en) | 1996-03-26 |
| ATE76406T1 (de) | 1992-06-15 |
| FI891001A (fi) | 1989-09-08 |
| PT89917B (pt) | 1994-05-31 |
| JPH0272167A (ja) | 1990-03-12 |
| DK107189A (da) | 1989-09-08 |
| FI891001A0 (fi) | 1989-03-02 |
| KR960016206B1 (ko) | 1996-12-06 |
| IE62211B1 (en) | 1995-01-11 |
| GR3004756T3 (de) | 1993-04-28 |
| AU3104189A (en) | 1989-09-07 |
| NO174432B (no) | 1994-01-24 |
| DK107189D0 (da) | 1989-03-06 |
| NO890944L (no) | 1989-09-08 |
| IL89477A0 (en) | 1989-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |