DK1696931T3 - Amino-substituerede diaryl[A,D]cyclohepten-analoger som muskarinske agonister og fremgangsmåder til behandling af neuropsykiatriske sygdomme - Google Patents
Amino-substituerede diaryl[A,D]cyclohepten-analoger som muskarinske agonister og fremgangsmåder til behandling af neuropsykiatriske sygdommeInfo
- Publication number
- DK1696931T3 DK1696931T3 DK04815318T DK04815318T DK1696931T3 DK 1696931 T3 DK1696931 T3 DK 1696931T3 DK 04815318 T DK04815318 T DK 04815318T DK 04815318 T DK04815318 T DK 04815318T DK 1696931 T3 DK1696931 T3 DK 1696931T3
- Authority
- DK
- Denmark
- Prior art keywords
- analogs
- methods
- amino
- cyclohepten
- treatment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53192703P | 2003-12-22 | 2003-12-22 | |
US54809004P | 2004-02-24 | 2004-02-24 | |
US54860404P | 2004-02-27 | 2004-02-27 | |
PCT/US2004/043224 WO2005063254A2 (fr) | 2003-12-22 | 2004-12-21 | Analogues de diaryl[a,d]cycloheptene amino substitues utilises comme agonistes muscariniques, et procedes de traitement de troubles neuropsychiatriques |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1696931T3 true DK1696931T3 (da) | 2009-06-29 |
Family
ID=34743692
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04815318T DK1696931T3 (da) | 2003-12-22 | 2004-12-21 | Amino-substituerede diaryl[A,D]cyclohepten-analoger som muskarinske agonister og fremgangsmåder til behandling af neuropsykiatriske sygdomme |
Country Status (23)
Country | Link |
---|---|
US (5) | US7550454B2 (fr) |
EP (2) | EP1696931B1 (fr) |
JP (1) | JP2007534656A (fr) |
KR (1) | KR101157881B1 (fr) |
CN (1) | CN101962369A (fr) |
AT (1) | ATE426405T1 (fr) |
AU (1) | AU2004308955B2 (fr) |
BR (1) | BRPI0417749A (fr) |
CA (1) | CA2550735A1 (fr) |
CY (1) | CY1109171T1 (fr) |
DE (1) | DE602004020263D1 (fr) |
DK (1) | DK1696931T3 (fr) |
ES (1) | ES2324713T3 (fr) |
HK (1) | HK1095092A1 (fr) |
IL (1) | IL176447A0 (fr) |
MX (1) | MXPA06007244A (fr) |
NO (1) | NO20063371L (fr) |
NZ (1) | NZ547911A (fr) |
PL (1) | PL1696931T3 (fr) |
PT (1) | PT1696931E (fr) |
SG (1) | SG133606A1 (fr) |
SI (1) | SI1696931T1 (fr) |
WO (1) | WO2005063254A2 (fr) |
Families Citing this family (88)
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IL151164A0 (en) | 2000-03-06 | 2003-04-10 | Acadia Pharm Inc | Azacyclic compounds for use in the treatment of serotonin related diseases |
KR20100008799A (ko) | 2001-12-28 | 2010-01-26 | 아카디아 파마슈티칼스 인코포레이티드 | 모노아민 수용체 조정자로서의 스피로아자사이클릭 화합물 |
IL164155A0 (en) * | 2002-03-20 | 2005-12-18 | Teva Pharma | Crystalline forms of quetiapine hemifumarate |
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US7253186B2 (en) | 2002-06-24 | 2007-08-07 | Carl-Magnus Andersson | N-substituted piperidine derivatives as serotonin receptor agents |
US7538222B2 (en) | 2002-06-24 | 2009-05-26 | Acadia Pharmaceuticals, Inc. | N-substituted piperidine derivatives as serotonin receptor agents |
CA2512639C (fr) | 2003-01-16 | 2012-10-30 | Acadia Pharmaceuticals Inc. | Agonistes inverses selectifs pour le recepteur de la serotonine 2a/2c utilises comme agents therapeutiques contre les maladies neurodegeneratives |
US20050085463A1 (en) * | 2003-01-23 | 2005-04-21 | Weiner David M. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
US20050250767A1 (en) * | 2003-01-23 | 2005-11-10 | Weiner David M | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
WO2004064753A2 (fr) * | 2003-01-23 | 2004-08-05 | Acadia Pharmaceuticals Inc | Utilisation de la n-desmethylclozapine pour le traitement de maladies neuropsychiatriques chez l'homme |
