DK173317B1 - Stabiliseret præparat af anthracyclinderivat samt fremgangsmåde til fremstilling af dette - Google Patents

Stabiliseret præparat af anthracyclinderivat samt fremgangsmåde til fremstilling af dette Download PDF

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Publication number
DK173317B1
DK173317B1 DK198804366A DK436688A DK173317B1 DK 173317 B1 DK173317 B1 DK 173317B1 DK 198804366 A DK198804366 A DK 198804366A DK 436688 A DK436688 A DK 436688A DK 173317 B1 DK173317 B1 DK 173317B1
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DK
Denmark
Prior art keywords
salt
cysteine
preparation
naphthacene
deoxy
Prior art date
Application number
DK198804366A
Other languages
Danish (da)
English (en)
Other versions
DK436688D0 (da
DK436688A (da
Inventor
Yasuhisa Sakamaki
Yukio Ozaki
Norihiko Tanno
Original Assignee
Sumitomo Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharma filed Critical Sumitomo Pharma
Publication of DK436688D0 publication Critical patent/DK436688D0/da
Publication of DK436688A publication Critical patent/DK436688A/da
Application granted granted Critical
Publication of DK173317B1 publication Critical patent/DK173317B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK198804366A 1987-08-05 1988-08-04 Stabiliseret præparat af anthracyclinderivat samt fremgangsmåde til fremstilling af dette DK173317B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19703287 1987-08-05
JP62197032A JP2603480B2 (ja) 1987-08-05 1987-08-05 安定化されたアンスラサイクリン系製剤

Publications (3)

Publication Number Publication Date
DK436688D0 DK436688D0 (da) 1988-08-04
DK436688A DK436688A (da) 1989-02-06
DK173317B1 true DK173317B1 (da) 2000-07-17

Family

ID=16367605

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198804366A DK173317B1 (da) 1987-08-05 1988-08-04 Stabiliseret præparat af anthracyclinderivat samt fremgangsmåde til fremstilling af dette

Country Status (14)

Country Link
US (1) US4952566A (de)
EP (1) EP0302729B1 (de)
JP (1) JP2603480B2 (de)
KR (1) KR970000507B1 (de)
AT (1) ATE71526T1 (de)
AU (1) AU609168B2 (de)
CA (1) CA1324959C (de)
DE (1) DE3867751D1 (de)
DK (1) DK173317B1 (de)
ES (1) ES2038763T3 (de)
FI (1) FI91483C (de)
GR (1) GR3004330T3 (de)
NO (1) NO175134C (de)
NZ (1) NZ225654A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222489B1 (hu) * 1990-07-25 2003-07-28 Novartis Ag. Stabilizált gyógyszerkészítmények és eljárás az előállításukra
US6300361B1 (en) 1990-07-25 2001-10-09 Novartis Ag Stabilized pharmaceutical compositions comprising acid donors
FR2665834B1 (fr) * 1991-07-24 2001-02-23 Sandoz Sa Composition pharmaceutique stabilisee par un donneur d'acide chlorhydrique, et sa preparation.
DE19741715A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Pentopyranosyl-Nucleosid, seine Herstellung und Verwendung
DK1034181T3 (da) * 1997-11-28 2006-03-20 Dainippon Sumitomo Pharma Co Krystallinsk amrubicinhydrochlorid
EP1439185A4 (de) 2001-10-23 2009-08-19 Sumitomo Chemical Co Stabilisierung von amrubicin-hydrochlorid
CN1741804A (zh) * 2002-11-29 2006-03-01 住友制药株式会社 稳定的蒽环类化合物的冻干制剂
CN100395255C (zh) * 2005-02-02 2008-06-18 江苏豪森药业股份有限公司 马来酸氨柔比星盐及其制备方法和用途
CA2606390A1 (en) * 2005-05-11 2006-11-16 Sicor, Inc. Stable lyophilized anthracycline glycosides
JP5389910B2 (ja) * 2009-05-27 2014-01-15 大日本住友製薬株式会社 アンスラサイクリン系化合物の安定な凍結乾燥製剤
EP2934451B1 (de) * 2012-12-19 2017-01-04 Colgate-Palmolive Company Zweikomponentige zusammensetzungen mit zinkaminosäure-halidkomplexen und cystein
WO2016024369A1 (ja) * 2014-08-13 2016-02-18 テバ製薬株式会社 がん治療用医薬組成物
WO2019094819A2 (en) * 2017-11-09 2019-05-16 Abon Pharmaceuticals, Llc Intravenous delivery systems for chemotherapy drugs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2522187C2 (de) * 1975-05-17 1977-10-28 Byk Gulden Lomberg Chem Fab Verwendung von Cystein oder dessen Säureadditionssalz und Natriumdisulfit zur Stabilisierung von injizierbaren, einen pH-Wert zwischen 7 und 9 aufweisenden, Vitamin B tief 12 und nichtsteroidal Entzündungshemmer enthaltenden Arzneimitteln
US4540695A (en) * 1981-08-12 1985-09-10 Sumitomo Chemical Co., Ltd. Aminonaphthacene derivatives and their use
JPS5976099A (ja) * 1982-10-22 1984-04-28 Sumitomo Chem Co Ltd アミノナフタセン誘導体とその製造方法
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions

Also Published As

Publication number Publication date
CA1324959C (en) 1993-12-07
NO175134C (no) 1994-09-07
AU609168B2 (en) 1991-04-26
AU2042188A (en) 1989-02-09
ATE71526T1 (de) 1992-02-15
JPS6440493A (en) 1989-02-10
FI883602A (fi) 1989-02-06
US4952566A (en) 1990-08-28
FI91483B (fi) 1994-03-31
EP0302729A1 (de) 1989-02-08
DE3867751D1 (de) 1992-02-27
DK436688D0 (da) 1988-08-04
GR3004330T3 (de) 1993-03-31
KR890003791A (ko) 1989-04-18
EP0302729B1 (de) 1992-01-15
FI91483C (fi) 1994-07-11
DK436688A (da) 1989-02-06
NO883447D0 (no) 1988-08-03
FI883602A0 (fi) 1988-08-01
JP2603480B2 (ja) 1997-04-23
NO175134B (no) 1994-05-30
ES2038763T3 (es) 1993-08-01
NO883447L (no) 1989-02-06
KR970000507B1 (ko) 1997-01-13
NZ225654A (en) 1991-03-26

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired