DK1691824T3 - Proteiner tilhörende BCL-2-familien og fragmenter deraf og deres anvendelse i cancerpatienter - Google Patents
Proteiner tilhörende BCL-2-familien og fragmenter deraf og deres anvendelse i cancerpatienterInfo
- Publication number
- DK1691824T3 DK1691824T3 DK04797460T DK04797460T DK1691824T3 DK 1691824 T3 DK1691824 T3 DK 1691824T3 DK 04797460 T DK04797460 T DK 04797460T DK 04797460 T DK04797460 T DK 04797460T DK 1691824 T3 DK1691824 T3 DK 1691824T3
- Authority
- DK
- Denmark
- Prior art keywords
- fragments
- bcl
- family
- cancer patients
- proteins belonging
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 102000051485 Bcl-2 family Human genes 0.000 title abstract 2
- 108700038897 Bcl-2 family Proteins 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 title abstract 2
- 102000007079 Peptide Fragments Human genes 0.000 abstract 2
- 108010033276 Peptide Fragments Proteins 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 108091008874 T cell receptors Proteins 0.000 abstract 1
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52311903P | 2003-11-19 | 2003-11-19 | |
| DKPA200301716 | 2003-11-19 | ||
| PCT/DK2004/000799 WO2005049073A2 (en) | 2003-11-19 | 2004-11-18 | Proteins belonging to the bcl-2 family and fragments thereof, and their use in cancer patients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1691824T3 true DK1691824T3 (da) | 2009-07-06 |
Family
ID=39149116
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09154734.9T DK2087904T3 (da) | 2003-11-19 | 2004-11-18 | Terapeutisk anvendelse af peptider stammende fra Bcl-XL-protein i cancerpatienter |
| DK04797460T DK1691824T3 (da) | 2003-11-19 | 2004-11-18 | Proteiner tilhörende BCL-2-familien og fragmenter deraf og deres anvendelse i cancerpatienter |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09154734.9T DK2087904T3 (da) | 2003-11-19 | 2004-11-18 | Terapeutisk anvendelse af peptider stammende fra Bcl-XL-protein i cancerpatienter |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7842294B2 (ru) |
| EP (2) | EP2087904B1 (ru) |
| JP (2) | JP4926714B2 (ru) |
| KR (2) | KR101216655B1 (ru) |
| CN (1) | CN1921878B (ru) |
| AT (1) | ATE424842T1 (ru) |
| AU (1) | AU2004290866B2 (ru) |
| CA (1) | CA2546794C (ru) |
| DE (1) | DE602004019965D1 (ru) |
| DK (2) | DK2087904T3 (ru) |
| ES (2) | ES2436429T3 (ru) |
| HK (1) | HK1101131A1 (ru) |
| MX (1) | MXPA06005738A (ru) |
| PL (2) | PL1691824T3 (ru) |
| PT (1) | PT1691824E (ru) |
| RU (1) | RU2367468C2 (ru) |
| WO (1) | WO2005049073A2 (ru) |
| ZA (1) | ZA200604866B (ru) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009003492A1 (en) | 2007-07-03 | 2009-01-08 | Dako Denmark A/S | Mhc multimers, methods for their generation, labeling and use |
| US7892559B2 (en) * | 2002-01-30 | 2011-02-22 | Survac Aps | Survivin-derived peptides and use thereof |
| PT2359841E (pt) * | 2003-01-30 | 2015-02-10 | Survac Aps | Péptidos derivados de survivina e a sua utilização |
| US20130052215A9 (en) * | 2003-09-26 | 2013-02-28 | Eckhard Podack | Tumor vaccine |
| US7612162B2 (en) | 2004-09-21 | 2009-11-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Peptide analogs capable of enhancing stimulation of a glioma-specific CTL response |
| CN101438437A (zh) * | 2004-10-19 | 2009-05-20 | 麻省理工学院 | 用于自组装、柔软和轻的锂电池组的病毒支架 |
| CN103169958A (zh) * | 2005-02-04 | 2013-06-26 | 萨瓦克公司 | 存活蛋白肽疫苗 |
| AU2011203535B2 (en) * | 2005-02-04 | 2012-10-11 | Survac Aps | Survivin peptide vaccine |
| EP1934250A2 (en) * | 2005-09-09 | 2008-06-25 | Government of the United States of America, as represented by the Secretary, Department of Health and Human Services | Methods and compositions for inhibiting cell death or enhancing cell proliferation |
