DK168290B1 - 4-Amino-2,3-alkylen-quinolinderivater, en fremgangsmåde til deres fremstilling og anvendelse til fremstilling af et lægemiddel med aktivitet til lettelse af hukommelses-dysfunktion samt farmaceutisk præparat indeholdende et af de nævnte derivater - Google Patents

4-Amino-2,3-alkylen-quinolinderivater, en fremgangsmåde til deres fremstilling og anvendelse til fremstilling af et lægemiddel med aktivitet til lettelse af hukommelses-dysfunktion samt farmaceutisk præparat indeholdende et af de nævnte derivater Download PDF

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Publication number
DK168290B1
DK168290B1 DK571989A DK571989A DK168290B1 DK 168290 B1 DK168290 B1 DK 168290B1 DK 571989 A DK571989 A DK 571989A DK 571989 A DK571989 A DK 571989A DK 168290 B1 DK168290 B1 DK 168290B1
Authority
DK
Denmark
Prior art keywords
lower alkyl
formula
compound
hydrogen
given above
Prior art date
Application number
DK571989A
Other languages
Danish (da)
English (en)
Other versions
DK571989D0 (da
DK571989A (da
Inventor
Gregory Michael Shutske
Iv John Dick Tomer
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK571989D0 publication Critical patent/DK571989D0/da
Publication of DK571989A publication Critical patent/DK571989A/da
Application granted granted Critical
Publication of DK168290B1 publication Critical patent/DK168290B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
DK571989A 1988-11-16 1989-11-15 4-Amino-2,3-alkylen-quinolinderivater, en fremgangsmåde til deres fremstilling og anvendelse til fremstilling af et lægemiddel med aktivitet til lettelse af hukommelses-dysfunktion samt farmaceutisk præparat indeholdende et af de nævnte derivater DK168290B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27178888A 1988-11-16 1988-11-16
US27178888 1988-11-16

Publications (3)

Publication Number Publication Date
DK571989D0 DK571989D0 (da) 1989-11-15
DK571989A DK571989A (da) 1990-05-17
DK168290B1 true DK168290B1 (da) 1994-03-07

Family

ID=23037088

Family Applications (1)

Application Number Title Priority Date Filing Date
DK571989A DK168290B1 (da) 1988-11-16 1989-11-15 4-Amino-2,3-alkylen-quinolinderivater, en fremgangsmåde til deres fremstilling og anvendelse til fremstilling af et lægemiddel med aktivitet til lettelse af hukommelses-dysfunktion samt farmaceutisk præparat indeholdende et af de nævnte derivater

Country Status (15)

Country Link
EP (1) EP0369388B1 (es)
KR (1) KR0156241B1 (es)
AT (1) ATE89553T1 (es)
CA (1) CA2003023C (es)
DE (1) DE68906647T2 (es)
DK (1) DK168290B1 (es)
ES (1) ES2054987T3 (es)
FI (1) FI90417C (es)
HU (2) HU208674B (es)
IE (1) IE63038B1 (es)
IL (1) IL92307A0 (es)
NO (1) NO894547L (es)
NZ (1) NZ231376A (es)
PT (1) PT92319B (es)
ZA (1) ZA898720B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200462B (es) * 1990-09-27 1993-02-21 Hoechst Roussel Pharma
GB2264707A (en) * 1991-06-18 1993-09-08 Roger Michael Marchbanks Acridine derivatives for treating alzheimer's disease
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
WO2019207604A1 (en) * 2018-04-25 2019-10-31 Rajiv Gandhi Centre For Biotechnology Tacrine derivatives targeting nmda receptor, acetylcholine esterase, butyryl choline and beta secretase activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0179383B1 (en) * 1984-10-25 1991-05-29 Hoechst-Roussel Pharmaceuticals Incorporated 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments
NZ223875A (en) * 1987-03-17 1991-01-29 Hoechst Roussel Pharma 9-aminotetrahydroacridines and related homologues and pharmaceutical compositions

Also Published As

Publication number Publication date
KR900007809A (ko) 1990-06-02
ZA898720B (en) 1990-08-29
IE893659L (en) 1990-05-16
CA2003023C (en) 2001-05-29
ATE89553T1 (de) 1993-06-15
FI895416A0 (fi) 1989-11-14
NO894547L (no) 1990-05-18
IL92307A0 (en) 1990-07-26
DE68906647T2 (de) 1993-10-07
NO894547D0 (no) 1989-11-15
NZ231376A (en) 1992-05-26
HUT53087A (en) 1990-09-28
ES2054987T3 (es) 1994-08-16
FI90417B (fi) 1993-10-29
DK571989D0 (da) 1989-11-15
FI90417C (fi) 1994-02-10
HU895931D0 (en) 1990-02-28
PT92319B (pt) 1995-08-09
IE63038B1 (en) 1995-03-22
CA2003023A1 (en) 1990-05-16
PT92319A (pt) 1990-05-31
DE68906647D1 (de) 1993-06-24
KR0156241B1 (ko) 1998-11-16
EP0369388A1 (en) 1990-05-23
EP0369388B1 (en) 1993-05-19
DK571989A (da) 1990-05-17
HU208674B (en) 1993-12-28
HU211701A9 (en) 1995-12-28

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