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WO2008021463A2 (fr) * | 2006-08-15 | 2008-02-21 | Acadia Pharmaceuticals, Inc. | Analogues de diaryl[a,d]cycloheptène à substitution amino, utilisés comme agonistes muscariniques et méthodes de traitement de troubles neuropsychiatriques |
SI1696931T1 (sl) * | 2003-12-22 | 2009-08-31 | Acadia Pharm Inc | Amino substituirani diaril(a,d)cikloheptenski analogi kot muskarinski agonisti in postopki za zdravljenje nevropsihiatričnih motenj |
US20050171088A1 (en) * | 2004-01-30 | 2005-08-04 | Astrazeneca Ab | Treatment of psychoses with dibenzothiazepine antipsychotic |
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US20050261278A1 (en) * | 2004-05-21 | 2005-11-24 | Weiner David M | Selective serotonin receptor inverse agonists as therapeutics for disease |
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CA3154630A1 (fr) | 2019-10-21 | 2021-04-29 | Mark E. Duggan | Derives de l'acide 3-(4-(11h-dibenzo[b,e][1,4]azepin-6-yl)piperazin-1-yl)- et 3-(4-(dibenzo[b,f][1,4]oxazepin/thiazepin/diazepin-11-yl)piperazin-1-yl)-propanoique utilises comme modulateurs des recepteurs h1 et 5-ht2a pour le traitement des troubles du sommei |
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-
2004
- 2004-12-21 SI SI200431143T patent/SI1696931T1/sl unknown
- 2004-12-21 PL PL04815318T patent/PL1696931T3/pl unknown
- 2004-12-21 CN CN2010102389158A patent/CN101962369A/zh active Pending
- 2004-12-21 DE DE602004020263T patent/DE602004020263D1/de active Active
- 2004-12-21 DK DK04815318T patent/DK1696931T3/da active
- 2004-12-21 EP EP04815318A patent/EP1696931B1/fr not_active Not-in-force
- 2004-12-21 SG SG200704645-1A patent/SG133606A1/en unknown
- 2004-12-21 ES ES04815318T patent/ES2324713T3/es active Active
- 2004-12-21 PT PT04815318T patent/PT1696931E/pt unknown
- 2004-12-21 MX MXPA06007244A patent/MXPA06007244A/es active IP Right Grant
- 2004-12-21 EP EP09155868A patent/EP2088147A1/fr not_active Withdrawn
- 2004-12-21 CA CA002550735A patent/CA2550735A1/fr not_active Abandoned
- 2004-12-21 BR BRPI0417749-5A patent/BRPI0417749A/pt not_active IP Right Cessation
- 2004-12-21 NZ NZ547911A patent/NZ547911A/en not_active IP Right Cessation
- 2004-12-21 WO PCT/US2004/043224 patent/WO2005063254A2/fr active Application Filing
- 2004-12-21 KR KR1020067014864A patent/KR101157881B1/ko not_active IP Right Cessation
- 2004-12-21 AU AU2004308955A patent/AU2004308955B2/en not_active Ceased
- 2004-12-21 JP JP2006547344A patent/JP2007534656A/ja not_active Withdrawn
- 2004-12-21 US US11/019,555 patent/US7550454B2/en not_active Expired - Fee Related
- 2004-12-21 AT AT04815318T patent/ATE426405T1/de active
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2006
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- 2006-05-03 US US11/417,441 patent/US7491715B2/en not_active Expired - Fee Related
- 2006-06-20 IL IL176447A patent/IL176447A0/en unknown
- 2006-07-20 NO NO20063371A patent/NO20063371L/no not_active Application Discontinuation
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2007
- 2007-03-05 HK HK07102395.0A patent/HK1095092A1/xx not_active IP Right Cessation
- 2007-04-10 US US11/733,476 patent/US7622461B2/en not_active Expired - Fee Related
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2009
- 2009-06-25 CY CY20091100666T patent/CY1109171T1/el unknown
- 2009-11-18 US US12/621,435 patent/US20100129473A1/en not_active Abandoned
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