| EP2361930A3 (en) * | 2007-03-26 | 2011-10-26 | Dako Denmark A/S | Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases |
| US10611818B2 (en) | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
| WO2009106073A2 (en) * | 2008-02-28 | 2009-09-03 | Dako Denmark A/S | Mhc multimers in borrelia diagnostics and disease |
| US10968269B1 (en) | 2008-02-28 | 2021-04-06 | Agilent Technologies, Inc. | MHC multimers in borrelia diagnostics and disease |
| CA2723114C (en) | 2008-05-16 | 2018-02-27 | Taiga Biotechnologies, Inc. | Antibodies and processes for preparing the same |
| US20100093623A1 (en) * | 2008-07-16 | 2010-04-15 | Burnham Institute For Medical Research | Compositions and methods for modulating nod-like receptor activity and uses thereof |
| WO2010009735A2 (en) | 2008-07-23 | 2010-01-28 | Dako Denmark A/S | Combinatorial analysis and repair |
| WO2010025421A2 (en) | 2008-08-28 | 2010-03-04 | Taiga Biotechnologies, Inc. | Modulators of myc, methods of using the same, and methods of identifying agents that modulate myc |
| GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| WO2010037397A1 (en) * | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cmv immune monitoring |
| EP2337795A2 (en) * | 2008-10-01 | 2011-06-29 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
| US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
| WO2010037402A1 (en) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| EP2491116A4 (en) * | 2009-10-22 | 2013-12-11 | Univ Jefferson | CELL-BASED ANTI-RISK COMPOSITIONS AND METHOD FOR THEIR PREPARATION AND USE |
| AU2011225577B2 (en) | 2010-03-11 | 2017-01-19 | Oncotherapy Science, Inc. | HJURP peptides and vaccines including the same |
| EP3511013B1 (en) | 2010-08-24 | 2022-09-07 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Interleukin-13 receptor alpha 2 peptide-based brain cancer vaccines |
| HUE056350T2 (hu) | 2012-05-16 | 2022-02-28 | Stemline Therapeutics Inc | Rákos õssejt célzott rák elleni vakcinák |
| DK2877189T3 (da) * | 2012-07-20 | 2021-02-22 | Taiga Biotechnologies Inc | Forbedret rekonstituering og autorekonstituering af det hæmopoietiske kammer |
| US20160017011A1 (en) * | 2013-02-26 | 2016-01-21 | Rongfu Wang | Phf20 and jmjd3 compositions and methods of use in cancer immunotherapy |
| RU2671897C2 (ru) * | 2013-03-01 | 2018-11-07 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Способы получения из опухоли обогащенных популяций реактивных в отношении опухоли т-клеток |
| US9704181B2 (en) * | 2014-05-06 | 2017-07-11 | International Business Machines Corporation | Real-time social group based bidding system |
| IL281425B (en) | 2016-12-02 | 2022-07-01 | Taiga Biotechnologies Inc | Nanoparticle formulations |
| IL299051A (en) * | 2017-01-27 | 2023-02-01 | Immatics Biotechnologies Gmbh | New peptides and their combinations for immunotherapy against ovarian cancer and other cancers |
| AR110857A1 (es) | 2017-01-27 | 2019-05-08 | Immatics Biotechnologies Gmbh | Péptidos y combinaciones de péptidos para el uso en la inmunoterapia contra el cáncer de ovario y otros tipos de cáncer |
| MA47367B1 (fr) * | 2017-01-27 | 2023-06-28 | Immatics Biotechnologies Gmbh | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer de l'ovaire et d'autres cancers |
| MA53543A (fr) | 2018-09-04 | 2021-07-14 | Treos Bio Ltd | Vaccins peptidiques |
| CN113355432A (zh) * | 2021-05-12 | 2021-09-07 | 甘肃农业大学 | Bmf作为细胞凋亡标志物的应用 |
| WO2022245249A1 (ru) * | 2021-05-17 | 2022-11-24 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) | Пептидные соединения для индукции апоптоза в опухолевой клетке |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5554372A (en) | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US5342774A (en) | 1991-05-23 | 1994-08-30 | Ludwig Institute For Cancer Research | Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 |
| ATE280180T1 (de) | 1992-08-31 | 2004-11-15 | Ludwig Inst Cancer Res | Vom mage-3-gen abgeleitetes und von hla-a1 präsentiertes, isoliertes nonapeptid und dessen anwendungen |
| US5470955A (en) * | 1993-02-02 | 1995-11-28 | Dartmouth College | Antibodies which specifically bind mcl-1 polypeptide |
| US5646008A (en) * | 1993-06-22 | 1997-07-08 | The Regent Of The University Of Michigan | Vertebrate apoptosis gene: compositions and methods |
| US5700638A (en) | 1993-08-26 | 1997-12-23 | Washington University | Cell death regulator |
| GB9320597D0 (en) | 1993-10-06 | 1993-11-24 | Proteus Molecular Design | Improvements in and realting to vaccines |
| US6096313A (en) | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
| US5789201A (en) * | 1996-02-23 | 1998-08-04 | Cocensys, Inc. | Genes coding for bcl-y a bcl-2 homologue |
| AU736587B2 (en) | 1996-11-20 | 2001-08-02 | Yale University | Survivin, a protein that inhibits cellular apoptosis, and its modulation |
| WO1998058541A1 (en) * | 1997-06-24 | 1998-12-30 | Dana-Farber Cancer Institute, Inc. | Modulation of apoptosis |
| AU3471200A (en) | 1999-11-16 | 2001-05-30 | Dartmouth College | Mcl-1 gene regulatory elements and a pro-apoptotic mcl-1 variant |
| JP2003516744A (ja) | 1999-12-14 | 2003-05-20 | ザ バーナム インスティチュート | Ｂｃｌ−ｇポリペプチド、それをコードする核酸および使用方法 |
| AU2001271426A1 (en) | 2000-07-17 | 2002-01-30 | Washington University | Modulation of apoptosis |
| WO2002072627A2 (en) * | 2001-03-09 | 2002-09-19 | Callistogen Ag | Induction of anti-tumor cytotoxic t-lymphocytes in humans using peptide epitopes found by computer based algorithms for vaccination |
| US7892559B2 (en) | 2002-01-30 | 2011-02-22 | Survac Aps | Survivin-derived peptides and use thereof |
| EP1618130B1 (en) | 2003-04-11 | 2013-03-27 | Survac ApS | Therapeutic cancer vaccine |
-
2004
- 2004-11-18 WO PCT/DK2004/000799 patent/WO2005049073A2/en active Application Filing
- 2004-11-18 ES ES09154734.9T patent/ES2436429T3/es active Active
- 2004-11-18 EP EP09154734.9A patent/EP2087904B1/en active Active
- 2004-11-18 PL PL04797460T patent/PL1691824T3/pl unknown
- 2004-11-18 US US10/580,016 patent/US7842294B2/en active Active
- 2004-11-18 DK DK09154734.9T patent/DK2087904T3/da active
- 2004-11-18 KR KR1020067012186A patent/KR101216655B1/ko active IP Right Grant
- 2004-11-18 CN CN2004800407050A patent/CN1921878B/zh active Active
- 2004-11-18 AT AT04797460T patent/ATE424842T1/de active
- 2004-11-18 ES ES04797460T patent/ES2323588T3/es active Active
- 2004-11-18 PL PL09154734T patent/PL2087904T3/pl unknown
- 2004-11-18 DK DK04797460T patent/DK1691824T3/da active
- 2004-11-18 CA CA2546794A patent/CA2546794C/en active Active
- 2004-11-18 RU RU2006121466/15A patent/RU2367468C2/ru active
- 2004-11-18 MX MXPA06005738A patent/MXPA06005738A/es active IP Right Grant
- 2004-11-18 EP EP04797460A patent/EP1691824B1/en active Active
- 2004-11-18 JP JP2006540170A patent/JP4926714B2/ja active Active
- 2004-11-18 PT PT04797460T patent/PT1691824E/pt unknown
- 2004-11-18 ZA ZA200604866A patent/ZA200604866B/en unknown
- 2004-11-18 DE DE602004019965T patent/DE602004019965D1/de active Active
- 2004-11-18 AU AU2004290866A patent/AU2004290866B2/en active Active
- 2004-11-18 KR KR1020127016885A patent/KR101284237B1/ko active IP Right Grant
-
2007
- 2007-08-23 HK HK07109167.1A patent/HK1101131A1/xx unknown
-
2011
- 2011-09-12 JP JP2011198605A patent/JP5502823B2/ja active Active
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